메뉴 건너뛰기




Volumn 11, Issue 1, 2014, Pages

Cancer prevention trial of a synergistic mixture of green tea concentrate plus capsicum (capsol-t) in a random population of subjects ages 40-84

Author keywords

Cancer; Capsol t ; Curative prevention ; Early detection; Early intervention; Green tea concentrate; Oncoblot tissue of origin cancer test; Prevention trial

Indexed keywords

ANTINEOPLASTIC AGENT; CAPSOL T; ENOX2 PROTEIN; TUMOR PROTEIN; UNCLASSIFIED DRUG;

EID: 84903716032     PISSN: 15426416     EISSN: 15590275     Source Type: Journal    
DOI: 10.1186/1559-0275-11-2     Document Type: Article
Times cited : (5)

References (43)
  • 4
    • 77955497101 scopus 로고    scopus 로고
    • Current and emerging concepts in tumor metastasis
    • Coghlin C, Murray GI: Current and emerging concepts in tumor metastasis. J Pathol 2010, 222(1):1-35.
    • (2010) J Pathol , vol.222 , Issue.1 , pp. 1-35
    • Coghlin, C.1    Murray, G.I.2
  • 5
    • 84903722090 scopus 로고    scopus 로고
    • Early detection: An opportunity for cancer prevention through early intervention
    • Edited by Georgakilas AG. Rijeka: In Tech
    • Morré DJ, Morré DM: Early detection: An opportunity for cancer prevention through early intervention. In Cancer Prevention. Edited by Georgakilas AG. Rijeka: In Tech; 2012:389-402.
    • (2012) Cancer Prevention , pp. 389-402
    • Morré, D.J.1    Morré, D.M.2
  • 6
    • 0037133540 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a tumor-associated, growth-related, and time-keeping hydroquinone (NADH) oxidase (tNOX) of the HeLa cell surface
    • DOI 10.1021/bi012041t
    • Chueh PJ, Kim C, Cho N, Morré DM, Morré DJ: Molecular cloning and characterization of a tumor-associated, growth-related, and timekeeping hydroquinone (NADH) oxidase (tNOX) of the HeLa cell surface. Biochemistry 2002, 41(11):3732-3741. (Pubitemid 34224687)
    • (2002) Biochemistry , vol.41 , Issue.11 , pp. 3732-3741
    • Chueh, P.-J.1    Kim, C.2    Cho, N.3    Morre, D.M.4    Morre, D.J.5
  • 8
    • 0036218624 scopus 로고    scopus 로고
    • Monoclonal antibody to a cancer-specific and drug-responsive hydroquinone (NADH) oxidase from the sera of cancer patients
    • DOI 10.1007/s00262-001-0262-2
    • Cho N, Chueh PJ, Kim C, Caldwell S, Morré DM, Morré DJ: Monoclonal antibody to a cancer- specific and drug-responsive hydroquinone (NADH) oxidase from the sera of cancer patients. Cancer Immunol Immunother 2002, 51(3):121-129. (Pubitemid 34298107)
    • (2002) Cancer Immunology, Immunotherapy , vol.51 , Issue.3 , pp. 121-129
    • Cho, N.1    Chueh, P.-J.2    Kim, C.3    Caldwell, S.4    Morre, D.M.5    Morre, J.D.6
  • 9
    • 0043198154 scopus 로고    scopus 로고
    • Cell surface NADH oxidases (ECTO-NOX proteins) with roles in cancer, cellular time-keeping, growth, aging and neurodegenerative diseases
    • DOI 10.1080/1071576031000083107
    • Morré DJ, Morré DM: Cell surface NADH oxidases (ECTO-NOX proteins) with roles in cancer, cellular time-keeping, growth, aging and neurodegenerative diseases. Free Radic Res 2003, 37(18):795-808. (Pubitemid 36939596)
    • (2003) Free Radical Research , vol.37 , Issue.8 , pp. 795-808
    • Morre, D.J.1    Morre, D.M.2
  • 10
    • 35648944675 scopus 로고    scopus 로고
    • Alternative splicing as the basis for specific localization of tNOX, a unique hydroquinone (NADH) oxidase, to the cancer cell surface
