-
1
-
-
35348870368
-
Stromogenic prostatic carcinoma pattern (carcinomas with reactive stromal grade 3) in needle biopsies predicts biochemical recurrence-free survival in patients after radical prostatectomy
-
Yanagisawa N, Li R, Rowley D, Liu H, Kadmon D, Miles BJ et al. Stromogenic prostatic carcinoma pattern (carcinomas with reactive stromal grade 3) in needle biopsies predicts biochemical recurrence-free survival in patients after radical prostatectomy. Hum Pathol 2007; 38: 1611-1620.
-
(2007)
Hum Pathol
, vol.38
, pp. 1611-1620
-
-
Yanagisawa, N.1
Li, R.2
Rowley, D.3
Liu, H.4
Kadmon, D.5
Miles, B.J.6
-
2
-
-
78650563018
-
Autocrine TGF-beta and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts
-
Kojima Y, Acar A, Eaton EN, Mellody KT, Scheel C, Ben-Porath I et al. Autocrine TGF-beta and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts. Proc Natl Acad Sci 2010; 107: 20009-20014.
-
(2010)
Proc Natl Acad Sci
, vol.107
, pp. 20009-20014
-
-
Kojima, Y.1
Acar, A.2
Eaton, E.N.3
Mellody, K.T.4
Scheel, C.5
Ben-Porath, I.6
-
3
-
-
0033215242
-
Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium
-
Olumi AF, Grossfeld GD, Hayward SW, Carroll PR, Tlsty TD, Cunha GR. Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium. Cancer Res 1999; 59: 5002-5011.
-
(1999)
Cancer Res
, vol.59
, pp. 5002-5011
-
-
Olumi, A.F.1
Grossfeld, G.D.2
Hayward, S.W.3
Carroll, P.R.4
Tlsty, T.D.5
Cunha, G.R.6
-
4
-
-
0036828120
-
Inhibition of transforming growth factor-β activity decreases angiogenesis in a human prostate cancer-reactive stroma xenograft model
-
Tuxhorn JA, McAlhany SJ, Yang F, Dang TD, Rowley DR. Inhibition of transforming growth factor-β activity decreases angiogenesis in a human prostate cancer-reactive stroma xenograft model. Cancer Res 2002; 62: 6021-6025.
-
(2002)
Cancer Res
, vol.62
, pp. 6021-6025
-
-
Tuxhorn, J.A.1
McAlhany, S.J.2
Yang, F.3
Dang, T.D.4
Rowley, D.R.5
-
5
-
-
0036718369
-
Reactive stroma in human prostate cancer
-
Tuxhorn JA, Ayala GE, Smith MJ, Smith VC, Dang TD, Rowley DR. Reactive stroma in human prostate cancer. Clin Cancer Res 2002; 8: 2912-2923.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 2912-2923
-
-
Tuxhorn, J.A.1
Ayala, G.E.2
Smith, M.J.3
Smith, V.C.4
Dang, T.D.5
Rowley, D.R.6
-
6
-
-
58149334773
-
A stromarelated gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer
-
Farmer P, Bonnefoi H, Anderle P, Cameron D, Wirapati P, Becette V et al. A stromarelated gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer. Nat Med 2009; 15: 68-74.
-
(2009)
Nat Med
, vol.15
, pp. 68-74
-
-
Farmer, P.1
Bonnefoi, H.2
Anderle, P.3
Cameron, D.4
Wirapati, P.5
Becette, V.6
-
7
-
-
84857924444
-
The prognostic value of tumour-stroma ratio in triple-negative breast cancer
-
Moorman AM, Vink R, Heijmans HJ, van der Palen J, Kouwenhoven EA. The prognostic value of tumour-stroma ratio in triple-negative breast cancer. Eur J Surg Oncol 2012; 38: 307-313.
-
(2012)
Eur J Surg Oncol
, vol.38
, pp. 307-313
-
-
Moorman, A.M.1
Vink, R.2
Heijmans, H.J.3
Van Der Palen, J.4
Kouwenhoven, E.A.5
-
8
-
-
67650248525
-
Presence of a high amount of stroma and downregulation of SMAD4 predict for worse survival for stage I-II colon cancer patients
-
Mesker WE, Liefers G-J, Junggeburt JMC, van Pelt GW, Alberici P, Kuppen PJK et al. Presence of a high amount of stroma and downregulation of SMAD4 predict for worse survival for stage I-II colon cancer patients. Cell Oncol 2009; 31: 169-178.
