Erratum: The Causative Gene in Chanarian Dorfman Syndrome Regulates Lipid Droplet Homeostasis in C. elegans (PLoS Genetics (2015) 11:6 (e1005284) DOI: 10.1371/journal.pgen.1005284);The Causative Gene in Chanarian Dorfman Syndrome Regulates Lipid Droplet Homeostasis in C. elegans

PLoS Genetics

Volumn 11, Issue 6, 2015, Pages

  Xie, Meng ^a   Roy, Richard ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

POLYUNSATURATED FATTY ACID; 1 ACYLGLYCEROPHOSPHATE ACYLTRANSFERASE; ATGL-1 PROTEIN, C ELEGANS; CAENORHABDITIS ELEGANS PROTEIN; FAT DROPLET; TRIACYLGLYCEROL LIPASE; UNSATURATED FATTY ACID;

ADULT; ANALYSIS OF VARIANCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLEACHING; CAENORHABDITIS ELEGANS; CHANARIAN DORFMAN SYNDROME; CONTROLLED STUDY; DISORDERS OF LIPID METABOLISM; ENZYME ACTIVITY; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; GENE FUNCTION; HOMEOSTASIS; HYDROLYSIS; IMMUNOPRECIPITATION; LIPID COMPOSITION; LIPID HOMEOSTASIS; LIPID STORAGE; MASS FRAGMENTOGRAPHY; MORPHOLOGY; NONHUMAN; OSMOREGULATION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN STABILITY; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; AMINO ACID SEQUENCE; ANIMAL; CONGENITAL ICHTHYOSIFORM ERYTHRODERMA; DISORDERS OF LIPID AND LIPOPROTEIN METABOLISM; GENETICS; METABOLISM; MOLECULAR GENETICS; MUSCLE DISEASE;

CAENORHABDITIS ELEGANS;

1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE; AMINO ACID SEQUENCE; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; FATTY ACIDS, UNSATURATED; HOMEOSTASIS; ICHTHYOSIFORM ERYTHRODERMA, CONGENITAL; LIPASE; LIPID DROPLETS; LIPID METABOLISM, INBORN ERRORS; MOLECULAR SEQUENCE DATA; MUSCULAR DISEASES;

EID: 84937781732     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/JOURNAL.PGEN.1006524     Document Type: Erratum

References (56)

