Imaging lung microstructure in mice with hyperpolarized 3He diffusion MRI

Magnetic Resonance in Medicine

Volumn 65, Issue 3, 2011, Pages 620-626

  Wang, Wei ^a   Nguyen, Nguyet M ^a   Yablonskiy, Dmitriy A ^a   Sukstanskii, Alexander L ^a   Osmanagic, Emir ^a,b   Atkinson, Jeffrey J ^a   Conradi, Mark S ^a   Woods, Jason C ^a  

^a WASHINGTON UNIVERSITY   (United States)

^b WASHINGTON UNIVERSITY IN ST LOUIS   (United States)

Author keywords

alveolar size; diffusion; lung morphometry; mouse

Indexed keywords

DIFFUSION; MAGNETIC RESONANCE IMAGING; MAMMALS; MICROSTRUCTURE;

ALVEOLAR SIZE; DIFFUSION MRIS; HYPERPOLARIZED; LUNG MICROSTRUCTURES; MORPHOMETRY; MOUSE; QUANTITATIVE INFORMATION; QUANTITATIVE MEASUREMENT;

BIOLOGICAL ORGANS;

HELIUM; HELIUM 3; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; DIFFUSION WEIGHTED IMAGING; FEMALE; LUNG ALVEOLUS; LUNG DISEASE; LUNG STRUCTURE; MOUSE; NONHUMAN; QUANTITATIVE ANALYSIS;

EID: 79951823588     PISSN: 07403194     EISSN: 15222594     Source Type: Journal    
DOI: 10.1002/mrm.22737     Document Type: Article

References (31)

