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Volumn 14, Issue 6, 2015, Pages 791-803

Co-treatment with anthocyanins and vitamin C ameliorates ethanol-induced neurodegeneration via modulation of GABAB receptor signaling in the adult rat brain

Author keywords

Anthocyanins; Apoptotic signaling pathway; Neuroprotection; Protein kinase AcAMP response element binding protein pathway; aminobutyric acid B1 receptor

Indexed keywords

4 AMINOBUTYRIC ACID B RECEPTOR; ANTHOCYANIN; ASCORBIC ACID; CASPASE 3; CASPASE 9; CYANIDIN 3 GLUCOSIDE; CYTOCHROME C; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN BAX; PROTEIN BCL 2; ALCOHOL; ANTIOXIDANT; CENTRAL DEPRESSANT AGENT; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN;

EID: 84934767515     PISSN: 18715273     EISSN: 19963181     Source Type: Journal    
DOI: 10.2174/1871527314666150225142919     Document Type: Article
Times cited : (22)

References (69)
  • 1
    • 0035751002 scopus 로고    scopus 로고
    • Mechanisms of alcohol-induced damage to the developing nervous system
    • Goodlett CR, Horn KH. Mechanisms of alcohol-induced damage to the developing nervous system. Alcohol Res Health 2001; 25: 175-84.
    • (2001) Alcohol Res Health , vol.25 , pp. 175-184
    • Goodlett, C.R.1    Horn, K.H.2
  • 2
    • 20444468898 scopus 로고    scopus 로고
    • Alcohol teratogenesis: Mechanisms of damage and strategies for intervention
    • Goodlett CR, Horn KH, Zhou FC. Alcohol teratogenesis: Mechanisms of damage and strategies for intervention. Exp Biol Med 2005; 230: 394-406.
    • (2005) Exp Biol Med , vol.230 , pp. 394-406
    • Goodlett, C.R.1    Horn, K.H.2    Zhou, F.C.3
  • 3
    • 0036123834 scopus 로고    scopus 로고
    • Binge ethanol exposure in adult rats causes necrotic cell death
    • Obernier JA, Bouldin TW, Crews FT. Binge ethanol exposure in adult rats causes necrotic cell death. Alcohol Clin Exp Res 2002; 26: 547-57.
    • (2002) Alcohol Clin Exp Res , vol.26 , pp. 547-557
    • Obernier, J.A.1    Bouldin, T.W.2    Crews, F.T.3
  • 4
    • 8744309183 scopus 로고    scopus 로고
    • Chronic ethanol treatment enhances inflammatory mediators and cell death in the brain and in astrocytes
    • Valles SL, Blanco AM, Pascual M, Guerri C. Chronic ethanol treatment enhances inflammatory mediators and cell death in the brain and in astrocytes. Brain Pathol 2004; 14: 365-71.
    • (2004) Brain Pathol , vol.14 , pp. 365-371
    • Valles, S.L.1    Blanco, A.M.2    Pascual, M.3    Guerri, C.4
  • 6
    • 60749114856 scopus 로고    scopus 로고
    • Linking binge alcohol-induced neurodamage to brain edema and potential aquaporin-4 upregulation: Evidence in rat organotypic brain slice cultures and in vivo
    • Sripathirathan K, Brown J, Neafsey EJ, Collins MA. Linking binge alcohol-induced neurodamage to brain edema and potential aquaporin-4 upregulation: evidence in rat organotypic brain slice cultures and in vivo. J Neurotrauma 2009; 26: 261-73.
    • (2009) J Neurotrauma , vol.26 , pp. 261-273
    • Sripathirathan, K.1    Brown, J.2    Neafsey, E.J.3    Collins, M.A.4
  • 7
    • 77952909330 scopus 로고    scopus 로고
    • B receptor and PKA-α expression in prenatal rat brain
    • B receptor and PKA-α expression in prenatal rat brain. Synapse 2010; 64: 467-77.
    • (2010) Synapse , vol.64 , pp. 467-477
    • Naseer, M.I.1    Lee, H.I.2    Kim, M.O.3
  • 8
    • 70350593689 scopus 로고    scopus 로고
    • Vitamin-C protect ethanol induced apoptotic neurodegeneration in post natal rat brain
    • Naseer MI, Ullah N, Ullah I, et al. Vitamin-C protect ethanol induced apoptotic neurodegeneration in post natal rat brain. Pak J Med Sci 2009; 25: 718-22.
