Combined effects on selectivity in Fe-catalyzed methylene oxidation

Science

Volumn 327, Issue 5965, 2010, Pages 533-571

  Chen, Mark S ^a   White, M Christina ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBENE; IRON; CARBON; COORDINATION COMPOUND; HYDROCARBON; HYDROGEN; HYDROGEN PEROXIDE;

ALIPHATIC HYDROCARBON; BIOCHEMISTRY; CATALYST; CHEMICAL BONDING; ENZYME ACTIVITY; OXIDATION;

ARTICLE; CATALYSIS; CHEMICAL BOND; CHEMICAL STRUCTURE; HYDROXYLATION; OXIDATION; PRIORITY JOURNAL; CHEMICAL MODEL; CHEMISTRY; OXIDATION REDUCTION REACTION; PHYSICAL CHEMISTRY;

CARBON; CATALYSIS; COORDINATION COMPLEXES; HYDROCARBONS; HYDROGEN; HYDROGEN PEROXIDE; IRON; MODELS, CHEMICAL; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; PHYSICOCHEMICAL PROCESSES;

EID: 75749110908     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1183602     Document Type: Article

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35. Dedicated to Professor Eric N. Jacobsen on his 50th birthday for his inspirational work on selective oxidations. We gratefully acknowledge R. J. Pakula for performing gas chromatography experiments toward elucidating the steric effects on oxidation site selectivity; M. A. Bigi, D. J. Covell, and E. M. Stang for helpful discussions and checking our spectroscopic data; and S. A. Reed for helpful discussions and checking our experimental procedure. M.S.C. was a Harvard University graduate student who completed his doctoral work with M.C.W. at the University of Illinois at Urbana-Champaign. This work was submitted to M.S.C.'s committee as part of his thesis on 28 August 2009 and was presented by M.C.W. at the Welch Symposium on 27 October 2009. We are grateful to the A. P. Sloan Foundation, the Camille and Henry Dreyfus Foundation, Bristol-Myers Squibb, Pfizer, Abbott, and the University of Illinois for financial support. M.S.C. is a 2008 Bristol-Myers Squibb Graduate Fellow in Synthetic Organic Chemistry. A U.S. patent on "Selective Aliphatic C-H Oxidation" is pending (application 12/245,086).