1. Ochs M,. A brief update on lung stereology. J Microsc 2006; 222 (Pt 3): 188-200. (Pubitemid 44035814)
2. Weibel ER,. What makes a good lung? Swiss Med Wkly 2009; 139: 375-386.
3. Knudsen L, Weibel ER, Gundersen HJ, Weinstein FV, Ochs M,. Assessment of air space size characteristics by intercept (chord) measurement: an accurate and efficient stereological approach. J Appl Physiol 2009; 108: 412-421.
4. Hsia CCW, Hyde DM, Ochs M, Weibel ER,. An official research policy statement of the american thoracic society/european respiratory society: standards for quantitative assessment of lung structure. Am J Respir Crit Care Med 2010; 181: 394-418.
5. Chen XJ, Hedlund LW, Moller HE, Chawla MS, Maronpot RR, Johnson GA,. Detection of emphysema in rat lungs by using magnetic resonance measurements of 3He diffusion. Proc Natl Acad Sci USA 2000; 97: 11478-11481.
6. Saam BT, Yablonskiy DA, Kodibagkar VD, Leawoods JC, Gierada DS, Cooper JD, Lefrak SS, Conradi MS,. MR imaging of diffusion of (3)He gas in healthy and diseased lungs. Magn Reson Med 2000; 44: 174-179. (Pubitemid 30616020)
7. Salerno M, de Lange EE, Altes TA, Truwit JD, Brookeman JR, Mugler JP III,. Emphysema: hyperpolarized helium 3 diffusion MR imaging of the lungs compared with spirometric indexes-initial experience. Radiology 2002; 222: 252-260. (Pubitemid 34031496)
8. Yablonskiy DA, Sukstanskii AL, Leawoods JC, Gierada DS, Bretthorst GL, Lefrak SS, Cooper JD, Conradi MS,. Quantitative in vivo assessment of lung microstructure at the alveolar level with hyperpolarized 3He diffusion MRI. Proc Natl Acad Sci USA 2002; 99: 3111-3116. (Pubitemid 34240594)
9. Peces-Barba G, Ruiz-Cabello J, Cremillieux Y, Rodriguez I, Dupuich D, Callot V, Ortega M, Rubio Arbo ML, Cortijo M, Gonzalez-Mangado N,. Helium-3 MRI diffusion coefficient: correlation to morphometry in a model of mild emphysema. Eur Respir J 2003; 22: 14-19. (Pubitemid 36896465)
10. 3He diffusion MRI and histology in pulmonary emphysema. Magn Reson Med 2006; 56: 1293-1300. (Pubitemid 44865311)
11. 3He MRI in mouse models of asthma. Magn Reson Med 2007; 58: 893-900. (Pubitemid 350074356)
12. 3He diffusion MRI: theoretical background. J Magn Reson 2008; 190: 200-210.
13. 3He diffusion MRI. J Appl Physiol 2009; 107: 1258-1265.
14. 3He lung morphometry technique. J Appl Physiol 2010 Aug 26 [Epub ahead of print; PMID 20798272].
15. Rodriguez M, Bur S, Favre A, Weibel ER,. Pulmonary acinus: geometry and morphometry of the peripheral airway system in rat and rabbit. Am J Anat 1987; 180: 143-155. (Pubitemid 17148456)
16. Haefeli-Bleuer B, Weibel ER,. Morphometry of the human pulmonary acinus. Anat Rec 1988; 220: 401-414.
17. Quirk JD, Sukstanskii AL, Bretthorst GL, Yablonskiy DA,. Optimal decay rate constant estimates from phased array data utilizing joint Bayesian analysis. J Magn Reson 2009; 198: 49-56.
18. Bretthorst GL,. An introduction to parameter estimation using Bayesian probability theory. In:, Fougèere PF, editor. An introduction to parameter estimation using Bayesian probability theory. Dartmouth: Kluwer Academic Publishers; 1989. pp 53-79.
19. Weibel ER,. Stereological methods, Vol. 2: theoretical foundations. London: Academic Press; 1980.
20. 3He MRI of mouse lung. Magn Reson Med 2004; 52: 1310-1317. (Pubitemid 39612819)
21. Walker T, Happer W,. Spin-exchange optical pumping of noble-gas nuclei. Rev Mod Phys 1997; 69: 629-642.
22. Atkinson JJ, Holmbeck K, Yamada S, Birkedal-Hansen H, Parks WC, Senior RM,. Membrane-type 1 matrix metalloproteinase is required for normal alveolar development. Dev Dyn 2005; 232: 1079-1090. (Pubitemid 40463961)
23. Hirschfelder JO,. Molecular theory of gases and liquids. New York: Wiley; 1954.
24. Soutiere SE, Mitzner W,. On defining total lung capacity in the mouse. J Appl Physiol 2004; 96: 1658-1664. (Pubitemid 38579988)
25. Parameswaran H, Bartolak-Suki E, Hamakawa H, Majumdar A, Allen P, Suki B,. Three-dimensional measurement of alveolar airspace volumes in normal and emphysematous lungs using micro-CT. J Appl Physiol 2009; 107: 583-592.
26. Fehrenbach H, Voswinckel R, Michl V, Mehling T, Fehrenbach A, Seeger W, Nyengaard JR,. Neoalveolarisation contributes to compensatory lung growth following pneumonectomy in mice. Eur Respir J 2008; 31: 515-522.
27. Voswinckel R, Motejl V, Fehrenbach A, Wegmann M, Mehling T, Fehrenbach H, Seeger W,. Characterisation of post-pneumonectomy lung growth in adult mice. Eur Respir J 2004; 24: 524-532. (Pubitemid 39406123)
28. Mauad T, Rivero DH, de Oliveira RC, Lichtenfels AJ, Guimaraes ET, de Andre PA, Kasahara DI, Bueno HM, Saldiva PH,. Chronic exposure to ambient levels of urban particles affects mouse lung development. Am J Respir Crit Care Med 2008; 178: 721-728.
29. Knust J, Ochs M, Gundersen HJ, Nyengaard JR,. Stereological estimates of alveolar number and size and capillary length and surface area in mice lungs. Anat Rec (Hoboken) 2009; 292: 113-122.
30. Knudsen L, Ochs M, Mackay R, Townsend P, Deb R, Muhlfeld C, Richter J, Gilbert F, Hawgood S, Reid K, Clark H,. Truncated recombinant human SP-D attenuates emphysema and type II cell changes in SP-D deficient mice. Respir Res 2007; 8: 70.
31. Mitzner W, Fallica J, Bishai J,. Anisotropic nature of mouse lung parenchyma. Ann Biomed Eng 2008; 36: 2111-2120.