Critical role for the chemokine receptor CXCR6 in NK cell-mediated antigen-specific memory of haptens and viruses

Nature Immunology

Volumn 11, Issue 12, 2010, Pages 1127-1135

  Paust, Silke ^a,b   Gill, Harvinder S ^c,d   Wang, Bao Zhong ^c   Flynn, Michael P ^a   Moseman, E Ashley ^a   Senman, Balimkiz ^a   Szczepanik, Marian ^e,g   Telenti, Amalio ^b,f   Askenase, Philip W ^g   Compans, Richard W ^c   Von Andrian, Ulrich H ^a,h  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Department of Electrical and Computer Engineering   (United States)

^e JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^f LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^g YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^h CENTER FOR BLOOD RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR6; HAPTEN; HUMAN IMMUNODEFICIENCY VIRUS ANTIGEN; VIRUS ANTIGEN;

ADOPTIVE TRANSFER; ANTIGEN RECOGNITION; ANTIGEN SPECIFICITY; ARTICLE; CONTROLLED STUDY; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNOLOGICAL MEMORY; INFLUENZA VIRUS; LIVER CELL; MEMORY CELL; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROVOCATION TEST; RECIPIENT; VESICULAR STOMATITIS VIRUS;

ADAPTIVE IMMUNITY; ADOPTIVE TRANSFER; ANIMALS; CELL SEPARATION; CHEMOTAXIS, LEUKOCYTE; CYTOTOXICITY, IMMUNOLOGIC; FLOW CYTOMETRY; HAPTENS; IMMUNOLOGIC MEMORY; KILLER CELLS, NATURAL; LIVER; LYMPHOCYTE SUBSETS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; RECEPTORS, CXCR; VIRUS DISEASES; VIRUSES;

EID: 78449275107     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.1953     Document Type: Article

References (45)

