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Volumn 282, Issue 24, 1999, Pages 2340-2346

Effect of statins on risk of coronary disease. A meta-analysis of randomized controlled trials

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; CREATININE; LIPID; PLACEBO; STATIN;

EID: 0033596281     PISSN: 00987484     EISSN: None     Source Type: Journal    
DOI: 10.1001/jama.282.24.2340     Document Type: Review
Times cited : (1185)

References (45)
  • 1
    • 0027987849 scopus 로고
    • Randomized trial of cholesterol lowering in 4444 patients with coronary heart disease
    • Scandinavian Simvastatin Survival Study Group. Randomized trial of cholesterol lowering in 4444 patients with coronary heart disease. Lancet. 1994;344:1383-1389.
    • (1994) Lancet , vol.344 , pp. 1383-1389
  • 2
    • 0344653659 scopus 로고    scopus 로고
    • Cholesterol-lowering therapy in women and elderly patients with myocardial infarction or angina pectoris
    • Miettinen TA, Pyörälä K, Olsson AG, et al. Cholesterol-lowering therapy in women and elderly patients with myocardial infarction or angina pectoris. Circulation. 1997;96:4211-4218.
    • (1997) Circulation , vol.96 , pp. 4211-4218
    • Miettinen, T.A.1    Pyörälä, K.2    Olsson, A.G.3
  • 3
    • 0028883828 scopus 로고
    • Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia
    • Shepherd J, Cobbe SM, Ford I, et al. Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. N Engl J Med. 1995;333:1301-1307.
    • (1995) N Engl J Med. , vol.333 , pp. 1301-1307
    • Shepherd, J.1    Cobbe, S.M.2    Ford, I.3
  • 5
    • 17144464838 scopus 로고    scopus 로고
    • Effect of pravastatin on cardiovascular events in women after myocardial infarction
    • Lewis SJ, Sacks FM, Mitchell JS, et al. Effect of pravastatin on cardiovascular events in women after myocardial infarction. J Am Coll Cardiol. 1998;32:140-146.
    • (1998) J Am Coll Cardiol. , vol.32 , pp. 140-146
    • Lewis, S.J.1    Sacks, F.M.2    Mitchell, J.S.3
  • 6
    • 14444271787 scopus 로고    scopus 로고
    • Effect of pravastatin on cardiovascular events in older patients with myocardial infarction and cholesterol levels in the average range
    • Lewis SJ, Moye LA, Sacks FM, et al. Effect of pravastatin on cardiovascular events in older patients with myocardial infarction and cholesterol levels in the average range. Ann Intern Med. 1998;129:681-689.
    • (1998) Ann Intern Med. , vol.129 , pp. 681-689
    • Lewis, S.J.1    Moye, L.A.2    Sacks, F.M.3
  • 7
    • 0032572086 scopus 로고    scopus 로고
    • Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: Results of AFCAPS/TexCAPS
    • Downs JR, Clearfield M, Weis S, et al. Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. JAMA. 1998;279:1615-1622.
    • (1998) JAMA , vol.279 , pp. 1615-1622
    • Downs, J.R.1    Clearfield, M.2    Weis, S.3
  • 8
    • 0032487931 scopus 로고    scopus 로고
    • Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels
    • Long-term Intervention With Pravastatin in Ischaemic Disease (LIPID) Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med. 1998;339: 1349-1357.
    • (1998) N Engl J Med. , vol.339 , pp. 1349-1357
  • 9
    • 0343273397 scopus 로고
    • Cholesterol, diastolic blood pressure and stroke
    • Prospective Studies Collaboration. Cholesterol, diastolic blood pressure and stroke. Lancet. 1995;346: 1647-1653.
    • (1995) Lancet , vol.346 , pp. 1647-1653
  • 10
    • 0030022929 scopus 로고    scopus 로고
    • Guidelines for using serum cholesterol, high-density lipoprotein cholesterol, and triglyceride levels as screening tests for preventing coronary heart disease
    • American College of Physicians. Guidelines for using serum cholesterol, high-density lipoprotein cholesterol, and triglyceride levels as screening tests for preventing coronary heart disease. Ann Intern Med. 1996;124:515-517.
