Mapping metabolic changes associated with early Radiation Induced Lung Injury post conformal radiotherapy using hyperpolarized 13C-pyruvate Magnetic Resonance Spectroscopic Imaging

Radiotherapy and Oncology

Volumn 110, Issue 2, 2014, Pages 317-322

  Thind, Kundan ^a,b   Jensen, Michael D ^a   Hegarty, Elaine ^b   Chen, Albert P ^c   Lim, Heeseung ^a,b   Martinez Santiesteban, Francisco ^b   Van Dyk, Jake ^a   Wong, Eugene ^a,b   Scholl, Timothy J ^b   Santyr, Giles E ^a,b  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b ROBARTS RESEARCH INSTITUTE   (Canada)

^c GE HEALTHCARE   (Canada)

Author keywords

Conformal radiotherapy; Macrophage; MRI; Radiation Induced Lungs Injury; Radiation Pneumonitis

Indexed keywords

LACTIC ACID; PYRUVIC ACID; CARBON; OXYGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL BLOOD; ARTERIAL OXYGEN TENSION; ARTICLE; BLOOD ANALYSIS; COMPUTER ASSISTED RADIOTHERAPY; CONTROLLED STUDY; HISTOLOGY; LACTATE BLOOD LEVEL; LUNG CANCER; LUNG INJURY; MACROPHAGE; MALE; MICRO-COMPUTED TOMOGRAPHY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; RADIATION PNEUMONIA; RAT; ANIMAL; BLOOD; CARBON NUCLEAR MAGNETIC RESONANCE; HEART; LUNG; METABOLISM; PATHOLOGY; PROCEDURES; RADIATION INJURIES, EXPERIMENTAL; RADIATION PNEUMONITIS; RADIATION RESPONSE; SPRAGUE DAWLEY RAT;

ANIMALS; CARBON ISOTOPES; CARBON-13 MAGNETIC RESONANCE SPECTROSCOPY; HEART; LACTIC ACID; LUNG; LUNG INJURY; MALE; OXYGEN; PYRUVIC ACID; RADIATION INJURIES, EXPERIMENTAL; RADIATION PNEUMONITIS; RADIOTHERAPY, CONFORMAL; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84896389769     PISSN: 01678140     EISSN: 18790887     Source Type: Journal    
DOI: 10.1016/j.radonc.2013.11.016     Document Type: Article

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