2-Thiouracil deprived of thiocarbonyl function preferentially base pairs with guanine rather than adenine in RNA and DNA duplexes

Nucleic Acids Research

Volumn 43, Issue 5, 2015, Pages 2499-2512

  Sochacka, Elzbieta ^a   Szczepanowski, Roman H ^b   Cypryk, Marek ^c   Sobczak, Milena ^c   Janicka, Magdalena ^c   Kraszewska, Karina ^c   Bartos, Paulina ^a   Chwialkowska, Anna ^c   Nawrot, Barbara ^c  

^a LODZ UNIVERSITY OF TECHNOLOGY   (Poland)

^b INTERNATIONAL INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Poland)

^c CENTRE OF MOLECULAR AND MACROMOLECULAR STUDIES   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

4 PYRIMIDINONE; ADENINE; DOUBLE STRANDED DNA; FUNCTIONAL GROUP; GUANINE; OLIGOMER; RNA; RNA DUPLEX; THIOURACIL; TRANSFER RNA; UNCLASSIFIED DRUG; URACIL; URIDINE; 2-THIOURIDINE; DNA; HETERODUPLEX; THIOURIDINE;

ARTICLE; BASE PAIR MODEL; BASE PAIRING; CIRCULAR DICHROISM; CODON; CONTROLLED STUDY; DESULFURIZATION; DIFFERENTIAL SCANNING CALORIMETRY; DISCRETE FOURIER TRANSFORM; ENTHALPY; FOURIER TRANSFORMATION; HYDROGEN BOND; IN VITRO STUDY; MATHEMATICAL MODEL; MOLECULAR BIOLOGY; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MECHANICS; NUCLEIC ACID BASE SUBSTITUTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROCESS OPTIMIZATION; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; THERMODYNAMIC STABILITY; THERMODYNAMICS; THIOCARBONYL FUNCTION; ANALOGS AND DERIVATIVES; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DNA DENATURATION; GENETICS;

ADENINE; BASE PAIRING; CIRCULAR DICHROISM; DNA; GUANINE; MODELS, CHEMICAL; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; NUCLEIC ACID DENATURATION; NUCLEIC ACID HETERODUPLEXES; RNA; THERMODYNAMICS; THIOURACIL; THIOURIDINE;

EID: 84934839931     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkv109     Document Type: Article

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