Early stage radiation-induced lung injury detected using hyperpolarized 129Xe Morphometry: Proof-of-concept demonstration in a rat model

Magnetic Resonance in Medicine

Volumn 75, Issue 6, 2016, Pages 2421-2431

  Ouriadov, Alexei ^a   Fox, Matthew ^a,b   Hegarty, Elaine ^a   Parraga, Grace ^a,b   Wong, Eugene ^b   Santyr, Giles E ^a,b,c  

^a ROBARTS RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

ADC; anisotropy; hyperpolarized; lung; morphometry; RILI; xenon 129

Indexed keywords

ANISOTROPY; BIOLOGICAL RADIATION EFFECTS; DIFFUSION; RADIOTHERAPY; RATS;

DIFFUSION WEIGHTED IMAGES; DIFFUSION-WEIGHTED MRI; DOSE LIMITING TOXICITY; HYPERPOLARIZED; LUNG; MORPHOLOGICAL CHANGES; MORPHOMETRY; RILI;

BIOLOGICAL ORGANS;

129 XENON; UNCLASSIFIED DRUG; XENON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANISOTROPY; ARTICLE; CANCER RADIOTHERAPY; COHORT ANALYSIS; CONTROLLED STUDY; DIFFUSION WEIGHTED IMAGING; FEMALE; HISTOPATHOLOGY; HYPERPOLARIZATION; IMAGE PROCESSING; LUNG CANCER; LUNG INJURY; LUNG PARENCHYMA; MALE; MORPHOMETRICS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; RADIATION EXPOSURE; RADIATION INDUCED LUNG INJURY; RADIATION PNEUMONIA; RAT; ANIMAL; COMPUTER ASSISTED DIAGNOSIS; CYTOCHEMISTRY; DIAGNOSTIC IMAGING; PATHOLOGY; PROCEDURES; RADIATION INJURY; SPRAGUE DAWLEY RAT;

ANIMALS; DIFFUSION MAGNETIC RESONANCE IMAGING; HISTOCYTOCHEMISTRY; IMAGE INTERPRETATION, COMPUTER-ASSISTED; LUNG INJURY; RADIATION INJURIES; RATS; RATS, SPRAGUE-DAWLEY; XENON ISOTOPES;

EID: 84936805621     PISSN: 07403194     EISSN: 15222594     Source Type: Journal    
DOI: 10.1002/mrm.25825     Document Type: Article

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