-
1
-
-
0024955886
-
Approaching the asymptote? Evolution and revolution in immunology
-
Janeway, Jr., C. A., (1989) Approaching the asymptote? Evolution and revolution in immunology. Cold Spring Harb. Symp. Quant. Biol. 54, 1-13.
-
(1989)
Cold Spring Harb. Symp. Quant. Biol.
, vol.54
, pp. 1-13
-
-
Janeway, C.A.1
-
3
-
-
84878232476
-
The history of Toll-like receptors-redefining innate immunity
-
O'Neill, L. A., Golenbock, D., Bowie, A. G. (2013) The history of Toll-like receptors-redefining innate immunity. Nat. Rev. Immunol. 13, 453-460.
-
(2013)
Nat. Rev. Immunol.
, vol.13
, pp. 453-460
-
-
O'Neill, L.A.1
Golenbock, D.2
Bowie, A.G.3
-
4
-
-
84865411904
-
C-Type lectin receptors orchestrate antifungal immunity
-
Hardison, S. E., Brown, G. D. (2012) C-Type lectin receptors orchestrate antifungal immunity. Nat. Immunol. 13, 817-822.
-
(2012)
Nat. Immunol.
, vol.13
, pp. 817-822
-
-
Hardison, S.E.1
Brown, G.D.2
-
5
-
-
84893702846
-
NOD proteins: Regulators of inflammation in health and disease
-
Philpott, D. J., Sorbara, M. T., Robertson, S. J., Croitoru, K., Girardin, S. E. (2014) NOD proteins: regulators of inflammation in health and disease. Nat. Rev. Immunol. 14, 9-23.
-
(2014)
Nat. Rev. Immunol.
, vol.14
, pp. 9-23
-
-
Philpott, D.J.1
Sorbara, M.T.2
Robertson, S.J.3
Croitoru, K.4
Girardin, S.E.5
-
6
-
-
84901310586
-
Mechanisms and functions of inflammasomes
-
Lamkanfi, M., Dixit, V. M. (2014) Mechanisms and functions of inflammasomes. Cell 157, 1013-1022.
-
(2014)
Cell
, vol.157
, pp. 1013-1022
-
-
Lamkanfi, M.1
Dixit, V.M.2
-
7
-
-
79651473582
-
NF-κB in immunobiology
-
Hayden, M. S., Ghosh, S. (2011) NF-κB in immunobiology. Cell Res. 21, 223-244.
-
(2011)
Cell Res.
, vol.21
, pp. 223-244
-
-
Hayden, M.S.1
Ghosh, S.2
-
8
-
-
84883199752
-
Mitogen-activated protein kinases in innate immunity
-
Arthur, J. S., Ley, S. C. (2013) Mitogen-activated protein kinases in innate immunity. Nat. Rev. Immunol. 13, 679-692.
-
(2013)
Nat. Rev. Immunol.
, vol.13
, pp. 679-692
-
-
Arthur, J.S.1
Ley, S.C.2
-
9
-
-
42649114059
-
The IRF family transcription factors in immunity and oncogenesis
-
Tamura, T., Yanai, H., Savitsky, D., Taniguchi, T. (2008) The IRF family transcription factors in immunity and oncogenesis. Annu. Rev. Immunol. 26, 535-584.
-
(2008)
Annu. Rev. Immunol.
, vol.26
, pp. 535-584
-
-
Tamura, T.1
Yanai, H.2
Savitsky, D.3
Taniguchi, T.4
-
10
-
-
84862883553
-
Information processing during phagocytosis
-
Underhill, D. M., Goodridge, H. S. (2012) Information processing during phagocytosis. Nat. Rev. Immunol. 12, 492-502.
-
(2012)
Nat. Rev. Immunol.
, vol.12
, pp. 492-502
-
-
Underhill, D.M.1
Goodridge, H.S.2
-
11
-
-
74549167783
-
Regulation of adaptive immunity by the innate immune system
-
Iwasaki, A., Medzhitov, R. (2010) Regulation of adaptive immunity by the innate immune system. Science 327, 291-295.
