메뉴 건너뛰기




Volumn 83, Issue , 2015, Pages 275-282

Supercritical CO2 extraction of oil, fatty acids and flavonolignans from milk thistle seeds: Evaluation of their antioxidant and cytotoxic activities in Caco-2 cells

Author keywords

Caco 2 carcinoma cells; Fatty acids; Flavonolignans; Milk thistle seeds; Oil; Supercritical CO2

Indexed keywords

BETA CAROTENE; FATTY ACID; FLAVONOLIGNAN; LINOLEIC ACID; OIL; OLEIC ACID; PALMITIC ACID; POLYPHENOL; SILIBININ; SILICRISTIN; SILIDIANIN; SILYMARIN; TAXIFOLIN; UNSATURATED FATTY ACID; ANTINEOPLASTIC AGENT; ANTIOXIDANT; FOOD ADDITIVE; VEGETABLE OIL;

EID: 84937203854     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2015.07.006     Document Type: Article
Times cited : (49)

References (45)
  • 1
    • 0032543406 scopus 로고    scopus 로고
    • Skin cancer chemopreventive effects of a flavonoid antioxidant silymarin are mediated via impairment of receptor tyrosine kinase signaling and perturbation in cell cycle progression
    • Ahmad N., Gali H., Javed S., Agarwal R. Skin cancer chemopreventive effects of a flavonoid antioxidant silymarin are mediated via impairment of receptor tyrosine kinase signaling and perturbation in cell cycle progression. Biochem. Biophys. Res. Commun. 1998, 247:294-301.
    • (1998) Biochem. Biophys. Res. Commun. , vol.247 , pp. 294-301
    • Ahmad, N.1    Gali, H.2    Javed, S.3    Agarwal, R.4
  • 2
    • 84921509002 scopus 로고    scopus 로고
    • New approaches for the use of non-conventional cell disruption technologies to extract potential food additives and nutraceuticals from microalgae
    • Barba F.J., Grimi N., Vorobiev E. New approaches for the use of non-conventional cell disruption technologies to extract potential food additives and nutraceuticals from microalgae. Food Eng. Rev. 2014, 7:45-62.
    • (2014) Food Eng. Rev. , vol.7 , pp. 45-62
    • Barba, F.J.1    Grimi, N.2    Vorobiev, E.3
  • 3
    • 84902147122 scopus 로고    scopus 로고
    • The consumer's perception of artificial food additives: influences on acceptance, risk and benefit perceptions
    • Bearth A., Cousin M.-E., Siegrist M. The consumer's perception of artificial food additives: influences on acceptance, risk and benefit perceptions. Food Qual. Prefer 2014, 38:14-23.
    • (2014) Food Qual. Prefer , vol.38 , pp. 14-23
    • Bearth, A.1    Cousin, M.-E.2    Siegrist, M.3
  • 5
    • 84937228085 scopus 로고    scopus 로고
    • Silibinin and STAT3: a natural way of targeting transcription factors for cancer therapy
    • Bosch-Barrera J., Menendez J.A. Silibinin and STAT3: a natural way of targeting transcription factors for cancer therapy. Cancer Treat. Rev. 2015, 10.1016/j.ctrv.2015.04.008.
    • (2015) Cancer Treat. Rev.
    • Bosch-Barrera, J.1    Menendez, J.A.2
  • 7
    • 84870460057 scopus 로고    scopus 로고
    • Absorption and metabolism of milk thistle flavanolignans in humans
    • Calani L., Brighenti F., Bruni R., Del Rio D. Absorption and metabolism of milk thistle flavanolignans in humans. Phytomedicine 2012, 20:40-46.
    • (2012) Phytomedicine , vol.20 , pp. 40-46
    • Calani, L.1    Brighenti, F.2    Bruni, R.3    Del Rio, D.4
  • 8
    • 84925584435 scopus 로고    scopus 로고
    • Extraction of oil and silybin compounds from milk thistle seeds using supercritical carbon dioxide
    • Celik H.T., Guru M. Extraction of oil and silybin compounds from milk thistle seeds using supercritical carbon dioxide. J. Supercrit. Fluids 2015, 100:105-109.
