Exosome-mediated crosstalk between chronic myelogenous leukemia cells and human bone marrow stromal cells triggers an Interleukin 8-dependent survival of leukemia cells

Cancer Letters

Volumn 348, Issue 1-2, 2014, Pages 71-76

  Corrado, Chiara ^a   Raimondo, Stefania ^a   Saieva, Laura ^a   Flugy, Anna Maria ^a   De Leo, Giacomo ^a   Alessandro, Riccardo ^a  

^a UNIVERSITY OF PALERMO   (Italy)

Author keywords

Bone marrow stromal cells; Chronic myelogenous leukemia; Exosomes; Interleukin 8; Tumour microenvironment

Indexed keywords

CHEMOKINE RECEPTOR CXCR1; CHEMOKINE RECEPTOR CXCR2; INTERLEUKIN 8; RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW STROMAL CELL; CELL ADHESION; CELL MIGRATION; CELL STIMULATION; CELL SURVIVAL; CHRONIC MYELOID LEUKEMIA; COLONY FORMATION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXOSOME; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LEUKEMIA CELL; LEUKEMIA CELL LINE; MALE; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; SIGNAL TRANSDUCTION; STROMA CELL; TUMOR XENOGRAFT; WESTERN BLOTTING;

BONE MARROW STROMAL CELLS; CHRONIC MYELOGENOUS LEUKEMIA; EXOSOMES; INTERLEUKIN 8; TUMOUR MICROENVIRONMENT;

ANIMALS; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; CELL SURVIVAL; EXOSOMES; HETEROGRAFTS; HUMANS; INTERLEUKIN-8; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; MALE; MESENCHYMAL STROMAL CELLS; MICE; MICE, INBRED NOD; MICE, SCID; PARACRINE COMMUNICATION; PHENOTYPE; SIGNAL TRANSDUCTION; STEM CELL NICHE; TUMOR MICROENVIRONMENT; UP-REGULATION;

EID: 84900505110     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2014.03.009     Document Type: Article

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