메뉴 건너뛰기




Volumn 8, Issue 1, 2015, Pages

Exosomes in cancer: Small particle, big player

Author keywords

Biomarker; Cancer; Exosomes; Intercellular communication; Target

Indexed keywords

MICRORNA; SURVIVIN; THROMBOPLASTIN; TUMOR MARKER;

EID: 84936756990     PISSN: None     EISSN: 17568722     Source Type: Journal    
DOI: 10.1186/s13045-015-0181-x     Document Type: Review
Times cited : (652)

References (135)
  • 1
    • 0036676445 scopus 로고    scopus 로고
    • Exosomes: Composition, biogenesis and function
    • 1:CAS:528:DC%2BD38XlslGru7k%3D 12154376
    • Thery C, Zitvogel L, Amigorena S. Exosomes: composition, biogenesis and function. Nat Rev Immunol. 2002;2(8):569-79.
    • (2002) Nat Rev Immunol , vol.2 , Issue.8 , pp. 569-579
    • Thery, C.1    Zitvogel, L.2    Amigorena, S.3
  • 2
    • 40049112564 scopus 로고    scopus 로고
    • Ceramide triggers budding of exosome vesicles into multivesicular endosomes
    • 1:CAS:528:DC%2BD1cXisVSksLY%3D 18309083
    • Trajkovic K, Hsu C, Chiantia S, Rajendran L, Wenzel D, Wieland F, et al. Ceramide triggers budding of exosome vesicles into multivesicular endosomes. Science. 2008;319(5867):1244-7.
    • (2008) Science , vol.319 , Issue.5867 , pp. 1244-1247
    • Trajkovic, K.1    Hsu, C.2    Chiantia, S.3    Rajendran, L.4    Wenzel, D.5    Wieland, F.6
  • 3
  • 5
    • 77951183654 scopus 로고    scopus 로고
    • Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A-C
    • 1:CAS:528:DC%2BC3cXlt1Kgsr4%3D 2856897 20404108
    • Hsu C, Morohashi Y, Yoshimura S, Manrique-Hoyos N, Jung S, Lauterbach MA, et al. Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A-C. J Cell Biol. 2010;189(2):223-32.
    • (2010) J Cell Biol , vol.189 , Issue.2 , pp. 223-232
    • Hsu, C.1    Morohashi, Y.2    Yoshimura, S.3    Manrique-Hoyos, N.4    Jung, S.5    Lauterbach, M.A.6
  • 6
    • 0037490207 scopus 로고    scopus 로고
    • Exosome release is regulated by a calcium-dependent mechanism in K562 cells
    • 1:CAS:528:DC%2BD3sXktVaqurk%3D 12639953
    • Savina A, Furlan M, Vidal M, Colombo MI. Exosome release is regulated by a calcium-dependent mechanism in K562 cells. J Biol Chem. 2003;278(22):20083-90.
    • (2003) J Biol Chem , vol.278 , Issue.22 , pp. 20083-20090
    • Savina, A.1    Furlan, M.2    Vidal, M.3    Colombo, M.I.4
  • 7
    • 71749102668 scopus 로고    scopus 로고
    • Microenvironmental pH is a key factor for exosome traffic in tumor cells
    • 1:CAS:528:DC%2BD1MXhsVymu7fN 2797191 19801663
    • Parolini I, Federici C, Raggi C, Lugini L, Palleschi S, De Milito A, et al. Microenvironmental pH is a key factor for exosome traffic in tumor cells. J Biol Chem. 2009;284(49):34211-22.
    • (2009) J Biol Chem , vol.284 , Issue.49 , pp. 34211-34222
    • Parolini, I.1    Federici, C.2    Raggi, C.3    Lugini, L.4    Palleschi, S.5    De Milito, A.6
  • 8
    • 13544256266 scopus 로고    scopus 로고
    • Oncogenic events regulate tissue factor expression in colorectal cancer cells: Implications for tumor progression and angiogenesis
    • 1:CAS:528:DC%2BD2MXhsVCqu74%3D 15494427
    • Yu JL, May L, Lhotak V, Shahrzad S, Shirasawa S, Weitz JI, et al. Oncogenic events regulate tissue factor expression in colorectal cancer cells: implications for tumor progression and angiogenesis. Blood. 2005;105(4):1734-41.
    • (2005) Blood , vol.105 , Issue.4 , pp. 1734-1741
    • Yu, J.L.1    May, L.2    Lhotak, V.3    Shahrzad, S.4    Shirasawa, S.5    Weitz, J.I.6
  • 9
    • 33646416463 scopus 로고    scopus 로고
    • The regulation of exosome secretion: A novel function of the p53 protein
    • 1:CAS:528:DC%2BD28XjvF2kt74%3D 16651434
    • Yu X, Harris SL, Levine AJ. The regulation of exosome secretion: a novel function of the p53 protein. Cancer Res. 2006;66(9):4795-801.
    • (2006) Cancer Res , vol.66 , Issue.9 , pp. 4795-4801
    • Yu, X.1    Harris, S.L.2    Levine, A.J.3
  • 10
    • 54049088501 scopus 로고    scopus 로고
    • Exosome secretion, including the DNA damage-induced p53-dependent secretory pathway, is severely compromised in TSAP6/Steap3-null mice
    • 1:CAS:528:DC%2BD1cXht1aru7zK 18617898
    • Lespagnol A, Duflaut D, Beekman C, Blanc L, Fiucci G, Marine JC, et al. Exosome secretion, including the DNA damage-induced p53-dependent secretory pathway, is severely compromised in TSAP6/Steap3-null mice. Cell Death Differ. 2008;15(11):1723-33.
    • (2008) Cell Death Differ , vol.15 , Issue.11 , pp. 1723-1733
    • Lespagnol, A.1    Duflaut, D.2    Beekman, C.3    Blanc, L.4    Fiucci, G.5    Marine, J.C.6
  • 11
    • 84875994843 scopus 로고    scopus 로고
    • Heparanase regulates secretion, composition, and function of tumor cell-derived exosomes
    • 1:CAS:528:DC%2BC3sXlsVCqsbc%3D 3617250 23430739
    • Thompson CA, Purushothaman A, Ramani VC, Vlodavsky I, Sanderson RD. Heparanase regulates secretion, composition, and function of tumor cell-derived exosomes. J Biol Chem. 2013;288(14):10093-9.
    • (2013) J Biol Chem , vol.288 , Issue.14 , pp. 10093-10099
    • Thompson, C.A.1    Purushothaman, A.2    Ramani, V.C.3    Vlodavsky, I.4    Sanderson, R.D.5
  • 12
    • 84896700681 scopus 로고    scopus 로고
    • Regulation of exosome release from mammary epithelial and breast cancer cells - A new regulatory pathway
    • 1:CAS:528:DC%2BC2cXhtlKis7Y%3D 24462375
    • Riches A, Campbell E, Borger E, Powis S. Regulation of exosome release from mammary epithelial and breast cancer cells - a new regulatory pathway. Eur J Cancer. 2014;50(5):1025-34.
    • (2014) Eur J Cancer , vol.50 , Issue.5 , pp. 1025-1034
    • Riches, A.1    Campbell, E.2    Borger, E.3    Powis, S.4
  • 13
    • 36248944555 scopus 로고    scopus 로고
    • Identification of Tim4 as a phosphatidylserine receptor
    • 1:CAS:528:DC%2BD2sXhtlajs77P 17960135
    • Miyanishi M, Tada K, Koike M, Uchiyama Y, Kitamura T, Nagata S. Identification of Tim4 as a phosphatidylserine receptor. Nature. 2007;450(7168):435-9.
    • (2007) Nature , vol.450 , Issue.7168 , pp. 435-439
    • Miyanishi, M.1    Tada, K.2    Koike, M.3    Uchiyama, Y.4    Kitamura, T.5    Nagata, S.6
  • 14
    • 22044447897 scopus 로고    scopus 로고
    • ICAM-1 on exosomes from mature dendritic cells is critical for efficient naive T-cell priming
    • 1:CAS:528:DC%2BD2MXlvVWjsbs%3D 15790784
    • Segura E, Nicco C, Lombard B, Veron P, Raposo G, Batteux F, et al. ICAM-1 on exosomes from mature dendritic cells is critical for efficient naive T-cell priming. Blood. 2005;106(1):216-23.
    • (2005) Blood , vol.106 , Issue.1 , pp. 216-223
    • Segura, E.1    Nicco, C.2    Lombard, B.3    Veron, P.4    Raposo, G.5    Batteux, F.6
  • 15
    • 77957269172 scopus 로고    scopus 로고
    • Visualizing of the cellular uptake and intracellular trafficking of exosomes by live-cell microscopy
    • 1:CAS:528:DC%2BC3cXhtlSnt7jE 20533300
    • Tian T, Wang Y, Wang H, Zhu Z, Xiao Z. Visualizing of the cellular uptake and intracellular trafficking of exosomes by live-cell microscopy. J Cell Biochem. 2010;111(2):488-96.
    • (2010) J Cell Biochem , vol.111 , Issue.2 , pp. 488-496
    • Tian, T.1    Wang, Y.2    Wang, H.3    Zhu, Z.4    Xiao, Z.5
  • 16
    • 77953154769 scopus 로고    scopus 로고
    • Cellular internalization of exosomes occurs through phagocytosis
    • 1:CAS:528:DC%2BC3cXlt1Kis7Y%3D 20136776
    • Feng D, Zhao WL, Ye YY, Bai XC, Liu RQ, Chang LF, et al. Cellular internalization of exosomes occurs through phagocytosis. Traffic. 2010;11(5):675-87.
    • (2010) Traffic , vol.11 , Issue.5 , pp. 675-687
    • Feng, D.1    Zhao, W.L.2    Ye, Y.Y.3    Bai, X.C.4    Liu, R.Q.5    Chang, L.F.6
  • 17
    • 79953081976 scopus 로고    scopus 로고
    • Interaction and uptake of exosomes by ovarian cancer cells
    • 1:CAS:528:DC%2BC3MXksFCgsLs%3D 3072949 21439085
    • Escrevente C, Keller S, Altevogt P, Costa J. Interaction and uptake of exosomes by ovarian cancer cells. BMC Cancer. 2011;11:108.
