-
1
-
-
84855784320
-
Willin/FRMD6 expression activates the Hippo signaling pathway kinases in mammals and antagonizes oncogenic YAP
-
Angus L, Moleirinho S, Herron L, Sinha A, Zhang X, Niestrata M, Dholakia K, Prystowsky MB, Harvey KF, Reynolds PA, Gunn-Moore FJ (2012) Willin/FRMD6 expression activates the Hippo signaling pathway kinases in mammals and antagonizes oncogenic YAP. Oncogene 31: 238-250
-
(2012)
Oncogene
, vol.31
, pp. 238-250
-
-
Angus, L.1
Moleirinho, S.2
Herron, L.3
Sinha, A.4
Zhang, X.5
Niestrata, M.6
Dholakia, K.7
Prystowsky, M.B.8
Harvey, K.F.9
Reynolds, P.A.10
Gunn-Moore, F.J.11
-
2
-
-
24744439504
-
Multiple microalterations detected at high frequency in oral cancer
-
Baldwin C, Garnis C, Zhang LW, Rosin MP, Lam WL (2005) Multiple microalterations detected at high frequency in oral cancer. Cancer Res 65: 7561-7567
-
(2005)
Cancer Res
, vol.65
, pp. 7561-7567
-
-
Baldwin, C.1
Garnis, C.2
Zhang, L.W.3
Rosin, M.P.4
Lam, W.L.5
-
3
-
-
22044450542
-
Array-based comparative genomic hybridization identifies localized DNA amplifications and homozygous deletions in pancreatic cancer
-
Bashyam MD, Bair R, Kim YH, Wang P, Hernandez-Boussard T, Karikari CA, Tibshirani R, Maitra A, Pollack JR (2005) Array-based comparative genomic hybridization identifies localized DNA amplifications and homozygous deletions in pancreatic cancer. Neoplasia 7: 556-562
-
(2005)
Neoplasia
, vol.7
, pp. 556-562
-
-
Bashyam, M.D.1
Bair, R.2
Kim, Y.H.3
Wang, P.4
Hernandez-Boussard, T.5
Karikari, C.A.6
Tibshirani, R.7
Maitra, A.8
Pollack, J.R.9
-
4
-
-
76249125346
-
The WW domain protein kibra acts upstream of Hippo in Drosophila
-
Baumgartner R, Poernbacher I, Buser N, Hafen E, Stocker H (2010) The WW domain protein kibra acts upstream of Hippo in Drosophila. Developmental Cell 18: 309-316
-
(2010)
Developmental Cell
, vol.18
, pp. 309-316
-
-
Baumgartner, R.1
Poernbacher, I.2
Buser, N.3
Hafen, E.4
Stocker, H.5
-
5
-
-
78049451932
-
The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program
-
Cai J, Zhang N, Zheng Y, de Wilde RF, Maitra A, Pan D (2010) The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program. Genes Dev 24: 2383-2388
-
(2010)
Genes Dev
, vol.24
, pp. 2383-2388
-
-
Cai, J.1
Zhang, N.2
Zheng, Y.3
De Wilde, R.F.4
Maitra, A.5
Pan, D.6
-
6
-
-
36549074631
-
YAP1 increases organ size and expands undifferentiated progenitor cells
-
Camargo FD, Gokhale S, Johnnidis JB, Fu D, Bell GW, Jaenisch R, Brummelkamp TR (2007) YAP1 increases organ size and expands undifferentiated progenitor cells. Curr Biol 17: 2054-2060
-
(2007)
Curr Biol
, vol.17
, pp. 2054-2060
-
-
Camargo, F.D.1
Gokhale, S.2
Johnnidis, J.B.3
Fu, D.4
Bell, G.W.5
Jaenisch, R.6
Brummelkamp, T.R.7
-
7
-
-
57749122174
-
YAP regulates neural progenitor cell number via the TEA domain transcription factor
-
Cao X, Pfaff SL, Gage FH (2008) YAP regulates neural progenitor cell number via the TEA domain transcription factor. Genes Dev 22: 3320-3334
-
(2008)
Genes Dev
, vol.22
, pp. 3320-3334
-
-
Cao, X.1
Pfaff, S.L.2
Gage, F.H.3
-
8
-
-
33746362123
-
Delineation of type i protein kinase A-selective signaling events using an RI anchoring disruptor
-
Carlson CR, Lygren B, Berge T, Hoshi N, Wong W, Tasken K, Scott JD (2006) Delineation of type I protein kinase A-selective signaling events using an RI anchoring disruptor. J Biol Chem 281: 21535-21545
-
(2006)
J Biol Chem
, vol.281
, pp. 21535-21545
-
-
Carlson, C.R.1
Lygren, B.2
Berge, T.3
Hoshi, N.4
Wong, W.5
Tasken, K.6
Scott, J.D.7
-
9
-
-
0026348474
-
Interaction of the regulatory subunit (RII) of cAMP-dependent protein kinase with RII-anchoring proteins occurs through an amphipathic helix binding motif
-
Carr DW, Stofko-Hahn RE, Fraser ID, Bishop SM, Acott TS, Brennan RG, Scott JD (1991) Interaction of the regulatory subunit (RII) of cAMP-dependent protein kinase with RII-anchoring proteins occurs through an amphipathic helix binding motif. J Biol Chem 266: 14188-14192
-
(1991)
J Biol Chem
, vol.266
, pp. 14188-14192
-
-
Carr, D.W.1
Stofko-Hahn, R.E.2
Fraser, I.D.3
Bishop, S.M.4
Acott, T.S.5
Brennan, R.G.6
Scott, J.D.7
-
10
-
-
16444373346
-
