HLA-Cw*0102-restricted HIV-1 p24 epitope variants can modulate the binding of the inhibitory KIR2DL2 receptor and primary NK cell function

PLoS Pathogens

Volumn 8, Issue 7, 2012, Pages 40-

  Fadda, Lena ^a   Körner, Christian ^a   Kumar, Swati ^a   van Teijlingen, Nienke H ^a   Piechocka Trocha, Alicja ^a   Carrington, Mary ^a,b   Altfeld, Marcus ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b SAIC FREDERICK INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAG PROTEIN; HLA C ANTIGEN; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DL2; HLA C*01:02 ANTIGEN; HLA-C*01:02 ANTIGEN; KIR2DL2 PROTEIN, HUMAN;

ANTIGEN EXPRESSION; ARTICLE; CELL FUNCTION; CONTROLLED STUDY; DEGRANULATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; NATURAL KILLER CELL; NONHUMAN; PROTEIN BINDING; PROTEIN EXPRESSION; RECEPTOR BINDING; SEQUENCE ANALYSIS; CELL LINE; CYTOTOXICITY; GENETIC VARIABILITY; GENETICS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE EVASION; IMMUNOLOGY; METABOLISM; SEQUENCE ALIGNMENT;

HUMAN IMMUNODEFICIENCY VIRUS 1;

CELL LINE; CYTOTOXICITY, IMMUNOLOGIC; GENETIC VARIATION; HIV CORE PROTEIN P24; HIV INFECTIONS; HIV-1; HLA-C ANTIGENS; HUMANS; IMMUNE EVASION; KILLER CELLS, NATURAL; PROTEIN BINDING; RECEPTORS, KIR2DL2; SEQUENCE ALIGNMENT;

EID: 84864575731     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002805     Document Type: Article

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