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Volumn 23, Issue 15, 2015, Pages 4324-4332

One-pot synthesis of human metabolites of SAR548304 by fungal peroxygenases

(10) Kiebist, Jan b Holla, Wolfgang a Heidrich, Johannes a Poraj Kobielska, Marzena c Sandvoss, Martin a Simonis, Reiner a Gröbe, Glenn b Atzrodt, Jens a Hofrichter, Martin c Scheibner, Katrin b

a SANOFI AVENTIS DEUTSCHLAND GMBH (Germany)

b Faculty of Sciences (Germany)

c DRESDEN UNIVERSITY OF TECHNOLOGY (Germany)

Author keywords

Drug metabolite synthesis; EC 1.11.2.1; N dealkylation; Unspecific peroxygenase; UPO

Indexed keywords

ACETONITRILE; BILE ACID SEQUESTRANT; DRUG METABOLITE; FUNGAL ENZYME; N MONO DESMETHYL METABOLITE; N,N DI DESMETHYL METABOLITE; OXYGENASE; PALLADIUM; SAR 548304; UNCLASSIFIED DRUG; UNSPECIFIC PEROXYGENASE; CARBANILAMIDE DERIVATIVE; GLUCOSAMINE; HETEROCYCLIC COMPOUND; HYDROGEN PEROXIDE; MIXED FUNCTION OXIDASE; PEROXYGENASE; SAR548304;

ARTICLE; CATALYSIS; CATALYST; DEALKYLATION; DRUG METABOLISM; DRUG STRUCTURE; DRUG SYNTHESIS; MARASMIUS; MARASMIUS ROTULA; ONE POT SYNTHESIS; ANALOGS AND DERIVATIVES; CHEMISTRY; ENZYMOLOGY; HUMAN; METABOLISM; SYNTHESIS;

MARASMIUS ROTULA;

CATALYSIS; GLUCOSAMINE; HETEROCYCLIC COMPOUNDS; HUMANS; HYDROGEN PEROXIDE; MARASMIUS; MIXED FUNCTION OXYGENASES; PALLADIUM; PHENYLUREA COMPOUNDS;

EID: 84937526251 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2015.06.035 Document Type: Article

Times cited : (21)

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