메뉴 건너뛰기




Volumn 116, Issue 9, 2015, Pages 1527-1539

Pathogenesis of the Limb Manifestations and Exercise Limitations in Peripheral Artery Disease

Author keywords

exercise; metabolism; peripheral artery disease; peripheral vascular diseases; physiopathology; therapeutics

Indexed keywords

OXYGEN; PHOSPHODIESTERASE III INHIBITOR;

EID: 84937596773     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.116.303566     Document Type: Article
Times cited : (115)

References (162)
  • 1
    • 84877971906 scopus 로고    scopus 로고
    • Mechanisms of acute coronary syndromes and their implications for therapy
    • Libby P. Mechanisms of acute coronary syndromes and their implications for therapy. N Engl J Med. 2013;368:2004-2013. doi: 10.1056/ NEJMra1216063.
    • (2013) N Engl J Med , vol.368 , pp. 2004-2013
    • Libby, P.1
  • 4
    • 33747449559 scopus 로고    scopus 로고
    • Peripheral arterial disease: Morbidity and mortality implications
    • Golomb BA, Dang TT, Criqui MH. Peripheral arterial disease: morbidity and mortality implications. Circulation. 2006;114:688-699. doi: 10.1161/ CIRCULATIONAHA.105.593442.
    • (2006) Circulation , vol.114 , pp. 688-699
    • Golomb, B.A.1    Dang, T.T.2    Criqui, M.H.3
  • 5
    • 84858699318 scopus 로고    scopus 로고
    • A call to action: Women and peripheral artery disease: A scientific statement from the American Heart Association
    • American Heart Association Council on Peripheral Vascular Disease; Council on Cardiovascular Nursing; Council on Cardiovascular Radiology and Intervention; Council on Cardiovascular Surgery and Anesthesia; Council on Clinical Cardiology; Council on Epidemiology and Prevention
    • Hirsch AT, Allison MA, Gomes AS, Corriere MA, Duval S, Ershow AG, Hiatt WR, Karas RH, Lovell MB, McDermott MM, Mendes DM, Nussmeier NA, Treat-Jacobson D; American Heart Association Council on Peripheral Vascular Disease; Council on Cardiovascular Nursing; Council on Cardiovascular Radiology and Intervention; Council on Cardiovascular Surgery and Anesthesia; Council on Clinical Cardiology; Council on Epidemiology and Prevention. A call to action: women and peripheral artery disease: a scientific statement from the American Heart Association. Circulation. 2012;125:1449-1472. doi: 10.1161/CIR.0b013e31824c39ba.
    • (2012) Circulation , vol.125 , pp. 1449-1472
    • Hirsch, A.T.1    Allison, M.A.2    Gomes, A.S.3    Corriere, M.A.4    Duval, S.5    Ershow, A.G.6    Hiatt, W.R.7    Karas, R.H.8    Lovell, M.B.9    McDermott, M.M.10    Mendes, D.M.11    Nussmeier, N.A.12    Treat-Jacobson, D.13
  • 7
    • 30444453441 scopus 로고    scopus 로고
    • International prevalence, recognition, and treatment of cardiovascular risk factors in outpatients with atherothrombosis
    • Bhatt DL, Steg PG, Ohman EM, Hirsch AT, Ikeda Y, Mas JL, Goto S, Liau CS, Richard AJ, Röther J, Wilson PW; REACH Registry Investigators. International prevalence, recognition, and treatment of cardiovascular risk factors in outpatients with atherothrombosis. JAMA. 2006;295:180-189. doi: 10.1001/jama.295.2.180.
    • (2006) JAMA , vol.295 , pp. 180-189
    • Bhatt, D.L.1    Steg, P.G.2    Ohman, E.M.3    Hirsch, A.T.4    Ikeda, Y.5    Mas, J.L.6    Goto, S.7    Liau, C.S.8    Richard, A.J.9    Röther, J.10    Wilson, P.W.11
  • 8
    • 84883190881 scopus 로고    scopus 로고
    • Modifiable risk factor burden and the prevalence of peripheral artery disease in different vascular territories
    • Berger JS, Hochman J, Lobach I, Adelman MA, Riles TS, Rockman CB. Modifiable risk factor burden and the prevalence of peripheral artery disease in different vascular territories. J Vasc Surg. 2013;58:673-81.e1. doi: 10.1016/j.jvs.2013.01.053.
    • (2013) J Vasc Surg , vol.58 , pp. 673-673e1
    • Berger, J.S.1    Hochman, J.2    Lobach, I.3    Adelman, M.A.4    Riles, T.S.5    Rockman, C.B.6
  • 9
    • 84883038245 scopus 로고    scopus 로고
    • Peripheral artery disease and risk of cardiovascular events in patients with coronary artery disease: Insights from the Heart and Soul Study
    • Grenon SM, Vittinghoff E, Owens CD, Conte MS, Whooley M, Cohen BE. Peripheral artery disease and risk of cardiovascular events in patients with coronary artery disease: insights from the Heart and Soul Study. Vasc Med. 2013;18:176-184. doi: 10.1177/1358863X13493825.
    • (2013) Vasc Med , vol.18 , pp. 176-184
    • Grenon, S.M.1    Vittinghoff, E.2    Owens, C.D.3    Conte, M.S.4    Whooley, M.5    Cohen, B.E.6
  • 10
    • 78349290032 scopus 로고    scopus 로고
    • Inflammation in peripheral artery disease
    • Brevetti G, Giugliano G, Brevetti L, Hiatt WR. Inflammation in peripheral artery disease. Circulation. 2010;122:1862-1875. doi: 10.1161/ CIRCULATIONAHA.109.918417.
    • (2010) Circulation , vol.122 , pp. 1862-1875
    • Brevetti, G.1    Giugliano, G.2    Brevetti, L.3    Hiatt, W.R.4
  • 12
    • 79960386928 scopus 로고    scopus 로고
    • Secondary prevention and mortality in peripheral artery disease: National Health and Nutrition Examination Study, 1999 to 2004
    • Pande RL, Perlstein TS, Beckman JA, Creager MA. Secondary prevention and mortality in peripheral artery disease: National Health and Nutrition Examination Study, 1999 to 2004. Circulation. 2011;124:17-23. doi: 10.1161/CIRCULATIONAHA.110.003954.
    • (2011) Circulation , vol.124 , pp. 17-23
    • Pande, R.L.1    Perlstein, T.S.2    Beckman, J.A.3    Creager, M.A.4
  • 14
    • 84555203680 scopus 로고    scopus 로고
    • 2011 ACCF/AHA Focused Update of the Guideline for the Management of Patients with Peripheral Artery Disease (Updating the 2005 Guideline): A report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines
    • 2011 Writing Group Members; 2005 Writing Committee Members; ACCF/AHA Task Force Members. 2011 ACCF/AHA Focused Update of the Guideline for the Management of Patients With Peripheral Artery Disease (Updating the 2005 Guideline): a report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines. Circulation. 2011;124:2020-2045. doi: 10.1161/ CIR.0b013e31822e80c3.
    • (2011) Circulation , vol.124 , pp. 2020-2045
  • 15
    • 84904611110 scopus 로고    scopus 로고
    • Adherence to guideline- recommended therapy is associated with decreased major adverse cardiovascular events and major adverse limb events among patients with peripheral arterial disease
    • Armstrong EJ, Chen DC, Westin GG, Singh S, McCoach CE, Bang H, Yeo KK, Anderson D, Amsterdam EA, Laird JR. Adherence to guideline- recommended therapy is associated with decreased major adverse cardiovascular events and major adverse limb events among patients with peripheral arterial disease. J Am Heart Assoc. 2014;3:e000697. doi: 10.1161/JAHA.113.000697.
    • (2014) J Am Heart Assoc , vol.3
    • Armstrong, E.J.1    Chen, D.C.2    Westin, G.G.3    Singh, S.4    McCoach, C.E.5    Bang, H.6    Yeo, K.K.7    Anderson, D.8    Amsterdam, E.A.9    Laird, J.R.10
  • 16
    • 84870919920 scopus 로고    scopus 로고
    • Measurement and interpretation of the ankle-brachial index: A scientific statement from the American Heart Association
    • American Heart Association Council on Peripheral Vascular Disease; Council on Epidemiology and Prevention; Council on Clinical Cardiology; Council on Cardiovascular Nursing; Council on Cardiovascular Radiology and Intervention, and Council on Cardiovascular Surgery and Anesthesia
    • Aboyans V, Criqui MH, Abraham P, et al; American Heart Association Council on Peripheral Vascular Disease; Council on Epidemiology and Prevention; Council on Clinical Cardiology; Council on Cardiovascular Nursing; Council on Cardiovascular Radiology and Intervention, and Council on Cardiovascular Surgery and Anesthesia. Measurement and interpretation of the ankle-brachial index: a scientific statement from the American Heart Association. Circulation. 2012;126:2890-2909. doi: 10.1161/CIR.0b013e318276fbcb.
    • (2012) Circulation , vol.126 , pp. 2890-2909
    • Aboyans, V.1    Criqui, M.H.2    Abraham, P.3
  • 17
    • 34548492968 scopus 로고    scopus 로고
    • The role of CT and MRI in the assessment of peripheral vascular disease
    • von Ziegler F, Costa MA. The role of CT and MRI in the assessment of peripheral vascular disease. Curr Cardiol Rep. 2007;9:412-419.