-
(2010)
Science
, vol.327
, pp. 291-295
-
-
Iwasaki, A.1
Medzhitov, R.2
-
12
-
-
5444262511
-
Toll-like receptor control of the adaptive immune responses
-
Iwasaki, A., Medzhitov, R. (2004) Toll-like receptor control of the adaptive immune responses. Nat. Immunol. 5, 987-995.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 987-995
-
-
Iwasaki, A.1
Medzhitov, R.2
-
13
-
-
82255191977
-
TLR-dependent T cell activation in autoimmunity
-
Mills, K. H. (2011) TLR-dependent T cell activation in autoimmunity. Nat. Rev. Immunol. 11, 807-822.
-
(2011)
Nat. Rev. Immunol.
, vol.11
, pp. 807-822
-
-
Mills, K.H.1
-
14
-
-
78650970845
-
Innate or adaptive immunity? The example of natural killer cells
-
Vivier, E., Raulet, D. H., Moretta, A., Caligiuri, M. A., Zitvogel, L., Lanier, L. L., Yokoyama, W. M., Ugolini, S. (2011) Innate or adaptive immunity? The example of natural killer cells. Science 331, 44-49.
-
(2011)
Science
, vol.331
, pp. 44-49
-
-
Vivier, E.1
Raulet, D.H.2
Moretta, A.3
Caligiuri, M.A.4
Zitvogel, L.5
Lanier, L.L.6
Yokoyama, W.M.7
Ugolini, S.8
-
15
-
-
77950365906
-
Nonresolving inflammation
-
Nathan, C., Ding, A. (2010) Nonresolving inflammation. Cell 140, 871-882.
-
(2010)
Cell
, vol.140
, pp. 871-882
-
-
Nathan, C.1
Ding, A.2
-
16
-
-
79953061608
-
Human TLRs and IL- 1Rs in host defense: Natural insights from evolutionary, epidemiological, and clinical genetics
-
Casanova, J. L., Abel, L., Quintana-Murci, L. (2011) Human TLRs and IL- 1Rs in host defense: natural insights from evolutionary, epidemiological, and clinical genetics. Annu. Rev. Immunol. 29, 447-491.
-
(2011)
Annu. Rev. Immunol.
, vol.29
, pp. 447-491
-
-
Casanova, J.L.1
Abel, L.2
Quintana-Murci, L.3
-
17
-
-
34447557009
-
Innate immunogenetics: A tool for exploring new frontiers of host defence
-
Bochud, P. Y., Bochud, M., Telenti, A., Calandra, T. (2007) Innate immunogenetics: a tool for exploring new frontiers of host defence. Lancet Infect. Dis. 7, 531-542.
-
(2007)
Lancet Infect. Dis.
, vol.7
, pp. 531-542
-
-
Bochud, P.Y.1
Bochud, M.2
Telenti, A.3
Calandra, T.4
-
18
-
-
84901014110
-
Natural selection and infectious disease in human populations
-
Karlsson, E. K., Kwiatkowski, D. P., Sabeti, P. C. (2014) Natural selection and infectious disease in human populations. Nat. Rev. Genet. 15, 379-393.
-
(2014)
Nat. Rev. Genet.
, vol.15
, pp. 379-393
-
-
Karlsson, E.K.1
Kwiatkowski, D.P.2
Sabeti, P.C.3
-
19
-
-
77952474987
-
Cellular heterogeneity: Do differences make a difference?
-
Altschuler, S. J., Wu, L. F. (2010) Cellular heterogeneity: do differences make a difference? Cell 141, 559-563.
