β-catenin destruction complex-independent regulation of Hippo-YAP signaling by APC in intestinal tumorigenesis

Genes and Development

Volumn 29, Issue 14, 2015, Pages 1493-1506

  Cai, Jing ^a   Maitra, Anirban ^b   Anders, Robert A ^a   Taketo, Makoto M ^c   Pan, Duojia ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^c KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

APC; Hippo signaling; TAZ; Tumorigenesis; YAP; catenin

Indexed keywords

BETA CATENIN; SCAFFOLD PROTEIN; APC PROTEIN; HIPPO PROTEIN, HUMAN; HIPPO PROTEIN, MOUSE; PHOSPHOPROTEIN; PROTEIN SERINE THREONINE KINASE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; YAP PROTEIN, MOUSE; YAP1 (YES-ASSOCIATED) PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CANCER PATIENT; CELL LYSATE; COLON POLYPOSIS; COLORECTAL POLYP; FAMILIAL COLON POLYPOSIS; GENE MUTATION; HEK293 CELL LINE; HIPPO YAP SIGNALING; HUMAN; HUMAN CELL; INTESTINE TUMOR; MOUSE; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; WESTERN BLOTTING; WNT SIGNALING PATHWAY; ADENOMA; ANIMAL; CARCINOGENESIS; CELL CULTURE; ENZYMOLOGY; GENETICS; INTESTINE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOMA; ADENOMATOUS POLYPOSIS COLI; ADENOMATOUS POLYPOSIS COLI PROTEIN; ANIMALS; BETA CATENIN; CARCINOGENESIS; CELLS, CULTURED; HUMANS; INTESTINES; MICE; PHOSPHOPROTEINS; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION;

EID: 84938093437     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.264515.115     Document Type: Article

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