    • (2007) Curr Cardiol Rep , vol.9 , pp. 412-419
    • Von Ziegler, F.1    Costa, M.A.2
  • 18
    • 0033593868 scopus 로고    scopus 로고
    • Exertional leg symptoms other than intermittent claudication are common in peripheral arterial disease
    • McDermott MM, Mehta S, Greenland P. Exertional leg symptoms other than intermittent claudication are common in peripheral arterial disease. Arch Intern Med. 1999;159:387-392.
    • (1999) Arch Intern Med , vol.159 , pp. 387-392
    • McDermott, M.M.1    Mehta, S.2    Greenland, P.3
  • 19
    • 0025676651 scopus 로고
    • Intermittent claudication, heart disease risk factors, and mortality. the Whitehall Study
    • Smith GD, Shipley MJ, Rose G. Intermittent claudication, heart disease risk factors, and mortality. The Whitehall Study. Circulation. 1990;82:1925-1931.
    • (1990) Circulation , vol.82 , pp. 1925-1931
    • Smith, G.D.1    Shipley, M.J.2    Rose, G.3
  • 21
  • 22
    • 0027328002 scopus 로고
    • Claudication pain and hemodynamic responses to exercise in younger and older peripheral arterial disease patients
    • Gardner AW. Claudication pain and hemodynamic responses to exercise in younger and older peripheral arterial disease patients. J Gerontol. 1993;48:M231-M236.
    • (1993) J Gerontol , vol.48 , pp. M231-M236
    • Gardner, A.W.1
  • 23
    • 0032969499 scopus 로고    scopus 로고
    • Relationship between free-living daily physical activity and peripheral circulation in patients with intermittent claudication
    • Gardner AW, Killewich LA, Katzel LI, Womack CJ, Montgomery PS, Otis RB, Fonong T. Relationship between free-living daily physical activity and peripheral circulation in patients with intermittent claudication. Angiology. 1999;50:289-297.
    • (1999) Angiology , vol.50 , pp. 289-297
    • Gardner, A.W.1    Killewich, L.A.2    Katzel, L.I.3    Womack, C.J.4    Montgomery, P.S.5    Otis, R.B.6    Fonong, T.7
  • 24
    • 0031904692 scopus 로고    scopus 로고
    • Assessment of free-living daily physical activity in older claudicants: Validation against the doubly labeled water technique
    • Gardner AW, Poehlman ET. Assessment of free-living daily physical activity in older claudicants: validation against the doubly labeled water technique. J Gerontol A Biol Sci Med Sci. 1998;53:M275-M280.
    • (1998) J Gerontol A Biol Sci Med Sci , vol.53 , pp. M275-M280
    • Gardner, A.W.1    Poehlman, E.T.2
  • 27
    • 0029401521 scopus 로고
    • Peripheral vascular anatomy, physiology, and pathophysiology
    • Wheeler EC, Brenner ZR. Peripheral vascular anatomy, physiology, and pathophysiology. AACN Clin Issues. 1995;6:505-514.
    • (1995) AACN Clin Issues , vol.6 , pp. 505-514
    • Wheeler, E.C.1    Brenner, Z.R.2
  • 28
    • 0017295365 scopus 로고
    • Poiseuille and his law
    • Pfitzner J. Poiseuille and his law. Anaesthesia. 1976;31:273-275.
    • (1976) Anaesthesia , vol.31 , pp. 273-275
    • Pfitzner, J.1
  • 29
    • 0013828425 scopus 로고
    • Leg blood flow at rest, during and after exercise in normal subjects and in patients with femoral artery occlusion
    • Hlavová J, Linhart J, Prerovský I, Ganz V, Fronêk A. Leg blood flow at rest, during and after exercise in normal subjects and in patients with femoral artery occlusion. Clin Sci. 1965;29:555-564.
    • (1965) Clin Sci , vol.29 , pp. 555-564
    • Hlavová, J.1    Linhart, J.2    Prerovský, I.3    Ganz, V.4    Fronêk, A.5
  • 31
    • 0017861802 scopus 로고
    • Lower leg blood flow in intermittent claudication
    • Sørlie D, Myhre K. Lower leg blood flow in intermittent claudication. Scand J Clin Lab Invest. 1978;38:171-179.
    • (1978) Scand J Clin Lab Invest , vol.38 , pp. 171-179
    • Sørlie, D.1    Myhre, K.2
  • 32
    • 84928161608 scopus 로고    scopus 로고
    • Pathophysiology of intermittent claudication
    • Creager MA, Dzau VJ, Loscalzo J, eds., 2nd ed. Philadelphia: Saunders Elsevier
    • Hiatt WR, Brass EP. Pathophysiology of intermittent claudication. In: Creager MA, Dzau VJ, Loscalzo J, eds. Vascular Medicine: A Companion to Braunwald's Heart Disease. 2nd ed. Philadelphia: Saunders Elsevier; 2013;223-230.
    • (2013) Vascular Medicine: A Companion to Braunwald's Heart Disease , pp. 223-230
    • Hiatt, W.R.1    Brass, E.P.2
  • 33
    • 0023119039 scopus 로고
    • Relation of oxygen uptake to work rate in normal men and men with circulatory disorders
    • Hansen JE, Sue DY, Oren A, Wasserman K. Relation of oxygen uptake to work rate in normal men and men with circulatory disorders. Am J Cardiol. 1987;59:669-674.
    • (1987) Am J Cardiol , vol.59 , pp. 669-674
    • Hansen, J.E.1    Sue, D.Y.2    Oren, A.3    Wasserman, K.4
  • 34
    • 0021721798 scopus 로고
    • Effect of aerobic conditioning on the peripheral circulation during chronic beta-adrenergic blockade
    • Hiatt WR, Marsh RC, Brammell HL, Fee C, Horwitz LD. Effect of aerobic conditioning on the peripheral circulation during chronic beta-adrenergic blockade. J Am Coll Cardiol. 1984;4:958-963.
    • (1984) J Am Coll Cardiol , vol.4 , pp. 958-963
    • Hiatt, W.R.1    Marsh, R.C.2    Brammell, H.L.3    Fee, C.4    Horwitz, L.D.5
  • 35
    • 0028348470 scopus 로고
    • Coupling of external to cellular respiration during exercise: The wisdom of the body revisited
    • Wasserman K. Coupling of external to cellular respiration during exercise: the wisdom of the body revisited. Am J Physiol. 1994;266:E519-E539.
    • (1994) Am J Physiol , vol.266 , pp. E519-E539
    • Wasserman, K.1
  • 36
    • 14044253385 scopus 로고    scopus 로고
    • Detection of peripheral vascular stenosis by assessing skeletal muscle flow reserve
    • Bragadeesh T, Sari I, Pascotto M, Micari A, Kaul S, Lindner JR. Detection of peripheral vascular stenosis by assessing skeletal muscle flow reserve. J Am Coll Cardiol. 2005;45:780-785. doi: 10.1016/j.jacc.2004.11.045.
    • (2005) J Am Coll Cardiol , vol.45 , pp. 780-785
    • Bragadeesh, T.1    Sari, I.2    Pascotto, M.3    Micari, A.4    Kaul, S.5    Lindner, J.R.6
  • 37
  • 38
    • 84903770952 scopus 로고    scopus 로고
    • Advanced 2-dimensional quantitative coronary angiographic analysis for prediction of fractional flow reserve in intermediate coronary stenoses
    • Opolski MP, Pregowski J, Kruk M, Kepka C, Staruch AD, Witkowski A. Advanced 2-dimensional quantitative coronary angiographic analysis for prediction of fractional flow reserve in intermediate coronary stenoses. J Thorac Imaging. 2014;29:217-223. doi: 10.1097/ RTI.0000000000000058.
    • (2014) J Thorac Imaging , vol.29 , pp. 217-223
    • Opolski, M.P.1    Pregowski, J.2    Kruk, M.3    Kepka, C.4    Staruch, A.D.5    Witkowski, A.6
  • 40
    • 84857650081 scopus 로고    scopus 로고
    • Use of fraction flow reserve to predict changes over time in management of superficial femoral artery
    • Lotfi AS, Sivalingam SK, Giugliano GR, Ashraf J, Visintainer P. Use of fraction flow reserve to predict changes over time in management of superficial femoral artery. J Interv Cardiol. 2012;25:71-77. doi: 10.1111/j.1540-8183.2011.00691.x.
    • (2012) J Interv Cardiol , vol.25 , pp. 71-77
    • Lotfi, A.S.1    Sivalingam, S.K.2    Giugliano, G.R.3    Ashraf, J.4    Visintainer, P.5
  • 41
    • 33747142775 scopus 로고    scopus 로고
    • Blood oxygenation level-dependent magnetic resonance imaging of the skeletal muscle in patients with peripheral arterial occlusive disease
    • Ledermann HP, Schulte AC, Heidecker HG, Aschwanden M, Jäger KA, Scheffler K, Steinbrich W, Bilecen D. Blood oxygenation level-dependent magnetic resonance imaging of the skeletal muscle in patients with peripheral arterial occlusive disease. Circulation. 2006;113:2929-2935. doi: 10.1161/CIRCULATIONAHA.105.605717.