The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1
-
Chan EH, Nousiainen M, Chalamalasetty RB, Schafer A, Nigg EA, Sillje HH (2005) The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1. Oncogene 24: 2076-2086
-
(2005)
Oncogene
, vol.24
, pp. 2076-2086
-
-
Chan, E.H.1
Nousiainen, M.2
Chalamalasetty, R.B.3
Schafer, A.4
Nigg, E.A.5
Sillje, H.H.6
-
11
-
-
79953223677
-
Hippo pathway-independent restriction of TAZ and YAP by angiomotin
-
Chan SW, Lim CJ, Chong YF, Pobbati AV, Huang C, Hong W (2011a) Hippo pathway-independent restriction of TAZ and YAP by angiomotin. J Biol Chem 286: 7018-7026
-
(2011)
J Biol Chem
, vol.286
, pp. 7018-7026
-
-
Chan, S.W.1
Lim, C.J.2
Chong, Y.F.3
Pobbati, A.V.4
Huang, C.5
Hong, W.6
-
12
-
-
79953223677
-
Hippo pathway-independent restriction of TAZ and YAP by angiomotin
-
Chan SW, Lim CJ, Chong YF, Pobbati AV, Huang CX, Hong WJ (2011b) Hippo pathway-independent restriction of TAZ and YAP by angiomotin. J Biol Chem 286: 7018-7026
-
(2011)
J Biol Chem
, vol.286
, pp. 7018-7026
-
-
Chan, S.W.1
Lim, C.J.2
Chong, Y.F.3
Pobbati, A.V.4
Huang, C.X.5
Hong, W.J.6
-
13
-
-
0023665050
-
Inhibition of intracellular cAMP-dependent protein kinase using mutant genes of the regulatory type i subunit
-
Clegg CH, Correll LA, Cadd GG, McKnight GS (1987) Inhibition of intracellular cAMP-dependent protein kinase using mutant genes of the regulatory type I subunit. J Biol Chem 262: 13111-13119
-
(1987)
J Biol Chem
, vol.262
, pp. 13111-13119
-
-
Clegg, C.H.1
Correll, L.A.2
Cadd, G.G.3
McKnight, G.S.4
-
14
-
-
0034608016
-
Activated 30,5 0-cyclic AMP-dependent protein kinase is sufficient to induce neuroendocrine-like differentiation of the LNCaP prostate tumor cell line
-
Cox ME, Deeble PD, Bissonette EA, Parsons SJ (2000) Activated 30,5 0-cyclic AMP-dependent protein kinase is sufficient to induce neuroendocrine-like differentiation of the LNCaP prostate tumor cell line. J Biol Chem 275: 13812-13818
-
(2000)
J Biol Chem
, vol.275
, pp. 13812-13818
-
-
Cox, M.E.1
Deeble, P.D.2
Bissonette, E.A.3
Parsons, S.J.4
-
15
-
-
0037388691
-
A comprehensive search for DNA amplification in lung cancer identifies inhibitors of apoptosis cIAP1 and cIAP2 as candidate oncogenes
-
Dai ZY, Zhu WG, Morrison CD, Brena RM, Smiraglia DJ, Raval A, Wu YZ, Rush LJ, Ross P, Molina JR, Otterson GA, Plass C (2003) A comprehensive search for DNA amplification in lung cancer identifies inhibitors of apoptosis cIAP1 and cIAP2 as candidate oncogenes. Hum Mol Genet 12: 791-801
-
(2003)
Hum Mol Genet
, vol.12
, pp. 791-801
-
-
Dai, Z.Y.1
Zhu, W.G.2
Morrison, C.D.3
Brena, R.M.4
Smiraglia, D.J.5
Raval, A.6
Wu, Y.Z.7
Rush, L.J.8
Ross, P.9
Molina, J.R.10
Otterson, G.A.11
Plass, C.12
-
16
-
-
0024576161
-
A protein-kinase inhibitor gene reduces both basal and multihormone-stimulated prolactin gene-transcription
-
Day RN, Walder JA, Maurer RA (1989) A protein-kinase inhibitor gene reduces both basal and multihormone-stimulated prolactin gene-transcription. J Biol Chem 264: 431-436
-
(1989)
J Biol Chem
, vol.264
, pp. 431-436
-
-
Day, R.N.1
Walder, J.A.2
Maurer, R.A.3
-
17
-
-
0032480888
-
Epac is a Rap1 guanine-nucleotideexchange factor directly activated by cyclic AMP
-
De Rooij J, Zwartkruis FJT, Verheijen MHG, Cool RH, Nijman SMB, Wittinghofer A, Bos JL (1998) Epac is a Rap1 guanine-nucleotideexchange factor directly activated by cyclic AMP. Nature 396: 474-477
-
(1998)
Nature
, vol.396
, pp. 474-477
-
-
De Rooij, J.1
Fjt, Z.2
Mhg, V.3
Cool, R.H.4
Smb, N.5
Wittinghofer, A.6
Bos, J.L.7
-
18
-
-
34548636132
-
Elucidation of a universal size-control mechanism in Drosophila and mammals
-
Dong J, Feldmann G, Huang J, Wu S, Zhang N, Comerford SA, Gayyed MF, Anders RA, Maitra A, Pan D (2007) Elucidation of a universal size-control mechanism in Drosophila and mammals. Cell 130: 1120-1133
-
(2007)
Cell
, vol.130
, pp. 1120-1133
-
-
Dong, J.1
Feldmann, G.2
Huang, J.3
Wu, S.4
Zhang, N.5
Comerford, S.A.6
Gayyed, M.F.7
Anders, R.A.8
Maitra, A.9
Pan, D.10
-
19
-
-
0031033178
-
Ezrin is a cyclic AMP-dependent protein kinase anchoring protein
-