    • DOI 10.1021/bi700973k
    • Tang X, Tian Z, Chueh PJ, Chen S, Morré DM, Morré DJ: Alternative splicing as the basis for specific localization of tNOX, a unique hydroquionone (NADH) oxidase, to the cancer cell surface. Biochemistry 2007, 46(43):12337-12346. (Pubitemid 350022388)
    • (2007) Biochemistry , vol.46 , Issue.43 , pp. 12337-12346
    • Tang, X.1    Tian, Z.2    Chueh, P.-J.3    Chen, S.4    Morre, D.M.5    Morre, D.J.6
  • 11
    • 40449094075 scopus 로고    scopus 로고
    • Antisense experiments demonstrate an exon 4 minus splice variant mRNA as the basis for expression of tNOX, a cancer-specific cell surface protein
    • DOI 10.3727/000000007783630006
    • Tang X, Morré DJ, Morré DM: Antisense experiments demonstrate an exon 4 minus splice variant mRNA as the basis for expression of tNOX, a cancer-specific cell surface protein. Oncol Res 2008, 16(12):557-567. (Pubitemid 351344778)
    • (2007) Oncology Research , vol.16 , Issue.12 , pp. 557-567
    • Tang, X.1    Morre, D.J.2    Morre, D.M.3
  • 12
    • 33748951935 scopus 로고    scopus 로고
    • Spotlight on tNOX: A tumor-selective target for cancer therapies
    • Davies SL, Bozzo J: Spotlight on tNOX: A tumor-selective target for cancer therapies. Drug News Prospect 2006, 19(4):223-225.
    • Drug News Prospect 2006 , vol.19 , Issue.4 , pp. 223-225
    • Davies, S.L.1    Bozzo, J.2
  • 13
    • 79956073475 scopus 로고    scopus 로고
    • Trans-plasma membrane electron transport in mammals: Functional significance in health and disease
    • Del Principe D, Avigalo L, Savini I, Catani MV: Trans-plasma membrane electron transport in mammals: functional significance in health and disease. Antioxid Redox Signal 2011, 14(11):2289-2318.
    • (2011) Antioxid Redox Signal , vol.14 , Issue.11 , pp. 2289-2318
    • Del Principe, D.1    Avigalo, L.2    Savini, I.3    Catani, M.V.4
  • 14
    • 70349115265 scopus 로고    scopus 로고
    • Cancer site-specific isoforms of ENOX2 (tNOX), a cancer-specific cell surface oxidase
    • Hostetler B, Weston N, Kim C, Morré DM, Morré DJ: Cancer site-specific isoforms of ENOX2 (tNOX), a cancer-specific cell surface oxidase. Clin Proteomics 2009, 5:46-51.
    • (2009) Clin Proteomics , vol.5 , pp. 46-51
    • Hostetler, B.1    Weston, N.2    Kim, C.3    Morré, D.M.4    Morré, D.J.5
  • 17
    • 33748949820 scopus 로고    scopus 로고
    • Transgenic mouse line overexpressing the cancer-specific tNOX protein has an enhanced growth and acquired drug-response phenotype
    • DOI 10.1016/j.jnutbio.2005.12.006, PII S0955286305003232
    • Yagiz K, Morré DJ, Morré DM: Transgenic mouse expressing the cancerspecific tNOX protein has an enhanced growth and acquired drugresponse phenotype. J Nutr Biochem 2006, 17(11):750-759. (Pubitemid 44557048)
    • (2006) Journal of Nutritional Biochemistry , vol.17 , Issue.11 , pp. 750-759
    • Yagiz, K.1    Morre, D.J.2    Morre, D.M.3
  • 19
    • 34547795968 scopus 로고    scopus 로고
    • New York. (Fig. 11.1, Courtesy of WK Hong compiled from SEER Cancer Statistics Review). New York: Garland Science)
    • Weinberg RA: The Biology of Cancer, Garland Science, New York. (Fig. 11.1, Courtesy of WK Hong compiled from SEER Cancer Statistics Review). New York: Garland Science; 1996:796.