1. Jonkel CJ, Jonkel McT, Cowan I, , (1977) The black bear in the spruce fir forest. Wildl. Monogr 27: 1–57.
2. Holliday R, , (1989) Food, reproduction and longevity: is the extended lifespan of calorie-restricted animals an evolutionary adaptation? Bioessays 10: 125–127. 2730632
3. Kirkwood TB, , (1977) Evolution of ageing. Nature 270: 301–304. 593350
4. Selesniemi K, Lee HJ, Tilly JL, , (2008) Moderate caloric restriction initiated in rodents during adulthood sustains function of the female reproductive axis into advanced chronological age. Aging Cell 7: 622–629. doi: 10.1111/j.1474-9726.2008.00409.x 18549458
5. Riddle DL, Georgi LL, , (1990) Advances in research on Caenorhabditis elegans: Application to plant parasitic nematodes. Annu Rev Phytopathol 28: 247–269. doi: 10.1146/annurev.py.28.090190.001335 25945519
6. Fielenbach N, Antebi A, , (2008) C. elegans dauer formation and the molecular basis of plasticity. Genes&Development 22: 2149–2165.
7. Narbonne P, Roy R, , (2006) Inhibition of germline proliferation during C. elegans dauer development requires PTEN, LKB1 and AMPK signaling. Development 133: 611–619. 16407400
8. Hawley SA, Boudeau J, Reid JL, Mustard KJ, Udd L, et al. (2003) Complexes between the LKB1 tumor suppressor, STRADa/b and MO25a/b are upstream kinases in the AMP-activated protein kinase cascade. J. Biol 2: 28. 14511394
9. Woods A, Johnstone SR, Dickerson K, Leiper FC, Fryer LG, et al. (2003) LKB1 is the upstream kinase in the AMP-activated protein kinase cascade. Curr. Biol 13: 2004–2008. 14614828
10. Hardie DG, , (2007) AMP-activated /SNF1 protein kinases: Conserved guardians of cellular energy. Nature Rev. Mol. Cell Biol 8: 774–785. 17712357
11. Haemmerle G, Lass A, Zimmermann R, Gorkiewicz G, Meyer C, et al. (2006) Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase. Science 312: 734–737. 16675698
12. Lefèvre C, Jobard F, Caux F, Bouadjar B, Karaduman A, et al. (2001) Mutations in CGI-58, the gene encoding a new protein of the esterase/lipase/thioesterase subfamily, in Chanarin-Dorfman syndrome. Am J Hum Genet 69: 1002–1012. 11590543
13. Lass A, Zimmermann R, Haemmerle G, Riederer M, Schoiswohl G, et al. (2006) Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome. Cell Metab 3: 309–319. 16679289
14. Eichmann TO, Kumari M, Haas JT, Farese RV, JrZimmermann R, et al. (2012) Studies on the substrate and stereo/regioselectivity of adipose triglyceride lipase, hormone-sensitive lipase, and diacylglycerol-O-acyltransferases. J Biol Chem. 287: 41446–41457. doi: 10.1074/jbc.M112.400416 23066022
15. Gruber A, Cornaciu I, Lass A, Schweiger M, Poeschl M, et al. (2010) The N-terminal region of comparative gene identification-58 (CGI-58) is important for lipid droplet binding and activation of adipose triglyceride lipase. J Biol Chem 285: 12289–12298. doi: 10.1074/jbc.M109.064469 20164531
16. Narbonne P, Roy R, , (2009) Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival. Nature 457: 210–214. doi: 10.1038/nature07536 19052547
17. Xie M, Roy R, , (2012) Increased levels of hydrogen peroxide induce a HIF-1-dependent modification of lipid metabolism in AMPK compromised C. elegans dauer larvae. Cell Metab 16: 322–335. doi: 10.1016/j.cmet.2012.07.016 22921415
18. Yang X, Lu X, Lombès M, Rha GB, Chi YI, et al. (2010) The G(0)/G(1) switch gene 2 regulates adipose lipolysis through association with adipose triglyceride lipase. Cell Metab 11: 194–205. doi: 10.1016/j.cmet.2010.02.003 20197052
19. Lee JH, Kong J, Jang JY, Han JS, Ji Y, et al. (2014) Lipid droplet protein LID-1 mediates ATGL-1-dependent lipolysis during fasting in Caenorhabditis elegans. Mol Cell Biol 34: 4165–4176. doi: 10.1128/MCB.00722-14 25202121