Dransfield DT, Bradford AJ, Smith J, Martin M, Roy C, Mangeat PH, Goldenring JR (1997) Ezrin is a cyclic AMP-dependent protein kinase anchoring protein. EMBO J 16: 35-43
-
(1997)
EMBO J
, vol.16
, pp. 35-43
-
-
Dransfield, D.T.1
Bradford, A.J.2
Smith, J.3
Martin, M.4
Roy, C.5
Mangeat, P.H.6
Goldenring, J.R.7
-
20
-
-
79958284636
-
Role of YAP/TAZ in mechanotransduction
-
Dupont S, Morsut L, Aragona M, Enzo E, Giulitti S, Cordenonsi M, Zanconato F, Le Digabel J, Forcato M, Bicciato S, Elvassore N, Piccolo S (2011) Role of YAP/TAZ in mechanotransduction. Nature 474: 179-183
-
(2011)
Nature
, vol.474
, pp. 179-183
-
-
Dupont, S.1
Morsut, L.2
Aragona, M.3
Enzo, E.4
Giulitti, S.5
Cordenonsi, M.6
Zanconato, F.7
Le Digabel, J.8
Forcato, M.9
Bicciato, S.10
Elvassore, N.11
Piccolo, S.12
-
21
-
-
79956327002
-
Actin-capping protein and the Hippo pathway regulate F-actin and tissue growth in Drosophila
-
Fernandez BG, Gaspar P, Bras-Pereira C, Jezowska B, Rebelo SR, Janody F (2011) Actin-capping protein and the Hippo pathway regulate F-actin and tissue growth in Drosophila. Development 138: 2337-2346
-
(2011)
Development
, vol.138
, pp. 2337-2346
-
-
Fernandez, B.G.1
Gaspar, P.2
Bras-Pereira, C.3
Jezowska, B.4
Rebelo, S.R.5
Janody, F.6
-
22
-
-
0020613837
-
Regulation of the catalytic component of adenylate cyclase. Potentiative interaction of stimulatory ligands and 20,50-dideoxyadenosine
-
Florio VA, Ross EM (1983) Regulation of the catalytic component of adenylate cyclase. Potentiative interaction of stimulatory ligands and 20,50-dideoxyadenosine. Mol Pharmacol 24: 195-202
-
(1983)
Mol Pharmacol
, vol.24
, pp. 195-202
-
-
Florio, V.A.1
Ross, E.M.2
-
23
-
-
76249093838
-
Kibra is a regulator of the Salvador/Warts/Hippo signaling network
-
Genevet A, Wehr MC, Brain R, Thompson BJ, Tapon N (2010) Kibra is a regulator of the Salvador/Warts/Hippo signaling network. Dev Cell 18: 300-308
-
(2010)
Dev Cell
, vol.18
, pp. 300-308
-
-
Genevet, A.1
Wehr, M.C.2
Brain, R.3
Thompson, B.J.4
Tapon, N.5
-
24
-
-
33750480828
-
Molecular basis of AKAP specificity for PKA regulatory subunits
-
Gold MG, Lygren B, Dokurno P, Hoshi N, McConnachie G, Tasken K, Carlson CR, Scott JD, Barford D (2006) Molecular basis of AKAP specificity for PKA regulatory subunits. Mol Cell 24: 383-395
-
(2006)
Mol Cell
, vol.24
, pp. 383-395
-
-
Gold, M.G.1
Lygren, B.2
Dokurno, P.3
Hoshi, N.4
McConnachie, G.5
Tasken, K.6
Carlson, C.R.7
Scott, J.D.8
Barford, D.9
-
25
-
-
3042611874
-
Merlin links to the cAMP neuronal signaling pathway by anchoring the RIbeta subunit of protein kinase A
-
Gronholm M, Vossebein L, Carlson CR, Kuja-Panula J, Teesalu T, Alfthan K, Vaheri A, Rauvala H, Herberg FW, Tasken K, Carpen O (2003) Merlin links to the cAMP neuronal signaling pathway by anchoring the RIbeta subunit of protein kinase A. J Biol Chem 278: 41167-41172
-
(2003)
J Biol Chem
, vol.278
, pp. 41167-41172
-
-
Gronholm, M.1
Vossebein, L.2
Carlson, C.R.3
Kuja-Panula, J.4
Teesalu, T.5
Alfthan, K.6
Vaheri, A.7
Rauvala, H.8
Herberg, F.W.9
Tasken, K.10
Carpen, O.11
-
27
-
-
84865411430
-
Transduction of mechanical and cytoskeletal cues by YAP and TAZ
-
Halder G, Dupont S, Piccolo S (2012) Transduction of mechanical and cytoskeletal cues by YAP and TAZ. Nat Rev Mol Cell Biol 13: 591-600
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, pp. 591-600
-
-
Halder, G.1
Dupont, S.2
Piccolo, S.3
-
28
-
-
78650724753
-
Hippo signaling: Growth control and beyond
-
Halder G, Johnson RL (2011) Hippo signaling: growth control and beyond. Development 138: 9-22
-
(2011)
Development
, vol.138
, pp. 9-22
-
-
Halder, G.1
Johnson, R.L.2
-
29
-
-
30344445706
-
The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis
-
Hamaratoglu F, Willecke M, Kango-Singh M, Nolo R, Hyun E, Tao CY, Jafar-Nejad H, Halder G (2006) The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis. Nat Cell Biol 8: 27-U29
-
(2006)
Nat Cell Biol
, vol.8
, pp. 27-29
-
-
Hamaratoglu, F.1
Willecke, M.2
Kango-Singh, M.3
Nolo, R.4
Hyun, E.5
Tao, C.Y.6
Jafar-Nejad, H.7
Halder, G.8
-
30
-
-
33847206401
-
The Salvador-Warts-Hippo pathway - An emerging tumour-suppressor network
-
Harvey K, Tapon N (2007) The Salvador-Warts-Hippo pathway - an emerging tumour-suppressor network. Nat Rev Cancer 7: 182-191