    • (1996) The Biology of Cancer Garland Science , pp. 796
    • Weinberg, R.A.1
  • 20
    • 0036728057 scopus 로고    scopus 로고
    • A mRNA molecule encoding truncated excitatory amino acid carrier 1 (EAAC1) protein (EAAC2) is transcribed from an independent promoter but not an alternative splicing event
    • Jin XP, Peng JB, Pang H, Zhu YN, Fei J, Gup LH: A mRNA molecule encoding truncated excitatory amino acid carrier 1 (EAAC1) protein (EAAC2) is transcribed from an independent promoter but not as an alternative splicing event. Cell Res 2002, 12(3-4):257-262. (Pubitemid 135707528)
    • (2002) Cell Research , vol.12 , Issue.3-4 , pp. 257-262
    • Jin, X.P.1    Peng, J.B.2    Huang, F.3    Zhu, Y.N.4    Fei, J.5    Guo, L.H.6
  • 22
    • 0034308086 scopus 로고    scopus 로고
    • Preferential inhibition by (-)-epigallocatechin-3-gallate of the cell surface NADH oxidase and growth of transformed cells in culture
    • Morré DJ, Bridge A, Wu LY, Morré DM: Preferential inhibition by (-)-epigallocatechin-3-gallate of the cell surface NADH oxidase and growth of transformed cells in culture. Biochem Pharmacol 2000, 60(7):937-946.
    • (2000) Biochem Pharmacol , vol.60 , Issue.7 , pp. 937-946
    • Morré, D.J.1    Bridge, A.2    Wu, L.Y.3    Morré, D.M.4
  • 23
    • 0028925916 scopus 로고
    • Capsaicin inhibits preferentially the NADH oxidase and growth of transformed cells in culture
    • Morré DJ, Chueh P-J, Morré DM: Capsaicin inhibits preferentially the NADH oxidase and growth of transformed cells in culture. Proc Natl Acad Sci USA 1995, 92(6):1831-1835.
    • (1995) Proc Natl Acad Sci USA , vol.92 , Issue.6 , pp. 1831-1835
    • Morré, D.J.1    Chueh, P.-J.2    Morré, D.M.3
  • 24
    • 0037407436 scopus 로고    scopus 로고
    • Tea catechin synergies in inhibition of cancer cell proliferation and of a cancer specific cell surface oxidase (ECTO-NOX)
    • DOI 10.1034/j.1600-0773.2003.920506.x
    • Morré DJ, Morré DM, Sun H, Cooper R, Chang J, Janle EM: Tea catechin synergies in inhibition of cancer cell proliferation and of a cancerspecific cell surface oxidase (ECTO-NOX). Pharmacol Toxicol 2003, 92(5):234-241. (Pubitemid 36513219)
    • (2003) Pharmacology and Toxicology , vol.92 , Issue.5 , pp. 234-241
    • Morre, D.J.1    Morre, D.M.2    Sun, H.3    Cooper, R.4    Chang, J.5    Janle, E.M.6
  • 25
    • 0042666892 scopus 로고    scopus 로고
    • Synergistic Capsicum-tea mixtures with anticancer activity
    • DOI 10.1211/0022357021521
    • Morré DJ, Morré DM: Synergistic Capsicum-tea mixtures with anticancer activity. J Pharm Pharm 2003, 55(7):987-994. (Pubitemid 36916689)
    • (2003) Journal of Pharmacy and Pharmacology , vol.55 , Issue.7 , pp. 987-994
    • Morre, D.J.1    Morre, D.M.2
  • 26
    • 58149168556 scopus 로고    scopus 로고
    • Pharmacokinetics of green tea catechins in extract and sustained-release preparations
    • Janle E, Morré DM, Morré DJ, Zhou Q, Chang H, Zhu Y: Pharmacokinetics of green tea catechins in extract and sustained-release preparations. J Dietary Suppl 2008, 5(3):248-263.