    • (2011) BMC Cancer , vol.11 , pp. 108
    • Escrevente, C.1    Keller, S.2    Altevogt, P.3    Costa, J.4
  • 18
    • 84886387008 scopus 로고    scopus 로고
    • Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity
    • 1:CAS:528:DC%2BC3sXhslejsLjJ 3808637 24101524
    • Christianson HC, Svensson KJ, van Kuppevelt TH, Li JP, Belting M. Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity. Proc Natl Acad Sci U S A. 2013;110(43):17380-5.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , Issue.43 , pp. 17380-17385
    • Christianson, H.C.1    Svensson, K.J.2    Van Kuppevelt, T.H.3    Li, J.P.4    Belting, M.5
  • 19
    • 84901842265 scopus 로고    scopus 로고
    • Double-stranded DNA in exosomes: A novel biomarker in cancer detection
    • 1:CAS:528:DC%2BC2cXmtVCqtb8%3D 4042169 24710597
    • Thakur BK, Zhang H, Becker A, Matei I, Huang Y, Costa-Silva B, et al. Double-stranded DNA in exosomes: a novel biomarker in cancer detection. Cell Res. 2014;24(6):766-9.
    • (2014) Cell Res , vol.24 , Issue.6 , pp. 766-769
    • Thakur, B.K.1    Zhang, H.2    Becker, A.3    Matei, I.4    Huang, Y.5    Costa-Silva, B.6
  • 20
    • 34249302620 scopus 로고    scopus 로고
    • Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
    • 1:CAS:528:DC%2BD2sXmtVSmtb8%3D 17486113
    • Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol. 2007;9(6):654-9.
    • (2007) Nat Cell Biol , vol.9 , Issue.6 , pp. 654-659
    • Valadi, H.1    Ekstrom, K.2    Bossios, A.3    Sjostrand, M.4    Lee, J.J.5    Lotvall, J.O.6
  • 21
    • 85016448020 scopus 로고    scopus 로고
    • Minimal experimental requirements for definition of extracellular vesicles and their functions: A position statement from the International Society for Extracellular Vesicles
    • 25536934
    • Lotvall J, Hill AF, Hochberg F, Buzas EI, Di Vizio D, Gardiner C, et al. Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular Vesicles. J Extracell Vesicles. 2014;3:26913.
    • (2014) J Extracell Vesicles , vol.3 , pp. 26913
    • Lotvall, J.1    Hill, A.F.2    Hochberg, F.3    Buzas, E.I.4    Di Vizio, D.5    Gardiner, C.6
  • 22
    • 84896323201 scopus 로고    scopus 로고
    • Neoplastic reprogramming of patient-derived adipose stem cells by prostate cancer cell-associated exosomes
    • 1:CAS:528:DC%2BC2cXoslOktL8%3D 4184251 24715691
    • Abd Elmageed ZY, Yang Y, Thomas R, Ranjan M, Mondal D, Moroz K, et al. Neoplastic reprogramming of patient-derived adipose stem cells by prostate cancer cell-associated exosomes. Stem Cells. 2014;32(4):983-97.
    • (2014) Stem Cells , vol.32 , Issue.4 , pp. 983-997
    • Abd Elmageed, Z.Y.1    Yang, Y.2    Thomas, R.3    Ranjan, M.4    Mondal, D.5    Moroz, K.6
  • 23
    • 84911966357 scopus 로고    scopus 로고
    • Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis
    • 1:CAS:528:DC%2BC2cXhvVantbbM 25446899
    • Melo SA, Sugimoto H, O'Connell JT, Kato N, Villanueva A, Vidal A, et al. Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis. Cancer Cell. 2014;26(5):707-21.
    • (2014) Cancer Cell , vol.26 , Issue.5 , pp. 707-721
    • Melo, S.A.1    Sugimoto, H.2    O'Connell, J.T.3    Kato, N.4    Villanueva, A.5    Vidal, A.6
  • 24
    • 84902080204 scopus 로고    scopus 로고
    • Populational equilibrium through exosome-mediated Wnt signaling in tumor progression of diffuse large B-cell lymphoma
    • 1:CAS:528:DC%2BC2cXmtVOjurk%3D 24563408
    • Koch R, Demant M, Aung T, Diering N, Cicholas A, Chapuy B, et al. Populational equilibrium through exosome-mediated Wnt signaling in tumor progression of diffuse large B-cell lymphoma. Blood. 2014;123(14):2189-98.
    • (2014) Blood , vol.123 , Issue.14 , pp. 2189-2198
    • Koch, R.1    Demant, M.2    Aung, T.3    Diering, N.4    Cicholas, A.5    Chapuy, B.6
  • 25
    • 63949085987 scopus 로고    scopus 로고
    • Extracellular, cell-permeable survivin inhibits apoptosis while promoting proliferative and metastatic potential
    • 1:CAS:528:DC%2BD1MXktVGksbY%3D 2669990 19293795
    • Khan S, Aspe JR, Asumen MG, Almaguel F, Odumosu O, Acevedo-Martinez S, et al. Extracellular, cell-permeable survivin inhibits apoptosis while promoting proliferative and metastatic potential. Br J Cancer. 2009;100(7):1073-86.
    • (2009) Br J Cancer , vol.100 , Issue.7 , pp. 1073-1086
    • Khan, S.1    Aspe, J.R.2    Asumen, M.G.3    Almaguel, F.4    Odumosu, O.5    Acevedo-Martinez, S.6
  • 26
    • 43049139913 scopus 로고    scopus 로고
    • Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells
    • 1:CAS:528:DC%2BD1cXltl2isLw%3D 18425114
    • Al-Nedawi K, Meehan B, Micallef J, Lhotak V, May L, Guha A, et al. Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells. Nat Cell Biol. 2008;10(5):619-24.
    • (2008) Nat Cell Biol , vol.10 , Issue.5 , pp. 619-624
    • Al-Nedawi, K.1    Meehan, B.2    Micallef, J.3    Lhotak, V.4    May, L.5    Guha, A.6
  • 27
    • 84893188871 scopus 로고    scopus 로고
    • Tumor-derived exosomes are enriched in DeltaNp73, which promotes oncogenic potential in acceptor cells and correlates with patient survival
    • 1:CAS:528:DC%2BC3sXhvFOnt7rM 24067531
    • Soldevilla B, Rodriguez M, San Millan C, Garcia V, Fernandez-Perianez R, Gil-Calderon B, et al. Tumor-derived exosomes are enriched in DeltaNp73, which promotes oncogenic potential in acceptor cells and correlates with patient survival. Hum Mol Genet. 2014;23(2):467-78.
    • (2014) Hum Mol Genet , vol.23 , Issue.2 , pp. 467-478
    • Soldevilla, B.1    Rodriguez, M.2    San Millan, C.3    Garcia, V.4    Fernandez-Perianez, R.5    Gil-Calderon, B.6
  • 28
    • 84900505110 scopus 로고    scopus 로고
    • Exosome-mediated crosstalk between chronic myelogenous leukemia cells and human bone marrow stromal cells triggers an interleukin 8-dependent survival of leukemia cells
    • 1:CAS:528:DC%2BC2cXlt1Chu70%3D 24657661
    • Corrado C, Raimondo S, Saieva L, Flugy AM, De Leo G, Alessandro R. Exosome-mediated crosstalk between chronic myelogenous leukemia cells and human bone marrow stromal cells triggers an interleukin 8-dependent survival of leukemia cells. Cancer Lett. 2014;348(1-2):71-6.
    • (2014) Cancer Lett , vol.348 , Issue.1-2 , pp. 71-76
    • Corrado, C.1    Raimondo, S.2    Saieva, L.3    Flugy, A.M.4    De Leo, G.5    Alessandro, R.6
  • 29
    • 84875846330 scopus 로고    scopus 로고
    • BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression
    • 1:CAS:528:DC%2BC3sXlvVKhsLo%3D 3613927 23454749
    • Roccaro AM, Sacco A, Maiso P, Azab AK, Tai YT, Reagan M, et al. BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression. J Clin Invest. 2013;123(4):1542-55.
    • (2013) J Clin Invest , vol.123 , Issue.4 , pp. 1542-1555
    • Roccaro, A.M.1    Sacco, A.2    Maiso, P.3    Azab, A.K.4    Tai, Y.T.5    Reagan, M.6
  • 30
    • 77953142134 scopus 로고    scopus 로고
    • Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes
    • 1:CAS:528:DC%2BC3cXpsFCrt7g%3D 2877972 20124223
    • Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, et al. Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes. Mol Cell Proteomics. 2010;9(6):1085-99.
    • (2010) Mol Cell Proteomics , vol.9 , Issue.6 , pp. 1085-1099
    • Park, J.E.1    Tan, H.S.2    Datta, A.3    Lai, R.C.4    Zhang, H.5    Meng, W.6
  • 31
    • 76749106591 scopus 로고    scopus 로고
    • Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation
    • 1:CAS:528:DC%2BC3cXhvFaktrs%3D 20124479
    • Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, et al. Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation. Cancer Res. 2010;70(4):1668-78.
    • (2010) Cancer Res , vol.70 , Issue.4 , pp. 1668-1678
    • Nazarenko, I.1    Rana, S.2    Baumann, A.3    McAlear, J.4    Hellwig, A.5    Trendelenburg, M.6
  • 32
    • 84876927914 scopus 로고    scopus 로고
    • Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development
    • 1:CAS:528:DC%2BC3sXos1Oitrc%3D 3645587 23589885
    • Kucharzewska P, Christianson HC, Welch JE, Svensson KJ, Fredlund E, Ringner M, et al. Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development. Proc Natl Acad Sci U S A. 2013;110(18):7312-7.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , Issue.18 , pp. 7312-7317
    • Kucharzewska, P.1    Christianson, H.C.2    Welch, J.E.3    Svensson, K.J.4    Fredlund, E.5    Ringner, M.6
  • 33
    • 84898476721 scopus 로고    scopus 로고
    • Cancer-secreted miR-105 destroys vascular endothelial barriers to promote metastasis
    • 1:CAS:528:DC%2BC2cXmt1ahtbc%3D 4016197 24735924
    • Zhou W, Fong MY, Min Y, Somlo G, Liu L, Palomares MR, et al. Cancer-secreted miR-105 destroys vascular endothelial barriers to promote metastasis. Cancer Cell. 2014;25(4):501-15.
    • (2014) Cancer Cell , vol.25 , Issue.4 , pp. 501-515
    • Zhou, W.1    Fong, M.Y.2    Min, Y.3    Somlo, G.4    Liu, L.5    Palomares, M.R.6
  • 34
    • 84879419464 scopus 로고    scopus 로고
    • Leukemia cell to endothelial cell communication via exosomal miRNAs
    • 1:CAS:528:DC%2BC38XhtVehsb%2FN 22797057
    • Umezu T, Ohyashiki K, Kuroda M, Ohyashiki JH. Leukemia cell to endothelial cell communication via exosomal miRNAs. Oncogene. 2013;32(22):2747-55.