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 182-191
-
-
Harvey, K.1
Tapon, N.2
-
31
-
-
33646422520
-
The human tumour suppressor LATS1 is activated by human MOB1 at the membrane
-
Hergovich A, Schmitz D, Hemmings BA (2006) The human tumour suppressor LATS1 is activated by human MOB1 at the membrane. Biochem Biophys Res Co 345: 50-58
-
(2006)
Biochem Biophys Res Co
, vol.345
, pp. 50-58
-
-
Hergovich, A.1
Schmitz, D.2
Hemmings, B.A.3
-
32
-
-
22744434487
-
Chromosomal changes in relation to clinical outcome in larynx and pharynx squamous cell carcinoma
-
Hermsen M, Guervos MA, Meijer G, van Diest P, Nieto CS, Marcos CA, Sampedro A (2005) Chromosomal changes in relation to clinical outcome in larynx and pharynx squamous cell carcinoma. Cell Oncol 27: 191-198
-
(2005)
Cell Oncol
, vol.27
, pp. 191-198
-
-
Hermsen, M.1
Guervos, M.A.2
Meijer, G.3
Van Diest, P.4
Nieto, C.S.5
Marcos, C.A.6
Sampedro, A.7
-
33
-
-
0034282225
-
Regulation of anchorage-dependent signal transduction by protein kinase A and p21-activated kinase
-
Howe AK, Juliano RL (2000) Regulation of anchorage-dependent signal transduction by protein kinase A and p21-activated kinase. Nat Cell Biol 2: 593-600
-
(2000)
Nat Cell Biol
, vol.2
, pp. 593-600
-
-
Howe, A.K.1
Juliano, R.L.2
-
34
-
-
23744458034
-
The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP
-
Huang J, Wu S, Barrera J, Matthews K, Pan D (2005) The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP. Cell 122: 421-434
-
(2005)
Cell
, vol.122
, pp. 421-434
-
-
Huang, J.1
Wu, S.2
Barrera, J.3
Matthews, K.4
Pan, D.5
-
35
-
-
0036733756
-
Expression of cIAP1, a target for 11q22 amplification, correlates with resistance of cervical cancers to radiotherapy
-
Imoto I, Tsuda H, Hirasawa A, Miura M, Sakamoto M, Hirohashi S, Inazawa J (2002) Expression of cIAP1, a target for 11q22 amplification, correlates with resistance of cervical cancers to radiotherapy. Cancer Res 62: 4860-4866
-
(2002)
Cancer Res
, vol.62
, pp. 4860-4866
-
-
Imoto, I.1
Tsuda, H.2
Hirasawa, A.3
Miura, M.4
Sakamoto, M.5
Hirohashi, S.6
Inazawa, J.7
-
36
-
-
0035884398
-
Identification of cIAP1 as a candidate target gene within an amplicon at 11q22 in esophageal squamous cell carcinomas
-
Imoto I, Yang ZQ, Pimkhaokham A, Tsuda H, Shimada Y, Imamura M, Ohki M, Inazawa J (2001) Identification of cIAP1 as a candidate target gene within an amplicon at 11q22 in esophageal squamous cell carcinomas. Cancer Res 61: 6629-6634
-
(2001)
Cancer Res
, vol.61
, pp. 6629-6634
-
-
Imoto, I.1
Yang, Z.Q.2
Pimkhaokham, A.3
Tsuda, H.4
Shimada, Y.5
Imamura, M.6
Ohki, M.7
Inazawa, J.8
-
37
-
-
79953139076
-
TopBP1 deficiency causes an early embryonic lethality and induces cellular senescence in primary cells
-
Jeon Y, Ko E, Lee KY, Ko MJ, Park SY, Kang J, Jeon CH, Lee H, Hwang DS (2011) TopBP1 deficiency causes an early embryonic lethality and induces cellular senescence in primary cells. J Biol Chem 286: 5414-5422
-
(2011)
J Biol Chem
, vol.286
, pp. 5414-5422
-
-
Jeon, Y.1
Ko, E.2
Lee, K.Y.3
Ko, M.J.4
Park, S.Y.5
Kang, J.6
Jeon, C.H.7
Lee, H.8
Hwang, D.S.9
-
38
-
-
84878564003
-
LMO4 controls the balance between excitatory and inhibitory spinal V2 interneurons
-
Joshi K, Lee S, Lee B, Lee JW, Lee SK (2009) LMO4 controls the balance between excitatory and inhibitory spinal V2 interneurons. Mech Develop 126: S139-S139
-
(2009)
Mech Develop
, vol.126
-
-
Joshi, K.1
Lee, S.2
Lee, B.3
Lee, J.W.4
Lee, S.K.5
-
39
-
-
24044528210
-
CAMP induces neuronal differentiation of mesenchymal stem cells via activation of extracellular signal-regulated kinase/MAPK
-
Kim SS, Choi JM, Kim JW, Ham DS, Ghil SH, Kim MK, Yunhee KK, Hong SY, Ahn SC, Kim SU, Lee YD, Haeyoung SK (2005) cAMP induces neuronal differentiation of mesenchymal stem cells via activation of extracellular signal-regulated kinase/MAPK. Neuroreport 16: 1357-1361
-
(2005)
Neuroreport
, vol.16
, pp. 1357-1361
-
-
Kim, S.S.1
Choi, J.M.2
Kim, J.W.3
Ham, D.S.4
Ghil, S.H.5
Kim, M.K.6
Yunhee, K.K.7
Hong, S.Y.8
Ahn, S.C.9
Kim, S.U.10
Lee, Y.D.11
Haeyoung, S.K.12
-
40
-
-
84863357474
-