    • (2006) Circulation , vol.113 , pp. 2929-2935
    • Ledermann, H.P.1    Schulte, A.C.2    Heidecker, H.G.3    Aschwanden, M.4    Jäger, K.A.5    Scheffler, K.6    Steinbrich, W.7    Bilecen, D.8
  • 43
    • 0030874355 scopus 로고    scopus 로고
    • Role of nitric oxide in skeletal muscle blood flow at rest and during dynamic exercise in humans
    • Hickner RC, Fisher JS, Ehsani AA, Kohrt WM. Role of nitric oxide in skeletal muscle blood flow at rest and during dynamic exercise in humans. Am J Physiol. 1997;273:H405-H410.
    • (1997) Am J Physiol , vol.273 , pp. H405-H410
    • Hickner, R.C.1    Fisher, J.S.2    Ehsani, A.A.3    Kohrt, W.M.4
  • 44
    • 0026071074 scopus 로고
    • Differential impairment of vasodilator responsiveness of peripheral resistance and conduit vessels in humans with atherosclerosis
    • Liao JK, Bettmann MA, Sandor T, Tucker JI, Coleman SM, Creager MA. Differential impairment of vasodilator responsiveness of peripheral resistance and conduit vessels in humans with atherosclerosis. Circ Res. 1991;68:1027-1034.
    • (1991) Circ Res , vol.68 , pp. 1027-1034
    • Liao, J.K.1    Bettmann, M.A.2    Sandor, T.3    Tucker, J.I.4    Coleman, S.M.5    Creager, M.A.6
  • 45
    • 0030742704 scopus 로고    scopus 로고
    • Dose-related effect of intravenous L-arginine on muscular blood flow of the calf in patients with peripheral vascular disease: A H215O positron emission tomography study
    • Schellong SM, Böger RH, Burchert W, Bode-Böger SM, Galland A, Frölich JC, Hundeshagen H, Alexander K. Dose-related effect of intravenous L-arginine on muscular blood flow of the calf in patients with peripheral vascular disease: a H215O positron emission tomography study. Clin Sci (Lond). 1997;93:159-165.
    • (1997) Clin Sci (Lond) , vol.93 , pp. 159-165
    • Schellong, S.M.1    Böger, R.H.2    Burchert, W.3    Bode-Böger, S.M.4    Galland, A.5    Frölich, J.C.6    Hundeshagen, H.7    Alexander, K.8
  • 46
    • 24444451218 scopus 로고
    • Effects of diabetes on monocyte-endothelial interactions and endothelial superoxide production in fructose-induced insulin-resistant and hypertensive rats
    • Tsao PS, Buitrago R, Chang H, Chen UDI, Reaven GM. Effects of diabetes on monocyte-endothelial interactions and endothelial superoxide production in fructose-induced insulin-resistant and hypertensive rats. Circulation. 1995;92:A2666.
    • (1995) Circulation , vol.92 , pp. A2666
    • Tsao, P.S.1    Buitrago, R.2    Chang, H.3    Chen, U.D.I.4    Reaven, G.M.5
  • 47
    • 0034104014 scopus 로고    scopus 로고
    • Treadmill exercise-induced release of endothelin-1 in patients with peripheral arterial occlusive disease at Fontaine stage IIb
    • Mangiafico RA, Malatino LS, Spada RS, Santonocito M, Messina R, Dell'Arte S, Attinà T. Treadmill exercise-induced release of endothelin-1 in patients with peripheral arterial occlusive disease at Fontaine stage IIb. Int Angiol. 2000;19:14-17.
    • (2000) Int Angiol , vol.19 , pp. 14-17
    • Mangiafico, R.A.1    Malatino, L.S.2    Spada, R.S.3    Santonocito, M.4    Messina, R.5    Dell'Arte, S.6    Attinà, T.7
  • 48
    • 0042887139 scopus 로고    scopus 로고
    • Endothelial dysfunction in peripheral arterial disease is related to increase in plasma markers of inflammation and severity of peripheral circulatory impairment but not to classic risk factors and atherosclerotic burden
    • Brevetti G, Silvestro A, Di Giacomo S, Bucur R, Di Donato A, Schiano V, Scopacasa F. Endothelial dysfunction in peripheral arterial disease is related to increase in plasma markers of inflammation and severity of peripheral circulatory impairment but not to classic risk factors and atherosclerotic burden. J Vasc Surg. 2003;38:374-379.
    • (2003) J Vasc Surg , vol.38 , pp. 374-379
    • Brevetti, G.1    Silvestro, A.2    Di Giacomo, S.3    Bucur, R.4    Di Donato, A.5    Schiano, V.6    Scopacasa, F.7
  • 49
    • 84897064208 scopus 로고    scopus 로고
    • Walking disability in patients with peripheral artery disease is associated with arterial endothelial function
    • Grenon SM, Chong K, Alley H, Nosova E, Gasper W, Hiramoto J, Boscardin WJ, Owens CD. Walking disability in patients with peripheral artery disease is associated with arterial endothelial function. J Vasc Surg. 2014;59:1025-1034. doi: 10.1016/j.jvs.2013.10.084.
    • (2014) J Vasc Surg , vol.59 , pp. 1025-1034
    • Grenon, S.M.1    Chong, K.2    Alley, H.3    Nosova, E.4    Gasper, W.5    Hiramoto, J.6    Boscardin, W.J.7    Owens, C.D.8
  • 50
    • 79959207961 scopus 로고    scopus 로고
    • Arterial dysfunction and functional performance in patients with peripheral artery disease: A review
    • Coutinho T, Rooke TW, Kullo IJ. Arterial dysfunction and functional performance in patients with peripheral artery disease: a review. Vasc Med. 2011;16:203-211. doi: 10.1177/1358863X11400935.
    • (2011) Vasc Med , vol.16 , pp. 203-211
    • Coutinho, T.1    Rooke, T.W.2    Kullo, I.J.3
  • 51
    • 2342537845 scopus 로고    scopus 로고
    • Inflammatory status and endothelial function in asymptomatic and symptomatic peripheral arterial disease
    • Silvestro A, Scopacasa F, Ruocco A, Oliva G, Schiano V, Zincarelli C, Brevetti G. Inflammatory status and endothelial function in asymptomatic and symptomatic peripheral arterial disease. Vasc Med. 2003;8:225-232.
    • (2003) Vasc Med , vol.8 , pp. 225-232
    • Silvestro, A.1    Scopacasa, F.2    Ruocco, A.3    Oliva, G.4    Schiano, V.5    Zincarelli, C.6    Brevetti, G.7
  • 52
    • 0035253105 scopus 로고    scopus 로고
    • Effects of exercise rehabilitation on endothelial reactivity in older patients with peripheral arterial disease
    • Brendle DC, Joseph LJ, Corretti MC, Gardner AW, Katzel LI. Effects of exercise rehabilitation on endothelial reactivity in older patients with peripheral arterial disease. Am J Cardiol. 2001;87:324-329.
    • (2001) Am J Cardiol , vol.87 , pp. 324-329
    • Brendle, D.C.1    Joseph, L.J.2    Corretti, M.C.3    Gardner, A.W.4    Katzel, L.I.5
  • 53
    • 84905577265 scopus 로고    scopus 로고
    • Effect of treadmill training on endothelial function and walking abilities in patients with peripheral arterial disease
    • Januszek R, Mika P, Konik A, Petriczek T, Nowobilski R, Nizankowski R. Effect of treadmill training on endothelial function and walking abilities in patients with peripheral arterial disease. J Cardiol. 2014;64:145-151. doi: 10.1016/j.jjcc.2013.12.002.
    • (2014) J Cardiol , vol.64 , pp. 145-151
    • Januszek, R.1    Mika, P.2    Konik, A.3    Petriczek, T.4    Nowobilski, R.5    Nizankowski, R.6
  • 54
    • 84900818845 scopus 로고    scopus 로고
    • Exercise performance and peripheral vascular insufficiency improve with AMPK activation in high-fat diet-fed mice
    • Baltgalvis KA, White K, Li W, et al. Exercise performance and peripheral vascular insufficiency improve with AMPK activation in high-fat diet-fed mice. Am J Physiol Heart Circ Physiol. 2014;306:H1128-H1145. doi: 10.1152/ajpheart.00839.2013.
    • (2014) Am J Physiol Heart Circ Physiol , vol.306 , pp. H1128-H1145
    • Baltgalvis, K.A.1    White, K.2    Li, W.3
  • 55
    • 66949151329 scopus 로고    scopus 로고
    • Skeletal muscle microvascular flow in progressive peripheral artery disease: Assessment with continuous arterial spin-labeling perfusion magnetic resonance imaging
    • Wu WC, Mohler E 3rd, Ratcliffe SJ, Wehrli FW, Detre JA, Floyd TF. Skeletal muscle microvascular flow in progressive peripheral artery disease: assessment with continuous arterial spin-labeling perfusion magnetic resonance imaging. J Am Coll Cardiol. 2009;53:2372-2377. doi: 10.1016/j.jacc.2009.03.033.