    • (1996) Ann Intern Med. , vol.124 , pp. 515-517
  • 11
    • 0030945970 scopus 로고    scopus 로고
    • Adherence to national cholesterol education program treatment goals in postmenopausal women with heart disease
    • Schrott HG, Bittner V, Vittinghott E, et al. Adherence to National Cholesterol Education Program treatment goals in postmenopausal women with heart disease. JAMA. 1997;277:1281-1286.
    • (1997) JAMA , vol.277 , pp. 1281-1286
    • Schrott, H.G.1    Bittner, V.2    Vittinghott, E.3
  • 12
    • 0025737883 scopus 로고
    • Analysis and interpretation of treatment effects in subgroups of patients in randomized clinical trials
    • Vusuf S, Wittes J, Probstfield J, Tyroler HA. Analysis and interpretation of treatment effects in subgroups of patients in randomized clinical trials. JAMA. 1991;266:93-98.
    • (1991) JAMA , vol.266 , pp. 93-98
    • Vusuf, S.1    Wittes, J.2    Probstfield, J.3    Tyroler, H.A.4
  • 13
    • 0029047727 scopus 로고
    • Protocol for a prospective collaborative overview of all current and planned randomized trials of cholesterol treatment regimens
    • Cholesterol treatment Trialists' Collaboration. Protocol for a prospective collaborative overview of all current and planned randomized trials of cholesterol treatment regimens. Am J Cardiol. 1995;75:1130-1134.
    • (1995) Am J Cardiol. , vol.75 , pp. 1130-1134
  • 14
    • 0030802435 scopus 로고    scopus 로고
    • Cholesterol lowering with statin drugs, risk of stroke, and total mortality
    • Hebert PR, Gaziano JM, Chan KS, Hennekens CH. Cholesterol lowering with statin drugs, risk of stroke, and total mortality. JAMA. 1997;278:313-321.
    • (1997) JAMA , vol.278 , pp. 313-321
    • Hebert, P.R.1    Gaziano, J.M.2    Chan, K.S.3    Hennekens, C.H.4
  • 16
    • 0025726579 scopus 로고
    • Prevention of restenosis by lovastatin after successful coronary angioplasty
    • Sahni R, Maniet AR, Gerardo V, Banks VS. Prevention of restenosis by lovastatin after successful coronary angioplasty. Am Heart J. 1991;121:1600-1608.
    • (1991) Am Heart J. , vol.121 , pp. 1600-1608
    • Sahni, R.1    Maniet, A.R.2    Gerardo, V.3    Banks, V.S.4
  • 17
    • 0026088892 scopus 로고
    • Expanded Clinical Evaluation of Lovastatin (EXCEL) study results, I
    • Bradford RH, Shear CL, Chremos AN, et al. Expanded Clinical Evaluation of Lovastatin (EXCEL) study results, I. Arch Intern Med. 1991;151:43-49.
    • (1991) Arch Intern Med. , vol.151 , pp. 43-49
    • Bradford, R.H.1    Shear, C.L.2    Chremos, A.N.3
  • 18
    • 0027488722 scopus 로고
    • Coronary angiographic changes with lovastatin therapy
    • Blankenhorn DH, Azen SP, Kramsch DM, et al. Coronary angiographic changes with lovastatin therapy. Ann Intern Med. 1993;119:969-976.
    • (1993) Ann Intern Med. , vol.119 , pp. 969-976
    • Blankenhorn, D.H.1    Azen, S.P.2    Kramsch, D.M.3
  • 19
    • 0026022180 scopus 로고
    • Once-daily pravastatin in patients with primary hypercholesterolemia
    • Jones PH, Farmer JA, Cressman MD, et al. Once-daily pravastatin in patients with primary hypercholesterolemia. Clin Cardiol. 1991;14:146-151.
    • (1991) Clin Cardiol. , vol.14 , pp. 146-151
    • Jones, P.H.1    Farmer, J.A.2    Cressman, M.D.3
  • 20
    • 0027507820 scopus 로고
    • Effects of pravastatin in patients with serum total cholesterol levels from 5.2 to 7.8 mmol/ liter (200 to 300 mg/dl) plus two additional atherosclerotic risk factors
    • The Pravastatin Multinational Study Group for Cardiac Risk Factors. Effects of pravastatin in patients with serum total cholesterol levels from 5.2 to 7.8 mmol/ liter (200 to 300 mg/dl) plus two additional atherosclerotic risk factors. Am J Cardiol. 1993;72:1031-1037.
