Differential sensitivity of prefrontal cortex and hippocampus to alcohol-induced toxicity

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Fowler, Anna Kate ^a   Thompson, Jeremy ^a   Chen, Lixia ^a   Dagda, Marisela ^a   Dertien, Janet ^a   Dossou, Katina Sylvestre S ^b   Moaddel, Ruin ^b   Bergeson, Susan E ^a   Kruman, Inna I ^a  

^a TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); ALCOHOL; BIOLOGICAL MARKER; HOMOCYSTEINE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MICROTUBULE ASSOCIATED PROTEIN; MTAP2 PROTEIN, MOUSE;

ALCOHOL INTOXICATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARBON METABOLISM; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; EXECUTIVE FUNCTION; GENOMIC INSTABILITY; HIPPOCAMPUS; MALE; MOUSE; NERVE CELL NECROSIS; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PREFRONTAL CORTEX; PROTEIN EXPRESSION; ACUTE DISEASE; ALCOHOLISM; ANIMAL; ANTIBODY SPECIFICITY; APOPTOSIS; C57BL MOUSE; CHRONIC DISEASE; DEFICIENCY; DRUG EFFECTS; GENE EXPRESSION; GENETICS; KNOCKOUT MOUSE; METABOLISM; NERVE CELL; PATHOLOGY; STEREOTACTIC PROCEDURE;

MUS;

ACUTE DISEASE; ALCOHOLISM; ANIMALS; APOPTOSIS; BIOMARKERS; CHRONIC DISEASE; DNA DAMAGE; DNA REPAIR; ETHANOL; GENE EXPRESSION; HIPPOCAMPUS; HOMOCYSTEINE; MALE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROTUBULE-ASSOCIATED PROTEINS; NEURONS; ORGAN SPECIFICITY; OXIDATIVE STRESS; PREFRONTAL CORTEX; STEREOTAXIC TECHNIQUES;

EID: 84907000415     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0106945     Document Type: Article

References (57)