    • (2013) Oncogene , vol.32 , Issue.22 , pp. 2747-2755
    • Umezu, T.1    Ohyashiki, K.2    Kuroda, M.3    Ohyashiki, J.H.4
  • 35
    • 84888986034 scopus 로고    scopus 로고
    • Exosomes derived from hypoxic leukemia cells enhance tube formation in endothelial cells
    • 1:CAS:528:DC%2BC3sXhvVKnsL3K 3843049 24133215
    • Tadokoro H, Umezu T, Ohyashiki K, Hirano T, Ohyashiki JH. Exosomes derived from hypoxic leukemia cells enhance tube formation in endothelial cells. J Biol Chem. 2013;288(48):34343-51.
    • (2013) J Biol Chem , vol.288 , Issue.48 , pp. 34343-34351
    • Tadokoro, H.1    Umezu, T.2    Ohyashiki, K.3    Hirano, T.4    Ohyashiki, J.H.5
  • 36
    • 84919680938 scopus 로고    scopus 로고
    • Exosomal miR-135b shed from hypoxic multiple myeloma cells enhances angiogenesis by targeting factor-inhibiting HIF-1
    • 1:CAS:528:DC%2BC2MXlvFCi 4263983 25320245
    • Umezu T, Tadokoro H, Azuma K, Yoshizawa S, Ohyashiki K, Ohyashiki JH. Exosomal miR-135b shed from hypoxic multiple myeloma cells enhances angiogenesis by targeting factor-inhibiting HIF-1. Blood. 2014;124(25):3748-57.
    • (2014) Blood , vol.124 , Issue.25 , pp. 3748-3757
    • Umezu, T.1    Tadokoro, H.2    Azuma, K.3    Yoshizawa, S.4    Ohyashiki, K.5    Ohyashiki, J.H.6
  • 37
    • 84896408214 scopus 로고    scopus 로고
    • Exosomal HIF1alpha supports invasive potential of nasopharyngeal carcinoma-associated LMP1-positive exosomes
    • 1:CAS:528:DC%2BC2cXks12lu7g%3D 4162459 24662828
    • Aga M, Bentz GL, Raffa S, Torrisi MR, Kondo S, Wakisaka N, et al. Exosomal HIF1alpha supports invasive potential of nasopharyngeal carcinoma-associated LMP1-positive exosomes. Oncogene. 2014;33(37):4613-22.
    • (2014) Oncogene , vol.33 , Issue.37 , pp. 4613-4622
    • Aga, M.1    Bentz, G.L.2    Raffa, S.3    Torrisi, M.R.4    Kondo, S.5    Wakisaka, N.6
  • 38
    • 84908139770 scopus 로고    scopus 로고
    • Cellular disposal of miR23b by RAB27-dependent exosome release is linked to acquisition of metastatic properties
    • 1:CAS:528:DC%2BC2cXhslCqu7fN 25261234
    • Ostenfeld MS, Jeppesen DK, Laurberg JR, Boysen AT, Bramsen JB, Primdal-Bengtson B, et al. Cellular disposal of miR23b by RAB27-dependent exosome release is linked to acquisition of metastatic properties. Cancer Res. 2014;74(20):5758-71.
    • (2014) Cancer Res , vol.74 , Issue.20 , pp. 5758-5771
    • Ostenfeld, M.S.1    Jeppesen, D.K.2    Laurberg, J.R.3    Boysen, A.T.4    Bramsen, J.B.5    Primdal-Bengtson, B.6
  • 39
    • 84862007577 scopus 로고    scopus 로고
    • Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET
    • 1:CAS:528:DC%2BC38XnsFKgtLw%3D 3645291 22635005
    • Peinado H, Aleckovic M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, et al. Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Nat Med. 2012;18(6):883-91.
    • (2012) Nat Med , vol.18 , Issue.6 , pp. 883-891
    • Peinado, H.1    Aleckovic, M.2    Lavotshkin, S.3    Matei, I.4    Costa-Silva, B.5    Moreno-Bueno, G.6
  • 40
    • 84892607130 scopus 로고    scopus 로고
    • Oncogenic KIT-containing exosomes increase gastrointestinal stromal tumor cell invasion
    • 1:CAS:528:DC%2BC2cXotFOisg%3D%3D 3896203 24379393
    • Atay S, Banskota S, Crow J, Sethi G, Rink L, Godwin AK. Oncogenic KIT-containing exosomes increase gastrointestinal stromal tumor cell invasion. Proc Natl Acad Sci U S A. 2014;111(2):711-6.
    • (2014) Proc Natl Acad Sci U S A , vol.111 , Issue.2 , pp. 711-716
    • Atay, S.1    Banskota, S.2    Crow, J.3    Sethi, G.4    Rink, L.5    Godwin, A.K.6
  • 41
    • 84874959843 scopus 로고    scopus 로고
    • Imaging exosome transfer from breast cancer cells to stroma at metastatic sites in orthotopic nude-mouse models
    • 1:CAS:528:DC%2BC38XhsFClu7fF 22921594
    • Suetsugu A, Honma K, Saji S, Moriwaki H, Ochiya T, Hoffman RM. Imaging exosome transfer from breast cancer cells to stroma at metastatic sites in orthotopic nude-mouse models. Adv Drug Deliv Rev. 2013;65(3):383-90.
    • (2013) Adv Drug Deliv Rev , vol.65 , Issue.3 , pp. 383-390
    • Suetsugu, A.1    Honma, K.2    Saji, S.3    Moriwaki, H.4    Ochiya, T.5    Hoffman, R.M.6
  • 42
    • 84871563123 scopus 로고    scopus 로고
    • Exosomes mediate stromal mobilization of autocrine Wnt-PCP signaling in breast cancer cell migration
    • 1:CAS:528:DC%2BC38XhvVymu7nP 23260141
    • Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, et al. Exosomes mediate stromal mobilization of autocrine Wnt-PCP signaling in breast cancer cell migration. Cell. 2012;151(7):1542-56.
    • (2012) Cell , vol.151 , Issue.7 , pp. 1542-1556
    • Luga, V.1    Zhang, L.2    Viloria-Petit, A.M.3    Ogunjimi, A.A.4    Inanlou, M.R.5    Chiu, E.6
  • 43
    • 84862620981 scopus 로고    scopus 로고
    • Activated T cell exosomes promote tumor invasion via Fas signaling pathway
    • 1:CAS:528:DC%2BC38XotFGrurk%3D 22573809
    • Cai Z, Yang F, Yu L, Yu Z, Jiang L, Wang Q, et al. Activated T cell exosomes promote tumor invasion via Fas signaling pathway. J Immunol. 2012;188(12):5954-61.
    • (2012) J Immunol , vol.188 , Issue.12 , pp. 5954-5961
    • Cai, Z.1    Yang, F.2    Yu, L.3    Yu, Z.4    Jiang, L.5    Wang, Q.6
  • 44
    • 80053175966 scopus 로고    scopus 로고
    • Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells
    • 1:CAS:528:DC%2BC3MXhtleis7vM 3190352 21939504
    • Yang M, Chen J, Su F, Yu B, Lin L, Liu Y, et al. Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells. Mol Cancer. 2011;10:117.
    • (2011) Mol Cancer , vol.10 , pp. 117
    • Yang, M.1    Chen, J.2    Su, F.3    Yu, B.4    Lin, L.5    Liu, Y.6
  • 45
    • 84895779700 scopus 로고    scopus 로고
    • Deregulated microRNAs in gastric cancer tissue-derived mesenchymal stem cells: Novel biomarkers and a mechanism for gastric cancer
    • 1:CAS:528:DC%2BC2cXhsVCms7g%3D 3950864 24473397
    • Wang M, Zhao C, Shi H, Zhang B, Zhang L, Zhang X, et al. Deregulated microRNAs in gastric cancer tissue-derived mesenchymal stem cells: novel biomarkers and a mechanism for gastric cancer. Br J Cancer. 2014;110(5):1199-210.
    • (2014) Br J Cancer , vol.110 , Issue.5 , pp. 1199-1210
    • Wang, M.1    Zhao, C.2    Shi, H.3    Zhang, B.4    Zhang, L.5    Zhang, X.6
  • 46
    • 84864503916 scopus 로고    scopus 로고
    • MicroRNAs bind to toll-like receptors to induce prometastatic inflammatory response
    • 1:CAS:528:DC%2BC38Xhtleks7nE 3412003 22753494
    • Fabbri M, Paone A, Calore F, Galli R, Gaudio E, Santhanam R, et al. MicroRNAs bind to toll-like receptors to induce prometastatic inflammatory response. Proc Natl Acad Sci U S A. 2012;109(31):E2110-2116.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , Issue.31 , pp. 2110-2116
    • Fabbri, M.1    Paone, A.2    Calore, F.3    Galli, R.4    Gaudio, E.5    Santhanam, R.6
  • 47
    • 84930170395 scopus 로고    scopus 로고
    • Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver
    • 25985394
    • Costa-Silva B, Aiello NM, Ocean AJ, Singh S, Zhang H, Thakur BK, et al. Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver. Nat Cell Biol. 2015;17(6):816-26.
    • (2015) Nat Cell Biol , vol.17 , Issue.6 , pp. 816-826
    • Costa-Silva, B.1    Aiello, N.M.2    Ocean, A.J.3    Singh, S.4    Zhang, H.5    Thakur, B.K.6
  • 48
    • 84930225521 scopus 로고    scopus 로고
    • In Vivo imaging reveals extracellular vesicle-mediated phenocopying of metastatic behavior
    • 1:CAS:528:DC%2BC2MXpt1Sgt70%3D 4448148 26000481
    • Zomer A, Maynard C, Verweij FJ, Kamermans A, Schafer R, Beerling E, et al. In Vivo imaging reveals extracellular vesicle-mediated phenocopying of metastatic behavior. Cell. 2015;161(5):1046-57.
    • (2015) Cell , vol.161 , Issue.5 , pp. 1046-1057
    • Zomer, A.1    Maynard, C.2    Verweij, F.J.3    Kamermans, A.4    Schafer, R.5    Beerling, E.6
  • 49
    • 84870911785 scopus 로고    scopus 로고
    • Docetaxel-resistance in prostate cancer: Evaluating associated phenotypic changes and potential for resistance transfer via exosomes
    • 1:CAS:528:DC%2BC38XhvFSks73N 3519481 23251413
    • Corcoran C, Rani S, O'Brien K, O'Neill A, Prencipe M, Sheikh R, et al. Docetaxel-resistance in prostate cancer: evaluating associated phenotypic changes and potential for resistance transfer via exosomes. PLoS One. 2012;7(12):e50999.
