A polysaccharide from Andrographis paniculata induces mitochondrial-mediated apoptosis in human hepatoma cell line (HepG2)

Tumor Biology

Volumn 36, Issue 7, 2015, Pages 5179-5186

  Zou, Yanmei ^a   Xiong, Hua ^a   Xiong, Huihua ^a   Lu, Tao ^b   Zhu, Feng ^b   Luo, Zhiyong ^a   Yuan, Xianglin ^a   Wang, Yihua ^c  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Andrographis paniculata; Apoptosis; Hepatocellular carcinoma; Mitochondria; Polysaccharides

Indexed keywords

ANDROGRAPHIS PANICULATA PURIFIED POLYSACCHARIDE; ANTINEOPLASTIC AGENT; ARABINOSE; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; FUCOSE; GALACTOSE; GALACTURONIC ACID; GLUCOSE; GLUCURONIC ACID; HERBACEOUS AGENT; INOSITOL; MANNOSE; PROTEIN; PROTEIN BAX; PROTEIN BCL 2; RHAMNOSE; UNCLASSIFIED DRUG; URONIC ACID; XYLOSE; POLYSACCHARIDE;

ANDROGRAPHIS PANICULATA; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG ISOLATION; DRUG MECHANISM; DRUG PURIFICATION; DRUG SCREENING; ENZYME ACTIVATION; ENZYME ACTIVITY; HEPG2 CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRACELLULAR SIGNALING; LIVER CELL CARCINOMA; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANDROGRAPHIS; BIOSYNTHESIS; CARCINOMA, HEPATOCELLULAR; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; LIVER NEOPLASMS; PATHOLOGY; SIGNAL TRANSDUCTION;

ANDROGRAPHIS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CARCINOMA, HEPATOCELLULAR; CASPASE 3; CASPASE 9; CELL PROLIFERATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; MITOCHONDRIA; POLYSACCHARIDES; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION;

EID: 84938204799     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-015-3172-1     Document Type: Article

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