    • (2008) J Dietary Suppl , vol.5 , Issue.3 , pp. 248-263
    • Janle, E.1    Morré, D.M.2    Morré, D.J.3    Zhou, Q.4    Chang, H.5    Zhu, Y.6
  • 27
    • 0032730946 scopus 로고    scopus 로고
    • Two stages of cancer prevention with green tea
    • DOI 10.1007/s004320050321
    • Fujiki H: Two stages of cancer prevention with green tea. J Cancer Res Clin Oncol 1999, 125(11):589-597. (Pubitemid 29502339)
    • (1999) Journal of Cancer Research and Clinical Oncology , vol.125 , Issue.11 , pp. 589-597
    • Fujiki, H.1
  • 28
    • 0034494832 scopus 로고    scopus 로고
    • Preventive effects of drinking green tea on cancer and cardiovascular disease: Epidemiological evidence for multiple targeting prevention
    • Nakachi K, Matsuyama S, Miyake S, Sugaruma M, Imai K: Preventive effects of drinking green tea on cancer and cardiovascular disease: epidemiological evidence for multiple targeting prevention. Biofactors 2000, 13(1-4):49-54. (Pubitemid 32107344)
    • (2000) BioFactors , vol.13 , Issue.1-4 , pp. 49-54
    • Nakachi, K.1    Matsuyama, S.2    Miyake, S.3    Suganuma, M.4    Imai, K.5
  • 29
    • 0029356361 scopus 로고
    • Absorption of (-)-epigallocatcechin gallate into the circulation system of rats
    • Unno T, Takeo T: Absorption of (-)-epigallocatcechin gallate into the circulation system of rats. Biosci Biotechnol Biochem 1995, 59(8):1558-1559.
    • (1995) Biosci Biotechnol Biochem , vol.59 , Issue.8 , pp. 1558-1559
    • Unno, T.1    Takeo, T.2
  • 30
    • 0034083836 scopus 로고    scopus 로고
    • Oral absorption and bioavailability of tea catechins
    • DOI 10.1055/s-2000-8599
    • Zhu M, Chen Y, Li RC: Oral absorption and bioavailability of tea catechins. Planta Med 2000, 66(5):444-447. (Pubitemid 30413506)
    • (2000) Planta Medica , vol.66 , Issue.5 , pp. 444-447
    • Zhu, M.1    Chen, Y.2    Li, R.C.3
  • 32
    • 0031441473 scopus 로고    scopus 로고
    • Absorption and distribution of tea catechin, (-)-epigallocatechin-3- gallate, in the rat
    • Nakagawa KMT: Absorption and distribution of tea catechin, (-)-epigallocatechin-3-gallate, in the rat. J Nutr Sci Vitaminol 1997, 43(6):679-684.
    • (1997) J Nutr Sci Vitaminol , vol.43 , Issue.6 , pp. 679-684
    • Nakagawa, K.M.T.1
  • 33
    • 0030817716 scopus 로고    scopus 로고
    • Inhibition of carcinogenesis by tea
    • Yang CS: Inhibition of carcinogenesis by tea. Nature 1997, 389(6647):134-135.
    • (1997) Nature , vol.389 , Issue.6647 , pp. 134-135
    • Yang, C.S.1
  • 34
    • 0031310905 scopus 로고    scopus 로고
    • Dose-dependent Incorporation of Tea Catechins, (-)-Epigallocatechin-3- gallate and (-)-Epigallocatechin, into Human Plasma
    • Nakagawa K, Okuda S, Miyazawa T: Dose-dependent incorporation of tea catechins, (-)- epigallocatechin-3-gallate and (-)-epigallocatechin, into human plasma. Biosci Biotechnol Biochem 1997, 61(12):1981-1985. (Pubitemid 127473054)
    • (1997) Bioscience, Biotechnology and Biochemistry , vol.61 , Issue.12 , pp. 1981-1985
    • Nakagawa, K.1    Okuda, S.2    Miyazawa, T.3
  • 35
    • 0033000095 scopus 로고    scopus 로고
    • Plasma and lipoprotein levels of tea catechins following repeated tea consumption
    • van het Hof KH, Wiseman SA, Chang CS, Tijburg BM: Plasma and lipoprotein levels of tea catechins following repeated tea consumption. Proc Soc Exp Biol Med 1999, 220(4):203-209.