    • (2009) J Am Coll Cardiol , vol.53 , pp. 2372-2377
    • Wu, W.C.1    Mohler, E.2    Ratcliffe, S.J.3    Wehrli, F.W.4    Detre, J.A.5    Floyd, T.F.6
  • 56
    • 84871392697 scopus 로고    scopus 로고
    • Arterial spin labeling MR imaging reproducibly measures peak-exercise calf muscle perfusion: A study in patients with peripheral arterial disease and healthy volunteers
    • Pollak AW, Meyer CH, Epstein FH, Jiji RS, Hunter JR, Dimaria JM, Christopher JM, Kramer CM. Arterial spin labeling MR imaging reproducibly measures peak-exercise calf muscle perfusion: a study in patients with peripheral arterial disease and healthy volunteers. JACC Cardiovasc Imaging. 2012;5:1224-1230. doi: 10.1016/j.jcmg.2012.03.022.
    • (2012) JACC Cardiovasc Imaging , vol.5 , pp. 1224-1230
    • Pollak, A.W.1    Meyer, C.H.2    Epstein, F.H.3    Jiji, R.S.4    Hunter, J.R.5    Dimaria, J.M.6    Christopher, J.M.7    Kramer, C.M.8
  • 57
    • 43549090187 scopus 로고    scopus 로고
    • Limb stress-rest perfusion imaging with contrast ultrasound for the assessment of peripheral arterial disease severity
    • Lindner JR, Womack L, Barrett EJ, Weltman J, Price W, Harthun NL, Kaul S, Patrie JT. Limb stress-rest perfusion imaging with contrast ultrasound for the assessment of peripheral arterial disease severity. JACC Cardiovasc Imaging. 2008;1:343-350. doi: 10.1016/j.jcmg.2008.04.001.
    • (2008) JACC Cardiovasc Imaging , vol.1 , pp. 343-350
    • Lindner, J.R.1    Womack, L.2    Barrett, E.J.3    Weltman, J.4    Price, W.5    Harthun, N.L.6    Kaul, S.7    Patrie, J.T.8
  • 59
    • 0029560968 scopus 로고
    • Relation of haemostatic, fibrinolytic, and rheological variables to the angiographic extent of peripheral arterial occlusive disease
    • Woodburn KR, Lowe GD, Rumley A, Love J, Pollock JG. Relation of haemostatic, fibrinolytic, and rheological variables to the angiographic extent of peripheral arterial occlusive disease. Int Angiol. 1995;14:346-352.
    • (1995) Int Angiol , vol.14 , pp. 346-352
    • Woodburn, K.R.1    Lowe, G.D.2    Rumley, A.3    Love, J.4    Pollock, J.G.5
  • 60
    • 0015763507 scopus 로고
    • Clinical, haemodynamic, rheological, and biochemical findings in 126 patients with intermittent claudication
    • Dormandy JA, Hoare E, Colley J, Arrowsmith DE, Dormandy TL. Clinical, haemodynamic, rheological, and biochemical findings in 126 patients with intermittent claudication. Br Med J. 1973;4:576-581.
    • (1973) Br Med J , vol.4 , pp. 576-581
    • Dormandy, J.A.1    Hoare, E.2    Colley, J.3    Arrowsmith, D.E.4    Dormandy, T.L.5
  • 61
    • 0027212213 scopus 로고
    • Blood viscosity, fibrinogen, and activation of coagulation and leukocytes in peripheral arterial disease and the normal population in the Edinburgh Artery Study
    • Lowe GD, Fowkes FG, Dawes J, Donnan PT, Lennie SE, Housley E. Blood viscosity, fibrinogen, and activation of coagulation and leukocytes in peripheral arterial disease and the normal population in the Edinburgh Artery Study. Circulation. 1993;87:1915-1920.
    • (1993) Circulation , vol.87 , pp. 1915-1920
    • Lowe, G.D.1    Fowkes, F.G.2    Dawes, J.3    Donnan, P.T.4    Lennie, S.E.5    Housley, E.6
  • 62
    • 0027160374 scopus 로고
    • Cross-linked fibrin degradation products, progression of peripheral arterial disease, and risk of coronary heart disease
    • Fowkes FG, Lowe GD, Housley E, Rattray A, Rumley A, Elton RA, MacGregor IR, Dawes J. Cross-linked fibrin degradation products, progression of peripheral arterial disease, and risk of coronary heart disease. Lancet. 1993;342:84-86.
    • (1993) Lancet , vol.342 , pp. 84-86
    • Fowkes, F.G.1    Lowe, G.D.2    Housley, E.3    Rattray, A.4    Rumley, A.5    Elton, R.A.6    MacGregor, I.R.7    Dawes, J.8
  • 63
    • 77952573883 scopus 로고    scopus 로고
    • A pooled analysis of the durability and predictors of treatment response of cilostazol in patients with intermittent claudication
    • Pande RL, Hiatt WR, Zhang P, Hittel N, Creager MA. A pooled analysis of the durability and predictors of treatment response of cilostazol in patients with intermittent claudication. Vasc Med. 2010;15:181-188. doi: 10.1177/1358863X10361545.
    • (2010) Vasc Med , vol.15 , pp. 181-188
    • Pande, R.L.1    Hiatt, W.R.2    Zhang, P.3    Hittel, N.4    Creager, M.A.5
  • 64
    • 84879955459 scopus 로고    scopus 로고
    • Intermittent claudication: New targets for drug development
    • Brass EP. Intermittent claudication: new targets for drug development. Drugs. 2013;73:999-1014. doi: 10.1007/s40265-013-0078-3.
    • (2013) Drugs , vol.73 , pp. 999-1014
    • Brass, E.P.1
  • 65
    • 0031929569 scopus 로고    scopus 로고
    • Effect of cilostazol on walking distances in patients with intermittent claudication caused by peripheral vascular disease
    • discussion 274
    • Money SR, Herd JA, Isaacsohn JL, Davidson M, Cutler B, Heckman J, Forbes WP. Effect of cilostazol on walking distances in patients with intermittent claudication caused by peripheral vascular disease. J Vasc Surg. 1998;27:267-74; discussion 274.
    • (1998) J Vasc Surg , vol.27 , pp. 267-274
    • Money, S.R.1    Herd, J.A.2    Isaacsohn, J.L.3    Davidson, M.4    Cutler, B.5    Heckman, J.6    Forbes, W.P.7
  • 66
    • 33845296933 scopus 로고    scopus 로고
    • The novel phosphodiesterase inhibitor NM-702 improves claudication-limited exercise performance in patients with peripheral arterial disease
    • Brass EP, Anthony R, Cobb FR, Koda I, Jiao J, Hiatt WR. The novel phosphodiesterase inhibitor NM-702 improves claudication-limited exercise performance in patients with peripheral arterial disease. J Am Coll Cardiol. 2006;48:2539-2545. doi: 10.1016/j.jacc.2006.07.064.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 2539-2545
    • Brass, E.P.1    Anthony, R.2    Cobb, F.R.3    Koda, I.4    Jiao, J.5    Hiatt, W.R.6
  • 67
    • 84856098414 scopus 로고    scopus 로고
    • A phase II dose-ranging study of the phosphodiesterase inhibitor K-134 in patients with peripheral artery disease and claudication
    • Brass EP, Cooper LT, Morgan RE, Hiatt WR. A phase II dose-ranging study of the phosphodiesterase inhibitor K-134 in patients with peripheral artery disease and claudication. J Vasc Surg. 2012;55:381-389.e1. doi: 10.1016/j. jvs.2011.09.004.
    • (2012) J Vasc Surg , vol.55 , pp. 381-381e1
    • Brass, E.P.1    Cooper, L.T.2    Morgan, R.E.3    Hiatt, W.R.4
  • 69
    • 84868659585 scopus 로고    scopus 로고
    • Systematic review of the efficacy of cilostazol, naftidrofuryl oxalate and pentoxifylline for the treatment of intermittent claudication
    • Stevens JW, Simpson E, Harnan S, Squires H, Meng Y, Thomas S, Michaels J, Stansby G. Systematic review of the efficacy of cilostazol, naftidrofuryl oxalate and pentoxifylline for the treatment of intermittent claudication. Br J Surg. 2012;99:1630-1638. doi: 10.1002/bjs.8895.
    • (2012) Br J Surg , vol.99 , pp. 1630-1638
    • Stevens, J.W.1    Simpson, E.2    Harnan, S.3    Squires, H.4    Meng, Y.5    Thomas, S.6    Michaels, J.7    Stansby, G.8
  • 71
    • 0029874842 scopus 로고    scopus 로고
    • Oral naftidrofuryl. A review of its pharmacology and therapeutic use in the management of peripheral occlusive arterial disease
    • Barradell LB, Brogden RN. Oral naftidrofuryl. A review of its pharmacology and therapeutic use in the management of peripheral occlusive arterial disease. Drugs Aging. 1996;8:299-322.
    • (1996) Drugs Aging , vol.8 , pp. 299-322
    • Barradell, L.B.1    Brogden, R.N.2
  • 73
    • 0029746681 scopus 로고    scopus 로고
    • Effect of exercise training on skeletal muscle histology and metabolism in peripheral arterial disease
    • Hiatt WR, Regensteiner JG, Wolfel EE, Carry MR, Brass EP. Effect of exercise training on skeletal muscle histology and metabolism in peripheral arterial disease. J Appl Physiol (1985). 1996;81:780-788.