    • (2015) J. Supercrit. Fluids , vol.100 , pp. 105-109
    • Celik, H.T.1    Guru, M.2
  • 9
    • 84864359629 scopus 로고    scopus 로고
    • Green extraction of natural products: concept and principles
    • Chemat F., Vian M.A., Cravotto G. Green extraction of natural products: concept and principles. Int. J. Mol. Sci. 2012, 13(7):8615-8627.
    • (2012) Int. J. Mol. Sci. , vol.13 , Issue.7 , pp. 8615-8627
    • Chemat, F.1    Vian, M.A.2    Cravotto, G.3
  • 10
    • 3142765979 scopus 로고    scopus 로고
    • Silibinin inhibits the invasion of human lung cancer cells via decreased productions of urokinase-plasminogen activator and matrix metalloproteinase-2
    • Chu S.-C., Chiou H.-L., Chen P.-H., Yang S.-F., Hsieh Y.-S. Silibinin inhibits the invasion of human lung cancer cells via decreased productions of urokinase-plasminogen activator and matrix metalloproteinase-2. Mol. Carcinog. 2004, 40:143-149.
    • (2004) Mol. Carcinog. , vol.40 , pp. 143-149
    • Chu, S.-C.1    Chiou, H.-L.2    Chen, P.-H.3    Yang, S.-F.4    Hsieh, Y.-S.5
  • 11
    • 84861873002 scopus 로고    scopus 로고
    • Response surface optimization of hemp seed (Cannabis sativa L.) oil yield and oxidation stability by supercritical carbon dioxide extraction
    • Da Porto C., Voinovich D., Decorti D., Natolino A. Response surface optimization of hemp seed (Cannabis sativa L.) oil yield and oxidation stability by supercritical carbon dioxide extraction. J. Supercrit. Fluids 2012, 68:45-51.
    • (2012) J. Supercrit. Fluids , vol.68 , pp. 45-51
    • Da Porto, C.1    Voinovich, D.2    Decorti, D.3    Natolino, A.4
  • 12
    • 84940596339 scopus 로고    scopus 로고
    • The effects of conventional and non-conventional processing on glucosinolates and its derived forms, isothiocyanates: extraction, degradation, and applications
    • Deng Q., Zinoviadou K.G., Galanakis C.M., Orlien V., Grimi N., Vorobiev E., Lebovka N., Barba F.J. The effects of conventional and non-conventional processing on glucosinolates and its derived forms, isothiocyanates: extraction, degradation, and applications. Food Eng. Rev. 2014, 1-25. 10.1007/s12393-014-9104-9.
    • (2014) Food Eng. Rev. , pp. 1-25
    • Deng, Q.1    Zinoviadou, K.G.2    Galanakis, C.M.3    Orlien, V.4    Grimi, N.5    Vorobiev, E.6    Lebovka, N.7    Barba, F.J.8
  • 13
    • 84874394383 scopus 로고    scopus 로고
    • Omega-3 fatty acids and brain resistance to ageing and stress: body of evidence and possible mechanisms
    • Denisa I., Potierb B., Vancassela S., Heberdena C., Lavialle M. Omega-3 fatty acids and brain resistance to ageing and stress: body of evidence and possible mechanisms. Ageing Res. Rev. 2013, 12:579-594.
    • (2013) Ageing Res. Rev. , vol.12 , pp. 579-594
    • Denisa, I.1    Potierb, B.2    Vancassela, S.3    Heberdena, C.4    Lavialle, M.5
  • 14
    • 0034338605 scopus 로고    scopus 로고
    • Colouring our foods in the last and next millennium
    • Downham A., Collins P. Colouring our foods in the last and next millennium. Int. J. Food Sci. Technol. 2000, 35:5-22.