    • (2012) PLoS One , vol.7 , Issue.12 , pp. 50999
    • Corcoran, C.1    Rani, S.2    O'Brien, K.3    O'Neill, A.4    Prencipe, M.5    Sheikh, R.6
  • 50
    • 84930001098 scopus 로고    scopus 로고
    • Exosomal miR-221/222 enhances tamoxifen resistance in recipient ER-positive breast cancer cells
    • 1:CAS:528:DC%2BC2cXhtFCqtrrP 25007959
    • Wei Y, Lai X, Yu S, Chen S, Ma Y, Zhang Y, et al. Exosomal miR-221/222 enhances tamoxifen resistance in recipient ER-positive breast cancer cells. Breast Cancer Res Treat. 2014;147(2):423-31.
    • (2014) Breast Cancer Res Treat , vol.147 , Issue.2 , pp. 423-431
    • Wei, Y.1    Lai, X.2    Yu, S.3    Chen, S.4    Ma, Y.5    Zhang, Y.6
  • 51
    • 0043092308 scopus 로고    scopus 로고
    • Expulsion of small molecules in vesicles shed by cancer cells: Association with gene expression and chemosensitivity profiles
    • 1:CAS:528:DC%2BD3sXmtFekurg%3D 12907600
    • Shedden K, Xie XT, Chandaroy P, Chang YT, Rosania GR. Expulsion of small molecules in vesicles shed by cancer cells: association with gene expression and chemosensitivity profiles. Cancer Res. 2003;63(15):4331-7.
    • (2003) Cancer Res , vol.63 , Issue.15 , pp. 4331-4337
    • Shedden, K.1    Xie, X.T.2    Chandaroy, P.3    Chang, Y.T.4    Rosania, G.R.5
  • 52
    • 27644524811 scopus 로고    scopus 로고
    • Abnormal lysosomal trafficking and enhanced exosomal export of cisplatin in drug-resistant human ovarian carcinoma cells
    • 1:CAS:528:DC%2BD2MXhtFWhtLnK 16227410
    • Safaei R, Larson BJ, Cheng TC, Gibson MA, Otani S, Naerdemann W, et al. Abnormal lysosomal trafficking and enhanced exosomal export of cisplatin in drug-resistant human ovarian carcinoma cells. Mol Cancer Ther. 2005;4(10):1595-604.
    • (2005) Mol Cancer Ther , vol.4 , Issue.10 , pp. 1595-1604
    • Safaei, R.1    Larson, B.J.2    Cheng, T.C.3    Gibson, M.A.4    Otani, S.5    Naerdemann, W.6
  • 53
    • 33745615832 scopus 로고    scopus 로고
    • Melanosomal sequestration of cytotoxic drugs contributes to the intractability of malignant melanomas
    • 1:CAS:528:DC%2BD28XmvVajtLg%3D 1502551 16777967
    • Chen KG, Valencia JC, Lai B, Zhang G, Paterson JK, Rouzaud F, et al. Melanosomal sequestration of cytotoxic drugs contributes to the intractability of malignant melanomas. Proc Natl Acad Sci U S A. 2006;103(26):9903-7.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , Issue.26 , pp. 9903-9907
    • Chen, K.G.1    Valencia, J.C.2    Lai, B.3    Zhang, G.4    Paterson, J.K.5    Rouzaud, F.6
  • 54
    • 80053067140 scopus 로고    scopus 로고
    • Exosomal evasion of humoral immunotherapy in aggressive B-cell lymphoma modulated by ATP-binding cassette transporter A3
    • 1:CAS:528:DC%2BC3MXht1Gqt7zF 3174603 21873242
    • Aung T, Chapuy B, Vogel D, Wenzel D, Oppermann M, Lahmann M, et al. Exosomal evasion of humoral immunotherapy in aggressive B-cell lymphoma modulated by ATP-binding cassette transporter A3. Proc Natl Acad Sci U S A. 2011;108(37):15336-41.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , Issue.37 , pp. 15336-15341
    • Aung, T.1    Chapuy, B.2    Vogel, D.3    Wenzel, D.4    Oppermann, M.5    Lahmann, M.6
  • 55
    • 80052195983 scopus 로고    scopus 로고
    • Potential role of HER2-overexpressing exosomes in countering trastuzumab-based therapy
    • 1:CAS:528:DC%2BC3MXhsFartLvL 21465472
    • Ciravolo V, Huber V, Ghedini GC, Venturelli E, Bianchi F, Campiglio M, et al. Potential role of HER2-overexpressing exosomes in countering trastuzumab-based therapy. J Cell Physiol. 2012;227(2):658-67.
    • (2012) J Cell Physiol , vol.227 , Issue.2 , pp. 658-667
    • Ciravolo, V.1    Huber, V.2    Ghedini, G.C.3    Venturelli, E.4    Bianchi, F.5    Campiglio, M.6
  • 56
    • 79955548092 scopus 로고    scopus 로고
    • Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC
    • 1:CAS:528:DC%2BC3MXkvF2gs7c%3D 21293856
    • Battke C, Ruiss R, Welsch U, Wimberger P, Lang S, Jochum S, et al. Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC. Cancer Immunol Immunother. 2011;60(5):639-48.
    • (2011) Cancer Immunol Immunother , vol.60 , Issue.5 , pp. 639-648
    • Battke, C.1    Ruiss, R.2    Welsch, U.3    Wimberger, P.4    Lang, S.5    Jochum, S.6
  • 57
    • 34249792918 scopus 로고    scopus 로고
    • Tumor exosomes inhibit differentiation of bone marrow dendritic cells
    • 1:CAS:528:DC%2BD2sXlsVOmsrk%3D 17513735
    • Yu S, Liu C, Su K, Wang J, Liu Y, Zhang L, et al. Tumor exosomes inhibit differentiation of bone marrow dendritic cells. J Immunol. 2007;178(11):6867-75.
    • (2007) J Immunol , vol.178 , Issue.11 , pp. 6867-6875
    • Yu, S.1    Liu, C.2    Su, K.3    Wang, J.4    Liu, Y.5    Zhang, L.6
  • 58
    • 34547686145 scopus 로고    scopus 로고
    • Human tumor-derived exosomes selectively impair lymphocyte responses to interleukin-2
    • 1:CAS:528:DC%2BD2sXosVemtLc%3D 17671216
    • Clayton A, Mitchell JP, Court J, Mason MD, Tabi Z. Human tumor-derived exosomes selectively impair lymphocyte responses to interleukin-2. Cancer Res. 2007;67(15):7458-66.
    • (2007) Cancer Res , vol.67 , Issue.15 , pp. 7458-7466
    • Clayton, A.1    Mitchell, J.P.2    Court, J.3    Mason, M.D.4    Tabi, Z.5
  • 60
    • 84906212452 scopus 로고    scopus 로고
    • Tumor-derived exosomes promote tumor progression and T-cell dysfunction through the regulation of enriched exosomal microRNAs in human nasopharyngeal carcinoma
    • 4170615 24978137
    • Ye SB, Li ZL, Luo DH, Huang BJ, Chen YS, Zhang XS, et al. Tumor-derived exosomes promote tumor progression and T-cell dysfunction through the regulation of enriched exosomal microRNAs in human nasopharyngeal carcinoma. Oncotarget. 2014;5(14):5439-52.
    • (2014) Oncotarget , vol.5 , Issue.14 , pp. 5439-5452
    • Ye, S.B.1    Li, Z.L.2    Luo, D.H.3    Huang, B.J.4    Chen, Y.S.5    Zhang, X.S.6
  • 61
    • 64249115813 scopus 로고    scopus 로고
    • Induction of myeloid-derived suppressor cells by tumor exosomes
    • 1:CAS:528:DC%2BD1MXltlegu7s%3D 2757307 19235923
    • Xiang X, Poliakov A, Liu C, Liu Y, Deng ZB, Wang J, et al. Induction of myeloid-derived suppressor cells by tumor exosomes. Int J Cancer. 2009;124(11):2621-33.
    • (2009) Int J Cancer , vol.124 , Issue.11 , pp. 2621-2633
    • Xiang, X.1    Poliakov, A.2    Liu, C.3    Liu, Y.4    Deng, Z.B.5    Wang, J.6
  • 62
    • 77952042113 scopus 로고    scopus 로고
    • Contribution of MyD88 to the tumor exosome-mediated induction of myeloid derived suppressor cells
    • 1:CAS:528:DC%2BC3cXmvFSqurY%3D 2861113 20348242
    • Liu Y, Xiang X, Zhuang X, Zhang S, Liu C, Cheng Z, et al. Contribution of MyD88 to the tumor exosome-mediated induction of myeloid derived suppressor cells. Am J Pathol. 2010;176(5):2490-9.
    • (2010) Am J Pathol , vol.176 , Issue.5 , pp. 2490-2499
    • Liu, Y.1    Xiang, X.2    Zhuang, X.3    Zhang, S.4    Liu, C.5    Cheng, Z.6
  • 63
    • 76649097628 scopus 로고    scopus 로고
    • Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells
    • 1:CAS:528:DC%2BC3cXhsVOktL4%3D 2810085 20093776
    • Chalmin F, Ladoire S, Mignot G, Vincent J, Bruchard M, Remy-Martin JP, et al. Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells. J Clin Invest. 2010;120(2):457-71.
    • (2010) J Clin Invest , vol.120 , Issue.2 , pp. 457-471
    • Chalmin, F.1    Ladoire, S.2    Mignot, G.3    Vincent, J.4    Bruchard, M.5    Remy-Martin, J.P.6
  • 64
    • 84904630086 scopus 로고    scopus 로고
    • Macrophage immunomodulation by breast cancer-derived exosomes requires toll-like receptor 2-mediated activation of NF-kappaB
    • 1:CAS:528:DC%2BC2MXksVylsr4%3D 4102923 25034888
    • Chow A, Zhou W, Liu L, Fong MY, Champer J, Van Haute D, et al. Macrophage immunomodulation by breast cancer-derived exosomes requires toll-like receptor 2-mediated activation of NF-kappaB. Sci Rep. 2014;4:5750.