    • (1996) J Appl Physiol (1985) , vol.81 , pp. 780-788
    • Hiatt, W.R.1    Regensteiner, J.G.2    Wolfel, E.E.3    Carry, M.R.4    Brass, E.P.5
  • 74
    • 0028080415 scopus 로고
    • Superiority of treadmill walking exercise versus strength training for patients with peripheral arterial disease. Implications for the mechanism of the training response
    • Hiatt WR, Wolfel EE, Meier RH, Regensteiner JG. Superiority of treadmill walking exercise versus strength training for patients with peripheral arterial disease. Implications for the mechanism of the training response. Circulation. 1994;90:1866-1874.
    • (1994) Circulation , vol.90 , pp. 1866-1874
    • Hiatt, W.R.1    Wolfel, E.E.2    Meier, R.H.3    Regensteiner, J.G.4
  • 75
    • 83655214994 scopus 로고    scopus 로고
    • Supervised exercise versus primary stenting for claudication resulting from aortoiliac peripheral artery disease: Six-month outcomes from the claudication: Exercise versus endoluminal revascularization (CLEVER) study
    • Murphy TP, Cutlip DE, Regensteiner JG, et al; CLEVER Study Investigators. Supervised exercise versus primary stenting for claudication resulting from aortoiliac peripheral artery disease: six-month outcomes from the claudication: exercise versus endoluminal revascularization (CLEVER) study. Circulation. 2012;125:130-139. doi: 10.1161/CIRCULATIONAHA.111.075770.
    • (2012) Circulation , vol.125 , pp. 130-139
    • Murphy, T.P.1    Cutlip, D.E.2    Regensteiner, J.G.3
  • 76
    • 79952438900 scopus 로고    scopus 로고
    • Effect of propionyl-L-carnitine on a background of monitored exercise in patients with claudication secondary to peripheral artery disease
    • Hiatt WR, Creager MA, Amato A, Brass EP. Effect of propionyl-L-carnitine on a background of monitored exercise in patients with claudication secondary to peripheral artery disease. J Cardiopulm Rehabil Prev. 2011;31:125-132. doi: 10.1097/HCR.0b013e3181f1fd65.
    • (2011) J Cardiopulm Rehabil Prev , vol.31 , pp. 125-132
    • Hiatt, W.R.1    Creager, M.A.2    Amato, A.3    Brass, E.P.4
  • 77
    • 0014366296 scopus 로고
    • Metabolic evaluation of the leg blood flow in claudicating patients with arterial obstructions at different levels
    • Pernow B, Zetterquist S. Metabolic evaluation of the leg blood flow in claudicating patients with arterial obstructions at different levels. Scand J Clin Lab Invest. 1968;21:277-287.
    • (1968) Scand J Clin Lab Invest , vol.21 , pp. 277-287
    • Pernow, B.1    Zetterquist, S.2
  • 78
    • 33846210647 scopus 로고    scopus 로고
    • Limb hemodynamics are not predictive of functional capacity in patients with PAD
    • Szuba A, Oka RK, Harada R, Cooke JP. Limb hemodynamics are not predictive of functional capacity in patients with PAD. Vasc Med. 2006;11:155-163.
    • (2006) Vasc Med , vol.11 , pp. 155-163
    • Szuba, A.1    Oka, R.K.2    Harada, R.3    Cooke, J.P.4
  • 80
    • 39049149953 scopus 로고    scopus 로고
    • The vascular endothelin system in hypertension- recent patents and discoveries
    • Hynynen MM, Khalil RA. The vascular endothelin system in hypertension- recent patents and discoveries. Recent Pat Cardiovasc Drug Discov. 2006;1:95-108.
    • (2006) Recent Pat Cardiovasc Drug Discov , vol.1 , pp. 95-108
    • Hynynen, M.M.1    Khalil, R.A.2
  • 81
    • 34247847802 scopus 로고    scopus 로고
    • Ambrisentan, a non-peptide endothelin receptor antagonist
    • Vatter H, Seifert V. Ambrisentan, a non-peptide endothelin receptor antagonist. Cardiovasc Drug Rev. 2006;24:63-76. doi: 10.1111/j.1527-3466.2006.00063.x.
    • (2006) Cardiovasc Drug Rev , vol.24 , pp. 63-76
    • Vatter, H.1    Seifert, V.2
  • 82
    • 84898680570 scopus 로고    scopus 로고
    • Macitentan for the treatment of pulmonary arterial hypertension
    • Hong IS, Coe HV, Catanzaro LM. Macitentan for the treatment of pulmonary arterial hypertension. Ann Pharmacother. 2014;48:538-547. doi: 10.1177/1060028013518900.
    • (2014) Ann Pharmacother , vol.48 , pp. 538-547
    • Hong, I.S.1    Coe, H.V.2    Catanzaro, L.M.3
  • 84
    • 27744546647 scopus 로고    scopus 로고
    • Influence of glucose control and improvement of insulin resistance on microvascular blood flow and endothelial function in patients with diabetes mellitus type 2
    • Forst T, Lübben G, Hohberg C, Kann P, Sachara C, Gottschall V, Friedrich C, Rosskopf R, Pfützner A. Influence of glucose control and improvement of insulin resistance on microvascular blood flow and endothelial function in patients with diabetes mellitus type 2. Microcirculation. 2005;12:543-550. doi: 10.1080/10739680500253402.
    • (2005) Microcirculation , vol.12 , pp. 543-550
    • Forst, T.1    Lübben, G.2    Hohberg, C.3    Kann, P.4    Sachara, C.5    Gottschall, V.6    Friedrich, C.7    Rosskopf, R.8    Pfützner, A.9
  • 85
    • 33644687456 scopus 로고    scopus 로고
    • Short-term pioglitazone treatment improves vascular function irrespective of metabolic changes in patients with type 2 diabetes
    • Martens FM, Visseren FL, de Koning EJ, Rabelink TJ. Short-term pioglitazone treatment improves vascular function irrespective of metabolic changes in patients with type 2 diabetes. J Cardiovasc Pharmacol. 2005;46:773-778.
    • (2005) J Cardiovasc Pharmacol , vol.46 , pp. 773-778
    • Martens, F.M.1    Visseren, F.L.2    De Koning, E.J.3    Rabelink, T.J.4
  • 86
    • 69249215302 scopus 로고    scopus 로고
    • Pioglitazone improves endothelial function with increased adiponectin and high-density lipoprotein cholesterol levels in type 2 diabetes
    • Tsuchiya K, Akaza I, Yoshimoto T, Hirata Y. Pioglitazone improves endothelial function with increased adiponectin and high-density lipoprotein cholesterol levels in type 2 diabetes. Endocr J. 2009;56:691-698.
    • (2009) Endocr J , vol.56 , pp. 691-698
    • Tsuchiya, K.1    Akaza, I.2    Yoshimoto, T.3    Hirata, Y.4
  • 87
    • 0028170663 scopus 로고
    • Systemic responses in patients with intermittent claudication after treadmill exercise
    • Edwards AT, Blann AD, Suarez-Mendez VJ, Lardi AM, McCollum CN. Systemic responses in patients with intermittent claudication after treadmill exercise. Br J Surg. 1994;81:1738-1741.
    • (1994) Br J Surg , vol.81 , pp. 1738-1741
    • Edwards, A.T.1    Blann, A.D.2    Suarez-Mendez, V.J.3    Lardi, A.M.4    McCollum, C.N.5
  • 89
    • 0029550253 scopus 로고
    • Oxidative stress is present in atherosclerotic peripheral arterial disease and further increased by diabetes mellitus
    • Belch JJ, Mackay IR, Hill A, Jennings P, McCollum P. Oxidative stress is present in atherosclerotic peripheral arterial disease and further increased by diabetes mellitus. Int Angiol. 1995;14:385-388.
    • (1995) Int Angiol , vol.14 , pp. 385-388
    • Belch, J.J.1    Mackay, I.R.2    Hill, A.3    Jennings, P.4    McCollum, P.5
  • 91
    • 0038819007 scopus 로고    scopus 로고
    • High circulating levels of cytokines (IL-6 and TNFalpha), adhesion molecules (VCAM-1 and ICAM-1) and selectins in patients with peripheral arterial disease at rest and after a treadmill test
    • Signorelli SS, Mazzarino MC, Di Pino L, Malaponte G, Porto C, Pennisi G, Marchese G, Costa MP, Digrandi D, Celotta G, Virgilio V. High circulating levels of cytokines (IL-6 and TNFalpha), adhesion molecules (VCAM-1 and ICAM-1) and selectins in patients with peripheral arterial disease at rest and after a treadmill test. Vasc Med. 2003;8:15-19.
    • (2003) Vasc Med , vol.8 , pp. 15-19
    • Signorelli, S.S.1    Mazzarino, M.C.2    Di Pino, L.3    Malaponte, G.4    Porto, C.5    Pennisi, G.6    Marchese, G.7    Costa, M.P.8    Digrandi, D.9    Celotta, G.10    Virgilio, V.11
  • 92
    • 0029028967 scopus 로고
    • Von Willebrand factor soluble P-selectin tissue plasminogen activator and plasminogen activator inhibitor in atherosclerosis
    • Blann AD, Dobrotova M, Kubisz P, McCollum CN. von Willebrand factor, soluble P-selectin, tissue plasminogen activator and plasminogen activator inhibitor in atherosclerosis. Thromb Haemost. 1995;74:626-630.