    • (2000) Int. J. Food Sci. Technol. , vol.35 , pp. 5-22
    • Downham, A.1    Collins, P.2
  • 15
    • 1842614155 scopus 로고    scopus 로고
    • Detailed studies on some lipids of Silybum marianum (L.) seed oil
    • El-Mallah M.H., El-Shami S.M., Hassanein M.M. Detailed studies on some lipids of Silybum marianum (L.) seed oil. Grasas Aceites 2003, 54:397-402.
    • (2003) Grasas Aceites , vol.54 , pp. 397-402
    • El-Mallah, M.H.1    El-Shami, S.M.2    Hassanein, M.M.3
  • 16
    • 84911911751 scopus 로고    scopus 로고
    • Silymarin induces cyclin D1 proteasomal degradation via its phosphorylation of threonine-286 in human colorectal cancer cells
    • Eo H.J., Park G.H., Song H.M., Lee J.W., Kim M.K., Lee M.H., Lee J.R., Koo J.S., Jeong J.B. Silymarin induces cyclin D1 proteasomal degradation via its phosphorylation of threonine-286 in human colorectal cancer cells. Int. Immunopharmacol. 2015, 24:1-6.
    • (2015) Int. Immunopharmacol. , vol.24 , pp. 1-6
    • Eo, H.J.1    Park, G.H.2    Song, H.M.3    Lee, J.W.4    Kim, M.K.5    Lee, M.H.6    Lee, J.R.7    Koo, J.S.8    Jeong, J.B.9
  • 17
    • 84915759710 scopus 로고    scopus 로고
    • Silymarin induces cell cycle arrest and apoptosis in ovarian cancer cells
    • Fan L., Ma Y., Liu Y., Zheng D., Huang G. Silymarin induces cell cycle arrest and apoptosis in ovarian cancer cells. Eur. J. Pharmacol. 2014, 743:79-88.
    • (2014) Eur. J. Pharmacol. , vol.743 , pp. 79-88
    • Fan, L.1    Ma, Y.2    Liu, Y.3    Zheng, D.4    Huang, G.5
  • 18
    • 0020709441 scopus 로고
    • 2 extraction of lipid-bearing materials and characterization of the products
    • 2 extraction of lipid-bearing materials and characterization of the products. J. Am. Oil Chem. Soc. 1984, 61:223-228.
    • (1984) J. Am. Oil Chem. Soc. , vol.61 , pp. 223-228
    • Friedrich, J.P.1    Pryde, E.H.2
  • 19
    • 0032571243 scopus 로고    scopus 로고
    • Supercritical carbon dioxide extraction of essential oils: modeling and simulation
    • Goodarznia I., Eikani M.H. Supercritical carbon dioxide extraction of essential oils: modeling and simulation. Chem. Eng. Sci. 1998, 53:1387-1395.
    • (1998) Chem. Eng. Sci. , vol.53 , pp. 1387-1395
    • Goodarznia, I.1    Eikani, M.H.2
  • 20
    • 0034884967 scopus 로고    scopus 로고
    • High pressure extraction of vitamin E-rich oil from Silybum marianum
    • Hadolin M., Skerget M., Knez Z., Bauman D. High pressure extraction of vitamin E-rich oil from Silybum marianum. Food Chem. 2001, 74:355-364.
    • (2001) Food Chem. , vol.74 , pp. 355-364
    • Hadolin, M.1    Skerget, M.2    Knez, Z.3    Bauman, D.4
  • 21
    • 35248818831 scopus 로고    scopus 로고
    • Flavonoid, silibinin, inhibits proliferation and promotes cell-cycle arrest of human colon cancer
    • Hogan F.S., Krishnegowda N.K., Mikhailova M., Kahlenberg M.S. Flavonoid, silibinin, inhibits proliferation and promotes cell-cycle arrest of human colon cancer. J. Surg. Res. 2007, 143:58-65.
