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Volumn 2012, Issue 3, 2012, Pages 257-278

The synthesis of selected phase II metabolites - O-glucuronides and sulfates of drug development candidates

Author keywords

Acyl glucuronides; Glucuronides; Metabolite analysis; Phase II metabolites; Sulfates

Indexed keywords


EID: 84879332148     PISSN: 1551-7012     EISSN: 15517004     Source Type: Journal    
DOI: 10.3998/ark.5550190.0013.319     Document Type: Article
Times cited : (7)

References (79)
  • 20
    • 0032054655 scopus 로고    scopus 로고
    • For review of glucuronidation methods and the preparation of the most common glucuronate glycosyl donors see
    • For review of glucuronidation methods and the preparation of the most common glucuronate glycosyl donors see Stachulski, A. V.; G. Jenkins, G. Natural Product Reports 1998, 173.
    • (1998) Natural Product Reports , pp. 173
    • Stachulski, A.V.1    G Jenkins, G.2
  • 43
    • 84884194985 scopus 로고    scopus 로고
    • Boisnard S., Sanofi, Chilly-Mazarin, personal note
    • Boisnard S., Sanofi, Chilly-Mazarin, personal note.
  • 63
    • 84884174905 scopus 로고    scopus 로고
    • note
    • Methyl 1-bromo-1-deoxy-2,3,4-tri-O-acetyl- α-D-glucopyranuronate 2b was purchased from Fluka, the corresponding benzoyl and pivaloyl derivatives were prepared in three steps from D-glucuronolactone according to Ref. 34.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.