    • (2009) Pak J Med Sci , vol.25 , pp. 718-722
    • Naseer, M.I.1    Ullah, N.2    Ullah, I.3
  • 9
    • 84907000415 scopus 로고    scopus 로고
    • Differential sensitivity of prefrontal cortex and hippocampus to alcohol-induced toxicity
    • Flower A-K, Thompson J, Chen L, et al. Differential sensitivity of prefrontal cortex and hippocampus to alcohol-induced toxicity. PLoS ONE 2014; 9: e10694.
    • (2014) PLoS ONE , vol.9
    • Flower, A.-K.1    Thompson, J.2    Chen, L.3
  • 10
    • 0031688235 scopus 로고    scopus 로고
    • Chronic ethanol consumption: From neuroadaptation to neurodegeneration
    • Fadda F, Rossetti ZL. Chronic ethanol consumption: from neuroadaptation to neurodegeneration. Prog Neurobiol 1998; 56: 385-431.
    • (1998) Prog Neurobiol , vol.56 , pp. 385-431
    • Fadda, F.1    Rossetti, Z.L.2
  • 11
    • 77955047048 scopus 로고    scopus 로고
    • B receptors: Physiological functions and mechanisms of diversity
    • B receptors: physiological functions and mechanisms of diversity. Adv Pharmacol 2010; 58: 231-55.
    • (2010) Adv Pharmacol , vol.58 , pp. 231-255
    • Pinard, A.1    Seddik, R.2    Bettler, B.3
  • 12
    • 0024464218 scopus 로고
    • GABA as an inhibitory neurotransmitter in human cerebral cortex
    • McCormick DA. GABA as an inhibitory neurotransmitter in human cerebral cortex. J Neurophysiol 1989; 62: 1018-27.
    • (1989) J Neurophysiol , vol.62 , pp. 1018-1027
    • McCormick, D.A.1
  • 14
    • 27444434493 scopus 로고    scopus 로고
    • B receptor expression in cortex and hippocampus of the adult rat brain
    • B receptor expression in cortex and hippocampus of the adult rat brain. Brain Res 2005; 1061: 27-35.
    • (2005) Brain Res , vol.1061 , pp. 27-35
    • Li, S.P.1    Park, M.S.2    Jin, G.Z.3
  • 16
    • 0030985420 scopus 로고    scopus 로고
    • Effects of chronic ethanol exposure on GABA receptors and GABA, receptor modulation of 3H-GABA release in the hippocampus
    • Peris J, Eppler B, Hu M, et al. Effects of chronic ethanol exposure on GABA receptors and GABA, receptor modulation of 3H-GABA release in the hippocampus. Alchol Clin Exp Res 1997; 21: 1047-52.
    • (1997) Alchol Clin Exp Res , vol.21 , pp. 1047-1052
    • Peris, J.1    Eppler, B.2    Hu, M.3
  • 17
    • 0034656653 scopus 로고    scopus 로고
    • High ethanol consumption and low sensitivity to ethanol-induced sedation in protein kinase A-mutant mice
    • Thiele TE, Willis B, Stadler J, Reynolds JG, Bernstein IL, McKnight GS. High ethanol consumption and low sensitivity to ethanol-induced sedation in protein kinase A-mutant mice. J Neurosci 2000; 20: 75-85.
    • (2000) J Neurosci , vol.20 , pp. 75-85
    • Thiele, T.E.1    Willis, B.2    Stadler, J.3    Reynolds, J.G.4    Bernstein, I.L.5    McKnight, G.S.6
  • 18
    • 0031014559 scopus 로고    scopus 로고
    • Cellular and molecular neuroscience of alcoholism
    • Diamond I, Gordon AS. Cellular and molecular neuroscience of alcoholism. Physiol Rev 1997; 77: 1-20.
    • (1997) Physiol Rev , vol.77 , pp. 1-20
    • Diamond, I.1    Gordon, A.S.2
  • 19
    • 34848846591 scopus 로고    scopus 로고
    • Anti-obesity and hypolipidemic effects of black soybean anthocyanins
    • Kwon SH, Ahn IS, Kim SO, et al. Anti-obesity and hypolipidemic effects of black soybean anthocyanins. J Med Food 2007; 10: 552-6.