-
(2010)
Cell
, vol.141
, pp. 559-563
-
-
Altschuler, S.J.1
Wu, L.F.2
-
20
-
-
77956651529
-
Bursts and pulses: Insights from single cell studies into transcriptional mechanisms
-
Chubb, J. R., Liverpool, T. B. (2010) Bursts and pulses: insights from single cell studies into transcriptional mechanisms. Curr. Opin. Genet. Dev. 20, 478-484.
-
(2010)
Curr. Opin. Genet. Dev.
, vol.20
, pp. 478-484
-
-
Chubb, J.R.1
Liverpool, T.B.2
-
21
-
-
33746788900
-
Quantum dot semiconductor nanocrystals for immunophenotyping by polychromatic flow cytometry
-
Chattopadhyay, P. K., Price, D. A., Harper, T. F., Betts, M. R., Yu, J., Gostick, E., Perfetto, S. P., Goepfert, P., Koup, R. A., De Rosa, S. C., Bruchez, M. P., Roederer, M. (2006) Quantum dot semiconductor nanocrystals for immunophenotyping by polychromatic flow cytometry. Nat. Med. 12, 972-977.
-
(2006)
Nat. Med.
, vol.12
, pp. 972-977
-
-
Chattopadhyay, P.K.1
Price, D.A.2
Harper, T.F.3
Betts, M.R.4
Yu, J.5
Gostick, E.6
Perfetto, S.P.7
Goepfert, P.8
Koup, R.A.9
De Rosa, S.C.10
Bruchez, M.P.11
Roederer, M.12
-
22
-
-
84862676726
-
A deep profiler's guide to cytometry
-
Bendall, S. C., Nolan, G. P., Roederer, M., Chattopadhyay, P. K. (2012) A deep profiler's guide to cytometry. Trends Immunol. 33, 323-332.
-
(2012)
Trends Immunol.
, vol.33
, pp. 323-332
-
-
Bendall, S.C.1
Nolan, G.P.2
Roederer, M.3
Chattopadhyay, P.K.4
-
23
-
-
80755168360
-
Genomic analysis at the single-cell level
-
Kalisky, T., Blainey, P., Quake, S. R. (2011) Genomic analysis at the single-cell level. Annu. Rev. Genet. 45, 431-445.
-
(2011)
Annu. Rev. Genet.
, vol.45
, pp. 431-445
-
-
Kalisky, T.1
Blainey, P.2
Quake, S.R.3
-
24
-
-
83255177150
-
Single-cell dissection of transcriptional heterogeneity in human colon tumors
-
Dalerba, P., Kalisky, T., Sahoo, D., Rajendran, P. S., Rothenberg, M. E., Leyrat, A. A., Sim, S., Okamoto, J., Johnston, D. M., Qian, D., Zabala, M., Bueno, J., Neff, N. F., Wang, J., Shelton, A. A., Visser, B., Hisamori, S., Shimono, Y., van de Wetering, M., Clevers, H., Clarke, M. F., Quake, S. R. (2011) Single-cell dissection of transcriptional heterogeneity in human colon tumors. Nat. Biotechnol. 29, 1120-1127.
-
(2011)
Nat. Biotechnol.
, vol.29
, pp. 1120-1127
-
-
Dalerba, P.1
Kalisky, T.2
Sahoo, D.3
Rajendran, P.S.4
Rothenberg, M.E.5
Leyrat, A.A.6
Sim, S.7
Okamoto, J.8
Johnston, D.M.9
Qian, D.10
Zabala, M.11
Bueno, J.12
Neff, N.F.13
Wang, J.14
Shelton, A.A.15
Visser, B.16
Hisamori, S.17
Shimono, Y.18
van de Wetering, M.19
Clevers, H.20
Clarke, M.F.21
Quake, S.R.22
more..
-
25
-
-
77951912210
-
Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst
-
Guo, G., Huss, M., Tong, G. Q., Wang, C., Li Sun, L., Clarke, N. D., Robson, P. (2010) Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Dev. Cell 18, 675-685.