    • (1995) Thromb Haemost , vol.74 , pp. 626-630
    • Blann, A.D.1    Dobrotova, M.2    Kubisz, P.3    McCollum, C.N.4
  • 94
    • 33645729951 scopus 로고    scopus 로고
    • Markers of vascular inflammation are associated with the extent of atherosclerosis assessed as angiographic score and treadmill walking distances in patients with peripheral arterial occlusive disease
    • Nylaende M, Kroese A, Stranden E, Morken B, Sandbaek G, Lindahl AK, Arnesen H, Seljeflot I. Markers of vascular inflammation are associated with the extent of atherosclerosis assessed as angiographic score and treadmill walking distances in patients with peripheral arterial occlusive disease. Vasc Med. 2006;11:21-28.
    • (2006) Vasc Med , vol.11 , pp. 21-28
    • Nylaende, M.1    Kroese, A.2    Stranden, E.3    Morken, B.4    Sandbaek, G.5    Lindahl, A.K.6    Arnesen, H.7    Seljeflot, I.8
  • 97
    • 84880835481 scopus 로고    scopus 로고
    • Association of clinical attributes and treadmill walking performance in patients with claudication due to peripheral artery disease
    • Brass EP, Cooper LT, Hanson P, Hiatt WR. Association of clinical attributes and treadmill walking performance in patients with claudication due to peripheral artery disease. J Vasc Surg. 2013;58:396-403. doi: 10.1016/j.jvs.2012.12.077.
    • (2013) J Vasc Surg , vol.58 , pp. 396-403
    • Brass, E.P.1    Cooper, L.T.2    Hanson, P.3    Hiatt, W.R.4
  • 98
    • 84863738048 scopus 로고    scopus 로고
    • Molecular mechanisms of superoxide production by the mitochondrial respiratory chain
    • Dröse S, Brandt U. Molecular mechanisms of superoxide production by the mitochondrial respiratory chain. Adv Exp Med Biol. 2012;748:145-169. doi: 10.1007/978-1-4614-3573-0-6.
    • (2012) Adv Exp Med Biol , vol.748 , pp. 145-169
    • Dröse, S.1    Brandt, U.2
  • 99
    • 0028633411 scopus 로고
    • Exercise in patients with intermittent claudication results in the generation of oxygen derived free radicals and endothelial damage
    • Hickman P, Harrison DK, Hill A, McLaren M, Tamei H, McCollum PT, Belch JJ. Exercise in patients with intermittent claudication results in the generation of oxygen derived free radicals and endothelial damage. Adv Exp Med Biol. 1994;361:565-570.
    • (1994) Adv Exp Med Biol , vol.361 , pp. 565-570
    • Hickman, P.1    Harrison, D.K.2    Hill, A.3    McLaren, M.4    Tamei, H.5    McCollum, P.T.6    Belch, J.J.7
  • 101
    • 77957219707 scopus 로고
    • Marked increase in the number and variety of mitochondrial DNA rearrangements in aging human skeletal muscle
    • Melov S, Shoffner JM, Kaufman A, Wallace DC. Marked increase in the number and variety of mitochondrial DNA rearrangements in aging human skeletal muscle. Nucleic Acids Res. 1995;23:4122-4126.
    • (1995) Nucleic Acids Res , vol.23 , pp. 4122-4126
    • Melov, S.1    Shoffner, J.M.2    Kaufman, A.3    Wallace, D.C.4
  • 102
    • 0032934572 scopus 로고    scopus 로고
    • Skeletal muscle mitochondrial DNA injury in patients with unilateral peripheral arterial disease
    • Bhat HK, Hiatt WR, Hoppel CL, Brass EP. Skeletal muscle mitochondrial DNA injury in patients with unilateral peripheral arterial disease. Circulation. 1999;99:807-812.
    • (1999) Circulation , vol.99 , pp. 807-812
    • Bhat, H.K.1    Hiatt, W.R.2    Hoppel, C.L.3    Brass, E.P.4
  • 103
    • 37849002320 scopus 로고    scopus 로고
    • Modulation of skeletal muscle antioxidant defense by exercise: Role of redox signaling
    • Ji LL. Modulation of skeletal muscle antioxidant defense by exercise: role of redox signaling. Free Radic Biol Med. 2008;44:142-152. doi: 10.1016/j.freeradbiomed.2007.02.031.
    • (2008) Free Radic Biol Med , vol.44 , pp. 142-152
    • Ji, L.L.1
  • 106
    • 4344681454 scopus 로고    scopus 로고
    • Thioredoxin induction of peripheral blood mononuclear cells in mice in response to a single bout of swimming exercise
    • Sumida S, Nakamura H, Yodoi J. Thioredoxin induction of peripheral blood mononuclear cells in mice in response to a single bout of swimming exercise. Gen Physiol Biophys. 2004;23:241-249.
    • (2004) Gen Physiol Biophys , vol.23 , pp. 241-249
    • Sumida, S.1    Nakamura, H.2    Yodoi, J.3
  • 108
    • 0030951798 scopus 로고    scopus 로고
    • Leukocyte adhesion-structure and function of human leukocyte beta2-integrins and their cellular ligands
    • Gahmberg CG, Tolvanen M, Kotovuori P. Leukocyte adhesion-structure and function of human leukocyte beta2-integrins and their cellular ligands. Eur J Biochem. 1997;245:215-232.
    • (1997) Eur J Biochem , vol.245 , pp. 215-232
    • Gahmberg, C.G.1    Tolvanen, M.2    Kotovuori, P.3
  • 109
    • 74049088289 scopus 로고    scopus 로고
    • Treatment of multiple sclerosis: Role of natalizumab
    • Comi G. Treatment of multiple sclerosis: role of natalizumab. Neurol Sci. 2009;30 Suppl 2:S155-S158. doi: 10.1007/s10072-009-0147-2.
    • (2009) Neurol Sci , vol.30 , pp. S155-S158
    • Comi, G.1
  • 111
    • 0035940577 scopus 로고    scopus 로고
    • Use of anti-ICAM-1 therapy in ischemic stroke: Results of the Enlimomab Acute Stroke Trial
    • Enlinomab Acute Stroke Investigators. Use of anti-ICAM-1 therapy in ischemic stroke: results of the Enlimomab Acute Stroke Trial. Neurology. 2001;57:1428-1434.
    • (2001) Neurology , vol.57 , pp. 1428-1434
  • 112
    • 0032135083 scopus 로고    scopus 로고
    • Very late antigen 4 (VLA4) antagonists as anti-inflammatory agents
    • Lin KC, Castro AC. Very late antigen 4 (VLA4) antagonists as anti-inflammatory agents. Curr Opin Chem Biol. 1998;2:453-457.
    • (1998) Curr Opin Chem Biol , vol.2 , pp. 453-457
    • Lin, K.C.1    Castro, A.C.2
  • 114
    • 84877755222 scopus 로고    scopus 로고
    • Pharmacological control of platelet-leukocyte interactions by the human anti-P-selectin antibody inclacumab-preclinical and clinical studies
    • Kling D, Stucki C, Kronenberg S, Tuerck D, Rhéaume E, Tardif JC, Gaudreault J, Schmitt C. Pharmacological control of platelet-leukocyte interactions by the human anti-P-selectin antibody inclacumab-preclinical and clinical studies. Thromb Res. 2013;131:401-410. doi: 10.1016/j. thromres.2013.02.020.
    • (2013) Thromb Res , vol.131 , pp. 401-410
    • Kling, D.1    Stucki, C.2    Kronenberg, S.3    Tuerck, D.4    Rhéaume, E.5    Tardif, J.C.6    Gaudreault, J.7    Schmitt, C.8
  • 115
    • 84873276032 scopus 로고    scopus 로고
    • Effect of ramipril on walking times and quality of life among patients with peripheral artery disease and intermittent claudication: A randomized controlled trial
    • Ahimastos AA, Walker PJ, Askew C, Leicht A, Pappas E, Blombery P, Reid CM, Golledge J, Kingwell BA. Effect of ramipril on walking times and quality of life among patients with peripheral artery disease and intermittent claudication: a randomized controlled trial. JAMA. 2013;309:453-460. doi: 10.1001/jama.2012.216237.
    • (2013) JAMA , vol.309 , pp. 453-460
    • Ahimastos, A.A.1    Walker, P.J.2    Askew, C.3    Leicht, A.4    Pappas, E.5    Blombery, P.6    Reid, C.M.7    Golledge, J.8    Kingwell, B.A.9
  • 116
    • 84897552462 scopus 로고    scopus 로고
    • Potential vascular mechanisms of ramipril induced increases in walking ability in patients with intermittent claudication
    • Ahimastos AA, Latouche C, Natoli AK, Reddy-luthmoodoo M, Golledge J, Kingwell BA. Potential vascular mechanisms of ramipril induced increases in walking ability in patients with intermittent claudication. Circ Res. 2014;114:1144-1155. doi: 10.1161/CIRCRESAHA. 114.302420.
