Long term exposure to polyphenols of artichoke (cynara scolymus L.) Exerts induction of senescence driven growth arrest in the MDA-MB231 human breast cancer cell line

Oxidative Medicine and Cellular Longevity

Volumn 2015, Issue , 2015, Pages

  Mileo, Anna Maria ^a   Di Venere, Donato ^b   Abbruzzese, Claudia ^a   Miccadei, Stefania ^a  

^a REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

^b INSTITUTE OF SCIENCES OF FOOD PRODUCTION   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLATION; AMINO ACIDS; CELL CULTURE; CELL DEATH; CELL GROWTH; CYTOLOGY; DISEASES; GROWTH KINETICS; POLYPHENOLIC COMPOUNDS;

ANTIPROLIFERATIVE EFFECT; BREAST CANCER CELLS; CANCER CHEMOPREVENTION; EPIGENETIC ALTERATIONS; HUMAN BREAST CANCER CELLS; MOLECULAR MECHANISM; REACTIVE OXYGEN SPECIES; TUMOUR SUPPRESSOR GENES;

CELLS;

ACETYLCYSTEINE; BETA GALACTOSIDASE; CASPASE; CYCLIN DEPENDENT KINASE INHIBITOR 2A; LYSINE; POLYPHENOL; REACTIVE OXYGEN METABOLITE; CYCLIN DEPENDENT KINASE INHIBITOR 1A;

ACETYLATION; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICHOKE; ARTICLE; BREAST CANCER CELL LINE; CANCER CELL; CANCER INHIBITION; CELL AGING; CELL VIABILITY; CYTOTOXICITY; DNA METHYLATION; EPIGENETICS; LONG TERM EXPOSURE; METHYLATION; P16 INK4A GENE; P21 CIP1 WAF1 GENE; PROTEIN EXPRESSION; TUMOR SUPPRESSOR GENE; UPREGULATION; BREAST TUMOR; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECTS; FEMALE; HCT 116 CELL LINE; HUMAN; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

CYNARA SCOLYMUS;

ACETYLCYSTEINE; BREAST NEOPLASMS; CELL AGING; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYNARA SCOLYMUS; FEMALE; HCT116 CELLS; HUMANS; POLYPHENOLS; REACTIVE OXYGEN SPECIES;

EID: 84934899880     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.1155/2015/363827     Document Type: Article

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