    • (1993) Am J Cardiol. , vol.72 , pp. 1031-1037
  • 21
    • 0028282508 scopus 로고
    • Efficacy and safety of pravastatin in the long-term treatment of elderly patients with hypercholesterolemia
    • Santinga JT, Rosman HS, Rubenfire M, et al. Efficacy and safety of pravastatin in the long-term treatment of elderly patients with hypercholesterolemia. Am J Med. 1994;96:509-515.
    • (1994) Am J Med. , vol.96 , pp. 509-515
    • Santinga, J.T.1    Rosman, H.S.2    Rubenfire, M.3
  • 23
    • 0028020982 scopus 로고
    • Effect of lovastatin on early carotid atherosclerosis and cardiovascular events
    • Furberg CD, Adams HP, Applegate WB, et al. Effect of lovastatin on early carotid atherosclerosis and cardiovascular events. Circulation. 1994;90:1679-1687.
    • (1994) Circulation. , vol.90 , pp. 1679-1687
    • Furberg, C.D.1    Adams, H.P.2    Applegate, W.B.3
  • 24
    • 0028322993 scopus 로고
    • Three-year follow-up of the oxford cholesterol study
    • Keech A, Collins R, MacMahon S, et al. Three-year follow-up of the Oxford Cholesterol Study. Eur Heart J. 1994;15:255-269.
    • (1994) Eur Heart J. , vol.15 , pp. 255-269
    • Keech, A.1    Collins, R.2    MacMahon, S.3
  • 25
    • 0028267313 scopus 로고
    • Effects of monotherapy with an HMG-CoA reductase inhibitor on the progression of coronary arteriography
    • Waters D, Higginson L, Gladstone P, et al. Effects of monotherapy with an HMG-CoA reductase inhibitor on the progression of coronary arteriography. Circulation. 1994;89:959-968.
    • (1994) Circulation , vol.89 , pp. 959-968
    • Waters, D.1    Higginson, L.2    Gladstone, P.3
  • 26
    • 0028113715 scopus 로고
    • Lack of effect of lovastatin on restenosis after coronary angioplasty
    • Weintraub WS, Boccuzzi SJ, Klein JL, et al. Lack of effect of lovastatin on restenosis after coronary angioplasty. N Engl J Med 1994;331:1331-1337.
    • (1994) N Engl J Med , vol.331 , pp. 1331-1337
    • Weintraub, W.S.1    Boccuzzi, S.J.2    Klein, J.L.3
  • 27
    • 0029050796 scopus 로고
    • Effects of lipid lowering by pravastatin on progression and regression of coronary artery disease in symptomatic men with normal to moderately elevated serum cholesterol levels
    • Jukema JW, Bruschke AVG, van Boven ADJ, et al. Effects of lipid lowering by pravastatin on progression and regression of coronary artery disease in symptomatic men with normal to moderately elevated serum cholesterol levels. Circulation. 1995;91:2528-2540.
    • (1995) Circulation , vol.91 , pp. 2528-2540
    • Jukema, J.W.1    Bruschke, A.V.G.2    Van Boven, A.D.J.3
  • 28
    • 0028849703 scopus 로고
    • Pravastatin limitation of atherosclerosis in the coronary arteries (PLAC 1)
    • Pitt B, Mancini GBJ, Ellis SG, et al. Pravastatin limitation of atherosclerosis in the coronary arteries (PLAC 1). J Am Coll Cardiol. 1995;26:1133-1139.
    • (1995) J Am Coll Cardiol. , vol.26 , pp. 1133-1139
    • Pitt, B.1    Mancini, G.B.J.2    Ellis, S.G.3
  • 29
    • 0028910703 scopus 로고
    • Pravastatin, lipids, and atherosclerosis in the carotid arteries (PLAC-II)
    • Crouse JR, Byington RP, Bond MG, et al. Pravastatin, lipids, and atherosclerosis in the Carotid Arteries (PLAC-II). Am J Cardiol. 1995;75:455-459.