Anoikis resistance: An essential prerequisite for tumor metastasis
-
Kim YN, Koo KH, Sung JY, Yun UJ, Kim H (2012) Anoikis resistance: an essential prerequisite for tumor metastasis. Int J Cell Biol 2012: 306879
-
(2012)
Int J Cell Biol
, vol.2012
, pp. 306879
-
-
Kim, Y.N.1
Koo, K.H.2
Sung, J.Y.3
Yun, U.J.4
Kim, H.5
-
41
-
-
42449101282
-
A crucial role of WW45 in developing epithelial tissues in the mouse
-
Lee JH, Kim TS, Yang TH, Koo BK, Oh SP, Lee KP, Oh HJ, Lee SH, Kong YY, Kim JM, Lim DS (2008) A crucial role of WW45 in developing epithelial tissues in the mouse. EMBO J 27: 1231-1242
-
(2008)
EMBO J
, vol.27
, pp. 1231-1242
-
-
Lee, J.H.1
Kim, T.S.2
Yang, T.H.3
Koo, B.K.4
Oh, S.P.5
Lee, K.P.6
Oh, H.J.7
Lee, S.H.8
Kong, Y.Y.9
Kim, J.M.10
Lim, D.S.11
-
42
-
-
77952336576
-
The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis
-
Lee KP, Lee JH, Kim TS, Kim TH, Park HD, Byun JS, Kim MC, Jeong WI, Calvisi DF, Kim JM, Lim DS (2010) The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis. Proc Natl Acad Sci USA 107: 8248-8253
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 8248-8253
-
-
Lee, K.P.1
Lee, J.H.2
Kim, T.S.3
Kim, T.H.4
Park, H.D.5
Byun, J.S.6
Kim, M.C.7
Jeong, W.I.8
Calvisi, D.F.9
Kim, J.M.10
Lim, D.S.11
-
43
-
-
34548067125
-
Cholera toxin induces malignant glioma cell differentiation via the PKA/ CREB pathway
-
Li Y, Yin W, Wang X, Zhu WB, Huang YJ, Yan GM (2007) Cholera toxin induces malignant glioma cell differentiation via the PKA/ CREB pathway. Proc Natl Acad Sci USA 104: 13438-13443
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 13438-13443
-
-
Li, Y.1
Yin, W.2
Wang, X.3
Zhu, W.B.4
Huang, Y.J.5
Yan, G.M.6
-
44
-
-
76549124517
-
Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver
-
Lu L, Li Y, Kim SM, Bossuyt W, Liu P, Qiu Q, Wang Y, Halder G, Finegold MJ, Lee JS, Johnson RL (2010) Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver. Proc Natl Acad Sci USA 107: 1437-1442
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 1437-1442
-
-
Lu, L.1
Li, Y.2
Kim, S.M.3
Bossuyt, W.4
Liu, P.5
Qiu, Q.6
Wang, Y.7
Halder, G.8
Finegold, M.J.9
Lee, J.S.10
Johnson, R.L.11
-
45
-
-
0035882281
-
A high-efficiency protein transduction system demonstrating the role of PKA in long-lasting long-term potentiation
-
Matsushita M, Tomizawa K, Moriwaki A, Li ST, Terada H, Matsui H (2001) A high-efficiency protein transduction system demonstrating the role of PKA in long-lasting long-term potentiation. J Neurosci 21: 6000-6007
-
(2001)
J Neurosci
, vol.21
, pp. 6000-6007
-
-
Matsushita, M.1
Tomizawa, K.2
Moriwaki, A.3
Li, S.T.4
Terada, H.5
Matsui, H.6
-
46
-
-
79960733700
-
Ezrin, radixin and moesin: Key regulators of membrane-cortex interactions and signaling
-
Neisch AL, Fehon RG (2011) Ezrin, radixin and moesin: key regulators of membrane-cortex interactions and signaling. Curr Opin Cell Biol 23: 377-382
-
(2011)
Curr Opin Cell Biol
, vol.23
, pp. 377-382
-
-
Neisch, A.L.1
Fehon, R.G.2
-
47
-
-
0030861621
-
The A-kinase anchoring domain of type IIalpha cAMP-dependent protein kinase is highly helical
-
Newlon MG, Roy M, Hausken ZE, Scott JD, Jennings PA (1997) The A-kinase anchoring domain of type IIalpha cAMP-dependent protein kinase is highly helical. J Biol Chem 272: 23637-23644
-
(1997)
J Biol Chem
, vol.272
, pp. 23637-23644
-
-
Newlon, M.G.1
Roy, M.2
Hausken, Z.E.3
Scott, J.D.4
Jennings, P.A.5
-
48
-
-
0035794551
-
A novel mechanism of PKA anchoring revealed by solution structures of anchoring complexes
-
Newlon MG, Roy M, Morikis D, Carr DW, Westphal R, Scott JD, Jennings PA (2001) A novel mechanism of PKA anchoring revealed by solution structures of anchoring complexes. EMBO J 20: 1651-1662
-
(2001)
EMBO J
, vol.20
, pp. 1651-1662
-
-
Newlon, M.G.1
Roy, M.2
Morikis, D.3
Carr, D.W.4
Westphal, R.5
Scott, J.D.6
Jennings, P.A.7
-
49
-
-
84867853849
-
Mitochondrial defect drives non-autonomous tumour progression through Hippo signalling in Drosophila
-
Ohsawa S, Sato Y, Enomoto M, Nakamura M, Betsumiya A, Igaki T (2012) Mitochondrial defect drives non-autonomous tumour progression through Hippo signalling in Drosophila. Nature 490: 547-551
-