    • (2014) Sci Rep , vol.4 , pp. 5750
    • Chow, A.1    Zhou, W.2    Liu, L.3    Fong, M.Y.4    Champer, J.5    Van Haute, D.6
  • 65
    • 84931033158 scopus 로고    scopus 로고
    • Prostate tumor-derived exosomes down-regulate NKG2D expression on natural killer cells and CD8+ T cells: Mechanism of immune evasion
    • 4182531 25268476
    • Lundholm M, Schroder M, Nagaeva O, Baranov V, Widmark A, Mincheva-Nilsson L, et al. Prostate tumor-derived exosomes down-regulate NKG2D expression on natural killer cells and CD8+ T cells: mechanism of immune evasion. PLoS One. 2014;9(9):e108925.
    • (2014) PLoS One , vol.9 , Issue.9 , pp. 108925
    • Lundholm, M.1    Schroder, M.2    Nagaeva, O.3    Baranov, V.4    Widmark, A.5    Mincheva-Nilsson, L.6
  • 66
    • 78649958307 scopus 로고    scopus 로고
    • Cancer exosomes trigger fibroblast to myofibroblast differentiation
    • 1:CAS:528:DC%2BC3cXhsFamur3E 21098712
    • Webber J, Steadman R, Mason MD, Tabi Z, Clayton A. Cancer exosomes trigger fibroblast to myofibroblast differentiation. Cancer Res. 2010;70(23):9621-30.
    • (2010) Cancer Res , vol.70 , Issue.23 , pp. 9621-9630
    • Webber, J.1    Steadman, R.2    Mason, M.D.3    Tabi, Z.4    Clayton, A.5
  • 67
    • 84925446437 scopus 로고    scopus 로고
    • Differentiation of tumour-promoting stromal myofibroblasts by cancer exosomes
    • 1:CAS:528:DC%2BC2cXps1Cgsg%3D%3D 24441045
    • Webber JP, Spary LK, Sanders AJ, Chowdhury R, Jiang WG, Steadman R, et al. Differentiation of tumour-promoting stromal myofibroblasts by cancer exosomes. Oncogene. 2015;34(3):290-302.
    • (2015) Oncogene , vol.34 , Issue.3 , pp. 290-302
    • Webber, J.P.1    Spary, L.K.2    Sanders, A.J.3    Chowdhury, R.4    Jiang, W.G.5    Steadman, R.6
  • 68
    • 84871451335 scopus 로고    scopus 로고
    • Gastric cancer exosomes trigger differentiation of umbilical cord derived mesenchymal stem cells to carcinoma-associated fibroblasts through TGF-beta/Smad pathway
    • 1:CAS:528:DC%2BC3sXlsVGrtA%3D%3D 3527492 23285052
    • Gu J, Qian H, Shen L, Zhang X, Zhu W, Huang L, et al. Gastric cancer exosomes trigger differentiation of umbilical cord derived mesenchymal stem cells to carcinoma-associated fibroblasts through TGF-beta/Smad pathway. PLoS One. 2012;7(12):e52465.
    • (2012) PLoS One , vol.7 , Issue.12 , pp. 52465
    • Gu, J.1    Qian, H.2    Shen, L.3    Zhang, X.4    Zhu, W.5    Huang, L.6
  • 69
    • 84455171408 scopus 로고    scopus 로고
    • Exosomes from breast cancer cells can convert adipose tissue-derived mesenchymal stem cells into myofibroblast-like cells
    • 1:CAS:528:DC%2BC3MXhs1GksbfN 21904773
    • Cho JA, Park H, Lim EH, Lee KW. Exosomes from breast cancer cells can convert adipose tissue-derived mesenchymal stem cells into myofibroblast-like cells. Int J Oncol. 2012;40(1):130-8.
    • (2012) Int J Oncol , vol.40 , Issue.1 , pp. 130-138
    • Cho, J.A.1    Park, H.2    Lim, E.H.3    Lee, K.W.4
  • 70
    • 84908275360 scopus 로고    scopus 로고
    • Exosome transfer from stromal to breast cancer cells regulates therapy resistance pathways
    • 1:CAS:528:DC%2BC2cXhvVanur%2FM 25417103
    • Boelens MC, Wu TJ, Nabet BY, Xu B, Qiu Y, Yoon T, et al. Exosome transfer from stromal to breast cancer cells regulates therapy resistance pathways. Cell. 2014;159(3):499-513.
    • (2014) Cell , vol.159 , Issue.3 , pp. 499-513
    • Boelens, M.C.1    Wu, T.J.2    Nabet, B.Y.3    Xu, B.4    Qiu, Y.5    Yoon, T.6
  • 71
    • 84871602943 scopus 로고    scopus 로고
    • Cancer cells induced to express mesenchymal phenotype release exosome-like extracellular vesicles carrying tissue factor
    • 1:CAS:528:DC%2BC38XhvVOrt73J 3527943 23118232
    • Garnier D, Magnus N, Lee TH, Bentley V, Meehan B, Milsom C, et al. Cancer cells induced to express mesenchymal phenotype release exosome-like extracellular vesicles carrying tissue factor. J Biol Chem. 2012;287(52):43565-72.
    • (2012) J Biol Chem , vol.287 , Issue.52 , pp. 43565-43572
    • Garnier, D.1    Magnus, N.2    Lee, T.H.3    Bentley, V.4    Meehan, B.5    Milsom, C.6
  • 72
    • 45449093192 scopus 로고    scopus 로고
    • MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer
    • 1:CAS:528:DC%2BD1cXnvVOlu74%3D 18589210
    • Taylor DD, Gercel-Taylor C. MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. Gynecol Oncol. 2008;110(1):13-21.
    • (2008) Gynecol Oncol , vol.110 , Issue.1 , pp. 13-21
    • Taylor, D.D.1    Gercel-Taylor, C.2
  • 73
    • 84857968441 scopus 로고    scopus 로고
    • The majority of microRNAs detectable in serum and saliva is concentrated in exosomes
    • 1:CAS:528:DC%2BC38XktlSktrs%3D 3302865 22427800
    • Gallo A, Tandon M, Alevizos I, Illei GG. The majority of microRNAs detectable in serum and saliva is concentrated in exosomes. PLoS One. 2012;7(3):e30679.
    • (2012) PLoS One , vol.7 , Issue.3 , pp. 30679
    • Gallo, A.1    Tandon, M.2    Alevizos, I.3    Illei, G.G.4
  • 74
    • 84922194380 scopus 로고    scopus 로고
    • Circulating miRNAs in cancer: From detection to therapy
    • 1:CAS:528:DC%2BC2cXhtFyntL3F 4269921 25476853
    • Wang W, Chen Y. Circulating miRNAs in cancer: from detection to therapy. J Hematol Oncol. 2014;7(1):86.
    • (2014) J Hematol Oncol , vol.7 , Issue.1 , pp. 86
    • Wang, W.1    Chen, Y.2
  • 75
    • 57049103401 scopus 로고    scopus 로고
    • Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
    • 1:CAS:528:DC%2BD1cXhsVentbfI 3423894 19011622
    • Skog J, Wurdinger T, van Rijn S, Meijer DH, Gainche L, Sena-Esteves M, et al. Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nat Cell Biol. 2008;10(12):1470-6.
    • (2008) Nat Cell Biol , vol.10 , Issue.12 , pp. 1470-1476
    • Skog, J.1    Wurdinger, T.2    Van Rijn, S.3    Meijer, D.H.4    Gainche, L.5    Sena-Esteves, M.6
  • 77
    • 84891636580 scopus 로고    scopus 로고
    • Role of pancreatic cancer-derived exosomes in salivary biomarker development
    • 1:CAS:528:DC%2BC3sXhsVCltLnJ 3772238 23880764
    • Lau C, Kim Y, Chia D, Spielmann N, Eibl G, Elashoff D, et al. Role of pancreatic cancer-derived exosomes in salivary biomarker development. J Biol Chem. 2013;288(37):26888-97.
    • (2013) J Biol Chem , vol.288 , Issue.37 , pp. 26888-26897
    • Lau, C.1    Kim, Y.2    Chia, D.3    Spielmann, N.4    Eibl, G.5    Elashoff, D.6
  • 78
    • 67349142591 scopus 로고    scopus 로고
    • Prostate cancer-derived urine exosomes: A novel approach to biomarkers for prostate cancer
    • 1:CAS:528:DC%2BD1MXlslCht70%3D 2696767 19401683
    • Nilsson J, Skog J, Nordstrand A, Baranov V, Mincheva-Nilsson L, Breakefield XO, et al. Prostate cancer-derived urine exosomes: a novel approach to biomarkers for prostate cancer. Br J Cancer. 2009;100(10):1603-7.
    • (2009) Br J Cancer , vol.100 , Issue.10 , pp. 1603-1607
    • Nilsson, J.1    Skog, J.2    Nordstrand, A.3    Baranov, V.4    Mincheva-Nilsson, L.5    Breakefield, X.O.6
  • 79
    • 78650966289 scopus 로고    scopus 로고
    • Intracellular and extracellular microRNAs in breast cancer
    • 1:CAS:528:DC%2BC3MXitFSlu7w%3D 21059829
    • Corcoran C, Friel AM, Duffy MJ, Crown J, O'Driscoll L. Intracellular and extracellular microRNAs in breast cancer. Clin Chem. 2011;57(1):18-32.
    • (2011) Clin Chem , vol.57 , Issue.1 , pp. 18-32
    • Corcoran, C.1    Friel, A.M.2    Duffy, M.J.3    Crown, J.4    O'Driscoll, L.5
  • 80
    • 84874755851 scopus 로고    scopus 로고
    • Clinical impact of serum exosomal microRNA-21 as a clinical biomarker in human esophageal squamous cell carcinoma
    • 1:CAS:528:DC%2BC3sXjsFekur8%3D 23224754
    • Tanaka Y, Kamohara H, Kinoshita K, Kurashige J, Ishimoto T, Iwatsuki M, et al. Clinical impact of serum exosomal microRNA-21 as a clinical biomarker in human esophageal squamous cell carcinoma. Cancer. 2013;119(6):1159-67.
    • (2013) Cancer , vol.119 , Issue.6 , pp. 1159-1167
    • Tanaka, Y.1    Kamohara, H.2    Kinoshita, K.3    Kurashige, J.4    Ishimoto, T.5    Iwatsuki, M.6
  • 81
    • 84887441210 scopus 로고    scopus 로고
    • Extracellular vesicle-mediated transfer of a novel long noncoding RNA TUC339: A mechanism of intercellular signaling in human hepatocellular cancer
    • 1:CAS:528:DC%2BC2MXjt1Wru70%3D 3807642 24167654
    • Kogure T, Yan IK, Lin WL, Patel T. Extracellular vesicle-mediated transfer of a novel long noncoding RNA TUC339: a mechanism of intercellular signaling in human hepatocellular cancer. Genes Cancer. 2013;4(7-8):261-72.