-
(2009)
Cell Oncol
, vol.31
, pp. 169-178
-
-
Mesker, W.E.1
Liefers, G.-J.2
Junggeburt, J.M.C.3
Van Pelt, G.W.4
Alberici, P.5
Kuppen, P.J.K.6
-
9
-
-
34250863385
-
Transforming growth factor-β signaling in prostate stromal cells supports prostate carcinoma growth by up-regulating stromal genes related to tissue remodeling
-
Verona EV, Elkahloun AG, Yang J, Bandyopadhyay A, Yeh I-T, Sun L-Z. Transforming growth factor-β signaling in prostate stromal cells supports prostate carcinoma growth by up-regulating stromal genes related to tissue remodeling. Cancer Res 2007; 67: 5737-5746.
-
(2007)
Cancer Res
, vol.67
, pp. 5737-5746
-
-
Verona, E.V.1
Elkahloun, A.G.2
Yang, J.3
Bandyopadhyay, A.4
Yeh, I.-T.5
Sun, L.-Z.6
-
10
-
-
25444491206
-
Gene expression profiling reveals novel TGFbeta targets in adult lung fibroblasts
-
Renzoni E, Abraham D, Howat S, Shi-Wen X, Sestini P, Bou-Gharios G et al. Gene expression profiling reveals novel TGFbeta targets in adult lung fibroblasts. Respir Res 2004; 5: 24.
-
(2004)
Respir Res
, vol.5
, pp. 24
-
-
Renzoni, E.1
Abraham, D.2
Howat, S.3
Shi-Wen, X.4
Sestini, P.5
Bou-Gharios, G.6
-
11
-
-
84859073207
-
Recent developments in myofibroblast biology: Paradigms for connective tissue remodeling
-
Hinz B, Phan SH, Thannickal VJ, Prunotto M, Desmoulière A, Varga J et al. Recent developments in myofibroblast biology: paradigms for connective tissue remodeling. Am J Path 2012; 180: 1340-1355.
-
(2012)
Am J Path
, vol.180
, pp. 1340-1355
-
-
Hinz, B.1
Phan, S.H.2
Thannickal, V.J.3
Prunotto, M.4
Desmoulière, A.5
Varga, J.6
-
12
-
-
78649958307
-
Cancer exosomes activate fibroblast to myofibroblast differentiation in a TGFβ dependent manner
-
Webber J, Steadman R, Tabi Z, Mason MD, Clayton A. Cancer exosomes activate fibroblast to myofibroblast differentiation in a TGFβ dependent manner. Cancer Res 2010; 70: 9621-9630.
-
(2010)
Cancer Res
, vol.70
, pp. 9621-9630
-
-
Webber, J.1
Steadman, R.2
Tabi, Z.3
Mason, M.D.4
Clayton, A.5
-
13
-
-
84871451335
-
Gastric cancer exosomes trigger differentiation of umbilical cord derived mesenchymal stem cells to carcinoma-associated fibroblasts through TGF-β/Smad pathway
-
Gu J, Qian H, Shen L, Zhang X, Zhu W, Huang L et al. Gastric cancer exosomes trigger differentiation of umbilical cord derived mesenchymal stem cells to carcinoma-associated fibroblasts through TGF-β/Smad pathway. PLoS One 2012; 7: e52465.
-
(2012)
PLoS One
, vol.7
, pp. e52465
-
-
Gu, J.1
Qian, H.2
Shen, L.3
Zhang, X.4
Zhu, W.5
Huang, L.6
-
14
-
-
0029989258
-
B Lymphocytes secrete antigen-presenting vesicles
-
Raposo G, Nijman HW, Stoorvogel W, Leijendekker R, Harding CV, Melief CJM et al. B Lymphocytes secrete antigen-presenting vesicles. J Exp Med 1996; 183: 1161-1172.
-
(1996)
J Exp Med
, vol.183
, pp. 1161-1172
-
-
Raposo, G.1
Nijman, H.W.2
Stoorvogel, W.3
Leijendekker, R.4
Harding, C.V.5
Melief, C.J.M.6
-
15
-
-
40049112564
-
Ceramide triggers budding of exosome vesicles into multivesicular endosomes
-
Trajkovic K, Hsu C, Chiantia S, Rajendran L, Wenzel D, Wieland F et al. Ceramide triggers budding of exosome vesicles into multivesicular endosomes. Science 2008; 319: 1244-1247.