(2012)
Nature
, vol.490
, pp. 547-551
-
-
Ohsawa, S.1
Sato, Y.2
Enomoto, M.3
Nakamura, M.4
Betsumiya, A.5
Igaki, T.6
-
50
-
-
0026590175
-
Mutations in the catalytic subunit of camp-dependent protein-kinase result in unregulated biological-activity
-
Orellana SA, Mcknight GS (1992) Mutations in the catalytic subunit of camp-dependent protein-kinase result in unregulated biological-activity. Proc Natl Acad Sci USA 89: 4726-4730
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 4726-4730
-
-
Orellana, S.A.1
McKnight, G.S.2
-
51
-
-
33747591465
-
Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon
-
Overholtzer M, Zhang J, Smolen GA, Muir B, Li W, Sgroi DC, Deng CX, Brugge JS, Haber DA (2006) Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon. Proc Natl Acad Sci USA 103: 12405-12410
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 12405-12410
-
-
Overholtzer, M.1
Zhang, J.2
Smolen, G.A.3
Muir, B.4
Li, W.5
Sgroi, D.C.6
Deng, C.X.7
Brugge, J.S.8
Haber, D.A.9
-
52
-
-
77957883342
-
The Hippo signaling pathway in development and cancer
-
Pan DJ (2010) The Hippo signaling pathway in development and cancer. Dev Cell 19: 491-505
-
(2010)
Dev Cell
, vol.19
, pp. 491-505
-
-
Pan, D.J.1
-
53
-
-
80053363788
-
Angiomotin family proteins are novel activators of the LATS2 kinase tumor suppressor
-
Paramasivam M, Sarkeshik A, Yates 3rd JR, Fernandes MJ, McCollum D (2011) Angiomotin family proteins are novel activators of the LATS2 kinase tumor suppressor. Mol Biol Cell 22: 3725-3733
-
(2011)
Mol Biol Cell
, vol.22
, pp. 3725-3733
-
-
Paramasivam, M.1
Sarkeshik, A.2
Yates III, J.R.3
Fernandes, M.J.4
McCollum, D.5
-
54
-
-
79958851169
-
Modulating F-actin organization induces organ growth by affecting the Hippo pathway
-
Sansores-Garcia L, Bossuyt W, Wada K, Yonemura S, Tao C, Sasaki H, Halder G (2011) Modulating F-actin organization induces organ growth by affecting the Hippo pathway. EMBO J 30: 2325-2335
-
(2011)
EMBO J
, vol.30
, pp. 2325-2335
-
-
Sansores-Garcia, L.1
Bossuyt, W.2
Wada, K.3
Yonemura, S.4
Tao, C.5
Sasaki, H.6
Halder, G.7
-
55
-
-
0032571272
-
Regulation of the neurofibromatosis type 2 tumor suppressor protein, Merlin, by adhesion and growth arrest stimuli
-
Shaw RJ, McClatchey AI, Jacks T (1998) Regulation of the neurofibromatosis type 2 tumor suppressor protein, Merlin, by adhesion and growth arrest stimuli. J Biol Chem 273: 7757-7764
-
(1998)
J Biol Chem
, vol.273
, pp. 7757-7764
-
-
Shaw, R.J.1
McClatchey, A.I.2
Jacks, T.3
-
57
-
-
20544465379
-
Rare amplicons implicate frequent deregulation of cell fate specification pathways in oral squamous cell carcinoma
-
Snijders AM, Schmidt BL, Fridlyand J, Dekker N, Pinkel D, Jordan RCK, Albertson DG (2005) Rare amplicons implicate frequent deregulation of cell fate specification pathways in oral squamous cell carcinoma. Oncogene 24: 4232-4242
-
(2005)
Oncogene
, vol.24
, pp. 4232-4242
-
-
Snijders, A.M.1
Schmidt, B.L.2
Fridlyand, J.3
Dekker, N.4
Pinkel, D.5
Rck, J.6
Albertson, D.G.7
-
58
-
-
76549127712
-
Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression
-
Song H, Mak KK, Topol L, Yun K, Hu J, Garrett L, Chen Y, Park O, Chang J, Simpson RM, Wang CY, Gao B, Jiang J, Yang Y (2010) Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression. Proc Natl Acad Sci USA 107: 1431-1436
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 1431-1436
-
-
Song, H.1
Mak, K.K.2
Topol, L.3
Yun, K.4
Hu, J.5
Garrett, L.6
Chen, Y.7
Park, O.8
Chang, J.9
Simpson, R.M.10
Wang, C.Y.11
Gao, B.12
Jiang, J.13
Yang, Y.14
-
59
-
-
77956507262
-
Warts and yorkie mediate intestinal regeneration by influencing stem cell proliferation
-
Staley BK, Irvine KD (2010) Warts and yorkie mediate intestinal regeneration by influencing stem cell proliferation. Curr Biol 20: 1580-1587
-
(2010)
Curr Biol
, vol.20
, pp. 1580-1587
-
-
Staley, B.K.1
Irvine, K.D.2
-
60
-
-
78049290801
-
Modularity in the Hippo signaling pathway
-
Sudol M, Harvey KF (2010) Modularity in the Hippo signaling pathway. Trends Biochem Sci 35: 627-633
-
(2010)
Trends Biochem Sci
, vol.35
, pp. 627-633
-
-
Sudol, M.1
Harvey, K.F.2
-
61
-
-
0035143541
-
