Soluble ligands for the NKG2D receptor are released during HIV-1 infection and impair NKG2D expression and cytotoxicity of NK cells

FASEB Journal

Volumn 27, Issue 6, 2013, Pages 2440-2450

  Matusali, Giulia ^a   Tchidjou, Hyppolite Kuekou ^a   Pontrelli, Giuseppe ^a   Bernardi, Stefania ^a   D'Ettorre, Gabriella ^b   Vullo, Vincenzo ^b   Buonomini, Anna Rita ^c   Andreoni, Massimo ^c   Santoni, Angela ^b   Cerboni, Cristina ^b   Doria, Margherita ^a  

^a BAMBINO GESÙ CHILDREN S HOSPITAL   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

Immune evasion; MICA B; Shedding; ULBP

Indexed keywords

BINDING PROTEIN; LIGAND; MATRIX METALLOPROTEINASE INHIBITOR; NATURAL KILLER GROUP 2 MEMBER D RECEPTOR; RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL SURFACE; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HOST RESISTANCE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE EVASION; IMMUNOSURVEILLANCE; LEUKEMIA CELL LINE; MAJOR CLINICAL STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX; NATURAL KILLER CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

IMMUNE EVASION; MICA/B; SHEDDING; ULBP;

ADOLESCENT; ADULT; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; CASE-CONTROL STUDIES; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CYTOTOXICITY, IMMUNOLOGIC; GPI-LINKED PROTEINS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HIV INFECTIONS; HIV-1; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; JURKAT CELLS; K562 CELLS; KILLER CELLS, NATURAL; LIGANDS; MATRIX METALLOPROTEINASE 1; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY K; YOUNG ADULT;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 84878763877     PISSN: None     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.12-223057     Document Type: Article

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