-
(2008)
Science
, vol.319
, pp. 1244-1247
-
-
Trajkovic, K.1
Hsu, C.2
Chiantia, S.3
Rajendran, L.4
Wenzel, D.5
Wieland, F.6
-
17
-
-
34249302620
-
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
-
Valadi H, Ekström K, Bossios A, Sjöstrand M, Lee JJ, Lötvall JO. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol 2007; 9: 654-659.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 654-659
-
-
Valadi, H.1
Ekström, K.2
Bossios, A.3
Sjöstrand, M.4
Lee, J.J.5
Lötvall, J.O.6
-
18
-
-
68849129712
-
Membrane vesicles as conveyors of immune responses
-
Thery C, Ostrowski M, Segura E. Membrane vesicles as conveyors of immune responses. Nat Rev Immunol 2009; 9: 581-593.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 581-593
-
-
Thery, C.1
Ostrowski, M.2
Segura, E.3
-
19
-
-
77958553947
-
Surface-bound TGF-b on effusion-derived exosomes participates in maintenance of number and suppressive function of regulatory T-Cells in malignant effusions
-
Junji W, Hideya O, Hiroyuki S, Akio Y, Shuntaro N, Takashi M et al. Surface-bound TGF-b on effusion-derived exosomes participates in maintenance of number and suppressive function of regulatory T-Cells in malignant effusions. Anticancer Res 2010; 30: 3747-3757.
-
(2010)
Anticancer Res
, vol.30
, pp. 3747-3757
-
-
Junji, W.1
Hideya, O.2
Hiroyuki, S.3
Akio, Y.4
Shuntaro, N.5
Takashi, M.6
-
20
-
-
47249144117
-
Human tumorderived exosomes down-modulate NKG2D expression
-
Clayton A, Mitchell JP, Court J, Linnane S, Mason MD, Tabi Z. Human tumorderived exosomes down-modulate NKG2D expression. J Immunol 2008; 180: 7249-7258.
-
(2008)
J Immunol
, vol.180
, pp. 7249-7258
-
-
Clayton, A.1
Mitchell, J.P.2
Court, J.3
Linnane, S.4
Mason, M.D.5
Tabi, Z.6
-
21
-
-
34547686145
-
Human tumour-derived exosomes selectively impair lymphocyte responses to Interleukin-2
-
Clayton A, Mitchell JP, Court J, Mason MD, Tabi Z. Human tumour-derived exosomes selectively impair lymphocyte responses to Interleukin-2. Cancer Res 2007; 67: 7458-7466.
-
(2007)
Cancer Res
, vol.67
, pp. 7458-7466
-
-
Clayton, A.1
Mitchell, J.P.2
Court, J.3
Mason, M.D.4
Tabi, Z.5
-
22
-
-
79957879331
-
Exosomes released by melanoma cells prepare sentinel lymph nodes for tumor metastasis
-
Hood JL, San RS, Wickline SA. Exosomes released by melanoma cells prepare sentinel lymph nodes for tumor metastasis. Cancer Res 2011; 71: 3792-3801.
-
(2011)
Cancer Res
, vol.71
, pp. 3792-3801
-
-
Hood, J.L.1
San, R.S.2
Wickline, S.A.3
-
23
-
-
84862007577
-
Melanoma exosomes educate bone marrow progenitor cells toward a prometastatic phenotype through MET
-
Peinado H, Aleckovic M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G et al. Melanoma exosomes educate bone marrow progenitor cells toward a prometastatic phenotype through MET. Nat Med 2012; 18: 883-891.
-
(2012)
Nat Med
, vol.18
, pp. 883-891
-
-
Peinado, H.1
Aleckovic, M.2
Lavotshkin, S.3
Matei, I.4
Costa-Silva, B.5
Moreno-Bueno, G.6
-
24
-
-
77957708340
-
New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes
-
Sheldon H, Heikamp E, Turley H, Dragovic R, Thomas P, Oon CE et al. New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes. Blood 2010; 116: 2385-2394.
-
(2010)
Blood
, vol.116
, pp. 2385-2394
-
-
Sheldon, H.1
Heikamp, E.2
Turley, H.3
Dragovic, R.4
Thomas, P.5
Oon, C.E.6
-
25
-
-
33746886963
-
Systemic induction of the angiogenesis switch by the tetraspanin D6.1A/CO-029
-
Gesierich S, Berezovskiy I, Ryschich E, Zoller M. Systemic induction of the angiogenesis switch by the tetraspanin D6.1A/CO-029. Cancer Res 2006; 66: 7083-7094.