    • (2007) J Med Food , vol.10 , pp. 552-556
    • Kwon, S.H.1    Ahn, I.S.2    Kim, S.O.3
  • 21
    • 33746611085 scopus 로고    scopus 로고
    • Carotenoids and other pigments as natural colorants
    • Mortensen A. Carotenoids and other pigments as natural colorants. Pure Appl Chem 2006; 78: 1477-91.
    • (2006) Pure Appl Chem , vol.78 , pp. 1477-1491
    • Mortensen, A.1
  • 22
    • 0141724271 scopus 로고
    • Anticonvulsant effect of anthocyanins and antioxidants
    • Drenska D, Banttutova I, Oveharov R. Anticonvulsant effect of anthocyanins and antioxidants. Fomatsiya 1989; 30: 33-40.
    • (1989) Fomatsiya , vol.30 , pp. 33-40
    • Drenska, D.1    Banttutova, I.2    Oveharov, R.3
  • 23
    • 0032986801 scopus 로고    scopus 로고
    • Antioxidant and antiinflammatory activities of anthocyanins and their aglycon, cyanidin, from tart cherries
    • Wang H, Nair MG, Strasburg GM, et al. Antioxidant and antiinflammatory activities of anthocyanins and their aglycon, cyanidin, from tart cherries. J Nat Prod 1999; 62: 294-6.
    • (1999) J Nat Prod , vol.62 , pp. 294-296
    • Wang, H.1    Nair, M.G.2    Strasburg, G.M.3
  • 24
    • 81255188830 scopus 로고    scopus 로고
    • Neuroprotective effects of anthocyanins on apoptosis induced by mitochondrial oxidative stress
    • Kelsey N, Hulick W, Winter A, Ross E, Linseman D. Neuroprotective effects of anthocyanins on apoptosis induced by mitochondrial oxidative stress. Nutr Neurosci 2011; 14: 249-59.
    • (2011) Nutr Neurosci , vol.14 , pp. 249-259
    • Kelsey, N.1    Hulick, W.2    Winter, A.3    Ross, E.4    Linseman, D.5
  • 25
    • 34548010792 scopus 로고    scopus 로고
    • Neuroprotective effects of anthocyanins and their in vivo metabolites in SH-SY5Y cells
    • Tarozzia A, Morronia F, Hreliab S, et al. Neuroprotective effects of anthocyanins and their in vivo metabolites in SH-SY5Y cells. Neurosci Lett 2007; 424: 36-40.
    • (2007) Neurosci Lett , vol.424 , pp. 36-40
    • Tarozzia, A.1    Morronia, F.2    Hreliab, S.3
  • 26
    • 0001218860 scopus 로고
    • Ascorbate is an outstanding antioxidant in human blood plasma
    • Frei B, England L, Ames BN. Ascorbate is an outstanding antioxidant in human blood plasma. Proc Nat Acad Sci USA 1989; 86: 6377-81.
    • (1989) Proc Nat Acad Sci USA , vol.86 , pp. 6377-6381
    • Frei, B.1    England, L.2    Ames, B.N.3
  • 27
    • 34249782834 scopus 로고    scopus 로고
    • Evaluation of subchronic chlorpyrifos poisoning on hematological and serum biochemical changes in mice and protective effect of vitamin C
    • Ambali S, Akanbi D, Igbokwe N, Shittu M, Kawu M, Ayo J. Evaluation of subchronic chlorpyrifos poisoning on hematological and serum biochemical changes in mice and protective effect of vitamin C. J Toxicol Sci 2007; 32: 111-20.
    • (2007) J Toxicol Sci , vol.32 , pp. 111-120
    • Ambali, S.1    Akanbi, D.2    Igbokwe, N.3    Shittu, M.4    Kawu, M.5    Ayo, J.6
  • 28
    • 77949327875 scopus 로고    scopus 로고
    • Ameliorative effect of vitamin C on chronic chlorpyrifos-induced erythrocyte osmotic fragility in Wistar rats
    • El-Hossary GG, Mansour SM, Mohamed AS. Ameliorative effect of vitamin C on chronic chlorpyrifos-induced erythrocyte osmotic fragility in Wistar rats. J Appl Sci Res 2009; 5: 1218-22.