    • (2014) Circ Res , vol.114 , pp. 1144-1155
    • Ahimastos, A.A.1    Latouche, C.2    Natoli, A.K.3    Reddy-Luthmoodoo, M.4    Golledge, J.5    Kingwell, B.A.6
  • 117
    • 79953308839 scopus 로고    scopus 로고
    • Do angiotensin converting enzyme inhibitors improve walking distance in patients with symptomatic lower limb arterial disease? A systematic review and meta-analysis of randomised controlled trials
    • Shahin Y, Mazari F, Chetter I. Do angiotensin converting enzyme inhibitors improve walking distance in patients with symptomatic lower limb arterial disease? A systematic review and meta-analysis of randomised controlled trials. Int J Surg. 2011;9:209-213. doi: 10.1016/j. ijsu.2010.12.006.
    • (2011) Int J Surg , vol.9 , pp. 209-213
    • Shahin, Y.1    Mazari, F.2    Chetter, I.3
  • 118
    • 84874456704 scopus 로고    scopus 로고
    • A systematic review and meta-analysis of propionyl-L-carnitine effects on exercise performance in patients with claudication
    • Brass EP, Koster D, Hiatt WR, Amato A. A systematic review and meta-analysis of propionyl-L-carnitine effects on exercise performance in patients with claudication. Vasc Med. 2013;18:3-12. doi: 10.1177/1358863X12467491.
    • (2013) Vasc Med , vol.18 , pp. 3-12
    • Brass, E.P.1    Koster, D.2    Hiatt, W.R.3    Amato, A.4
  • 119
    • 0033596281 scopus 로고    scopus 로고
    • Effect of statins on risk of coronary disease: A meta-analysis of randomized controlled trials
    • LaRosa JC, He J, Vupputuri S. Effect of statins on risk of coronary disease: a meta-analysis of randomized controlled trials. JAMA. 1999;282:2340-2346.
    • (1999) JAMA , vol.282 , pp. 2340-2346
    • LaRosa, J.C.1    He, J.2    Vupputuri, S.3
  • 121
    • 0141504333 scopus 로고    scopus 로고
    • Cholesterol reduction with atorvastatin improves walking distance in patients with peripheral arterial disease
    • Mohler ER 3rd, Hiatt WR, Creager MA. Cholesterol reduction with atorvastatin improves walking distance in patients with peripheral arterial disease. Circulation. 2003;108:1481-1486. doi: 10.1161/01. CIR.0000090686.57897.F5.
    • (2003) Circulation , vol.108 , pp. 1481-1486
    • Mohler, E.R.1    Hiatt, W.R.2    Creager, M.A.3
  • 123
    • 18844451291 scopus 로고    scopus 로고
    • Skeletal muscle phenotype is associated with exercise tolerance in patients with peripheral arterial disease
    • Askew CD, Green S, Walker PJ, Kerr GK, Green AA, Williams AD, Febbraio MA. Skeletal muscle phenotype is associated with exercise tolerance in patients with peripheral arterial disease. J Vasc Surg. 2005;41:802-807. doi: 10.1016/j.jvs.2005.01.037.
    • (2005) J Vasc Surg , vol.41 , pp. 802-807
    • Askew, C.D.1    Green, S.2    Walker, P.J.3    Kerr, G.K.4    Green, A.A.5    Williams, A.D.6    Febbraio, M.A.7
  • 130
    • 70349656513 scopus 로고    scopus 로고
    • Pathophysiological changes in calf muscle predict mobility loss at 2-year follow-up in men and women with peripheral arterial disease
    • McDermott MM, Ferrucci L, Guralnik J, Tian L, Liu K, Hoff F, Liao Y, Criqui MH. Pathophysiological changes in calf muscle predict mobility loss at 2-year follow-up in men and women with peripheral arterial disease. Circulation. 2009;120:1048-1055. doi: 10.1161/ CIRCULATIONAHA.108.842328.
    • (2009) Circulation , vol.120 , pp. 1048-1055
    • McDermott, M.M.1    Ferrucci, L.2    Guralnik, J.3    Tian, L.4    Liu, K.5    Hoff, F.6    Liao, Y.7    Criqui, M.H.8
  • 131
    • 84858684155 scopus 로고    scopus 로고
    • Calf muscle characteristics, strength measures, and mortality in peripheral arterial disease: A longitudinal study
    • McDermott MM, Liu K, Tian L, Guralnik JM, Criqui MH, Liao Y, Ferrucci L. Calf muscle characteristics, strength measures, and mortality in peripheral arterial disease: a longitudinal study. J Am Coll Cardiol. 2012;59:1159-1167. doi: 10.1016/j.jacc.2011.12.019.
    • (2012) J Am Coll Cardiol , vol.59 , pp. 1159-1167
    • McDermott, M.M.1    Liu, K.2    Tian, L.3    Guralnik, J.M.4    Criqui, M.H.5    Liao, Y.6    Ferrucci, L.7
  • 134
    • 84887971561 scopus 로고    scopus 로고
    • A phase 2, randomized, placebo controlled, multiple ascending-dose study of ACE-031, a soluble activin receptor Type IIB, in boys with Duchenne muscular dystrophy (DMD)
    • Campbell C, Escolar D, Mah J. A phase 2, randomized, placebo controlled, multiple ascending-dose study of ACE-031, a soluble activin receptor Type IIB, in boys with Duchenne muscular dystrophy (DMD). Neurology. 2012;78:P04.088.
    • (2012) Neurology , vol.78 , pp. 04088
    • Campbell, C.1    Escolar, D.2    Mah, J.3
  • 135
    • 44849140764 scopus 로고    scopus 로고
    • A phase I/IItrial of MYO-029 in adult subjects with muscular dystrophy
    • Wagner KR, Fleckenstein JL, Amato AA, et al. A phase I/IItrial of MYO-029 in adult subjects with muscular dystrophy. Ann Neurol. 2008;63:561-571. doi: 10.1002/ana.21338.
    • (2008) Ann Neurol , vol.63 , pp. 561-571
    • Wagner, K.R.1    Fleckenstein, J.L.2    Amato, A.A.3
  • 136
    • 84942940465 scopus 로고    scopus 로고
    • Deleted in proof
    • Deleted in proof.
  • 138
    • 0035407932 scopus 로고    scopus 로고
    • Regulation of oxygen consumption at exercise onset: Is it really controversial?
    • Grassi B. Regulation of oxygen consumption at exercise onset: is it really controversial? Exerc Sport Sci Rev. 2001;29:134-138.
    • (2001) Exerc Sport Sci Rev , vol.29 , pp. 134-138
    • Grassi, B.1
  • 139
    • 0032841029 scopus 로고    scopus 로고
    • Oxygen uptake kinetics during exercise are slowed in patients with peripheral arterial disease
    • Bauer TA, Regensteiner JG, Brass EP, Hiatt WR. Oxygen uptake kinetics during exercise are slowed in patients with peripheral arterial disease. J Appl Physiol (1985). 1999;87:809-816.
    • (1999) J Appl Physiol (1985) , vol.87 , pp. 809-816
    • Bauer, T.A.1    Regensteiner, J.G.2    Brass, E.P.3    Hiatt, W.R.4
  • 140
    • 34247639142 scopus 로고    scopus 로고
    • Skeletal muscle StO2 kinetics are slowed during low work rate calf exercise in peripheral arterial disease
    • Bauer TA, Brass EP, Barstow TJ, Hiatt WR. Skeletal muscle StO2 kinetics are slowed during low work rate calf exercise in peripheral arterial disease. Eur J Appl Physiol. 2007;100:143-151. doi: 10.1007/ s00421-007-0412-0.
    • (2007) Eur J Appl Physiol , vol.100 , pp. 143-151
    • Bauer, T.A.1    Brass, E.P.2    Barstow, T.J.3    Hiatt, W.R.4
  • 141
    • 1642300428 scopus 로고    scopus 로고
    • Walking performance, oxygen uptake kinetics and resting muscle pyruvate dehydrogenase complex activity in peripheral arterial disease
    • Barker GA, Green S, Green AA, Walker PJ. Walking performance, oxygen uptake kinetics and resting muscle pyruvate dehydrogenase complex activity in peripheral arterial disease. Clin Sci (Lond). 2004;106:241-249. doi: 10.1042/CS20030244.
    • (2004) Clin Sci (Lond) , vol.106 , pp. 241-249
    • Barker, G.A.1    Green, S.2    Green, A.A.3    Walker, P.J.4
  • 142
    • 0028886321 scopus 로고
    • Calf muscle mitochondrial and glycogenolytic ATP synthesis in patients with claudication due to peripheral vascular disease analysed using 31P magnetic resonance spectroscopy
    • Kemp GJ, Hands LJ, Ramaswami G, Taylor DJ, Nicolaides A, Amato A, Radda GK. Calf muscle mitochondrial and glycogenolytic ATP synthesis in patients with claudication due to peripheral vascular disease analysed using 31P magnetic resonance spectroscopy. Clin Sci (Lond). 1995;89:581-590.
    • (1995) Clin Sci (Lond) , vol.89 , pp. 581-590
    • Kemp, G.J.1    Hands, L.J.2    Ramaswami, G.3    Taylor, D.J.4    Nicolaides, A.5    Amato, A.6    Radda, G.K.7
  • 143
    • 0000168750 scopus 로고
    • Mitochondrial complexes I, II, III, IV, and v in myocardial ischemia and autolysis
    • Rouslin W. Mitochondrial complexes I, II, III, IV, and V in myocardial ischemia and autolysis. Am J Physiol. 1983;244:H743-H748.
