A sustained deficiency of mitochondrial respiratory complex III induces an apoptotic cell death through the p53-mediated inhibition of pro-survival activities of the activating transcription factor 4

Cell Death and Disease

Volumn 5, Issue 11, 2014, Pages

  Evstafieva, A G ^a   Garaeva, A A ^a   Khutornenko, A A ^a   Klepikova, A V ^a   Logacheva, M D ^a   Penin, A A ^a   Novakovsky, G E ^a   Kovaleva, I E ^a   Chumakov, P M ^b  

^a MOSCOW STATE UNIVERSITY   (Russian Federation)

^b ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; AMINO ACID TRANSFER RNA LIGASE; AMINO ACID TRANSPORTER; APOPTOSIS INHIBITOR; DIHYDROOROTATE DEHYDROGENASE; INITIATION FACTOR 2ALPHA; MESSENGER RNA; MYXOTHIAZOL; PROTEIN P53; PYRIMIDINE DERIVATIVE; UBIQUINOL CYTOCHROME C REDUCTASE; URIDINE; ATF4 PROTEIN, HUMAN; INITIATION FACTOR 2; METHACRYLIC ACID DERIVATIVE; OXIDOREDUCTASE; PIERICIDIN A; PYRIDINE DERIVATIVE; THIAZOLE DERIVATIVE;

APOPTOSIS; ARTICLE; BIOSYNTHESIS; CARCINOMA CELL LINE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; HCT116 CELL LINE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MITOCHONDRIAL RESPIRATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RESPIRATORY CHAIN; SUPPLEMENTATION; CELL SURVIVAL; DEFICIENCY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MITOCHONDRION; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ACTIVATING TRANSCRIPTION FACTOR 4; APOPTOSIS; CELL LINE, TUMOR; CELL SURVIVAL; ELECTRON TRANSPORT COMPLEX III; EUKARYOTIC INITIATION FACTOR-2; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; METHACRYLATES; MITOCHONDRIA; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; PHOSPHORYLATION; PYRIDINES; PYRIMIDINES; RNA, MESSENGER; SIGNAL TRANSDUCTION; THIAZOLES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84927942635     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2014.469     Document Type: Article

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