    • (2009) J Appl Sci Res , vol.5 , pp. 1218-1222
    • El-Hossary, G.G.1    Mansour, S.M.2    Mohamed, A.S.3
  • 29
    • 84886951607 scopus 로고    scopus 로고
    • Anthocyanins attenuate body weight gain via modulating neuropeptide Y and GABAB1 receptor in rat hypothalamus
    • Badshah H, Ullah I, Kim SE, Kim TH, Lee HY, Kim MO. Anthocyanins attenuate body weight gain via modulating neuropeptide Y and GABAB1 receptor in rat hypothalamus. Neuropeptides 2013; 47: 347-53.
    • (2013) Neuropeptides , vol.47 , pp. 347-353
    • Badshah, H.1    Ullah, I.2    Kim, S.E.3    Kim, T.H.4    Lee, H.Y.5    Kim, M.O.6
  • 30
    • 84880923702 scopus 로고    scopus 로고
    • B1receptors intracellular signaling in prenatal rat hippocampal neurons
    • B1receptors intracellular signaling in prenatal rat hippocampal neurons. Mol Neurobiol 2013; 48: 257-69.
    • (2013) Mol Neurobiol , vol.48 , pp. 257-269
    • Shah, S.A.1    Ullah, I.2    Lee, H.Y.3    Kim, M.O.4
  • 31
    • 0035543027 scopus 로고    scopus 로고
    • Isolation and determination of anthocyanins in seed coats of black soybean
    • Choung MG, Baek IY, Kang ST, et al. Isolation and determination of anthocyanins in seed coats of black soybean. J Agric Food Chem 2001; 49: 5848-51.
    • (2001) J Agric Food Chem , vol.49 , pp. 5848-5851
    • Choung, M.G.1    Baek, I.Y.2    Kang, S.T.3
  • 32
    • 84934271980 scopus 로고    scopus 로고
    • Novel osmotin attenuates glutamate-induced synaptic dysfunction and neurodegeneration via the JNK/PI3K/Akt pathway in postnatal rat brain
    • Shah SA, Lee HY, Bressan RA, Yun DJ, Kim MO. Novel osmotin attenuates glutamate-induced synaptic dysfunction and neurodegeneration via the JNK/PI3K/Akt pathway in postnatal rat brain. Cell Death Dis 2014; 5: 1026.
    • (2014) Cell Death Dis , vol.5
    • Shah, S.A.1    Lee, H.Y.2    Bressan, R.A.3    Yun, D.J.4    Kim, M.O.5
  • 33
    • 80053615952 scopus 로고    scopus 로고
    • Protective effect of pyruvate against ethanol-induced apoptotic neurodegeneration in the developing rat brain
    • Ullah N, Naseer MI, Ullah I, Lee HY, Koh PO, Kim MO. Protective effect of pyruvate against ethanol-induced apoptotic neurodegeneration in the developing rat brain. Neuropharmacology 2011, 61: 1248-55.
    • (2011) Neuropharmacology , vol.61 , pp. 1248-1255
    • Ullah, N.1    Naseer, M.I.2    Ullah, I.3    Lee, H.Y.4    Koh, P.O.5    Kim, M.O.6
  • 34
    • 84897396173 scopus 로고    scopus 로고
    • Neuroprotective effect of osmotin against ethanol-induced apoptotic neurodegeneration in the developing brain
    • Naseer MI, Ullah I, Narasimhan ML, et al. Neuroprotective effect of osmotin against ethanol-induced apoptotic neurodegeneration in the developing brain. Cell Death Dis 2014; 5: 1150.
    • (2014) Cell Death Dis , vol.5
    • Naseer, M.I.1    Ullah, I.2    Narasimhan, M.L.3
  • 35
    • 0031918223 scopus 로고    scopus 로고
    • Bcl-2 family: Regulators of cell death
    • Chao DT, Korsmeye SJ. Bcl-2 family: regulators of cell death. Annu Rev Immunol 1998; 16: 395-419.
    • (1998) Annu Rev Immunol , vol.16 , pp. 395-419
    • Chao, D.T.1    Korsmeye, S.J.2
  • 36
    • 0030715323 scopus 로고    scopus 로고
    • Cytochrome c and dATPdependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
    • Li P, Nijhawan D, Budihardjo I, et al. Cytochrome c and dATPdependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997; 91: 479-89.