1. Spanagel R (2009) Alcoholism: a systems approach from molecular physiology to addictive behavior. Physiological Reviews 89: 649-705
2. Harper C (2009) The neuropathology of alcohol-related brain damage. Alcohol Alcohol 44: 136-140
3. Luhar RB, Sawyer KS, Gravitz Z, Ruiz SM, Oscar-Berman M (2013) Brain volumes and neuropsychological performance are related to current smoking and alcoholism history. Neuropsychiatr Dis Treat 9: 1767-1784
4. Hashimoto E, Riederer PF, Hesselbrock VM, Hesselbrock MN, Mann K, et al. (2013) Consensus paper of the WFSBP task force on biological markers: biological markers for alcoholism. World J Biol Psychiatry 14: 549-564
5. Pau CW, Lee TM, Chan SF (2002) The impact of heroin on frontal executive functions. Arch Clin Neuropsychol 17: 663-670
6. Crews FT, Boettiger CA (2009) Impulsivity, frontal lobes and risk for addiction. Pharmacology, Biochemistry and Behavior 93: 237-247
7. Mathur P, Guo S (2011) Differences of Acute versus Chronic Ethanol Exposure on Anxiety-Like Behavioral Responses in Zebrafish. Behav Brain Res 219: 234-239
8. Cunha-Oliveira T, Rego AC, Oliveira CR (2008) Cellular and molecular mechanisms involved in the neurotoxicity of opioid and psychostimulant drugs. Brain Res. Rev 5 8: 192-208
9. Lindahl T (1993) Review Instability and decay of the primary structure of DNA. Nature 362: 709-715
10. Jacintho JD, Kovacic P (2003) Neurotransmission and neurotoxicity by nitric oxide, cathecholamines, and glutamate: unifying themes of reactive oxygen species and electron transfer. Curr Med Chem 10: 2693-2703
11. Ramalingam M, Kim SJ (2012) Reactive oxygen/nitrogen species and their functional correlations in neurodegenerative diseases. J Neural Transm 119: 891-910
12. Choi DH, Cristovao AC, Guhathakurta S, Lee J, Joh TH, et al. (2012) NADPH Oxidase 1-Mediated Oxidative Stress Leads to Dopamine Neuron Death in Parkinson's Disease. Antioxid. Redox Signal 16: 1033-1045
13. Singh NP, Lai H, Khan A (1995) Ethanol-induced single-strand DNA breaks in rat brain cells. Mutat Res 345: 191-196
14. Fowler A-K, Hewetson A, Agraval R, Dagda M, Dagda R, et al. (2012) The role of genomic instability in neurotoxicity of chronic alcohol abuse. J Biol Chem 287: 43533-43542
15. Bhupanapadu Sunkesula SR, Swain U, Babu PP (2008) Cell death is associated with reduced base excision repair during chronic alcohol administration in adult rat brain. Neurochem Res 33: 1117-1128
16. Cravo ML, Camilo ME (2000) Hyperhomocysteinemia in chronic alcoholism: relations to folic acid and vitamins B(6) and B(12) status. Nutrition 16: 296-302
17. Bleich S, Degner D, Javaheripour K, Kurth C, Kornhuber J (2000) Homocysteine and alcoholism. J Neural Transm Suppl 60: 187-196
18. Kruman II, Henderson GI, Bergeson SE (2012) DNA damage and neurotoxicity of chronic alcohol abuse. Exper Biol Med 237: 740-747
19. Fowler AK, Kruman II (2014) Impaired One Carbon Metabolism and DNA methylation in Alcohol Toxicity. J Neurochem. Feb [Epub ahead of print]
20. Sieber OM, Heinimann K, Tomlinson IP (2003) Genomic instability-the engine of tumorigenesis? Nat Rev Cancer 3: 701-708
21. Ventura I, Russo MT, De Luca G, Bignami M (2010) Oxidized purine nucleotides, genome instability and neurodegeneration. Mutat Res 703: 59-65
22. Marinkovic K, Rickenbacher E, Azma S, Artsy E (2012) Acute alcohol intoxication impairs top-down regulation of Stroop incongruity as revealed by blood oxygen level-dependent functional magnetic resonance imaging. Hum Brain Mapp. 33 : 319-333
23. Bjork JM, Gilman JM (2014) The effects of acute alcohol administration on the human brain: Insights from neuroimaging. Neuropharmacology 84: 101e110
24. Schulte T, Oberlin BG, Kareken DA, Marinkovic K, Muller-Oehring EM, et al. (2012) How Acute and Chronic Alcohol Consumption Affects Brain Networks: Insights from Multimodal Neuroimaging. Alcohol Clin Exp Res 36: 2017-2027
25. Koob GF, Volkow ND (2010) Neurocircuitry of addiction. Neuropsychopharmacology 35: 217-238
26. Bechara A, Damasio AR, Damasio H, Anderson SW (1994) Insensitivity to future consequences following damage to human prefrontal cortex. Cognition 50: 7-15
27. Berlin HA, Rolls ET, Kischka U (2004) Impulsivity, time perception, emotion and reinforcement sensitivity in patients with orbitofrontal cortex lesions. Brain 127: 1108-1126
28. Rudebeck PH, Walton ME, Smyth AN, Bannerman DM, Rushworth MF (2006) Separate neural pathways process different decision costs. Nat Neurosci 9: 1161-1168
29. Bechara A, Dolan S, Denburg N, Hindes A, Anderson SW, et al. (2001) Decision-making deficits, linked to a dysfunctional ventromedial prefrontal cortex, revealed in alcohol and stimulant abusers. Neuropsychologia 39: 376-389
30. Bechara A, Dolan S, Hindes A (2002) Decision-making and addiction (part II): myopia for the future or hypersensitivity to reward? Neuropsychologia 40: 1690-1705