PACAP is an anti-mitogenic signal in developing cerebral cortex
-
Suh JH, Lu NR, Nicot A, Tatsuno I, DiCicco-Bloom E (2001) PACAP is an anti-mitogenic signal in developing cerebral cortex. Nat Neurosci 4: 123-124
-
(2001)
Nat Neurosci
, vol.4
, pp. 123-124
-
-
Suh, J.H.1
Lu, N.R.2
Nicot, A.3
Tatsuno, I.4
Dicicco-Bloom, E.5
-
62
-
-
0037178783
-
LIM factor Lhx3 contributes to the specification of motor neuron and interneuron identity through cell-type-specific protein-protein interactions
-
Thaler JP, Lee SK, Jurata LW, Gill GN, Pfaff SL (2002) LIM factor Lhx3 contributes to the specification of motor neuron and interneuron identity through cell-type-specific protein-protein interactions. Cell 110: 237-249
-
(2002)
Cell
, vol.110
, pp. 237-249
-
-
Thaler, J.P.1
Lee, S.K.2
Jurata, L.W.3
Gill, G.N.4
Pfaff, S.L.5
-
63
-
-
0037205044
-
Signaling pathways for PC12 cell differentiation: Making the right connections
-
Vaudry D, Stork PJS, Lazarovici P, Eiden LE (2002) Signaling pathways for PC12 cell differentiation: making the right connections. Science 296: 1648-1649
-
(2002)
Science
, vol.296
, pp. 1648-1649
-
-
Vaudry, D.1
Pjs, S.2
Lazarovici, P.3
Eiden, L.E.4
-
64
-
-
80051923057
-
Hippo pathway regulation by cell morphology and stress fibers
-
Wada KI, Itoga K, Okano T, Yonemura S, Sasaki H (2011) Hippo pathway regulation by cell morphology and stress fibers. Development 138: 3907-3914
-
(2011)
Development
, vol.138
, pp. 3907-3914
-
-
Wada, K.I.1
Itoga, K.2
Okano, T.3
Yonemura, S.4
Sasaki, H.5
-
65
-
-
79953010044
-
Angiomotin-like proteins associate with and negatively regulate YAP1
-
Wang W, Huang J, Chen J (2011) Angiomotin-like proteins associate with and negatively regulate YAP1. J Biol Chem 286: 4364-4370
-
(2011)
J Biol Chem
, vol.286
, pp. 4364-4370
-
-
Wang, W.1
Huang, J.2
Chen, J.3
-
66
-
-
0025249229
-
Direct stimulation of adenylate cyclase by mechanical forces in S49 mouse lymphoma cells during hyposmotic swelling
-
Watson PA (1990) Direct stimulation of adenylate cyclase by mechanical forces in S49 mouse lymphoma cells during hyposmotic swelling. J Biol Chem 265: 6569-6575
-
(1990)
J Biol Chem
, vol.265
, pp. 6569-6575
-
-
Watson, P.A.1
-
67
-
-
0030034263
-
Clinically distinct subgroups of glioblastoma multiforme studied by comparative genomic hybridization
-
Weber RG, Sommer C, Albert FK, Kiessling M, Cremer T (1996) Clinically distinct subgroups of glioblastoma multiforme studied by comparative genomic hybridization. Lab Invest 74: 108-119
-
(1996)
Lab Invest
, vol.74
, pp. 108-119
-
-
Weber, R.G.1
Sommer, C.2
Albert, F.K.3
Kiessling, M.4
Cremer, T.5
-
68
-
-
10044253425
-
AKAP signalling complexes: Focal points in space and time
-
WongW, Scott JD (2004) AKAP signalling complexes: focal points in space and time. Nat Rev Mol Cell Biol 5: 959-970
-
(2004)
Nat Rev Mol Cell Biol
, vol.5
, pp. 959-970
-
-
Wong, W.1
Scott, J.D.2
-
69
-
-
79953753962
-
A tight junction-associated merlinangiomotin complex mediates merlin's regulation of mitogenic signaling and tumor suppressive functions
-
Yi CL, Troutman S, Fera D, Stemmer-Rachamimov A, Avila JL, Christian N, Persson NL, Shimono A, Speicher DW, Marmorstein R, Holmgren L, Kissil JL (2011) A tight junction-associated merlinangiomotin complex mediates merlin's regulation of mitogenic signaling and tumor suppressive functions. Cancer Cell 19: 527-540
-
(2011)
Cancer Cell
, vol.19
, pp. 527-540
-
-
Yi, C.L.1
Troutman, S.2
Fera, D.3
Stemmer-Rachamimov, A.4
Avila, J.L.5
Christian, N.6
Persson, N.L.7
Shimono, A.8
Speicher, D.W.9
Marmorstein, R.10
Holmgren, L.11
Kissil, J.L.12
-
70
-
-
84865260845
-
Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling
-
Yu FX, Zhao B, Panupinthu N, Jewell JL, Lian I, Wang LH, Zhao J, Yuan H, Tumaneng K, Li H, Fu XD, Mills GB, Guan KL (2012) Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling. Cell 150: 780-791
-
(2012)
Cell
, vol.150
, pp. 780-791
-
-
Yu, F.X.1
Zhao, B.2
Panupinthu, N.3
Jewell, J.L.4
Lian, I.5
Wang, L.H.6
Zhao, J.7
Yuan, H.8
Tumaneng, K.9
Li, H.10
Fu, X.D.11
Mills, G.B.12
Guan, K.L.13
-
71
-
-
76249109900
-
Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded
-
Yu J, Zheng Y, Dong J, Klusza S, Deng WM, Pan D (2010) Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded. Dev Cell 18: 288-299
-
(2010)
Dev Cell
, vol.18
, pp. 288-299
-
-
Yu, J.1
Zheng, Y.2
Dong, J.3
Klusza, S.4
Deng, W.M.5
Pan, D.6
-
72
-
-
83055184190
-
Negative regulation of Yap during neuronal differentiation
-
Zhang HQ, Deo M, Thompson RC, Uhler MD, Turner DL (2012) Negative regulation of Yap during neuronal differentiation. Dev Biol 361: 103-115
-
(2012)
Dev Biol
, vol.361
, pp. 103-115
-
-
Zhang, H.Q.1
Deo, M.2
Thompson, R.C.3
Uhler, M.D.4
Turner, D.L.5
-
73
-
-
84878621733
-
YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway. Nat Cell Biol 11: 1444-U1134 Zhao B, Kim J, Ye X, Lai ZC, Guan KL
-
Zhang JM, Ji JY, Yu M, Overholtzer M, Smolen GA, Wang R, Brugge JS, Dyson NJ, Haber DA (2009) YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway. Nat Cell Biol 11: 1444-U1134 Zhao B, Kim J, Ye X, Lai ZC, Guan KL (2009) Both TEAD-binding and WW domains are required for the growth stimulation and oncogenic transformation activity of Yes-associated protein. Cancer Res 69: 1089-1098
-
(2009)
Both TEAD-binding and WW Domains Are Required for the Growth Stimulation and Oncogenic Transformation Activity of Yes-associated Protein. Cancer Res
, vol.69
, pp. 1089-1098
-
-
Zhang, J.M.1
Ji, J.Y.2
Yu, M.3
Overholtzer, M.4
Smolen, G.A.5
Wang, R.6
Brugge, J.S.7
Dyson, N.J.8
Haber, D.A.9
-
74
-
-
77951837150
-
The Hippo-YAP pathway in organ size control and tumorigenesis: An updated version
-
Zhao B, Li L, Lei Q, Guan KL (2010a) The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version. Genes Dev 24: 862-874
-
(2010)
Genes Dev
, vol.24
, pp. 862-874
-
-
Zhao, B.1
Li, L.2
Lei, Q.3
Guan, K.L.4
-
75
-
-
78650895035
-
Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein
-
Zhao B, Li L, Lu Q, Wang LH, Liu CY, Lei QY, Guan KL (2011) Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein. Gene Dev 25: 51-63
-
(2011)
Gene Dev
, vol.25
, pp. 51-63
-
-
Zhao, B.1
Li, L.2
Lu, Q.3
Wang, L.H.4
Liu, C.Y.5
Lei, Q.Y.6
Guan, K.L.7
-
76
-
-
73549095761
-
A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)
-
Zhao B, Li L, Tumaneng K, Wang CY, Guan KL (2010b) A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP). Genes Dev 24: 72-85
-
(2010)
Genes Dev
, vol.24
, pp. 72-85
-
-
Zhao, B.1
Li, L.2
Tumaneng, K.3
Wang, C.Y.4
Guan, K.L.5
-
77
-
-
84855326431
-
Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis
-
Zhao B, Li L, Wang L, Wang CY, Yu J, Guan KL (2012) Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis. Genes Dev 26: 54-68
-
(2012)
Genes Dev
, vol.26
, pp. 54-68
-
-
Zhao, B.1
Li, L.2
Wang, L.3
Wang, C.Y.4
Yu, J.5
Guan, K.L.6
-
78
-
-
35948961118
-
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control
-
Zhao B,Wei X, LiW, Udan RS, Yang Q, Kim J, Xie J, Ikenoue T, Yu J, Li L, Zheng P, Ye K, Chinnaiyan A, Halder G, Lai ZC, Guan KL (2007) Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control. Genes Dev 21: 2747-2761
-
(2007)
Genes Dev
, vol.21
, pp. 2747-2761
-
-
Zhao, B.1
Wei, X.2
Li, W.3
Udan, R.S.4
Yang, Q.5
Kim, J.6
Xie, J.7
Ikenoue, T.8
Yu, J.9
Li, L.10
Zheng, P.11
Ye, K.12
Chinnaiyan, A.13
Halder, G.14
Lai, Z.C.15
Guan, K.L.16
-
79
-
-
70350502865
-
Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene
-
Zhou D, Conrad C, Xia F, Park JS, Payer B, Yin Y, Lauwers GY, Thasler W, Lee JT, Avruch J, Bardeesy N (2009) Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene. Cancer Cell 16: 425-438
-
(2009)
Cancer Cell
, vol.16
, pp. 425-438
-
-
Zhou, D.1
Conrad, C.2
Xia, F.3
Park, J.S.4
Payer, B.5
Yin, Y.6
Lauwers, G.Y.7
Thasler, W.8
Lee, J.T.9
Avruch, J.10
Bardeesy, N.11
-
80
-
-
83755195660
-
Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance
-
Zhou D, Zhang Y, Wu H, Barry E, Yin Y, Lawrence E, Dawson D, Willis JE, Markowitz SD, Camargo FD, Avruch J (2011) Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance. Proc Natl Acad Sci USA 108: E1312-E1320
-
(2011)
Proc Natl Acad Sci USA
, vol.108
-
-
Zhou, D.1
Zhang, Y.2
Wu, H.3
Barry, E.4
Yin, Y.5
Lawrence, E.6
Dawson, D.7
Willis, J.E.8
Markowitz, S.D.9
Camargo, F.D.10
Avruch, J.11
|