    • (2013) Genes Cancer , vol.4 , Issue.7-8 , pp. 261-272
    • Kogure, T.1    Yan, I.K.2    Lin, W.L.3    Patel, T.4
  • 82
    • 84901398883 scopus 로고    scopus 로고
    • Extracellular vesicle-mediated transfer of long non-coding RNA ROR modulates chemosensitivity in human hepatocellular cancer
    • 1:CAS:528:DC%2BC2cXht1ymsrzO 4050189 24918061
    • Takahashi K, Yan IK, Kogure T, Haga H, Patel T. Extracellular vesicle-mediated transfer of long non-coding RNA ROR modulates chemosensitivity in human hepatocellular cancer. FEBS Open Bio. 2014;4:458-67.
    • (2014) FEBS Open Bio , vol.4 , pp. 458-467
    • Takahashi, K.1    Yan, I.K.2    Kogure, T.3    Haga, H.4    Patel, T.5
  • 83
    • 84930889309 scopus 로고    scopus 로고
    • Plasma long noncoding RNA protected by exosomes as a potential stable biomarker for gastric cancer
    • 1:CAS:528:DC%2BC2cXhvFGgtrjF 25391424
    • Li Q, Shao Y, Zhang X, Zheng T, Miao M, Qin L, et al. Plasma long noncoding RNA protected by exosomes as a potential stable biomarker for gastric cancer. Tumour Biol. 2015;36(3):2007-12.
    • (2015) Tumour Biol , vol.36 , Issue.3 , pp. 2007-2012
    • Li, Q.1    Shao, Y.2    Zhang, X.3    Zheng, T.4    Miao, M.5    Qin, L.6
  • 84
    • 84905318644 scopus 로고    scopus 로고
    • Combined detection of serum exosomal miR-21 and HOTAIR as diagnostic and prognostic biomarkers for laryngeal squamous cell carcinoma
    • 25099764
    • Wang J, Zhou Y, Lu J, Sun Y, Xiao H, Liu M, et al. Combined detection of serum exosomal miR-21 and HOTAIR as diagnostic and prognostic biomarkers for laryngeal squamous cell carcinoma. Med Oncol. 2014;31(9):148.
    • (2014) Med Oncol , vol.31 , Issue.9 , pp. 148
    • Wang, J.1    Zhou, Y.2    Lu, J.3    Sun, Y.4    Xiao, H.5    Liu, M.6
  • 85
    • 84906098610 scopus 로고    scopus 로고
    • Dendritic cell-derived exosomes as immunotherapies in the fight against cancer
    • 1:CAS:528:DC%2BC2cXhtFyqs77N 25049431
    • Pitt JM, Charrier M, Viaud S, Andre F, Besse B, Chaput N, et al. Dendritic cell-derived exosomes as immunotherapies in the fight against cancer. J Immunol. 2014;193(3):1006-11.
    • (2014) J Immunol , vol.193 , Issue.3 , pp. 1006-1011
    • Pitt, J.M.1    Charrier, M.2    Viaud, S.3    Andre, F.4    Besse, B.5    Chaput, N.6
  • 86
    • 0031863853 scopus 로고    scopus 로고
    • Eradication of established murine tumors using a novel cell-free vaccine: Dendritic cell-derived exosomes
    • 1:CAS:528:DyaK1cXjtFGqsbc%3D 9585234
    • Zitvogel L, Regnault A, Lozier A, Wolfers J, Flament C, Tenza D, et al. Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell-derived exosomes. Nat Med. 1998;4(5):594-600.
    • (1998) Nat Med , vol.4 , Issue.5 , pp. 594-600
    • Zitvogel, L.1    Regnault, A.2    Lozier, A.3    Wolfers, J.4    Flament, C.5    Tenza, D.6
  • 87
    • 20244373139 scopus 로고    scopus 로고
    • Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming
    • 1:CAS:528:DC%2BD3MXhvVOksrY%3D 11231627
    • Wolfers J, Lozier A, Raposo G, Regnault A, Thery C, Masurier C, et al. Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming. Nat Med. 2001;7(3):297-303.
    • (2001) Nat Med , vol.7 , Issue.3 , pp. 297-303
    • Wolfers, J.1    Lozier, A.2    Raposo, G.3    Regnault, A.4    Thery, C.5    Masurier, C.6
  • 88
    • 79952115112 scopus 로고    scopus 로고
    • The application of exosomes as a nanoscale cancer vaccine
    • 1:CAS:528:DC%2BC3cXhsVGjt7fI 2990382 21116329
    • Tan A, De La Pena H, Seifalian AM. The application of exosomes as a nanoscale cancer vaccine. Int J Nanomedicine. 2010;5:889-900.
    • (2010) Int J Nanomedicine , vol.5 , pp. 889-900
    • Tan, A.1    De La Pena, H.2    Seifalian, A.M.3
  • 89
    • 84862734041 scopus 로고    scopus 로고
    • Exosome removal as a therapeutic adjuvant in cancer
    • 1:CAS:528:DC%2BC38Xhsl2jt7bK 3441244 22738135
    • Marleau AM, Chen CS, Joyce JA, Tullis RH. Exosome removal as a therapeutic adjuvant in cancer. J Transl Med. 2012;10:134.
    • (2012) J Transl Med , vol.10 , pp. 134
    • Marleau, A.M.1    Chen, C.S.2    Joyce, J.A.3    Tullis, R.H.4
  • 92
    • 84896700643 scopus 로고    scopus 로고
    • Microvesicle-mediated delivery of transforming growth factor beta1 siRNA for the suppression of tumor growth in mice
    • 1:CAS:528:DC%2BC2cXivFyguro%3D 24565517
    • Zhang Y, Li L, Yu J, Zhu D, Li X, Gu H, et al. Microvesicle-mediated delivery of transforming growth factor beta1 siRNA for the suppression of tumor growth in mice. Biomaterials. 2014;35(14):4390-400.
    • (2014) Biomaterials , vol.35 , Issue.14 , pp. 4390-4400
    • Zhang, Y.1    Li, L.2    Yu, J.3    Zhu, D.4    Li, X.5    Gu, H.6
  • 93
    • 79953858598 scopus 로고    scopus 로고
    • Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
    • 1:CAS:528:DC%2BC3MXjsVKqsLw%3D 21423189
    • Alvarez-Erviti L, Seow Y, Yin H, Betts C, Lakhal S, Wood MJ. Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes. Nat Biotechnol. 2011;29(4):341-5.
    • (2011) Nat Biotechnol , vol.29 , Issue.4 , pp. 341-345
    • Alvarez-Erviti, L.1    Seow, Y.2    Yin, H.3    Betts, C.4    Lakhal, S.5    Wood, M.J.6
  • 94
    • 84891372823 scopus 로고    scopus 로고
    • A doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapy
    • 1:CAS:528:DC%2BC3sXhvFGrsbzJ 24345736
    • Tian Y, Li S, Song J, Ji T, Zhu M, Anderson GJ, et al. A doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapy. Biomaterials. 2014;35(7):2383-90.
    • (2014) Biomaterials , vol.35 , Issue.7 , pp. 2383-2390
    • Tian, Y.1    Li, S.2    Song, J.3    Ji, T.4    Zhu, M.5    Anderson, G.J.6
  • 96
    • 84907228576 scopus 로고    scopus 로고
    • Paclitaxel is incorporated by mesenchymal stromal cells and released in exosomes that inhibit in vitro tumor growth: A new approach for drug delivery
    • 1:CAS:528:DC%2BC2cXht1Ghu7fM 25084218
    • Pascucci L, Cocce V, Bonomi A, Ami D, Ceccarelli P, Ciusani E, et al. Paclitaxel is incorporated by mesenchymal stromal cells and released in exosomes that inhibit in vitro tumor growth: a new approach for drug delivery. J Control Release. 2014;192:262-70.
    • (2014) J Control Release , vol.192 , pp. 262-270
    • Pascucci, L.1    Cocce, V.2    Bonomi, A.3    Ami, D.4    Ceccarelli, P.5    Ciusani, E.6
  • 97
    • 84874031607 scopus 로고    scopus 로고
    • Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS
    • 3567858 23161513
    • Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, et al. Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Mol Cell Proteomics. 2013;12(2):343-55.
    • (2013) Mol Cell Proteomics , vol.12 , Issue.2 , pp. 343-355
    • Demory Beckler, M.1    Higginbotham, J.N.2    Franklin, J.L.3    Ham, A.J.4    Halvey, P.J.5    Imasuen, I.E.6
  • 98
    • 84929012795 scopus 로고    scopus 로고
    • The alphavbeta6 integrin is transferred intercellularly via exosomes
    • 1:CAS:528:DC%2BC2MXjtlGjtbw%3D 25568317
    • Fedele C, Singh A, Zerlanko BJ, Iozzo RV, Languino LR. The alphavbeta6 integrin is transferred intercellularly via exosomes. J Biol Chem. 2015;290(8):4545-51.
    • (2015) J Biol Chem , vol.290 , Issue.8 , pp. 4545-4551
    • Fedele, C.1    Singh, A.2    Zerlanko, B.J.3    Iozzo, R.V.4    Languino, L.R.5
  • 99
  • 100
    • 84890149349 scopus 로고    scopus 로고
    • Induction and transport of Wnt5a during macrophage-induced malignant invasion is mediated by two types of extracellular vesicles
    • 3875769 24185202
    • Menck K, Klemm F, Gross JC, Pukrop T, Wenzel D, Binder C. Induction and transport of Wnt5a during macrophage-induced malignant invasion is mediated by two types of extracellular vesicles. Oncotarget. 2013;4(11):2057-66.
    • (2013) Oncotarget , vol.4 , Issue.11 , pp. 2057-2066
    • Menck, K.1    Klemm, F.2    Gross, J.C.3    Pukrop, T.4    Wenzel, D.5    Binder, C.6
  • 101
    • 79960516623 scopus 로고    scopus 로고
    • Cancer exosomes express CD39 and CD73, which suppress T cells through adenosine production
    • 1:CAS:528:DC%2BC3MXos1eiu74%3D 21677139
    • Clayton A, Al-Taei S, Webber J, Mason MD, Tabi Z. Cancer exosomes express CD39 and CD73, which suppress T cells through adenosine production. J Immunol. 2011;187(2):676-83.