    • (2007) J. Surg. Res. , vol.143 , pp. 58-65
    • Hogan, F.S.1    Krishnegowda, N.K.2    Mikhailova, M.3    Kahlenberg, M.S.4
  • 22
    • 84928894986 scopus 로고    scopus 로고
    • Silibinin, a natural flavonoid, induces autophagy via ROS-dependent mitochondrial dysfunction and loss of ATP involving BNIP3 in human MCF7 breast cancer cells
    • Jiang K., Wang W., Jin X., Wang Z., Ji Z., Meng G. Silibinin, a natural flavonoid, induces autophagy via ROS-dependent mitochondrial dysfunction and loss of ATP involving BNIP3 in human MCF7 breast cancer cells. Oncol. Rep. 2015, 33:2711-2718.
    • (2015) Oncol. Rep. , vol.33 , pp. 2711-2718
    • Jiang, K.1    Wang, W.2    Jin, X.3    Wang, Z.4    Ji, Z.5    Meng, G.6
  • 23
    • 84859001168 scopus 로고    scopus 로고
    • Optimization of enzymatic pretreatment for n-hexane extraction of oil from Silybum marianum seeds using response surface methodology
    • Li F., Yang L., Zhao T., Zhao J., Zou Y., Zou Y., Wu X. Optimization of enzymatic pretreatment for n-hexane extraction of oil from Silybum marianum seeds using response surface methodology. Food Bioprod. Process 2012, 90:87-94.
    • (2012) Food Bioprod. Process , vol.90 , pp. 87-94
    • Li, F.1    Yang, L.2    Zhao, T.3    Zhao, J.4    Zou, Y.5    Zou, Y.6    Wu, X.7
  • 25
    • 84939942887 scopus 로고    scopus 로고
    • Silymarin and hepatocellular carcinoma: a systematic, comprehensive, and critical review
    • Mastron J.K., Siveen K.S., Sethi G., Bishayee A. Silymarin and hepatocellular carcinoma: a systematic, comprehensive, and critical review. Anticancer. Drugs 2015, 10.1097/CAD.0000000000000211.
    • (2015) Anticancer. Drugs
    • Mastron, J.K.1    Siveen, K.S.2    Sethi, G.3    Bishayee, A.4
  • 26
    • 33845220524 scopus 로고    scopus 로고
    • Primary culture of rat hepatocytes in 96-well plates: effects of extracellular matrix configuration on cytochrome {P450} enzyme activity and inducibility, and its application in in vitro cytotoxicity screening
    • Mingoia R.T., Nabb D.L., Yang C.-H., Han X. Primary culture of rat hepatocytes in 96-well plates: effects of extracellular matrix configuration on cytochrome {P450} enzyme activity and inducibility, and its application in in vitro cytotoxicity screening. Toxicol. Vitr. 2007, 21:165-173.
    • (2007) Toxicol. Vitr. , vol.21 , pp. 165-173
    • Mingoia, R.T.1    Nabb, D.L.2    Yang, C.-H.3    Han, X.4
  • 27
    • 84937213510 scopus 로고
    • National Institute of Standards and Technologies (NIST), United States of America
    • NIST National Bureau of Standards 1986, National Institute of Standards and Technologies (NIST), United States of America.
    • (1986) National Bureau of Standards
  • 28
    • 84923168131 scopus 로고    scopus 로고
    • Pulsed electric field assisted extraction of nutritionally valuable compounds from microalgae Nannochloropsis spp. using the binary mixture of organic solvents and water
    • Parniakov O., Barba F.J., Grimi N., Marchal L., Jubeau S., Lebovka N., Vorobiev E. Pulsed electric field assisted extraction of nutritionally valuable compounds from microalgae Nannochloropsis spp. using the binary mixture of organic solvents and water. Innov. Food Sci. Emerg. Technol. 2014, 27:79-85.
    • (2014) Innov. Food Sci. Emerg. Technol. , vol.27 , pp. 79-85
    • Parniakov, O.1    Barba, F.J.2    Grimi, N.3    Marchal, L.4    Jubeau, S.5    Lebovka, N.6    Vorobiev, E.7
  • 29
    • 84928159251 scopus 로고    scopus 로고
    • Infusions of artichoke and milk thistle represent a good source of phenolic acids and flavonoids
    • Pereira C., Barros L., Carvalho A.M., Santos-Buelga C., Ferreira I.C.F.R. Infusions of artichoke and milk thistle represent a good source of phenolic acids and flavonoids. Food Funct. 2015, 6:56-62.