    • (1995) Am J Cardiol. , vol.75 , pp. 455-459
    • Crouse, J.R.1    Byington, R.P.2    Bond, M.G.3
  • 30
    • 0029096765 scopus 로고
    • Kuopio Atherosclerosis Prevention Study (KAPS)
    • Salonen R, Nyyyssonen K, Porkkala E, et al. Kuopio Atherosclerosis Prevention Study (KAPS). Circulation. 1995;92:1758-1764.
    • (1995) Circulation , vol.92 , pp. 1758-1764
    • Salonen, R.1    Nyyyssonen, K.2    Porkkala, E.3
  • 31
    • 0030036537 scopus 로고    scopus 로고
    • Changes in cardiovascular risk factors by combined pharmacological and nonpharmacological strategies
    • Lindholm LH, Ekbom T, Dash C, Isaacsson A, Schersten B. Changes in cardiovascular risk factors by combined pharmacological and nonpharmacological strategies. J Intern Med. 1996;240:13-22.
    • (1996) J Intern Med. , vol.240 , pp. 13-22
    • Lindholm, L.H.1    Ekbom, T.2    Dash, C.3    Isaacsson, A.4    Schersten, B.5
  • 32
    • 8244249463 scopus 로고    scopus 로고
    • Pravastatin reduces carotid intima-media thickness progression in an asymptomatic hypercholesterolemic mediterranean population
    • Mercuri M, Bond MG, Sirtori CR, et al. Pravastatin reduces carotid intima-media thickness progression in an asymptomatic hypercholesterolemic Mediterranean population. Am J Med. 1996;101:627-634.
    • (1996) Am J Med. , vol.101 , pp. 627-634
    • Mercuri, M.1    Bond, M.G.2    Sirtori, C.R.3
  • 33
    • 0030967489 scopus 로고    scopus 로고
    • Comparison on one-year efficacy and safety of atorvastatin versus lovastatin in primary hypercholesterolemia
    • Davidson M, McKenny J, Stein E, et al. Comparison on one-year efficacy and safety of atorvastatin versus lovastatin in primary hypercholesterolemia. Am J Cardiol. 1997;79:1475-1481.
    • (1997) Am J Cardiol. , vol.79 , pp. 1475-1481
    • Davidson, M.1    McKenny, J.2    Stein, E.3
  • 34
    • 0030988666 scopus 로고    scopus 로고
    • Effect of pravastatin (10 mg/day) on progression of coronary atherosclerosis in patients with serum total cholesterol levels from 160 to 220 mg/dl and angiographically documented coronary artery disease
    • Tamura A, Mikuriya Y, Nasu M. Effect of pravastatin (10 mg/day) on progression of coronary atherosclerosis in patients with serum total cholesterol levels from 160 to 220 mg/dl and angiographically documented coronary artery disease. Am J Cardiol. 1997;79:893-896.
    • (1997) Am J Cardiol. , vol.79 , pp. 893-896
    • Tamura, A.1    Mikuriya, Y.2    Nasu, M.3
  • 35
    • 9844260076 scopus 로고    scopus 로고
    • Effect of pravastatin on angiographic restenosis after coronary balloon angioplasty
    • Bertrand ME, McFadden EP, Fruchart JC, et al. Effect of pravastatin on angiographic restenosis after coronary balloon angioplasty. J Am Coll Cardiol. 1997; 30:863-869.
    • (1997) J Am Coll Cardiol. , vol.30 , pp. 863-869
    • Bertrand, M.E.1    McFadden, E.P.2    Fruchart, J.C.3
  • 36
    • 0005542912 scopus 로고    scopus 로고
    • The effect of simvastatin on progression of coronary artery disease
    • Bestehorn HP, Rensing UFE, Roskamm H, et al. The effect of simvastatin on progression of coronary artery disease. Eur Heart J. 1997;18:226-234.
    • (1997) Eur Heart J. , vol.18 , pp. 226-234
    • Bestehorn, H.P.1    Rensing, U.F.E.2    Roskamm, H.3
  • 37
    • 0027981582 scopus 로고
    • Effect of simvastatin on coronary atheroma
    • MAAS Investigators. Effect of simvastatin on coronary atheroma. Lancet. 1994;344:633-638.