    • (2011) J Immunol , vol.187 , Issue.2 , pp. 676-683
    • Clayton, A.1    Al-Taei, S.2    Webber, J.3    Mason, M.D.4    Tabi, Z.5
  • 102
    • 84921709757 scopus 로고    scopus 로고
    • Cancer exosomes trigger mesenchymal stem cell differentiation into pro-angiogenic and pro-invasive myofibroblasts
    • 4359250 25596732
    • Chowdhury R, Webber JP, Gurney M, Mason MD, Tabi Z, Clayton A. Cancer exosomes trigger mesenchymal stem cell differentiation into pro-angiogenic and pro-invasive myofibroblasts. Oncotarget. 2015;6(2):715-31.
    • (2015) Oncotarget , vol.6 , Issue.2 , pp. 715-731
    • Chowdhury, R.1    Webber, J.P.2    Gurney, M.3    Mason, M.D.4    Tabi, Z.5    Clayton, A.6
  • 103
    • 47249144117 scopus 로고    scopus 로고
    • Human tumor-derived exosomes down-modulate NKG2D expression
    • 1:CAS:528:DC%2BD1cXmtVantbo%3D 18490724
    • Clayton A, Mitchell JP, Court J, Linnane S, Mason MD, Tabi Z. Human tumor-derived exosomes down-modulate NKG2D expression. J Immunol. 2008;180(11):7249-58.
    • (2008) J Immunol , vol.180 , Issue.11 , pp. 7249-7258
    • Clayton, A.1    Mitchell, J.P.2    Court, J.3    Linnane, S.4    Mason, M.D.5    Tabi, Z.6
  • 104
    • 76549099879 scopus 로고    scopus 로고
    • Natural killer cell cytotoxicity is suppressed by exposure to the human NKG2D ligand MICA∗008 that is shed by tumor cells in exosomes
    • 1:CAS:528:DC%2BC3cXltlWktQ%3D%3D 2817492 20068167
    • Ashiru O, Boutet P, Fernandez-Messina L, Aguera-Gonzalez S, Skepper JN, Vales-Gomez M, et al. Natural killer cell cytotoxicity is suppressed by exposure to the human NKG2D ligand MICA∗008 that is shed by tumor cells in exosomes. Cancer Res. 2010;70(2):481-9.
    • (2010) Cancer Res , vol.70 , Issue.2 , pp. 481-489
    • Ashiru, O.1    Boutet, P.2    Fernandez-Messina, L.3    Aguera-Gonzalez, S.4    Skepper, J.N.5    Vales-Gomez, M.6
  • 105
    • 84988596427 scopus 로고    scopus 로고
    • Mast cell exosomes promote lung adenocarcinoma cell proliferation - Role of KIT-stem cell factor signaling
    • 4206705 25311367
    • Xiao H, Lasser C, Shelke GV, Wang J, Radinger M, Lunavat TR, et al. Mast cell exosomes promote lung adenocarcinoma cell proliferation - role of KIT-stem cell factor signaling. Cell Commun Signal. 2014;12:64.
    • (2014) Cell Commun Signal , vol.12 , pp. 64
    • Xiao, H.1    Lasser, C.2    Shelke, G.V.3    Wang, J.4    Radinger, M.5    Lunavat, T.R.6
  • 106
    • 84921395983 scopus 로고    scopus 로고
    • Exosomal Hsp70 mediates immunosuppressive activity of the myeloid-derived suppressor cells via phosphorylation of Stat3
    • 25603952
    • Diao J, Yang X, Song X, Chen S, He Y, Wang Q, et al. Exosomal Hsp70 mediates immunosuppressive activity of the myeloid-derived suppressor cells via phosphorylation of Stat3. Med Oncol. 2015;32(2):453.
    • (2015) Med Oncol , vol.32 , Issue.2 , pp. 453
    • Diao, J.1    Yang, X.2    Song, X.3    Chen, S.4    He, Y.5    Wang, Q.6
  • 107
    • 84930391354 scopus 로고    scopus 로고
    • Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue
    • doi:gutjnl-2014-308350
    • Sagar G, Sah RP, Javeed N, Dutta SK, Smyrk TC, Lau JS, et al. Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue. Gut 2015, doi:gutjnl-2014-308350
    • (2015) Gut
    • Sagar, G.1    Sah, R.P.2    Javeed, N.3    Dutta, S.K.4    Smyrk, T.C.5    Lau, J.S.6
  • 108
    • 84928779693 scopus 로고    scopus 로고
    • Enterobacteria-secreted particles induce production of exosome-like S1P-containing particles by intestinal epithelium to drive Th17-mediated tumorigenesis
    • Deng Z, Mu J, Tseng M, Wattenberg B, Zhuang X, Egilmez NK, et al. Enterobacteria-secreted particles induce production of exosome-like S1P-containing particles by intestinal epithelium to drive Th17-mediated tumorigenesis. Nat Commun. 2012;6:6956.
    • (2012) Nat Commun , vol.6 , pp. 6956
    • Deng, Z.1    Mu, J.2    Tseng, M.3    Wattenberg, B.4    Zhuang, X.5    Egilmez, N.K.6
  • 109
    • 84866093563 scopus 로고    scopus 로고
    • Tumour-secreted miR-9 promotes endothelial cell migration and angiogenesis by activating the JAK-STAT pathway
    • 1:CAS:528:DC%2BC38XpvVSnt7o%3D 3433782 22773185
    • Zhuang G, Wu X, Jiang Z, Kasman I, Yao J, Guan Y, et al. Tumour-secreted miR-9 promotes endothelial cell migration and angiogenesis by activating the JAK-STAT pathway. EMBO J. 2012;31(17):3513-23.
    • (2012) EMBO J , vol.31 , Issue.17 , pp. 3513-3523
    • Zhuang, G.1    Wu, X.2    Jiang, Z.3    Kasman, I.4    Yao, J.5    Guan, Y.6
  • 110
    • 84934939517 scopus 로고    scopus 로고
    • Exosome-mediated transfer of miR-10b promotes cell invasion in breast cancer
    • 1:CAS:528:DC%2BC2cXitVOhtb%2FI 4258287 25428807
    • Singh R, Pochampally R, Watabe K, Lu Z, Mo YY. Exosome-mediated transfer of miR-10b promotes cell invasion in breast cancer. Mol Cancer. 2014;13:256.
    • (2014) Mol Cancer , vol.13 , pp. 256
    • Singh, R.1    Pochampally, R.2    Watabe, K.3    Lu, Z.4    Mo, Y.Y.5
  • 111
    • 84930172395 scopus 로고    scopus 로고
    • Exosomes from drug-resistant breast cancer cells transmit chemoresistance by a horizontal transfer of microRNAs
    • 3989268 24740415
    • Chen WX, Liu XM, Lv MM, Chen L, Zhao JH, Zhong SL, et al. Exosomes from drug-resistant breast cancer cells transmit chemoresistance by a horizontal transfer of microRNAs. PLoS One. 2014;9(4):e95240.
    • (2014) PLoS One , vol.9 , Issue.4 , pp. 95240
    • Chen, W.X.1    Liu, X.M.2    Lv, M.M.3    Chen, L.4    Zhao, J.H.5    Zhong, S.L.6
  • 112
    • 80053309537 scopus 로고    scopus 로고
    • Intercellular nanovesicle-mediated microRNA transfer: A mechanism of environmental modulation of hepatocellular cancer cell growth
    • 1:CAS:528:DC%2BC3MXht1amtbzF 3310362 21721029
    • Kogure T, Lin WL, Yan IK, Braconi C, Patel T. Intercellular nanovesicle-mediated microRNA transfer: a mechanism of environmental modulation of hepatocellular cancer cell growth. Hepatology. 2011;54(4):1237-48.
    • (2011) Hepatology , vol.54 , Issue.4 , pp. 1237-1248
    • Kogure, T.1    Lin, W.L.2    Yan, I.K.3    Braconi, C.4    Patel, T.5
  • 113
    • 84923194150 scopus 로고    scopus 로고
    • Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis
    • 1:CAS:528:DC%2BC2MXhsVehsbg%3D 25621950
    • Fong MY, Zhou W, Liu L, Alontaga AY, Chandra M, Ashby J, et al. Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis. Nat Cell Biol. 2015;17(2):183-94.
    • (2015) Nat Cell Biol , vol.17 , Issue.2 , pp. 183-194
    • Fong, M.Y.1    Zhou, W.2    Liu, L.3    Alontaga, A.Y.4    Chandra, M.5    Ashby, J.6
  • 114
    • 84929603438 scopus 로고    scopus 로고
    • Endothelial exosomes contribute to the antitumor response during breast cancer neoadjuvant chemotherapy via microRNA transfer
    • 25860935
    • Bovy N, Blomme B, Freres P, Dederen S, Nivelles O, Lion M, et al. Endothelial exosomes contribute to the antitumor response during breast cancer neoadjuvant chemotherapy via microRNA transfer. Oncotarget. 2015;6(12):10253-66.
    • (2015) Oncotarget , vol.6 , Issue.12 , pp. 10253-10266
    • Bovy, N.1    Blomme, B.2    Freres, P.3    Dederen, S.4    Nivelles, O.5    Lion, M.6
  • 115
    • 84939980068 scopus 로고    scopus 로고
    • Targeting exosomes from preadipocytes inhibits preadipocyte to cancer stem cell signaling in early-stage breast cancer
    • 25783182
    • Gernapudi R, Yao Y, Zhang Y, Wolfson B, Roy S, Duru N, et al. Targeting exosomes from preadipocytes inhibits preadipocyte to cancer stem cell signaling in early-stage breast cancer. Breast Cancer Res Treat. 2015;150(3):685-95.
    • (2015) Breast Cancer Res Treat , vol.150 , Issue.3 , pp. 685-695
    • Gernapudi, R.1    Yao, Y.2    Zhang, Y.3    Wolfson, B.4    Roy, S.5    Duru, N.6
  • 116
    • 79952219931 scopus 로고    scopus 로고
    • Gap junction-mediated import of microRNA from bone marrow stromal cells can elicit cell cycle quiescence in breast cancer cells
    • 1:CAS:528:DC%2BC3MXisFCgu7k%3D 21343399
    • Lim PK, Bliss SA, Patel SA, Taborga M, Dave MA, Gregory LA, et al. Gap junction-mediated import of microRNA from bone marrow stromal cells can elicit cell cycle quiescence in breast cancer cells. Cancer Res. 2011;71(5):1550-60.
