Protein interaction network of the mammalian hippo pathway reveals mechanisms of kinase-phosphatase interactions

Science Signaling

Volumn 6, Issue 302, 2013, Pages

  Couzens, Amber L ^a   Knight, James D R ^a   Kean, Michelle J ^a,b   Teo, Guoci ^c   Weiss, Alexander ^a   Dunham, Wade H ^a   Lin, Zhen Yuan ^a   Bagshaw, Richard D ^a   Sicheri, Frank ^a,b   Pawson, Tony ^a,b   Wrana, Jeffrey L ^a,b   Choi, Hyungwon ^d   Gingras, Anne Claude ^a,b,e  

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d NATIONAL UNIVERSITY HEALTH SYSTEM   (Singapore)

^e ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; AURORA B KINASE; KINESIN; MEMBRANE PROTEIN; OKADAIC ACID; PHOSPHATASE; PHOSPHOTRANSFERASE; POLO LIKE KINASE 1; PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE; SERINE; THREONINE; TRANSCRIPTION FACTOR YAP1; HIPPO PROTEIN, HUMAN; LUCIFERASE; MOB1A PROTEIN, HUMAN; MOB1B PROTEIN, HUMAN; PHOSPHOPROTEIN PHOSPHATASE; PHOTOPROTEIN; PROTEIN PHOSPHATASE 6; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SLMAP PROTEIN, HUMAN; STK3 PROTEIN, HUMAN; STK4 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; AUTOPHOSPHORYLATION; BIOTINYLATION; CELL JUNCTION; CELL MEMBRANE; CELL POLARITY; COMPLEX FORMATION; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HIPPO SIGNALING PATHWAY; HUMAN; HUMAN CELL; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPHOSPHORYLATION; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; ANIMAL; BINDING SITE; CLASSIFICATION; CLUSTER ANALYSIS; GENETICS; HEK293 CELL LINE; HELA CELL LINE; METABOLISM; METHODOLOGY; MUTATION; PHOSPHORYLATION; PROTEIN ANALYSIS; WESTERN BLOTTING;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BINDING SITES; BLOTTING, WESTERN; CLUSTER ANALYSIS; HEK293 CELLS; HELA CELLS; HUMANS; LUCIFERASES; LUMINESCENT PROTEINS; MEMBRANE PROTEINS; MUTATION; PHOSPHOPROTEIN PHOSPHATASES; PHOSPHORIC MONOESTER HYDROLASES; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; PROTEIN INTERACTION MAPS; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION;

EID: 84888100485     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2004712     Document Type: Article

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