    • (1997) Cell , vol.91 , pp. 479-489
    • Li, P.1    Nijhawan, D.2    Budihardjo, I.3
  • 37
    • 0037069451 scopus 로고    scopus 로고
    • Caspase activation and neuroprotection in caspase-3 deficient mice after in vivo cerebral ischemia and in vitro oxygen glucose deprivation
    • Le DA, Wu Y, Huang Z, et al. Caspase activation and neuroprotection in caspase-3 deficient mice after in vivo cerebral ischemia and in vitro oxygen glucose deprivation. Proc Natl Acad Sci 2002; 99: 15188-93.
    • (2002) Proc Natl Acad Sci , vol.99 , pp. 15188-15193
    • Le, D.A.1    Wu, Y.2    Huang, Z.3
  • 38
    • 1842509989 scopus 로고    scopus 로고
    • Caspase-3 and calpain activities after acute and repeated ethanol administration during the rat brain growth spurt
    • Carloni S, Mazzoni E, Balduini W. Caspase-3 and calpain activities after acute and repeated ethanol administration during the rat brain growth spurt. J Neurochem 2004; 89: 197-203.
    • (2004) J Neurochem , vol.89 , pp. 197-203
    • Carloni, S.1    Mazzoni, E.2    Balduini, W.3
  • 39
    • 0021997074 scopus 로고
    • Poly(ADP-ribose) in the cellular response to DNA damage
    • Berger NA. Poly(ADP-ribose) in the cellular response to DNA damage. Radiat Res 1985; 101: 4-15.
    • (1985) Radiat Res , vol.101 , pp. 4-15
    • Berger, N.A.1
  • 40
    • 84896701849 scopus 로고    scopus 로고
    • Reducing GABAergic inhibition restores cognitive functions in a mouse model of Down syndrome
    • Potier MC, Braudeau J, Dauphinot L, Delatour B. Reducing GABAergic inhibition restores cognitive functions in a mouse model of Down syndrome. CNS Neurol Disord Drug Targets 2014; 13: 8-15.
    • (2014) CNS Neurol Disord Drug Targets , vol.13 , pp. 8-15
    • Potier, M.C.1    Braudeau, J.2    Dauphinot, L.3    Delatour, B.4
  • 41
    • 34250663055 scopus 로고    scopus 로고
    • Ethanol's effect on intracellular signal pathways in prenatal rat cortical neurons is GABAB1 dependent
    • Lee HY, Li SP, Park MS, Bahk YK, Chung BC, Kim MO. Ethanol's effect on intracellular signal pathways in prenatal rat cortical neurons is GABAB1 dependent. Synapse 2007; 61: 622-8.
    • (2007) Synapse , vol.61 , pp. 622-628
    • Lee, H.Y.1    Li, S.P.2    Park, M.S.3    Bahk, Y.K.4    Chung, B.C.5    Kim, M.O.6
  • 42
    • 80051791713 scopus 로고    scopus 로고
    • Downregulation of CREB expression in Alzheimer's brain and in Aβ-treated rat hippocampal neurons
    • Pugazhenthi S, Wang M, Pham S, Sze CI, Eckman CB. Downregulation of CREB expression in Alzheimer's brain and in Aβ-treated rat hippocampal neurons. Mol Neurodegener 2011; 6: 60.
    • (2011) Mol Neurodegener , vol.6
    • Pugazhenthi, S.1    Wang, M.2    Pham, S.3    Sze, C.I.4    Eckman, C.B.5
  • 43
    • 0029870044 scopus 로고    scopus 로고
    • Neuronal degeneration in rat cerebrocortical and olfactory regions during subchronic "binge" intoxication with ethanol: Possible explanation for olfactory deficits in alcoholics
    • Collins MA, Corso TD, Neafsey EJ. Neuronal degeneration in rat cerebrocortical and olfactory regions during subchronic "binge" intoxication with ethanol: possible explanation for olfactory deficits in alcoholics. Alcohol Clin Exp Res 1996; 20: 284-92.