    • (2011) Cancer Res , vol.71 , Issue.5 , pp. 1550-1560
    • Lim, P.K.1    Bliss, S.A.2    Patel, S.A.3    Taborga, M.4    Dave, M.A.5    Gregory, L.A.6
  • 117
    • 84905487789 scopus 로고    scopus 로고
    • Isolation and characterization of CD34+ blast-derived exosomes in acute myeloid leukemia
    • 4122364 25093329
    • Hong CS, Muller L, Boyiadzis M, Whiteside TL. Isolation and characterization of CD34+ blast-derived exosomes in acute myeloid leukemia. PLoS One. 2014;9(8):e103310.
    • (2014) PLoS One , vol.9 , Issue.8 , pp. 103310
    • Hong, C.S.1    Muller, L.2    Boyiadzis, M.3    Whiteside, T.L.4
  • 118
    • 84904253489 scopus 로고    scopus 로고
    • Bladder cancer exosomes contain EDIL-3/Del1 and facilitate cancer progression
    • 1:CAS:528:DC%2BC2cXhtVamsL7O 24530986
    • Beckham CJ, Olsen J, Yin PN, Wu CH, Ting HJ, Hagen FK, et al. Bladder cancer exosomes contain EDIL-3/Del1 and facilitate cancer progression. J Urol. 2014;192(2):583-92.
    • (2014) J Urol , vol.192 , Issue.2 , pp. 583-592
    • Beckham, C.J.1    Olsen, J.2    Yin, P.N.3    Wu, C.H.4    Ting, H.J.5    Hagen, F.K.6
  • 119
    • 84923699297 scopus 로고    scopus 로고
    • Increased serum levels of circulating exosomal microRNA-373 in receptor-negative breast cancer patients
    • 4259427 25333260
    • Eichelser C, Stuckrath I, Muller V, Milde-Langosch K, Wikman H, Pantel K, et al. Increased serum levels of circulating exosomal microRNA-373 in receptor-negative breast cancer patients. Oncotarget. 2014;5(20):9650-63.
    • (2014) Oncotarget , vol.5 , Issue.20 , pp. 9650-9663
    • Eichelser, C.1    Stuckrath, I.2    Muller, V.3    Milde-Langosch, K.4    Wikman, H.5    Pantel, K.6
  • 120
    • 84892171579 scopus 로고    scopus 로고
    • Increased exosomal microRNA-21 and microRNA-146a levels in the cervicovaginal lavage specimens of patients with cervical cancer
    • 3907836 24406730
    • Liu J, Sun H, Wang X, Yu Q, Li S, Yu X, et al. Increased exosomal microRNA-21 and microRNA-146a levels in the cervicovaginal lavage specimens of patients with cervical cancer. Int J Mol Sci. 2014;15(1):758-73.
    • (2014) Int J Mol Sci , vol.15 , Issue.1 , pp. 758-773
    • Liu, J.1    Sun, H.2    Wang, X.3    Yu, Q.4    Li, S.5    Yu, X.6
  • 121
  • 122
    • 84920937459 scopus 로고    scopus 로고
    • Ultra-sensitive liquid biopsy of circulating extracellular vesicles using ExoScreen
    • 3988821 24710016
    • Yoshioka Y, Kosaka N, Konishi Y, Ohta H, Okamoto H, Sonoda H, et al. Ultra-sensitive liquid biopsy of circulating extracellular vesicles using ExoScreen. Nat Commun. 2014;5:3591.
    • (2014) Nat Commun , vol.5 , pp. 3591
    • Yoshioka, Y.1    Kosaka, N.2    Konishi, Y.3    Ohta, H.4    Okamoto, H.5    Sonoda, H.6
  • 123
  • 124
    • 84964240625 scopus 로고    scopus 로고
    • Identification of a bona fide microRNA biomarker in serum exosomes that predicts hepatocellular carcinoma recurrence after liver transplantation
    • 1:CAS:528:DC%2BC2MXit1antbg%3D 25584485
    • Sugimachi K, Matsumura T, Hirata H, Uchi R, Ueda M, Ueo H, et al. Identification of a bona fide microRNA biomarker in serum exosomes that predicts hepatocellular carcinoma recurrence after liver transplantation. Br J Cancer. 2015;112(3):532-8.
    • (2015) Br J Cancer , vol.112 , Issue.3 , pp. 532-538
    • Sugimachi, K.1    Matsumura, T.2    Hirata, H.3    Uchi, R.4    Ueda, M.5    Ueo, H.6
  • 125
    • 84902176122 scopus 로고    scopus 로고
    • Expression of serum exosomal microRNA-21 in human hepatocellular carcinoma
    • 4052145 24963487
    • Wang H, Hou L, Li A, Duan Y, Gao H, Song X. Expression of serum exosomal microRNA-21 in human hepatocellular carcinoma. Biomed Res Int. 2014;2014:864894.
    • (2014) Biomed Res Int , vol.2014 , pp. 864894
    • Wang, H.1    Hou, L.2    Li, A.3    Duan, Y.4    Gao, H.5    Song, X.6
  • 126
    • 79960728743 scopus 로고    scopus 로고
    • Proteomic identification of exosomal LRG1: A potential urinary biomarker for detecting NSCLC
    • 1:CAS:528:DC%2BC3MXpt1Gisbc%3D 21557262
    • Li Y, Zhang Y, Qiu F, Qiu Z. Proteomic identification of exosomal LRG1: a potential urinary biomarker for detecting NSCLC. Electrophoresis. 2011;32(15):1976-83.
    • (2011) Electrophoresis , vol.32 , Issue.15 , pp. 1976-1983
    • Li, Y.1    Zhang, Y.2    Qiu, F.3    Qiu, Z.4
  • 127
    • 65449117971 scopus 로고    scopus 로고
    • High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients
    • 2667632 19381331
    • Logozzi M, De Milito A, Lugini L, Borghi M, Calabro L, Spada M, et al. High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients. PLoS One. 2009;4(4):e5219.
    • (2009) PLoS One , vol.4 , Issue.4 , pp. 5219
    • Logozzi, M.1    De Milito, A.2    Lugini, L.3    Borghi, M.4    Calabro, L.5    Spada, M.6
  • 128
    • 61849139471 scopus 로고    scopus 로고
    • Blood diffusion and Th1-suppressive effects of galectin-9-containing exosomes released by Epstein-Barr virus-infected nasopharyngeal carcinoma cells
    • 1:CAS:528:DC%2BD1MXivVaqsbk%3D 19005181
    • Klibi J, Niki T, Riedel A, Pioche-Durieu C, Souquere S, Rubinstein E, et al. Blood diffusion and Th1-suppressive effects of galectin-9-containing exosomes released by Epstein-Barr virus-infected nasopharyngeal carcinoma cells. Blood. 2009;113(9):1957-66.
    • (2009) Blood , vol.113 , Issue.9 , pp. 1957-1966
    • Klibi, J.1    Niki, T.2    Riedel, A.3    Pioche-Durieu, C.4    Souquere, S.5    Rubinstein, E.6
  • 130
    • 84924874243 scopus 로고    scopus 로고
    • Combined evaluation of a panel of protein and miRNA serum-exosome biomarkers for pancreatic cancer diagnosis increases sensitivity and specificity
    • 1:CAS:528:DC%2BC2cXhvF2jsrnP 25388097
    • Madhavan B, Yue S, Galli U, Rana S, Gross W, Muller M, et al. Combined evaluation of a panel of protein and miRNA serum-exosome biomarkers for pancreatic cancer diagnosis increases sensitivity and specificity. Int J Cancer. 2015;136(11):2616-27.
    • (2015) Int J Cancer , vol.136 , Issue.11 , pp. 2616-2627
    • Madhavan, B.1    Yue, S.2    Galli, U.3    Rana, S.4    Gross, W.5    Muller, M.6
  • 131
    • 84880823162 scopus 로고    scopus 로고
    • Regulation of the tumor suppressor PTEN through exosomes: A diagnostic potential for prostate cancer
    • 1:CAS:528:DC%2BC3sXht1Cmtr3F 3723640 23936141
    • Gabriel K, Ingram A, Austin R, Kapoor A, Tang D, Majeed F, et al. Regulation of the tumor suppressor PTEN through exosomes: a diagnostic potential for prostate cancer. PLoS One. 2013;8(7):e70047.
    • (2013) PLoS One , vol.8 , Issue.7 , pp. 70047
    • Gabriel, K.1    Ingram, A.2    Austin, R.3    Kapoor, A.4    Tang, D.5    Majeed, F.6
  • 132
    • 84867602816 scopus 로고    scopus 로고
    • Plasma-derived exosomal survivin, a plausible biomarker for early detection of prostate cancer
    • 1:CAS:528:DC%2BC38Xhs1WhtbrP 3473028 23091600
    • Khan S, Jutzy JM, Valenzuela MM, Turay D, Aspe JR, Ashok A, et al. Plasma-derived exosomal survivin, a plausible biomarker for early detection of prostate cancer. PLoS One. 2012;7(10):e46737.
    • (2012) PLoS One , vol.7 , Issue.10 , pp. 46737
    • Khan, S.1    Jutzy, J.M.2    Valenzuela, M.M.3    Turay, D.4    Aspe, J.R.5    Ashok, A.6
  • 134
    • 84924372715 scopus 로고    scopus 로고
    • Exosomal miR-1290 and miR-375 as prognostic markers in castration-resistant prostate cancer
    • 1:CAS:528:DC%2BC2cXhtlahsbnE 25129854
    • Huang X, Yuan T, Liang M, Du M, Xia S, Dittmar R, et al. Exosomal miR-1290 and miR-375 as prognostic markers in castration-resistant prostate cancer. Eur Urol. 2015;67(1):33-41.
    • (2015) Eur Urol , vol.67 , Issue.1 , pp. 33-41
    • Huang, X.1    Yuan, T.2    Liang, M.3    Du, M.4    Xia, S.5    Dittmar, R.6
  • 135
    • 84936760760 scopus 로고    scopus 로고
    • Exosomal lncRNA-p21 levels may help to distinguish prostate cancer from benign disease
    • 4422020 25999983
    • Isin M, Uysaler E, Ozgur E, Koseoglu H, Sanli O, Yucel OB, et al. Exosomal lncRNA-p21 levels may help to distinguish prostate cancer from benign disease. Front Genet. 2015;6:168.
    • (2015) Front Genet , vol.6 , pp. 168
    • Isin, M.1    Uysaler, E.2    Ozgur, E.3    Koseoglu, H.4    Sanli, O.5    Yucel, O.B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.