-
(2010)
Dev. Cell
, vol.18
, pp. 675-685
-
-
Guo, G.1
Huss, M.2
Tong, G.Q.3
Wang, C.4
Li Sun, L.5
Clarke, N.D.6
Robson, P.7
-
26
-
-
84903185013
-
Singlecell RNA-seq reveals dynamic paracrine control of cellular variation
-
Shalek, A. K., Satija, R., Shuga, J., Trombetta, J. J., Gennert, D., Lu, D., Chen, P., Gertner, R. S., Gaublomme, J. T., Yosef, N., Schwartz, S., Fowler, B., Weaver, S., Wang, J., Wang, X., Ding, R., Raychowdhury, R., Friedman, N., Hacohen, N., Park, H., May, A. P., Regev, A. (2014) Singlecell RNA-seq reveals dynamic paracrine control of cellular variation. Nature 510, 363-369.
-
(2014)
Nature
, vol.510
, pp. 363-369
-
-
Shalek, A.K.1
Satija, R.2
Shuga, J.3
Trombetta, J.J.4
Gennert, D.5
Lu, D.6
Chen, P.7
Gertner, R.S.8
Gaublomme, J.T.9
Yosef, N.10
Schwartz, S.11
Fowler, B.12
Weaver, S.13
Wang, J.14
Wang, X.15
Ding, R.16
Raychowdhury, R.17
Friedman, N.18
Hacohen, N.19
Park, H.20
May, A.P.21
Regev, A.22
more..
-
27
-
-
84878997106
-
Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells
-
Shalek, A. K., Satija, R., Adiconis, X., Gertner, R. S., Gaublomme, J. T., Raychowdhury, R., Schwartz, S., Yosef, N., Malboeuf, C., Lu, D., Trombetta, J. J., Gennert, D., Gnirke, A., Goren, A., Hacohen, N., Levin, J. Z., Park, H., Regev, A. (2013) Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells. Nature 498, 236-240.
-
(2013)
Nature
, vol.498
, pp. 236-240
-
-
Shalek, A.K.1
Satija, R.2
Adiconis, X.3
Gertner, R.S.4
Gaublomme, J.T.5
Raychowdhury, R.6
Schwartz, S.7
Yosef, N.8
Malboeuf, C.9
Lu, D.10
Trombetta, J.J.11
Gennert, D.12
Gnirke, A.13
Goren, A.14
Hacohen, N.15
Levin, J.Z.16
Park, H.17
Regev, A.18
-
28
-
-
84893905629
-
Massively parallel single-cell RNA-seq for marker-free decomposition of tissues into cell types
-
Jaitin, D. A., Kenigsberg, E., Keren-Shaul, H., Elefant, N., Paul, F., Zaretsky, I., Mildner, A., Cohen, N., Jung, S., Tanay, A., Amit, I. (2014) Massively parallel single-cell RNA-seq for marker-free decomposition of tissues into cell types. Science 343, 776-779.
-
(2014)
Science
, vol.343
, pp. 776-779
-
-
Jaitin, D.A.1
Kenigsberg, E.2
Keren-Shaul, H.3
Elefant, N.4
Paul, F.5
Zaretsky, I.6
Mildner, A.7
Cohen, N.8
Jung, S.9
Tanay, A.10
Amit, I.11
-
29
-
-
84900529199
-
Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq
-
Treutlein, B., Brownfield, D. G., Wu, A. R., Neff, N. F., Mantalas, G. L., Espinoza, F. H., Desai, T. J., Krasnow, M. A., Quake, S. R. (2014) Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq. Nature 509, 371-375.
-
(2014)
Nature
, vol.509
, pp. 371-375
-
-
Treutlein, B.1
Brownfield, D.G.2
Wu, A.R.3
Neff, N.F.4
Mantalas, G.L.5
Espinoza, F.H.6
Desai, T.J.7
Krasnow, M.A.8
Quake, S.R.9
-
30
-
-
84904789189
-
Single-cell mass cytometry analysis of human tonsil T cell remodeling by varicella zoster virus
-
Sen, N., Mukherjee, G., Sen, A., Bendall, S. C., Sung, P., Nolan, G. P., Arvin, A. M. (2014) Single-cell mass cytometry analysis of human tonsil T cell remodeling by varicella zoster virus. Cell Reports 8, 633-645.
