Bisdemethoxycurcumin suppresses MCF-7 cells proliferation by inducing ROS accumulation and modulating senescence-related pathways

Pharmacological Reports

Volumn 65, Issue 3, 2013, Pages 700-709

  Li, Ying Bo ^a,b   Gao, Jian Li ^c,d   Zhong, Zhang Feng ^a   Hoi, Pui Man ^a   Lee, Simon Ming Yuen ^a   Wang, Yi Tao ^a  

^a University of Macau   (Macao)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^c UNIVERSITY OF CHICAGO MEDICAL CENTER   (United States)

^d ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

Author keywords

Bisdemethoxycurcumin (BDMC); Breast cancer; Reactive oxidative species (ROS); Rhizoma Curcumae Longae

Indexed keywords

DIDEMETHOXYCURCUMIN; PROTEIN P16; PROTEIN P21; PROTEIN P53; REACTIVE OXYGEN METABOLITE; RETINOBLASTOMA PROTEIN;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CELL PROLIFERATION; CELL STRAIN MCF 7; CELL VIABILITY; COLONY FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOSIS INHIBITION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ACETYLCYSTEINE; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; CELL AGING; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CURCUMIN; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYCLIN-DEPENDENT KINASE INHIBITOR P21; HUMANS; MCF-7 CELLS; MEMBRANE POTENTIAL, MITOCHONDRIAL; NITROGEN OXIDES; REACTIVE OXYGEN SPECIES; RETINOBLASTOMA PROTEIN; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84884486085     PISSN: 22995684     EISSN: 22995684     Source Type: Journal    
DOI: 10.1016/S1734-1140(13)71048-X     Document Type: Article

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