20. Schweiger M, Schoiswohl G, Lass A, Radner FP, Haemmerle G, et al. (2008) The C-terminal region of human adipose triglyceride lipase affects enzyme activity and lipid droplet binding. J Biol Chem 283: 17211–17220. doi: 10.1074/jbc.M710566200 18445597
21. Zhang SO, Trimble R, Guo F, Mak HY, , (2010) Lipid droplets as ubiquitous fat storage organelles in C. elegans. BMC Cell Biology 11: 96. doi: 10.1186/1471-2121-11-96 21143850
22. Walther TC, Farese RV, JrLipid droplets and cellular lipid metabolism. Annu Rev Biochem. 81: 687–714. doi: 10.1146/annurev-biochem-061009-102430 22524315
23. Watts JL, Browse J, , (2002) Genetic dissection of polyunsaturated fatty acid synthesis in Caenorhabditis elegans. PNAS 99: 5854–5859. 11972048
24. Thiam AR, Farese RV, JrWalther TC, , (2013) The biophysics and cell biology of lipid droplets. Nat Rev Mol Cell Biol 14: 775–786. doi: 10.1038/nrm3699 24220094
25. Ghosh AK, Ramakrishnan G, Chandramohan C, Rajasekharan R, , (2008) CGI-58, the causative gene for Chanarin-Dorfman syndrome, mediates acylation of lysophosphatidic acid. J Biol Chem 283: 24525–24533. doi: 10.1074/jbc.M801783200 18606822
26. Montero-Moran G, Caviglia JM, McMahon D, Rothenberg A, Subramanian V, et al. (2008) CGI-58/ABHD5 is a coenzyme A-dependent lysophosphatidic acid acyltransferase. J Lipid Res 51: 709–719.
27. McMahon D, Dinh A, Kurz D, Shah D, Han GS, et al. (2014) Comparative gene identification 58/α/β hydrolase domain 5 lacks lysophosphatidic acid acyltransferase activity. J Lipid Res 55: 1750–1761. 24879803
28. Delon C, Manifava M, Wood E, Thompson D, Krugmann S, et al. (2004) Sphingosine kinase 1 is an intracellular effector of phosphatidic acid. J Biol Chem 279: 44763–44774. 15310762
29. Moritz A, De Graan PN, Gispen WH, Wirtz KW, , (1992) Phosphatidic acid is a specific activator of phosphatidylinositol-4-phosphate kinase. J Biol Chem 267: 7207–7210. 1313792
30. Golden A, Liu J, Cohen-Fix O, , (2009) Inactivation of the C. elegans lipin homolog leads to ER disorganization and to defects in the breakdown and reassembly of the nuclear envelope. J Cell Sci 122: 1970–1978. doi: 10.1242/jcs.044743 19494126
31. Ohba Y, Sakuragi T, Kage-Nakadai E, Tomioka NH, Kono N, et al. (2013) Mitochondria-type GPAT is required for mitochondrial fusion. EMBO J 32: 1265–1279. doi: 10.1038/emboj.2013.77 23572076
32. Riddle DL, Albert PS, elegans C, IIRiddle D.L., , (1997) Genetic and environmental regulation of Dauer larva development. in et al. editors Cold Spring Harbor Laboratory Press, pp739–768.
33. Perez CL, Van Gilst MR, , (2008) A 13C isotope labeling strategy reveals the influence of insulin signaling on lipogenesis in C. elegans. Cell Metab 8: 266–274. doi: 10.1016/j.cmet.2008.08.007 18762027
34. Apfeld J, O’Connor G, McDonagh T, DiStefano PS, Curtis R, , (2004) The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans. Genes Dev 18: 3004–3009. 15574588
35. Curtis R, O’Connor G, DiStefano PS, , (2006) Aging networks in Caenorhabditis elegans: AMP-activated protein kinase (aak-2) links multiple aging and metabolism pathways. Aging Cell 5: 119–126. 16626391
36. Cunninghak KA, Bouagnon AD, Barros AG, Lin L, Malard L, et al. (2014) Loss of a neural AMP-activated kinase mimics the effects of elevated serotonin on fat, movement, and hormonal secretions. PLoS Genet 10: e1004394. doi: 10.1371/journal.pgen.1004394 24921650
37. Brasaemle DL, , (2007) Thematic review series: adipocyte biology. The Perilipin family of structural lipid droplet proteins: stabilization of lipid droplets and control of lipolysis. J Lipid Res 48: 2547–2559. 17878492