    • (1996) Alcohol Clin Exp Res , vol.20 , pp. 284-292
    • Collins, M.A.1    Corso, T.D.2    Neafsey, E.J.3
  • 44
    • 0033739075 scopus 로고    scopus 로고
    • Binge ethanol consumption causes differential brain damage in young adolescent rats compared with adult rats
    • Crews FT, Braun CJ, Hoplight B, Switzer RC, Knapp DJ. Binge ethanol consumption causes differential brain damage in young adolescent rats compared with adult rats. Alcohol Clin Exp Res 2000; 24: 1712-23.
    • (2000) Alcohol Clin Exp Res , vol.24 , pp. 1712-1723
    • Crews, F.T.1    Braun, C.J.2    Hoplight, B.3    Switzer, R.C.4    Knapp, D.J.5
  • 45
    • 84874381330 scopus 로고    scopus 로고
    • Determining the threshold for alcohol-induced brain damage: New evidence with gliosis markers
    • Hayes DM, Deeny MA, Shaner CA, Nixon K. Determining the threshold for alcohol-induced brain damage: New evidence with gliosis markers. Alcohol Clin Exp Res 2013; 37: 425-34.
    • (2013) Alcohol Clin Exp Res , vol.37 , pp. 425-434
    • Hayes, D.M.1    Deeny, M.A.2    Shaner, C.A.3    Nixon, K.4
  • 46
    • 0141893370 scopus 로고    scopus 로고
    • Ethanol-induced neuronal apoptosis in vivo requires BAX in the developing mouse brain
    • Young C, Klocke BJ, Tenkova T, et al. Ethanol-induced neuronal apoptosis in vivo requires BAX in the developing mouse brain. Cell Death Diff 2003; 10: 1148-55.
    • (2003) Cell Death Diff , vol.10 , pp. 1148-1155
    • Young, C.1    Klocke, B.J.2    Tenkova, T.3
  • 47
    • 0037069929 scopus 로고    scopus 로고
    • Chemotherapy: Targeting the mitochondrial cell death pathway
    • Debatin KM, Poncet D, Kroemer G. Chemotherapy: targeting the mitochondrial cell death pathway. Oncogene 2002; 21: 8786-803.
    • (2002) Oncogene , vol.21 , pp. 8786-8803
    • Debatin, K.M.1    Poncet, D.2    Kroemer, G.3
  • 48
    • 0026442071 scopus 로고
    • Ethanol toxicity and oxidative stress
    • Bondy SC. Ethanol toxicity and oxidative stress. Toxicol Lett 1992; 63: 231-41.
    • (1992) Toxicol Lett , vol.63 , pp. 231-241
    • Bondy, S.C.1
  • 49
    • 0031010080 scopus 로고    scopus 로고
    • Chronic ethanol increases N methyl-D-aspartate-stimulated nitric oxide formation but not receptor density in cultured cortical neurons
    • Chandler LJ, Sutton G, Norwood D, Sumners C, Crews FT. Chronic ethanol increases N methyl-D-aspartate-stimulated nitric oxide formation but not receptor density in cultured cortical neurons. Mol Pharmacol 1997; 51: 733-40.
    • (1997) Mol Pharmacol , vol.51 , pp. 733-740
    • Chandler, L.J.1    Sutton, G.2    Norwood, D.3    Sumners, C.4    Crews, F.T.5
  • 50
    • 0032847556 scopus 로고    scopus 로고
    • Ethanol stimulates the production of reactive oxygen species at mitochondrial complexes I and III
    • Bailey SM, Pietsch EC, Cunningham CC. Ethanol stimulates the production of reactive oxygen species at mitochondrial complexes I and III. Free Radic Biol Med 1999; 27: 891-900.
    • (1999) Free Radic Biol Med , vol.27 , pp. 891-900
    • Bailey, S.M.1    Pietsch, E.C.2    Cunningham, C.C.3
  • 51
    • 0000896315 scopus 로고    scopus 로고
    • Chronic ethanol consumption affects glutathione status in rat liver
    • Oh SI, Kim CI, Chun HL, Park SC: Chronic ethanol consumption affects glutathione status in rat liver. J Nutr 1997; 128: 758-63.
