Novel osmotin attenuates glutamate-induced synaptic dysfunction and neurodegeneration via the JNK/PI3K/Akt pathway in postnatal rat brain

Cell Death and Disease

Volumn 5, Issue , 2014, Pages

  Shah, S A ^a   Lee, H Y ^a   Bressan, R A ^b   Yun, D J ^a   Kim, M O ^a  

^a Gyeongsang National University   (South Korea)

^b PURDUE UNIVERSITY   (United States)

Author keywords

adiponectin; excitotoxicity; glutamate; neurodegeneration; osmotin

Indexed keywords

ADIPONECTIN; CASPASE 3; CASPASE 7; GLUTAMATE RECEPTOR; GLUTAMIC ACID; NEUROPROTECTIVE AGENT; OSMOTIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P53; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; VEGETABLE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; OSMOTIN PROTEIN, NICOTIANA TABACUM;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CORTEX; BRAIN FUNCTION; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; DNA DAMAGE; DNA FRAGMENTATION; EXCITOTOXICITY; GLUTAMATE INDUCED EXCITOTOXICITY; HIPPOCAMPUS; IMMUNOFLUORESCENCE TEST; INTRACELLULAR SIGNALING; NERVE DEGENERATION; NEUROPROTECTION; NICOTIANA TABACUM; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SPRAGUE DAWLEY RAT; WESTERN BLOTTING; ANIMAL; BRAIN; DRUG EFFECT; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; METABOLISM; NERVE CELL PLASTICITY; PATHOPHYSIOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; SYNAPSE;

ANIMALS; BRAIN; GLUTAMIC ACID; HIPPOCAMPUS; HUMANS; MAP KINASE KINASE 4; NERVE DEGENERATION; NEURONAL PLASTICITY; NEUROPROTECTIVE AGENTS; PHOSPHATIDYLINOSITOL 3-KINASES; PLANT PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SYNAPSES;

EID: 84934271980     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2013.538     Document Type: Article

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