Interleukin-10 gene transfer into insulin-producing β cells protects against diabetes in non-obese diabetic mice

Molecular Medicine Reports

Volumn 12, Issue 3, 2015, Pages 3881-3889

  Xu, Aijing ^a   Zhu, Wei ^b   Li, Tang ^c   Li, Xiuzhen ^a   Cheng, Jing ^a   Li, Cuiling ^a   Yi, Peng ^a   Liu, Li ^a  

^a GUANGZHOU MEDICAL UNIVERSITY   (China)

^b GUANGDONG MEDICAL UNIVERSITY   (China)

^c QINGDAO UNIVERSITY   (China)

Author keywords

Apoptosis; Caspase; Interlukin 10; Non obese diabetic mice

Indexed keywords

ADENOVIRUS VECTOR; CASPASE 3; DNA NUCLEOTIDYLEXOTRANSFERASE; DRUG CARRIER; ENHANCED GREEN FLUORESCENT PROTEIN; FAS ANTIGEN; GAMMA INTERFERON; GLUCOSE; GREEN FLUORESCENT PROTEIN; INTERLEUKIN 10; RECOMBINANT INTERLEUKIN 10; TRANSCRIPTION FACTOR FOXP3; IL10 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNITY; CD4+ CD25+ T LYMPHOCYTE; CELL ACTIVITY; CLINICAL ASSESSMENT; CLINICAL EVALUATION; COMPARATIVE STUDY; CONTROLLED STUDY; DIABETES MELLITUS; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; ENZYME MECHANISM; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; GENE TRANSFER; GLUCOSE BLOOD LEVEL; IMMUNOHISTOCHEMISTRY; IMMUNOMODULATION; INCIDENCE; INSULITIS; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; PANCREAS ISLET BETA CELL; REGULATORY T LYMPHOCYTE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLEEN CELL; TH1 TH2 BALANCE; TUNEL ASSAY; ADENOVIRIDAE; ANIMAL; BIOSYNTHESIS; DIABETES MELLITUS, TYPE 1; GENE THERAPY; GENETIC TRANSDUCTION; GENETICS; IMMUNOLOGY; IMPAIRED GLUCOSE TOLERANCE; METABOLISM; PANCREAS; PATHOLOGY; PROTECTION;

ADENOVIRIDAE; MUS;

ADENOVIRIDAE; ANIMALS; APOPTOSIS; DIABETES MELLITUS, TYPE 1; FEMALE; GENE EXPRESSION; GENETIC THERAPY; INSULIN-SECRETING CELLS; INTERLEUKIN-10; MICE, INBRED NOD; PANCREAS; PREDIABETIC STATE; PROTECTIVE FACTORS; T-LYMPHOCYTES, REGULATORY; TRANSDUCTION, GENETIC;

EID: 84935482155     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.3809     Document Type: Article

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