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Volumn 70, Issue 5, 2004, Pages 397-400

Silibinin down-regulates prostate epithelium-derived ets transcription factor in LNCaP prostate cancer cells

Author keywords

Androgen receptor co activator; PDEF; Prostate cancer; PSA; Silibinin

Indexed keywords

ANDROGEN RECEPTOR; ANDROSTANOLONE; MESSENGER RNA; PROSTATE SPECIFIC ANTIGEN; SILIBININ; SILYBUM MARIANUM EXTRACT; TRANSCRIPTION FACTOR ETS 1;

EID: 2642583226     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-818965     Document Type: Article
Times cited : (36)

References (15)
  • 2
    • 0034126666 scopus 로고    scopus 로고
    • Expression of estrogen receptor (ER)-alpha and ER-beta in normal and malignant prostatic epithelial cells: Regulation by methylation and involvement in growth regulation
    • Lau KM, LaSpina M, Long J, Ho SM. Expression of estrogen receptor (ER)-alpha and ER-beta in normal and malignant prostatic epithelial cells: regulation by methylation and involvement in growth regulation. Cancer Res. 2000; 60: 3175-82
    • (2000) Cancer Res , vol.60 , pp. 3175-3182
    • Lau, K.M.1    LaSpina, M.2    Long, J.3    Ho, S.M.4
  • 3
    • 0036604473 scopus 로고    scopus 로고
    • Expression of estrogen receptor beta in the fetal, neonatal, and prepubertal human prostate
    • Adams JY, Leav I, Lau KM, Ho SM, Pflueger SM. Expression of estrogen receptor beta in the fetal, neonatal, and prepubertal human prostate. Prostate. 2002; 52: 69-81
    • (2002) Prostate , vol.52 , pp. 69-81
    • Adams, J.Y.1    Leav, I.2    Lau, K.M.3    Ho, S.M.4    Pflueger, S.M.5
  • 4
    • 0141953283 scopus 로고    scopus 로고
    • Silymarin is a selective estrogen receptor β (ERβ) agonist and has estrogenic effects in the metaphysis of the femur but no or antiestrogenic effects in the uterus of ovariectomized (ovx) rats
    • Seidlová-Wuttke D, Becker T, Christoffel V, Jarry H Wuttke W. Silymarin is a selective estrogen receptor β (ERβ) agonist and has estrogenic effects in the metaphysis of the femur but no or antiestrogenic effects in the uterus of ovariectomized (ovx) rats. J Steroid Biochem Mol Biol 2003; 86: 179-88
    • (2003) J Steroid Biochem Mol Biol , vol.86 , pp. 179-188
    • Seidlová-Wuttke, D.1    Becker, T.2    Christoffel, V.3    Jarry, H.4    Wuttke, W.5
  • 5
    • 0035253312 scopus 로고    scopus 로고
    • Detrimental effect of cancer preventive phytochemicals silymarin, genistein and epigallocatechin 3-gallate on epigenetic events in human prostate carcinoma DU145 cells
    • Bhatia N, Agarwal R. Detrimental effect of cancer preventive phytochemicals silymarin, genistein and epigallocatechin 3-gallate on epigenetic events in human prostate carcinoma DU145 cells. Prostate 2001; 46: 98-107
    • (2001) Prostate , vol.46 , pp. 98-107
    • Bhatia, N.1    Agarwal, R.2
  • 6
    • 0034667455 scopus 로고    scopus 로고
    • Silibinin up-regulates insulin-like growth factor-binding protein 3 expression and inhibits proliferation of androgen-independent prostate cancer cells
    • Zi X, Zhang J, Agarwal R, Pollak M. Silibinin up-regulates insulin-like growth factor-binding protein 3 expression and inhibits proliferation of androgen-independent prostate cancer cells. Cancer Res 2000; 60: 5617-20
    • (2000) Cancer Res , vol.60 , pp. 5617-5620
    • Zi, X.1    Zhang, J.2    Agarwal, R.3    Pollak, M.4
  • 7
    • 0033594891 scopus 로고    scopus 로고
    • Silibinin decreases prostate-specific antigen with cell growth inhibition via G1 arrest, leading to differentiation of prostate carcinoma cells: Implications for prostate cancer intervention
    • Zi X, Agarwal R. Silibinin decreases prostate-specific antigen with cell growth inhibition via G1 arrest, leading to differentiation of prostate carcinoma cells: implications for prostate cancer intervention. Proc Natl Acad Sci USA 1999; 96: 7490-5
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 7490-7495
    • Zi, X.1    Agarwal, R.2
  • 8
    • 0034812087 scopus 로고    scopus 로고
