Natural killer cell heterogeneity: Cellular dysfunction and significance in HIV-1 immuno-pathogenesis

Cellular and Molecular Life Sciences

Volumn 72, Issue 16, 2015, Pages 3037-3049

  Ansari, A Wahid ^a,b   Ahmad, Fareed ^a   Meyer Olson, Dirk ^a   Kamarulzaman, Adeeba ^b   Jacobs, Roland ^a   Schmidt, Reinhold E ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b UNIVERSITY OF MALAYA   (Malaysia)

Author keywords

Antibody dependent cellular cytotoxicity; CD56 dim and bright; Granzyme B; Highly active antiretroviral therapy; Innate immunity

Indexed keywords

ANTIRETROVIRUS AGENT; CD161 ANTIGEN; CD56 ANTIGEN; CD94 ANTIGEN; HLA ANTIGEN; INTERFERON; INTERLEUKIN 12; INTERLEUKIN 15; INTERLEUKIN 2; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 1; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 2; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 3; NATURAL KILLER CELL RECEPTOR NKG2D; VPU PROTEIN; LECTIN; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADAPTIVE IMMUNITY; ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY; ANTIGEN BINDING; ANTIVIRAL ACTIVITY; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DAMAGE; CELL DIFFERENTIATION; CELL HETEROGENEITY; CELL PHAGOCYTOSIS; COMORBIDITY; CYTOKINE RELEASE; DENDRITIC CELL; DISEASE COURSE; HANTA VIRUS; HEPATITIS B VIRUS; HEPATITIS C VIRUS; HIGH RISK PATIENT; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN CYTOMEGALOVIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMORAL IMMUNITY; IMMUNE EVASION; IMMUNOPATHOGENESIS; INFECTION CONTROL; INNATE IMMUNITY; LYMPHOCYTE SUBPOPULATION; MORBIDITY; MORTALITY; NATURAL KILLER CELL; NONHUMAN; PROGNOSIS; PROTEIN FUNCTION; REVIEW; VIREMIA; VIRUS; VIRUS REPLICATION; CYTOLOGY; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOLOGY; METABOLISM; PATHOPHYSIOLOGY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

HIV INFECTIONS; HIV-1; HLA ANTIGENS; HUMANS; IMMUNITY, INNATE; KILLER CELLS, NATURAL; LECTINS, C-TYPE; RECEPTORS, KIR; RECEPTORS, NATURAL CYTOTOXICITY TRIGGERING;

EID: 84937974362     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-015-1911-5     Document Type: Review

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