    • (2015) Food Funct. , vol.6 , pp. 56-62
    • Pereira, C.1    Barros, L.2    Carvalho, A.M.3    Santos-Buelga, C.4    Ferreira, I.C.F.R.5
  • 30
    • 0033046517 scopus 로고    scopus 로고
    • Determination of silymarine in the extract from the dried Silybum marianum fruits by high performance liquid chromatography and capillary electrophoresis
    • Quaglia M.G., Bossu E., Donati E., Mazzanti G., Brandt A. Determination of silymarine in the extract from the dried Silybum marianum fruits by high performance liquid chromatography and capillary electrophoresis. J. Pharm. Biomed. Anal. 1999, 19:435-442.
    • (1999) J. Pharm. Biomed. Anal. , vol.19 , pp. 435-442
    • Quaglia, M.G.1    Bossu, E.2    Donati, E.3    Mazzanti, G.4    Brandt, A.5
  • 31
    • 84861590719 scopus 로고    scopus 로고
    • Application of supercritical carbon dioxide to fruit and vegetables: extraction, processing, and preservation
    • Rawson A., Tiwari B.K., Brunton N., Brennan C., Cullen P.J., O'Donnell C.P. Application of supercritical carbon dioxide to fruit and vegetables: extraction, processing, and preservation. Food Rev. Int. 2012, 28:253-276.
    • (2012) Food Rev. Int. , vol.28 , pp. 253-276
    • Rawson, A.1    Tiwari, B.K.2    Brunton, N.3    Brennan, C.4    Cullen, P.J.5    O'Donnell, C.P.6
  • 33
    • 33749014401 scopus 로고    scopus 로고
    • Supercritical fluid extraction and fractionation of natural matter
    • Reverchon E., De Marco I. Supercritical fluid extraction and fractionation of natural matter. J. Supercrit. Fluids 2006, 38:146-166.
    • (2006) J. Supercrit. Fluids , vol.38 , pp. 146-166
    • Reverchon, E.1    De Marco, I.2
  • 35
    • 84925300111 scopus 로고    scopus 로고
    • Clean recovery of antioxidant compounds from plant foods, by-products and algae assisted by ultrasounds processing. Modeling approaches to optimize processing conditions
    • Rosello-Soto E., Galanakis C.M., Brncic M., Orlien V., Trujillo F.J., Mawson R., Knoerzer K., Tiwari B.K., Barba F.J. Clean recovery of antioxidant compounds from plant foods, by-products and algae assisted by ultrasounds processing. Modeling approaches to optimize processing conditions. Trends Food Sci. Technol. 2015, 42:134-149.
    • (2015) Trends Food Sci. Technol. , vol.42 , pp. 134-149
    • Rosello-Soto, E.1    Galanakis, C.M.2    Brncic, M.3    Orlien, V.4    Trujillo, F.J.5    Mawson, R.6    Knoerzer, K.7    Tiwari, B.K.8    Barba, F.J.9
  • 36
    • 0342470671 scopus 로고    scopus 로고
    • Liquid chromatographic-mass spectrometric analysis of supercritical-fluid extracts of rosemary plants
    • Senorans F.J., Ibanez E., Cavero S., Tabera J., Reglero G. Liquid chromatographic-mass spectrometric analysis of supercritical-fluid extracts of rosemary plants. J. Chromatogr. A 2000, 870:491-499.
    • (2000) J. Chromatogr. A , vol.870 , pp. 491-499
    • Senorans, F.J.1    Ibanez, E.2    Cavero, S.3    Tabera, J.4    Reglero, G.5
  • 37
    • 0042807487 scopus 로고    scopus 로고
    • Silibinin induces growth inhibition and apoptotic cell death in human lung carcinoma cells
    • Sharma G., Singh R.P., Chan D.C.F., Agarwal R. Silibinin induces growth inhibition and apoptotic cell death in human lung carcinoma cells. Anticancer Res. 2003, 23:2649-2655.
