Astrocyte elevated gene-1 (AEG-1) shRNA sensitizes Huaier polysaccharide (HP)-induced anti-metastatic potency via inactivating downstream P13K/Akt pathway as well as augmenting cell-mediated immune response

Tumor Biology

Volumn 35, Issue 5, 2014, Pages 4219-4224

  Zheng, Jiasheng ^a   Li, Cong ^a   Wu, Xia ^b   Liu, Mengmeng ^b   Sun, Xicai ^c   Yang, Yingzhuo ^b   Hao, Meijun ^a   Sheng, Shoupeng ^a   Sun, Yu ^a   Zhang, Honghai ^a   Long, Jiang ^a   Liang, Yi ^d,e   Hu, Caixia ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b HARBIN MEDICAL UNIVERSITY   (China)

^c Tsinghua University   (China)

^d GUIZHOU MEDICAL UNIVERSITY   (China)

^e SHENYANG MEDICAL COLLEGE   (China)

Author keywords

Anti metastasis; Astrocyte elevated gene 1 (AEG 1); Hepatocellular carcinoma (HCC); Huaier polysaccharide; MHCC97 H cells; NK cell; P13K Akt pathway

Indexed keywords

ANTINEOPLASTIC AGENT; HUAIER POLYSACCHARIDE; PHOSPHATIDYLINOSITOL 3 KINASE; POLYSACCHARIDE; PROTEIN KINASE B; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; CELL ADHESION MOLECULE; MTDH PROTEIN, HUMAN; SMALL INTERFERING RNA;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; ASTROCYTE ELEVATED GENE 1; CANCER INHIBITION; CELL ACTIVITY; CELL INVASION; CELL MIGRATION; CELLULAR IMMUNITY; CONTROLLED STUDY; DOWN REGULATION; GENE; HEPATOCELLULAR CARCINOMA CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CELL CARCINOMA; METASTASIS INHIBITION; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR INVASION; CHEMISTRY; DRUG ANTAGONISM; GENETICS; IMMUNOLOGY; LIVER TUMOR; METASTASIS; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; TRAMETES; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CARCINOMA, HEPATOCELLULAR; CELL ADHESION MOLECULES; CELL LINE, TUMOR; HUMANS; KILLER CELLS, NATURAL; LIVER NEOPLASMS; NEOPLASM METASTASIS; PHOSPHATIDYLINOSITOL 3-KINASES; POLYSACCHARIDES; PROTO-ONCOGENE PROTEINS C-AKT; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRAMETES;

EID: 84902953844     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-013-1552-y     Document Type: Article

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