    • Silymarin inhibits function of the androgen receptor by reducing nuclear localization of the receptor in the human prostate cancer cell line LNCaP
    • Zhu W, Zhang JS, Young CY. Silymarin inhibits function of the androgen receptor by reducing nuclear localization of the receptor in the human prostate cancer cell line LNCaP. Carcinogenesis 2001; 22: 1399-403
    • (2001) Carcinogenesis , vol.22 , pp. 1399-1403
    • Zhu, W.1    Zhang, J.S.2    Young, C.Y.3
  • 9
    • 0033957171 scopus 로고    scopus 로고
    • PDEF, a novel prostate epithelium-specific ets transcription factor, interacts with the androgen receptor and activates prostate-specific antigen gene expression
    • Oettgen P, Finger E, Sun Z, Akbarali Y, Thamrongsak U, Boltax J et al. PDEF, a novel prostate epithelium-specific ets transcription factor, interacts with the androgen receptor and activates prostate-specific antigen gene expression. J Biol Chem 2000; 275: 1216-25
    • (2000) J Biol Chem , vol.275 , pp. 1216-1225
    • Oettgen, P.1    Finger, E.2    Sun, Z.3    Akbarali, Y.4    Thamrongsak, U.5    Boltax, J.6
  • 10
    • 0034802736 scopus 로고    scopus 로고
    • Prostate epithelium-derived Ets transcription factor mRNA is overexpressed in human breast tumors and is a candidate breast tumor marker and a breast tumor antigen
    • Ghadersohi A, Sood AK. Prostate epithelium-derived Ets transcription factor mRNA is overexpressed in human breast tumors and is a candidate breast tumor marker and a breast tumor antigen. Clin. Cancer Res 2001; 7: 2731-8
    • (2001) Clin Cancer Res , vol.7 , pp. 2731-2738
    • Ghadersohi, A.1    Sood, A.K.2
  • 11
    • 0027399391 scopus 로고
    • An improved strategy and a useful housekeeping gene for RNA analysis from formalin-fixed, paraffin-embedded tissues by PCR
    • Finke J, Fritzen R, Ternes P, Lange W, Dolken G. An improved strategy and a useful housekeeping gene for RNA analysis from formalin-fixed, paraffin-embedded tissues by PCR. Biotechniques 1993; 14: 448-53
    • (1993) Biotechniques , vol.14 , pp. 448-453
    • Finke, J.1    Fritzen, R.2    Ternes, P.3    Lange, W.4    Dolken, G.5
  • 12
    • 0042847060 scopus 로고    scopus 로고
    • Bax inhibitor-1 is overexpressed in prostate cancer and its specific down-regulation by RNA interference leads to cell death in human prostate carcinoma cells
    • Grzmil M, Thelen P, Hemmerlein B, Schweyer S, Voigt S, Mury D et al. Bax inhibitor-1 is overexpressed in prostate cancer and its specific down-regulation by RNA interference leads to cell death in human prostate carcinoma cells. Am J Pathol 2003; 163: 543-52
    • (2003) Am J Pathol , vol.163 , pp. 543-552
    • Grzmil, M.1    Thelen, P.2    Hemmerlein, B.3    Schweyer, S.4    Voigt, S.5    Mury, D.6
  • 13
    • 0036843213 scopus 로고    scopus 로고
    • Antiproliferative and apoptotic effects of silibinin in rat prostate cancer cells
    • Tyagi A, Bhatia N, Condon MS, Bosland MC, Agarwal C, Agarwal R. Antiproliferative and apoptotic effects of silibinin in rat prostate cancer cells. Prostate 2002; 53: 211-17
    • (2002) Prostate , vol.53 , pp. 211-217
    • Tyagi, A.1    Bhatia, N.2    Condon, M.S.3    Bosland, M.C.4    Agarwal, C.5    Agarwal, R.6
  • 14
    • 0037081280 scopus 로고    scopus 로고
    • NKX-3.1 interacts with prostate-derived Ets factor and regulates the activity of the PSA promoter
    • Chen H, Nandi AK, Li X, Bieberich CJ. NKX-3.1 interacts with prostate-derived Ets factor and regulates the activity of the PSA promoter. Cancer Res 2002; 62: 338-40
    • (2002) Cancer Res , vol.62 , pp. 338-340
    • Chen, H.1    Nandi, A.K.2    Li, X.3    Bieberich, C.J.4
  • 15
    • 0036782277 scopus 로고    scopus 로고
    • Deregulated homeobox gene expression in cancer: Cause or consequence?
    • Abate-Shen C. Deregulated homeobox gene expression in cancer: cause or consequence? Nat. Rev. Cancer 2002; 2: 777-85
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 777-785
    • Abate-Shen, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.