    • (1997) J Nutr , vol.128 , pp. 758-763
    • Oh, S.I.1    Kim, C.I.2    Chun, H.L.3    Park, S.C.4
  • 52
    • 0033580091 scopus 로고    scopus 로고
    • Grape polyphenols protect neurodegenerative changes induced by chronic ethanol administration
    • Sun GY, Xia J, Draczynska-Lusiak B, Simonyi A, Sun AY. Grape polyphenols protect neurodegenerative changes induced by chronic ethanol administration. Neuroreport 1999; 10: 93-96.
    • (1999) Neuroreport , vol.10 , pp. 93-96
    • Sun, G.Y.1    Xia, J.2    Draczynska-Lusiak, B.3    Simonyi, A.4    Sun, A.Y.5
  • 53
    • 0032102438 scopus 로고    scopus 로고
    • Dietary supplementation of grape polyphenols and chronic ethanol administration on LDL oxidation and platelet function in rats
    • Xia JM, Allenbrand B, Sun GY. Dietary supplementation of grape polyphenols and chronic ethanol administration on LDL oxidation and platelet function in rats. Life Sci 1998; 63: 383-90.
    • (1998) Life Sci , vol.63 , pp. 383-390
    • Xia, J.M.1    Allenbrand, B.2    Sun, G.Y.3
  • 54
    • 79957867318 scopus 로고    scopus 로고
    • Anthocyanins: Natural colorants with healthpromoting properties
    • He J, Giusti MM. Anthocyanins: Natural colorants with healthpromoting properties. Annu Rev Food Sci Technol 2009; 1: 163-87.
    • (2009) Annu Rev Food Sci Technol , vol.1 , pp. 163-187
    • He, J.1    Giusti, M.M.2
  • 55
    • 36749032228 scopus 로고    scopus 로고
    • Anthocyanins induce the activation of phase II enzymes through the antioxidant response element pathway against oxidative stress-induced apoptosis
    • Shih PH, Yeh CT, Yen GC. Anthocyanins induce the activation of phase II enzymes through the antioxidant response element pathway against oxidative stress-induced apoptosis. J Agric Food Chem 2007; 55: 9427-35.
    • (2007) J Agric Food Chem , vol.55 , pp. 9427-9435
    • Shih, P.H.1    Yeh, C.T.2    Yen, G.C.3
  • 56
    • 38349023171 scopus 로고    scopus 로고
    • Neuroprotective actions of vitamin C related to decreased lipid peroxidation and increased catalase activity in adult rats after pilocarpine-induced seizures
    • Santos LF, Freitas RL, Xavier SM, Saldanha GB, Freitas RM. Neuroprotective actions of vitamin C related to decreased lipid peroxidation and increased catalase activity in adult rats after pilocarpine-induced seizures. Pharmacol Biochem Behav 2008; 89: 1-5.
    • (2008) Pharmacol Biochem Behav , vol.89 , pp. 1-5
    • Santos, L.F.1    Freitas, R.L.2    Xavier, S.M.3    Saldanha, G.B.4    Freitas, R.M.5
  • 57
    • 84862986730 scopus 로고    scopus 로고
    • Vitamin C attenuates chronic chlorpyrifosinduced alteration of neurobehavioral parameters in wistar rats
    • Ambali SF, Ayo JO. Vitamin C attenuates chronic chlorpyrifosinduced alteration of neurobehavioral parameters in wistar rats. Toxicol Int 2012; 19: 144-52.
    • (2012) Toxicol Int , vol.19 , pp. 144-152
    • Ambali, S.F.1    Ayo, J.O.2
  • 58
    • 70349781407 scopus 로고    scopus 로고
    • Detection of apoptosis in the central nervous system
    • Lee Y, McKinnon PJ. Detection of apoptosis in the central nervous system. Methods Mol Biol 2009; 559: 273-82.
    • (2009) Methods Mol Biol , vol.559 , pp. 273-282
    • Lee, Y.1    McKinnon, P.J.2
  • 59
    • 0033985183 scopus 로고    scopus 로고
    • Apoptosis and the Nervous System
    • Sastry PS, Rao KS. Apoptosis and the Nervous System. J Neurochem 2000; 74: 1-20.
    • (2000) J Neurochem , vol.74 , pp. 1-20
    • Sastry, P.S.1    Rao, K.S.2
  • 60
    • 0034641936 scopus 로고    scopus 로고
    • Apoptosis in the nervous system
    • Yuan J, Yankner BA. Apoptosis in the nervous system. Nature 2000; 407: 802-9.