-
(2006)
Cancer Res
, vol.66
, pp. 7083-7094
-
-
Gesierich, S.1
Berezovskiy, I.2
Ryschich, E.3
Zoller, M.4
-
26
-
-
70350681050
-
Paracrine induction of endothelium by tumor exosomes
-
Hood JL, Pan H, Lanza GM, Wickline SA. Paracrine induction of endothelium by tumor exosomes. Lab Invest 2009; 89: 1317-1328.
-
(2009)
Lab Invest
, vol.89
, pp. 1317-1328
-
-
Hood, J.L.1
Pan, H.2
Lanza, G.M.3
Wickline, S.A.4
-
27
-
-
76749106591
-
Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosomeinduced endothelial cell activation
-
Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M et al. Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosomeinduced endothelial cell activation. Cancer Res 2010; 70: 1668-1678.
-
(2010)
Cancer Res
, vol.70
, pp. 1668-1678
-
-
Nazarenko, I.1
Rana, S.2
Baumann, A.3
McAlear, J.4
Hellwig, A.5
Trendelenburg, M.6
-
28
-
-
0023214021
-
Colonic pericrypt sheath cells: Characterisation of cell type with new monoclonal antibody
-
Richman PI, Tilly R, Jass JR, Bodmer WF. Colonic pericrypt sheath cells: characterisation of cell type with new monoclonal antibody. J Clin Pathol 1987; 40: 593-600.
-
(1987)
J Clin Pathol
, vol.40
, pp. 593-600
-
-
Richman, P.I.1
Tilly, R.2
Jass, J.R.3
Bodmer, W.F.4
-
29
-
-
81855212548
-
Uses of the in vitro endothelial-fibroblast organotypic co-culture assay in angiogenesis research
-
Hetheridge C, Mavria G, Mellor H. Uses of the in vitro endothelial-fibroblast organotypic co-culture assay in angiogenesis research. Biochem Soc Trans 2011; 39: 1597-1600.
-
(2011)
Biochem Soc Trans
, vol.39
, pp. 1597-1600
-
-
Hetheridge, C.1
Mavria, G.2
Mellor, H.3
-
30
-
-
0024580166
-
Multiple distinct membrane heparan sulfate proteoglycans in human lung fibroblasts
-
Lories V, Cassiman JJ, Van den Berghe H, David G. Multiple distinct membrane heparan sulfate proteoglycans in human lung fibroblasts. J Biol Chem 1989; 264: 7009-7016.
-
(1989)
J Biol Chem
, vol.264
, pp. 7009-7016
-
-
Lories, V.1
Cassiman, J.J.2
Van Den Berghe, H.3
David, G.4
-
31
-
-
77950254591
-
Complementary actions of inhibitors of angiopoietin-2 and VEGF on tumor angiogenesis and growth
-
Hashizume H, Falcon BL, Kuroda T, Baluk P, Coxon A, Yu D et al. Complementary actions of inhibitors of angiopoietin-2 and VEGF on tumor angiogenesis and growth. Cancer Res 2010; 70: 2213-2223.
-
(2010)
Cancer Res
, vol.70
, pp. 2213-2223
-
-
Hashizume, H.1
Falcon, B.L.2
Kuroda, T.3
Baluk, P.4
Coxon, A.5
Yu, D.6
-
32
-
-
77957044257
-
Improvement in disability after alemtuzumab treatment of multiple sclerosis is associated with neuroprotective autoimmunity
-
Jones JL, Anderson JM, Phuah CL, Fox EJ, Selmaj K, Margolin D et al. Improvement in disability after alemtuzumab treatment of multiple sclerosis is associated with neuroprotective autoimmunity. Brain 2010; 133(Pt 8): 2232-2247.
-
(2010)
Brain
, vol.133
, pp. 2232-2247
-
-
Jones, J.L.1
Anderson, J.M.2
Phuah, C.L.3
Fox, E.J.4
Selmaj, K.5
Margolin, D.6
-
33
-
-
0037967300
-
Plasminogen activator inhibitor-1 in tumor growth, angiogenesis and vascular remodeling
-
Stefansson S, McMahon GA, Petitclerc E, Lawrence DA. Plasminogen activator inhibitor-1 in tumor growth, angiogenesis and vascular remodeling. Curr Pharm Des 2003; 9: 1545-1564.
-
(2003)
Curr Pharm Des
, vol.9
, pp. 1545-1564
-
-
Stefansson, S.1
McMahon, G.A.2
Petitclerc, E.3
Lawrence, D.A.4
-
34
-
-
13944276728
-
Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancer
-
Ma PC, Jagadeeswaran R, Jagadeesh S, Tretiakova MS, Nallasura V, Fox EA et al. Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancer. Cancer Res 2005; 65: 1479-1488.