31. Bechara A, Damasio H (2002) Decision-making and addiction (part I): impaired activation of somatic states in substance dependent individuals when pondering decisions with negative future consequences. Neuropsychologia 40: 1675-1689
32. Franklin TR, Acton PD, Maldjian JA, Gray JD, Croft JR, et al. (2002) Decreased gray matter concentration in the insular, orbitofrontal, cingulate, and temporal cortices of cocaine patients. Biol Psychiatry 51: 134-142
33. Ersche KD, Barnes A, Jones PS, Morein-Zamir S, Robbins TW, et al. (2011) Abnormal structure of frontostriatal brain systems is associated with aspects of impulsivity and compulsivity in cocaine dependence. Brain 134: 2013-2024
34. Pelloux Y, Murray JE, Everitt BJ (2013) Differential roles of the prefrontal cortical subregions and basolateral amygdala in compulsive cocaine seeking and relapse after voluntary abstinence in rats. Eur J Neurosci Jul 1 [Epub ahead of print]
35. Job MO, Tang A, Hall FS, Sora I, Uhl GR, et al. (2007) Mu (mu) opioid receptor regulation of ethanol-induced dopamine response in the ventral striatum. Evidence of genotype specific sexual dimorphic epistasis. Biol Psychiatry 62: 627-634
36. Chen Z, Karaplis AC, Ackerman SL, Pogribny IP, Melnyk S, et al. (2001) Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition. Hum Mol Genet 10: 433-443
37. Zhang H, Zang Y, Sun Y, Jin R, Wu H, et al. (2010) A new approach utilizing real-time qPCR to detect in vitro base excision repair. DNA Repair 9: 898-906
38. Ljungman M (2005) Activation of DNA damage signaling. Mutat Res 577: 203-216
39. Kolodner RD, Putnam CD, Myung K (2002) Maintenance of genome stability in Saccharomyces cerevisiae. Science 297: 552-557
40. Kanoh M, Takemura G, Misao J, Hayakawa Y, Aoyama T, et al. (1999) Significance of myocytes with positive DNA in situ nick end-labeling (TUNEL) in hearts with dilated cardiomyopathy. Not apoptosis but DNA repair. Circulation 99: 2757-2764
41. Elmore S (2007) Apoptosis. A review of programmed cell death. Toxicol Pathol 35: 495-516
42. Domazet-Damjanov D, Somayajulu-Ni M, Siyaram Pandey S (2009) Resistance of quiescent human diploid fibroblasts to high dose of external oxidative stress and induction of senescence. Open Biol J 2: 149-160
43. Loo DT (2011) In situ detection of apoptosis by the TUNEL assay. An overview of techniques. Methods Mol Biol 682: 3-13
44. Oomman S, Strahlendorf H, Finckbone V, Strahlendorf J (2005) Non-lethal active caspase-3 expression in Bergmann glia of postnatal rat cerebellum. Brain Res Dev Brain Res 160: 130-145
45. Finckbone V, Oomman SK, Strahlendorf HK, Strahlendorf JC (2009) Regional differences in the temporal expression of non-apoptotic caspase-3-positive Bergmann glial cells in the developing rat cerebellum. Front Neuroanat 3: 1-7
46. Davis CD, Uthus EO (2004) DNA methylation, cancer susceptibility, and nutrient interactions. Exp Biol Med 229: 988-995
47. Stover PJ (2009) One-carbon metabolism-genome interactions in folateassociated pathologies. J Nutr 139: 2402-2405
48. George O, Koob GF (2010) Individual differences in prefrontal cortex function and the transition from drug use to drug dependence. Neurosci Biobehav Rev 35: 232-247
49. Koob G, Kreek MJ (2007) Stress, dysregulation of drug reward pathways, and the transition to drug dependence. Am J Psych 164: 1149-1159
50. Sinha R (2008) Chronic stress, drug use, and vulnerability to addiction. Annals NY Acad Sci 1141: 105-130
51. Arnsten AF (2009) Stress signalling pathways that impair prefrontal cortex structure and function. Nat Rev Neurosci 10: 410-422
52. Filipovic' D, Zlatkovic' J, Inta D, Bjelobaba I, Stojiljkovic M, et al. (2011) Chronic isolation stress predisposes the frontal cortex but not the hippocampus to the potentially detrimental release of cytochrome c from mitochondria and the activation of caspase-3. J Neurosci Res 89: 1461-1470
53. Zlatković J, Todorović N, Bošković M, Pajović SB, Demajo M, et al. (2014) Different susceptibility of prefrontal cortex and hippocampus to oxidative stress following chronic social isolation stress. Mol Cell Biochem Mar 27 [Epub ahead of print]
54. García-Bueno B, Caso J, Pérez-Nievas BG, Lorenzo P, Leza JC (2006) Effects of peroxisome proliferator-activated receptor gamma agonists on brain glucose and glutamate transporters after stress in rats. Neuropsychopharmacology 32: 1251-1261
55. Meyerhoff DJ, Blumenfeld R, Truran D, Lindgren J, Flenniken D, et al. (2004) Effects of heavy drinking, binge drinking, and family history of alcoholism on regional brain metabolites. Alcoholism: Clinical & Experimental Research 28: 650e661
56. Schweizer TA, Vogel-Sprott M, Danckert J, Roy EA, Skakum A, et al. (2006) Neuropsychological profile of acute alcohol intoxication during ascending and descending blood alcohol concentrations. Neuropsychopharmacology 31: 1301e1309
57. Sircar R, Basak AK, Ashim K, Sircar D (2009) Repeated ethanol exposure affects the acquisition of spatial memory in adolescent female rats. Behavioural Brain Research 202: 225e231.