    • (2003) Anticancer Res. , vol.23 , pp. 2649-2655
    • Sharma, G.1    Singh, R.P.2    Chan, D.C.F.3    Agarwal, R.4
  • 38
    • 38849094730 scopus 로고    scopus 로고
    • Pretreatment of milk thistle seed to increase the silymarin yield: an alternative to petroleum ether defatting
    • Subramaniam S., Vaughn K., Carrier D.J., Clausen E.C. Pretreatment of milk thistle seed to increase the silymarin yield: an alternative to petroleum ether defatting. Bioresour. Technol. 2008, 99:2501-2506.
    • (2008) Bioresour. Technol. , vol.99 , pp. 2501-2506
    • Subramaniam, S.1    Vaughn, K.2    Carrier, D.J.3    Clausen, E.C.4
  • 39
    • 2642583226 scopus 로고    scopus 로고
    • Silibinin down-regulates prostate epithelium-derived ets transcription factor in LNCaP prostate cancer cells
    • Thelen P., Jarry H., Ringert R.-H., Wuttke W. Silibinin down-regulates prostate epithelium-derived ets transcription factor in LNCaP prostate cancer cells. Planta Med. 2004, 70:397-400.
    • (2004) Planta Med. , vol.70 , pp. 397-400
    • Thelen, P.1    Jarry, H.2    Ringert, R.-H.3    Wuttke, W.4
  • 40
    • 84927137189 scopus 로고    scopus 로고
    • U. S. Food and Drug Administration's (FDA) safety assessment of food ingredients
    • Thurmond T.S. U. S. Food and Drug Administration's (FDA) safety assessment of food ingredients. ACS Symp. Ser 2014, vol. 1162:91-95.
    • (2014) ACS Symp. Ser , vol.1162 , pp. 91-95
    • Thurmond, T.S.1
  • 41
    • 3242786628 scopus 로고    scopus 로고
    • Synergistic anti-cancer effects of silibinin with conventional cytotoxic agents doxorubicin, cisplatin and carboplatin against human breast carcinoma MCF-7 and MDA-MB468 cells
    • Tyagi A.K., Agarwal C., Chan D.C., Agarwal R. Synergistic anti-cancer effects of silibinin with conventional cytotoxic agents doxorubicin, cisplatin and carboplatin against human breast carcinoma MCF-7 and MDA-MB468 cells. Oncol. Rep. 2004, 11:493-499.
    • (2004) Oncol. Rep. , vol.11 , pp. 493-499
    • Tyagi, A.K.1    Agarwal, C.2    Chan, D.C.3    Agarwal, R.4
  • 44
    • 84859005880 scopus 로고    scopus 로고
    • The fatty acid compositions of Silybum marianum by GC-MS
    • Yin Q., Wang S., Nan J., L.S The fatty acid compositions of Silybum marianum by GC-MS. J. Yanbian Univ. Sci. 1998, 24:26-28.
    • (1998) J. Yanbian Univ. Sci. , vol.24 , pp. 26-28
    • Yin, Q.1    Wang, S.2    Nan, J.L.S3
  • 45
    • 0031921546 scopus 로고    scopus 로고
    • Anticarcinogenic effect of a flavonoid antioxidant, silymarin, in human breast cancer cells MDA-MB 468: induction of G1 arrest through an increase in Cip1/p21 concomitant with a decrease in kinase activity of cyclin dependent kinases and associated cyclins
    • Zi X., Feyes D.K., Agarwal R. Anticarcinogenic effect of a flavonoid antioxidant, silymarin, in human breast cancer cells MDA-MB 468: induction of G1 arrest through an increase in Cip1/p21 concomitant with a decrease in kinase activity of cyclin dependent kinases and associated cyclins. Clin. Cancer Res. 1998, 4:1055-1064.
    • (1998) Clin. Cancer Res. , vol.4 , pp. 1055-1064
    • Zi, X.1    Feyes, D.K.2    Agarwal, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.