    • (1994) Lancet , vol.344 , pp. 633-638
  • 38
    • 0029978197 scopus 로고    scopus 로고
    • Reduction in carotid arterial wall thickness using lovastatin and dietary therapy
    • Hodis HN, Mack WJ, LaBree L, et al. Reduction in carotid arterial wall thickness using lovastatin and dietary therapy. Ann Intern Med. 1996;124:548-556.
    • (1996) Ann Intern Med. , vol.124 , pp. 548-556
    • Hodis, H.N.1    Mack, W.J.2    LaBree, L.3
  • 39
    • 0031030620 scopus 로고    scopus 로고
    • The effect of aggressive lowering of low-density lipoprotein cholesterol levels and low-dose anticoagulation on obstructive changes in saphenousvein coronary-artery bypass grafts
    • Post Coronary Artery Bypass Graft Trial Investigators. The effect of aggressive lowering of low-density lipoprotein cholesterol levels and low-dose anticoagulation on obstructive changes in saphenousvein coronary-artery bypass grafts. N Engl J Med. 1997; 336:153-162.
    • (1997) N Engl J Med. , vol.336 , pp. 153-162
  • 40
    • 0000173036 scopus 로고
    • Measures of effect size for categorical data
    • Cooper H, Hedges LV, eds. New York, NV: Russell Sage Foundation
    • Fleiss JL. Measures of effect size for categorical data. In: Cooper H, Hedges LV, eds. The Handbook of Research Synthesis. New York, NV: Russell Sage Foundation; 1994:245-260.
    • (1994) The Handbook of Research Synthesis , pp. 245-260
    • Fleiss, J.L.1
  • 41
    • 0029918188 scopus 로고    scopus 로고
    • Rationale and design for the Antihypertensive and Lipid Lowering Treatment of Prevent Heart Attack Trial (ALLHAT)
    • Davis BR, Cutler JA, Gordon DJ, et al. Rationale and design for the Antihypertensive and Lipid Lowering Treatment of Prevent Heart Attack Trial (ALLHAT). Am J Hypertens. 1996;9:342-360.
    • (1996) Am J Hypertens. , vol.9 , pp. 342-360
    • Davis, B.R.1    Cutler, J.A.2    Gordon, D.J.3
  • 42
    • 0343545507 scopus 로고    scopus 로고
    • Unresolved issues: Unanswered questions: Proceedings from the amstel hotel satellite symposium: Controversies in the determination of cardiovascular therapy
    • August 22-26, Vienna, Austria. In press
    • LaRosa JC. Unresolved Issues: Unanswered Questions: Proceedings from the Amstel Hotel Satellite Symposium: Controversies in the Determination of Cardiovascular Therapy. XXth Congress of the European Society of Cardiology; August 22-26, 1998; Vienna, Austria. In press.
    • (1998) XXth Congress of the European Society of Cardiology
    • LaRosa, J.C.1
  • 43
    • 0343545508 scopus 로고    scopus 로고
    • The PROSPER design: A prospective study of pravastatin in the elderly at risk
    • May 5-8, Glasgow, Scotland
    • Gaw A, Blauw GJ, Shepherd J, Murphy M. The PROSPER design: a prospective study of pravastatin in the elderly at risk. Paper presented at: International Congress on Vascular Prevention; May 5-8, 1998; Glasgow, Scotland.
    • (1998) International Congress on Vascular Prevention
    • Gaw, A.1    Blauw, G.J.2    Shepherd, J.3    Murphy, M.4
  • 44
    • 0032547326 scopus 로고    scopus 로고
    • Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in post-menopausal women
    • Hulley S, Grady D, Bush T, et al, for the Heart and Estrogen/Progestin Replacement Study (HERS) Research Group. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in post-menopausal women. JAMA. 1998;280:605-613.
    • (1998) JAMA , vol.280 , pp. 605-613
    • Hulley, S.1    Grady, D.2    Bush, T.3
  • 45
    • 0030964475 scopus 로고    scopus 로고
    • Cholesterol management in women and the elderly
    • LaRosa JC. Cholesterol management in women and the elderly. J Intern Med. 1997;157:961-968.
    • (1997) J Intern Med. , vol.157 , pp. 961-968
    • LaRosa, J.C.1


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