1. Bassing, C.H., Swat, W. & Alt, F.W. The mechanism and regulation of chromosomal V(D)J recombination. Cell 109 Suppl, S45-S55 (2002)
2. Crowle, A.J. Delayed hypersensitivity in mice; its detection by skin tests and its passive transfer. Science 130, 159-160 (1959)
3. Orme, I.M. & Cooper, A.M. Cytokine/chemokine cascades in immunity to tuberculosis. Immunol. Today 20, 307-312 (1999)
4. Dhabhar, F.S., Satoskar, A.R., Bluethmann, H., David, J.R. & McEwen, B.S. Stress-induced enhancement of skin immune function: A role for γ interferon. Proc. Natl. Acad. Sci. USA 97, 2846-2851 (2000)
5. Phanuphak, P., Moorhead, J.W. & Claman, H.N. Tolerance and contact sensitivity to DNFB in mice. II. Specifc in vitro stimulation with a hapten, 2,4-dinitrobenzene sulfonic acid (DNB-SO3Na). J. Immunol. 112, 849-851 (1974)
6. Lanier, L.L. Up on the tightrope: natural killer cell activation and inhibition. Nat. Immunol. 9, 495-502 (2008)
7. Lanier, L.L. NK cell recognition. Annu. Rev. Immunol. 23, 225-274 (2005)
8. Mandelboim, O. et al. Recognition of haemagglutinins on virus-infected cells by NKp46 activates lysis by human NK cells. Nature 409, 1055-1060 (2001)
9. Gazit, R. et al. Lethal infuenza infection in the absence of the natural killer cell receptor gene Ncr1. Nat. Immunol. 7, 517-523 (2006)
10. Smith, H.R. et al. Recognition of a virus-encoded ligand by a natural killer cell activation receptor. Proc. Natl. Acad. Sci. USA 99, 8826-8831 (2002)
11. Kim, S. et al. Licensing of natural killer cells by host major histocompatibility complex class I molecules. Nature 436, 709-713 (2005)
12. Jonsson, A.H. & Yokoyama, W.M. Natural killer cell tolerance licensing and other mechanisms. Adv. Immunol. 101, 27-79 (2009)
13. Sun, J.C., Beilke, J.N. & Lanier, L.L. Adaptive immune features of natural killer cells. Nature 457, 557-561 (2009)
14. Scalzo, A.A., Manzur, M., Forbes, C.A., Brown, M.G. & Shellam, G.R. NK gene complex haplotype variability and host resistance alleles to murine cytomegalovirus in wild mouse populations. Immunol. Cell Biol. 83, 144-149 (2005)
15. Martin, M.P. et al. Epistatic interaction between KIR3DS1 and HLA-B delays the progression to AIDS. Nat. Genet. 31, 429-434 (2002)
16. Alter, G. et al. Differential natural killer cell-mediated inhibition of HIV-1 replication based on distinct KIR/HLA subtypes. J. Exp. Med. 204, 3027-3036 (2007)
17. O'Leary, J.G., Goodarzi, M., Drayton, D.L. & von Andrian, U.H. T cell- and B cell-independent adaptive immunity mediated by natural killer cells. Nat. Immunol. 7, 507-516 (2006)
18. Boehncke, W.H. et al. Leukocyte extravasation as a target for anti-infammatory therapy Which molecule to choose? Exp. Dermatol. 14, 70-80 (2005)
19. DiSanto, J.P., Muller, W., Guy-Grand, D., Fischer, A. & Rajewsky, K. Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor γ chain. Proc. Natl. Acad. Sci. USA 92, 377-381 (1995)
20. Paust, S., Senman, B. & von Andrian, U.H. Adaptive immune responses mediated by natural killer cells. Immunol. Rev. 235, 286-296 (2010)
21. Matangkasombut, P. et al. Lack of iNKT cells in patients with combined immune defciency due to hypomorphic RAG mutations. Blood 111, 271-274 (2008)
22. + NKT cells patrolling liver sinusoids. PLoS Biol. 3, e113 (2005)
23. Day, C.E. et al. A novel method for isolation of human lung T cells from lung resection tissue reveals increased expression of GAPDH and CXCR6. J. Immunol. Methods 342, 91-97 (2009)
24. Matloubian, M., David, A., Engel, S., Ryan, J.E. & Cyster, J.G. A transmembrane CXC chemokine is a ligand for HIV-coreceptor Bonzo. Nat. Immunol. 1, 298-304 (2000)
25. + cells. J. Leukoc. Biol. 87, 1029-1039 (2010)
26. + lymphocytes to infamed liver. J. Immunol. 174, 277-283 (2005)
27. Park, B.K., Tingle, M.D., Grabowski, P.S., Coleman, J.W. & Kitteringham, N.R. Drug-protein conjugates-XI. Disposition and immunogenicity of dinitrofuorobenzene, a model compound for the investigation of drugs as haptens. Biochem. Pharmacol. 36, 591-599 (1987)
28. Di Santo, J.P., Colucci, F. & Guy-Grand, D. Natural killer and T cells of innate and adaptive immunity: lymphoid compartments with different requirements for common gamma chain-dependent cytokines. Immunol. Rev. 165, 29-38 (1998)
29. Jamieson, A.M., Isnard, P., Dorfman, J.R., Coles, M.C. & Raulet, D.H. Turnover and proliferation of NK cells in steady state and lymphopenic conditions. J. Immunol. 172, 864-870 (2004)
30. Quan, F.S., Huang, C., Compans, R.W. & Kang, S.M. Virus-like particle vaccine induces protective immunity against homologous and heterologous strains of infuenza virus. J. Virol. 81, 3514-3524 (2007)
31. Kang, S.M., Song, J.M., Quan, F.S. & Compans, R.W. Infuenza vaccines based on virus-like particles. Virus Res. 143, 140-146 (2009)
32. Hangartner, L., Zinkernagel, R.M. & Hengartner, H. Antiviral antibody responses: the two extremes of a wide spectrum. Nat. Rev. Immunol. 6, 231-243 (2006)
33. Draghi, M. et al. NKp46 and NKG2D recognition of infected dendritic cells is necessary for NK cell activation in the human response to infuenza infection. J. Immunol. 178, 2688-2698 (2007)
34. Wang, B.Z. et al. Incorporation of high levels of chimeric human immunodefciency virus envelope glycoproteins into virus-like particles. J. Virol. 81, 10869-10878 (2007)
35. Shultz, L.D. et al. NOD/LtSz-Rag1null mice: an immunodefcient and radioresistant model for engraftment of human hematolymphoid cells, HIV infection, and adoptive transfer of NOD mouse diabetogenic T cells. J. Immunol. 164, 2496-2507 (2000)
36. Wilbanks, A. et al. Expression cloning of the STRL33/BONZO/TYMSTR ligand reveals elements of CC, CXC, and CX3C chemokines. J. Immunol. 166, 5145-5154 (2001)
37. Szczepanik, M. et al. B-1 B cells mediate required early T cell recruitment to elicit protein-induced delayed-type hypersensitivity. J. Immunol. 171, 6225-6235 (2003)
38. Aktas, E., Kucuksezer, U.C., Bilgic, S., Erten, G. & Deniz, G. Relationship between CD107a expression and cytotoxic activity. Cell. Immunol. 254, 149-154 (2009)
39. Raulet, D.H. A sense of something missing. Nature 358, 21-22 (1992)
40. - NK cells accumulate in allergic contact dermatitis and contribute to the expression of allergic responses. J. Immunol. 184, 1102-1110 (2010)
41. Scholz, F. et al. Constitutive expression and regulated release of the transmembrane chemokine CXCL16 in human and murine skin. J. Invest. Dermatol. 127, 1444-1455 (2007)
42. Martin, M.P. et al. Innate partnership of HLA-B and KIR3DL1 subtypes against HIV-1. Nat. Genet. 39, 733-740 (2007)
43. Limou, S. et al. Multiple-cohort genetic association study reveals CXCR6 as a new chemokine receptor involved in long-term nonprogression to AIDS. J. Infect. Dis. 202, 908-915 (2010)
44. Berahovich, R.D., Lai, N.L., Wei, Z., Lanier, L.L. & Schall, T.J. Evidence for NK cell subsets based on chemokine receptor expression. J. Immunol. 177, 7833-7840 (2006)
45. Cao, X. et al. Defective lymphoid development in mice lacking expression of the common cytokine receptor γ chain. Immunity 2, 223-238 (1995