    • (1999) Proc Soc Exp Biol Med , vol.220 , Issue.4 , pp. 203-209
    • Van Het Hof, K.H.1    Wiseman, S.A.2    Chang, C.S.3    Tijburg, B.M.4
  • 37
    • 13444304185 scopus 로고    scopus 로고
    • Tnox is both necessary and sufficient as a cellular target for the anticancer actions of capsaicin and the green tea catechin (-)-epigallocatechin- 3-gallate
    • Chueh PJ, Wu L-Y, Morré DM, Morré DJ: TNOX is both necessary and sufficient as a cellular target for the anticancer actions of capsaicin and the green tea catechin (-)-epigallocatechin-3-gallate. Biofactors 2004, 20(4):235-249.
    • (2004) Biofactors , vol.20 , Issue.4 , pp. 235-249
    • Chueh, P.J.1    Wu, L.-Y.2    Morré, D.M.3    Morré, D.J.4
  • 38
  • 39
    • 33645237951 scopus 로고    scopus 로고
    • Safety studies on epigallo catechin gallate (EGCg) preparations Part 1: Genotoxicity
    • Isbrucker RA, Bausch J, Edwards JA, Wolz E: Safety studies on epigallocatechin gallate (EGCg) preparations. Part 1: genotoxicity. Food Chem Toxicol 2006, 44(5):626-635.
    • (2006) Food Chem Toxicol , vol.44 , Issue.5 , pp. 626-635
    • Isbrucker, R.A.1    Bausch, J.2    Edwards, J.A.3    Wolz, E.4
  • 40
    • 33645224473 scopus 로고    scopus 로고
    • Safety studies on epigall ocatechin gallate (EGCg) preparations Part 2: Dermal, acute and short-term toxicity studies
    • Isbrucker RA, Edwards JA, Wolz E, Davidovich A, Bausch J: Safety studies on epigallocatechin gallate (EGCg) preparations. Part 2: dermal, acute and short-term toxicity studies. Food Chem Toxicol 2006, 44(5):636-650.
    • (2006) Food Chem Toxicol , vol.44 , Issue.5 , pp. 636-650
    • Isbrucker, R.A.1    Edwards, J.A.2    Wolz, E.3    Davidovich, A.4    Bausch, J.5
  • 41
    • 33645211032 scopus 로고    scopus 로고
    • Safety studies on epigall ocatechin gallate (EGCg) preparations Part 3: Teratogenicity and reproductive toxicity studies in rats
    • Isbrucker RA, Edwards JA, Wolz E, Davidovich A, Bausch J: Safety studies on epigallocatechin gallate (EGCg) preparations. Part 3: Teratogenicity and reproductive toxicity studies in rats. Food Chem Toxicol 2006, 44(5):651-661.
    • (2006) Food Chem Toxicol , vol.44 , Issue.5 , pp. 651-661
    • Isbrucker, R.A.1    Edwards, J.A.2    Wolz, E.3    Davidovich, A.4    Bausch, J.5
  • 42
    • 84860099378 scopus 로고    scopus 로고
    • National Center for Complementary and Alternative Medicine: Botanical Fact Sheet, Green Tea, Bethesda: National Institues of Health
    • National Center for Complementary and Alternative Medicine: Botanical Fact Sheet, Green Tea, Office of Dietary Supplements. Bethesda: National Institues of Health; 2012:2.
    • (2012) Office of Dietary Supplements , pp. 2
  • 43
    • 77955493271 scopus 로고    scopus 로고
    • Reciprocal relationship between cytosolic NADH and ENOX2 inhibition triggers sphing olipid-induced apoptosis in hela cells
    • De Luca T, Morré DM, Morré DJ: Reciprocal relationship between cytosolic NADH and ENOX2 inhibition triggers sphingolipid-induced apoptosis in HeLa cells. J Cell Biochem 2010, 110(6):1504-1511.
    • (2010) J Cell Biochem , vol.110 , Issue.6 , pp. 1504-1511
    • De Luca, T.1    Morré, D.M.2    Morré, D.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.