    • (2000) Nature , vol.407 , pp. 802-809
    • Yuan, J.1    Yankner, B.A.2
  • 62
    • 67649985942 scopus 로고    scopus 로고
    • Alcoholism: A systems approach from molecular physiology to addictive behavior
    • Spanagel R. Alcoholism: a systems approach from molecular physiology to addictive behavior. Physiol Rev 2009; 89: 649-705.
    • (2009) Physiol Rev , vol.89 , pp. 649-705
    • Spanagel, R.1
  • 63
    • 0036259020 scopus 로고    scopus 로고
    • Mammalian gammaaminobutyric acid(B) receptors: Structure and function
    • Bowery NG, Bettler B, Froestl W, et al. Mammalian gammaaminobutyric acid(B) receptors: structure and function. Pharmacol Rev 2002; 54: 247-64.
    • (2002) Pharmacol Rev , vol.54 , pp. 247-264
    • Bowery, N.G.1    Bettler, B.2    Froestl, W.3
  • 64
    • 0036479250 scopus 로고    scopus 로고
    • A single subunit (GB2) is required for G-protein activation by the heterodimeric GABA(B) receptor
    • Duthey B, Caudron S, Perroy J, et al. A single subunit (GB2) is required for G-protein activation by the heterodimeric GABA(B) receptor. J Biol Chem 2002; 277: 3236-41.
    • (2002) J Biol Chem , vol.277 , pp. 3236-3241
    • Duthey, B.1    Caudron, S.2    Perroy, J.3
  • 66
    • 0031981194 scopus 로고    scopus 로고
    • Chronic ethanol exposure impairs phosphorylation of CREB and CRE-binding activity in rat striatum
    • Yang X, Horn K, Wand GS. Chronic ethanol exposure impairs phosphorylation of CREB and CRE-binding activity in rat striatum. Alcohol Clin Exp Res 1998; 22: 382-90.
    • (1998) Alcohol Clin Exp Res , vol.22 , pp. 382-390
    • Yang, X.1    Horn, K.2    Wand, G.S.3
  • 67
    • 0031983182 scopus 로고    scopus 로고
    • Chronic ethanol administration decreases phosphorylation of cyclic AMP response element binding protein in granule cells of rat cerebellum
    • Yang X, Horn K, Baraban JM, Wand GS. Chronic ethanol administration decreases phosphorylation of cyclic AMP response element binding protein in granule cells of rat cerebellum. J Neurochem 1998; 70: 224-32.
    • (1998) J Neurochem , vol.70 , pp. 224-232
    • Yang, X.1    Horn, K.2    Baraban, J.M.3    Wand, G.S.4
  • 68
    • 42149113980 scopus 로고    scopus 로고
    • Protein kinase A-mediated CREB phosphorylation is an oxidant-induced survival pathway in alveolar type II cells
    • Barlow CA, Kitiphongspattana K, Siddiqui N, Roe MW, Mossman BT, Lounsbury KM. Protein kinase A-mediated CREB phosphorylation is an oxidant-induced survival pathway in alveolar type II cells. Apoptosis 2008; 13: 681-92.
    • (2008) Apoptosis , vol.13 , pp. 681-692
    • Barlow, C.A.1    Kitiphongspattana, K.2    Siddiqui, N.3    Roe, M.W.4    Mossman, B.T.5    Lounsbury, K.M.6
  • 69
    • 84855421010 scopus 로고    scopus 로고
    • The anthocyanin cyanidin-3-O-β-glucoside, a flavonoid, increases hepatic glutathione synthesis and protects hepatocytes against reactive oxygen species during hyperglycemia: Involvement of a cAMP-PKA-dependent signaling pathway
    • Zhu W, Jia Q, Wang Y, Zhang Y, Xia M. The anthocyanin cyanidin-3-O-β-glucoside, a flavonoid, increases hepatic glutathione synthesis and protects hepatocytes against reactive oxygen species during hyperglycemia: Involvement of a cAMP-PKA-dependent signaling pathway. Free Radic Biol Med 2012; 52: 314-27.
    • (2012) Free Radic Biol Med , vol.52 , pp. 314-327
    • Zhu, W.1    Jia, Q.2    Wang, Y.3    Zhang, Y.4    Xia, M.5


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