38. Puri V, Ranjit S, Konda S, Nicoloro SM, Straubhaar J, et al. (2008) Cidea is associated with lipid droplets and insulin sensitivity in humans. PNAS 105: 7833–7838. doi: 10.1073/pnas.0802063105 18509062
39. Boström P, Andersson L, Rutberg M, Perman J, Lidberg U, et al. (2007) SNARE proteins mediate fusion between cytosolic lipid droplets and are implicated in insulin sensitivity. Nat Cell Biol. 9:1286–1293. 17922004
40. Guo Y, Walther TC, Rao M, Stuurman N, Goshima G, et al. (2008) Functional genomic screen reveals genes involved in lipid-droplet formation and utilization. Nature 453: 657–661. doi: 10.1038/nature06928 18408709
41. Siloto RM, Findlay K, Lopez-Villalobos A, Yeung EC, Nykiforuk CL, et al. (2006) The accumulation of oleosins determines the size of seed oil bodies in Arabidopsis. Plant Cell 18: 1961–1974. 16877495
42. Farese RV, JrWalther TC, , (2009) Lipid droplets finally get a little R-E-S-P-E-C-T. Cell 139: 855–860. doi: 10.1016/j.cell.2009.11.005 19945371
43. Miyoshi H, Perfield JW, 2ndSouza SC, Shen WJ, Zhang HH, et al. (2007) Control of adipose triglyceride lipase action by serine 517 of perilipin A globally regulates protein kinase A-stimulated lipolysis in adipocytes. J Biol Chem 282: 996–1002. 17114792
44. Granneman JG, Moore HP, Granneman RL, Greenberg AS, Obin MS, et al. (2007) Analysis of lipolytic protein trafficking and interactions in adipocytes. J Biol Chem 282: 5726–5735. 17189257
45. Subramanian V, Rothenberg A, Gomez C, Cohen AW, Garcia A, et al. (2004) Perilipin A mediates the reversible binding of CGI-58 to lipid droplets in 3T3-L1 adipocytes. J Biol Chem 279: 42062–42071. 15292255
46. Wolins NE, Quaynor BK, Skinner JR, Schoenfish MJ, Tzekov A, et al. (2005) S3-12, Adipophilin, and TIP47 package lipid in adipocytes. J Biol Chem 280: 19146–19155. 15731108
47. Chyb S, Raghu P, Hardie RC, , (1999) Polyunsaturated fatty acids activate the Drosophila light-sensitive channels TRP and TRPL. Nature 397: 255–259. 9930700
48. Goldberg EM, Zidovetzki R, , (1997) Effects of dipalmitoylglycerol and fatty acids on membrane structure and protein kinase C activity. Biophys J 73: 2603–2614. 9370455
49. Yamaguchi T, Osumi T, , (2009) Chanarin-Dorfman syndrome: deficiency in CGI-58, a lipid droplet-bound coactivator of lipase. Biochim Biophys Acta 1791: 519–523. doi: 10.1016/j.bbalip.2008.10.012 19061969
50. Brenner S, , (1974) The genetics of Caenorhabditis elegans. Genetics 77: 71–94. 4366476
51. Kamath RS, Martinez-Campos M, Zipperlen P, Fraser AG, Ahringer J, , (2001) Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans. Genome Biol 2: 1–10. 11178274
52. Soukas AA, Kane EA, Carr CE, Melo JA, Ruvkun G, , (2009) Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans. Genes Dev 23: 496–511. doi: 10.1101/gad.1775409 19240135
53. Mak HY, Nelson LS, Basson M, Johnson CD, Ruvkun G, , (2006) Polygenic control of Caenorhabditis elegans fat storage. Nat Genet 38: 363–368. 16462744
54. Chitraju C, Trötzmüller M, Hartler J, Wolinski H, Thallinger GG, et al. (2012) Lipidomic analysis of lipid droplets from murine hepatocytes reveals distinct signatures for nutritional stress. J Lipid Res. 53: 2141–2152. doi: 10.1194/jlr.M028902 22872753
55. Miquel M, Browse J, , (1992) Arabidopsis mutants deficient in polyunsaturated fatty acid synthesis. Biochemical and genetic characterization of a plant oleoyl-phosphatidylcholine desaturase. J. Biol. Chem 267: 1502–1509. 1730697
56. Deline ML, Vrablik TL, Watts JL, . (2013) Dietary supplementation of polyunsaturated fatty acids in Caenorhabditis elegans. J Vis Exp.