-
(2005)
Cancer Res
, vol.65
, pp. 1479-1488
-
-
Ma, P.C.1
Jagadeeswaran, R.2
Jagadeesh, S.3
Tretiakova, M.S.4
Nallasura, V.5
Fox, E.A.6
-
35
-
-
79953136097
-
Rab27a and Rab27b control different steps of the exosome secretion pathway
-
Ostrowski M, Carmo NB, Krumeich S, Fanget I, Raposo G, Savina A et al. Rab27a and Rab27b control different steps of the exosome secretion pathway. Nat Cell Biol 2010; 12: 19-30.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 19-30
-
-
Ostrowski, M.1
Carmo, N.B.2
Krumeich, S.3
Fanget, I.4
Raposo, G.5
Savina, A.6
-
36
-
-
0026750213
-
Receptors for the TGF-beta family
-
Massague J. Receptors for the TGF-beta family. Cell 1992; 69: 1067-1070.
-
(1992)
Cell
, vol.69
, pp. 1067-1070
-
-
Massague, J.1
-
37
-
-
43249123632
-
Increased exosome production from tumour cell cultures using the Integra CELLine Culture System
-
Mitchell JP, Court J, Mason MD, Tabi Z, Clayton A. Increased exosome production from tumour cell cultures using the Integra CELLine Culture System. J Immunol Methods 2008 ; 335: 98-105.
-
(2008)
J Immunol Methods
, vol.335
, pp. 98-105
-
-
Mitchell, J.P.1
Court, J.2
Mason, M.D.3
Tabi, Z.4
Clayton, A.5
-
38
-
-
0037114287
-
Production and characterization of clinical grade exosomes derived from dendritic cells
-
Lamparski H, Metha-Damani A, Yao J, Patel S, Hsu D, Ruegg C et al. Production and characterization of clinical grade exosomes derived from dendritic cells. J Immunol Methods 2002; 270: 211-226.
-
(2002)
J Immunol Methods
, vol.270
, pp. 211-226
-
-
Lamparski, H.1
Metha-Damani, A.2
Yao, J.3
Patel, S.4
Hsu, D.5
Ruegg, C.6
-
39
-
-
77953161017
-
Proteomic analysis of bladder cancer exosomes
-
Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J et al. Proteomic analysis of bladder cancer exosomes. Mol Cell Proteomics 2010; 6: 1324-1338.
-
(2010)
Mol Cell Proteomics
, vol.6
, pp. 1324-1338
-
-
Welton, J.L.1
Khanna, S.2
Giles, P.J.3
Brennan, P.4
Brewis, I.A.5
Staffurth, J.6
-
40
-
-
79960516623
-
Cancer exosomes express CD39 and CD73, which suppress T cells through adenosine production
-
Clayton A, Al-Taei S, Webber J, Mason MD, Tabi Z. Cancer exosomes express CD39 and CD73, which suppress T cells through adenosine production. J Immunol 2011; 187: 676-683.
-
(2011)
J Immunol
, vol.187
, pp. 676-683
-
-
Clayton, A.1
Al-Taei, S.2
Webber, J.3
Mason, M.D.4
Tabi, Z.5
-
41
-
-
0042121256
-
Mfold web server for nucleic acid folding and hybridization prediction
-
Zuker M. Mfold web server for nucleic acid folding and hybridization prediction. Nucleic Acids Res 2003; 31: 3406-3415.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 3406-3415
-
-
Zuker, M.1
-
42
-
-
34447321375
-
Com-1/p8 acts as a putative tumour suppressor in prostate cancer
-
Jiang WG, Davies G, Martin TA, Kynaston H, Mason MD, Fodstad O. Com-1/p8 acts as a putative tumour suppressor in prostate cancer. Int J Mol Med 2006; 18: 981-986.
-
(2006)
Int J Mol Med
, vol.18
, pp. 981-986
-
-
Jiang, W.G.1
Davies, G.2
Martin, T.A.3
Kynaston, H.4
Mason, M.D.5
Fodstad, O.6
-
43
-
-
66149119371
-
Hyaluronan orchestrates transforming growth factor-beta1-dependent maintenance of myofibroblast phenotype
-
Webber J, Meran S, Steadman R, Phillips A. Hyaluronan orchestrates transforming growth factor-beta1-dependent maintenance of myofibroblast phenotype. J Biol Chem 2009; 284: 9083-9092.
-
(2009)
J Biol Chem
, vol.284
, pp. 9083-9092
-
-
Webber, J.1
Meran, S.2
Steadman, R.3
Phillips, A.4
|