    • (1983) Am J Physiol , vol.244 , pp. H743-H748
    • Rouslin, W.1
  • 144
    • 0035012131 scopus 로고    scopus 로고
    • Decreased NADH dehydrogenase and ubiquinol-cytochrome c oxidoreductase in peripheral arterial disease
    • Brass EP, Hiatt WR, Gardner AW, Hoppel CL. Decreased NADH dehydrogenase and ubiquinol-cytochrome c oxidoreductase in peripheral arterial disease. Am J Physiol Heart Circ Physiol. 2001;280:H603-H609.
    • (2001) Am J Physiol Heart Circ Physiol , vol.280 , pp. H603-H609
    • Brass, E.P.1    Hiatt, W.R.2    Gardner, A.W.3    Hoppel, C.L.4
  • 146
    • 0023893052 scopus 로고
    • Carnitine
    • Bieber LL. Carnitine. Annu Rev Biochem. 1988;57:261-283. doi: 10.1146/annurev.bi.57.070188.001401.
    • (1988) Annu Rev Biochem , vol.57 , pp. 261-283
    • Bieber, L.L.1
  • 147
    • 0019325901 scopus 로고
    • Relationship between acid-soluble carnitine and coenzyme A pools in vivo
    • Brass EP, Hoppel CL. Relationship between acid-soluble carnitine and coenzyme A pools in vivo. Biochem J. 1980;190:495-504.
    • (1980) Biochem J , vol.190 , pp. 495-504
    • Brass, E.P.1    Hoppel, C.L.2
  • 148
    • 0023180873 scopus 로고
    • Carnitine metabolism during exercise in patients with peripheral vascular disease
    • Hiatt WR, Nawaz D, Brass EP. Carnitine metabolism during exercise in patients with peripheral vascular disease. J Appl Physiol (1985). 1987;62:2383-2387.
    • (1987) J Appl Physiol (1985) , vol.62 , pp. 2383-2387
    • Hiatt, W.R.1    Nawaz, D.2    Brass, E.P.3
  • 149
    • 0026683401 scopus 로고
    • Skeletal muscle carnitine metabolism in patients with unilateral peripheral arterial disease
    • Hiatt WR, Wolfel EE, Regensteiner JG, Brass EP. Skeletal muscle carnitine metabolism in patients with unilateral peripheral arterial disease. J Appl Physiol (1985). 1992;73:346-353.
    • (1992) J Appl Physiol (1985) , vol.73 , pp. 346-353
    • Hiatt, W.R.1    Wolfel, E.E.2    Regensteiner, J.G.3    Brass, E.P.4
  • 150
    • 1642300428 scopus 로고    scopus 로고
    • Walking performance, oxygen uptake kinetics and resting muscle pyruvate dehydrogenase complex activity in peripheral arterial disease
    • Barker GA, Green S, Green AA, Walker PJ. Walking performance, oxygen uptake kinetics and resting muscle pyruvate dehydrogenase complex activity in peripheral arterial disease. Clin Sci (Lond). 2004;106:241-249. doi: 10.1042/CS20030244.
    • (2004) Clin Sci (Lond) , vol.106 , pp. 241-249
    • Barker, G.A.1    Green, S.2    Green, A.A.3    Walker, P.J.4
  • 151
    • 84880673845 scopus 로고    scopus 로고
    • Pharmacological approaches to restore mitochondrial function
    • Andreux PA, Houtkooper RH, Auwerx J. Pharmacological approaches to restore mitochondrial function. Nat Rev Drug Discov. 2013;12:465-483. doi: 10.1038/nrd4023.
    • (2013) Nat Rev Drug Discov , vol.12 , pp. 465-483
    • Andreux, P.A.1    Houtkooper, R.H.2    Auwerx, J.3
  • 152
    • 0036250153 scopus 로고    scopus 로고
    • Skeletal muscle mitochondrial ATP production rate and walking performance in peripheral arterial disease
    • Hou XY, Green S, Askew CD, Barker G, Green A, Walker PJ. Skeletal muscle mitochondrial ATP production rate and walking performance in peripheral arterial disease. Clin Physiol Funct Imaging. 2002;22:226-232.
    • (2002) Clin Physiol Funct Imaging , vol.22 , pp. 226-232
    • Hou, X.Y.1    Green, S.2    Askew, C.D.3    Barker, G.4    Green, A.5    Walker, P.J.6
  • 153
    • 10744228606 scopus 로고    scopus 로고
    • Endurance training in humans leads to fiber type-specific increases in levels of peroxisome proliferator-activated receptor-gamma coactivator-1 and peroxisome proliferator-activated receptor-alpha in skeletal muscle
    • Russell AP, Feilchenfeldt J, Schreiber S, Praz M, Crettenand A, Gobelet C, Meier CA, Bell DR, Kralli A, Giacobino JP, Dériaz O. Endurance training in humans leads to fiber type-specific increases in levels of peroxisome proliferator-activated receptor-gamma coactivator-1 and peroxisome proliferator-activated receptor-alpha in skeletal muscle. Diabetes. 2003;52:2874-2881.
    • (2003) Diabetes , vol.52 , pp. 2874-2881
    • Russell, A.P.1    Feilchenfeldt, J.2    Schreiber, S.3    Praz, M.4    Crettenand, A.5    Gobelet, C.6    Meier, C.A.7    Bell, D.R.8    Kralli, A.9    Giacobino, J.P.10    Dériaz, O.11
  • 155
    • 83855160814 scopus 로고    scopus 로고
    • Dissecting the role of peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) in colon breast and lung carcinogenesis
    • Peters JM, Foreman JE, Gonzalez FJ. Dissecting the role of peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) in colon, breast, and lung carcinogenesis. Cancer Metastasis Rev. 2011;30:619-640. doi: 10.1007/ s10555-011-9320-1.
    • (2011) Cancer Metastasis Rev , vol.30 , pp. 619-640
    • Peters, J.M.1    Foreman, J.E.2    Gonzalez, F.J.3
  • 156
    • 77955347446 scopus 로고    scopus 로고
    • Sirtuin 3, a new target of PGC-1alpha, plays an important role in the suppression of ROS and mitochondrial biogenesis
    • Kong X, Wang R, Xue Y, Liu X, Zhang H, Chen Y, Fang F, Chang Y. Sirtuin 3, a new target of PGC-1alpha, plays an important role in the suppression of ROS and mitochondrial biogenesis. PLoS One. 2010;5:e11707. doi: 10.1371/journal.pone.0011707.
    • (2010) PLoS One , vol.5
    • Kong, X.1    Wang, R.2    Xue, Y.3    Liu, X.4    Zhang, H.5    Chen, Y.6    Fang, F.7    Chang, Y.8
  • 157
    • 84930915491 scopus 로고    scopus 로고
    • Estrogen-related receptor alpha and mitochondria: Tale of the titans
    • Ranhotra HS. Estrogen-related receptor alpha and mitochondria: tale of the titans. J Recept Signal Transduct Res. 2014;15:1-5.
    • (2014) J Recept Signal Transduct Res , vol.15 , pp. 1-5
    • Ranhotra, H.S.1
  • 160
    • 84906853694 scopus 로고    scopus 로고
    • Metabolic modulators of the exercise response: Doping control analysis of an agonist of the peroxisome proliferatoractivated receptor δ (GW501516) and 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR)
    • Pokrywka A, Cholbinski P, Kaliszewski P, Kowalczyk K, Konczak D, Zembron-Lacny A. Metabolic modulators of the exercise response: doping control analysis of an agonist of the peroxisome proliferatoractivated receptor δ (GW501516) and 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR). J Physiol Pharmacol. 2014;65:469-476.
    • (2014) J Physiol Pharmacol , vol.65 , pp. 469-476
    • Pokrywka, A.1    Cholbinski, P.2    Kaliszewski, P.3    Kowalczyk, K.4    Konczak, D.5    Zembron-Lacny, A.6
  • 161
    • 0037112441 scopus 로고    scopus 로고
    • Estrogen-related receptor alpha and estrogen-related receptor gamma associate with unfavorable and favorable biomarkers, respectively, in human breast cancer
    • Ariazi EA, Clark GM, Mertz JE. Estrogen-related receptor alpha and estrogen-related receptor gamma associate with unfavorable and favorable biomarkers, respectively, in human breast cancer. Cancer Res. 2002;62:6510-6518.
    • (2002) Cancer Res , vol.62 , pp. 6510-6518
    • Ariazi, E.A.1    Clark, G.M.2    Mertz, J.E.3
  • 162
    • 3042699992 scopus 로고    scopus 로고
    • Estrogen-related receptor alpha in human breast carcinoma as a potent prognostic factor
    • Suzuki T, Miki Y, Moriya T, Shimada N, Ishida T, Hirakawa H, Ohuchi N, Sasano H. Estrogen-related receptor alpha in human breast carcinoma as a potent prognostic factor. Cancer Res. 2004;64:4670-4676. doi: 10.1158/0008-5472.CAN-04-0250.
    • (2004) Cancer Res , vol.64 , pp. 4670-4676
    • Suzuki, T.1    Miki, Y.2    Moriya, T.3    Shimada, N.4    Ishida, T.5    Hirakawa, H.6    Ohuchi, N.7    Sasano, H.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.