-
(2014)
Cell Reports
, vol.8
, pp. 633-645
-
-
Sen, N.1
Mukherjee, G.2
Sen, A.3
Bendall, S.C.4
Sung, P.5
Nolan, G.P.6
Arvin, A.M.7
-
31
-
-
33646591544
-
Transcriptional pulsing of a developmental gene
-
Chubb, J. R., Trcek, T., Shenoy, S. M., Singer, R. H. (2006) Transcriptional pulsing of a developmental gene. Curr. Biol. 16, 1018-1025.
-
(2006)
Curr. Biol.
, vol.16
, pp. 1018-1025
-
-
Chubb, J.R.1
Trcek, T.2
Shenoy, S.M.3
Singer, R.H.4
-
32
-
-
79955381895
-
Mammalian genes are transcribed with widely different bursting kinetics
-
Suter, D. M., Molina, N., Gatfield, D., Schneider, K., Schibler, U., Naef, F. (2011) Mammalian genes are transcribed with widely different bursting kinetics. Science 332, 472-474.
-
(2011)
Science
, vol.332
, pp. 472-474
-
-
Suter, D.M.1
Molina, N.2
Gatfield, D.3
Schneider, K.4
Schibler, U.5
Naef, F.6
-
33
-
-
0037119587
-
Stochastic gene expression in a single cell
-
Elowitz, M. B., Levine, A. J., Siggia, E. D., Swain, P. S. (2002) Stochastic gene expression in a single cell. Science 297, 1183-1186.
-
(2002)
Science
, vol.297
, pp. 1183-1186
-
-
Elowitz, M.B.1
Levine, A.J.2
Siggia, E.D.3
Swain, P.S.4
-
34
-
-
0036578645
-
Regulation of noise in the expression of a single gene
-
Ozbudak, E. M., Thattai, M., Kurtser, I., Grossman, A. D., van Oudenaarden, A. (2002) Regulation of noise in the expression of a single gene. Nat. Genet. 31, 69-73.
-
(2002)
Nat. Genet.
, vol.31
, pp. 69-73
-
-
Ozbudak, E.M.1
Thattai, M.2
Kurtser, I.3
Grossman, A.D.4
van Oudenaarden, A.5
-
35
-
-
0036790975
-
Intrinsic and extrinsic contributions to stochasticity in gene expression
-
Swain, P. S., Elowitz, M. B., Siggia, E. D. (2002) Intrinsic and extrinsic contributions to stochasticity in gene expression. Proc. Natl. Acad. Sci. USA 99, 12795-12800.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 12795-12800
-
-
Swain, P.S.1
Elowitz, M.B.2
Siggia, E.D.3
-
36
-
-
79960630264
-
Central dogma at the single-molecule level in living cells
-
Li, G. W., Xie, X. S. (2011) Central dogma at the single-molecule level in living cells. Nature 475, 308-315.
-
(2011)
Nature
, vol.475
, pp. 308-315
-
-
Li, G.W.1
Xie, X.S.2
-
37
-
-
84897059078
-
Early specification of CD8+ T lymphocyte fates during adaptive immunity revealed by single-cell gene-expression analyses
-
Arsenio, J., Kakaradov, B., Metz, P. J., Kim, S. H., Yeo, G. W., Chang, J. T. (2014) Early specification of CD8+ T lymphocyte fates during adaptive immunity revealed by single-cell gene-expression analyses. Nat. Immunol. 15, 365-372.
-
(2014)
Nat. Immunol.
, vol.15
, pp. 365-372
-
-
Arsenio, J.1
Kakaradov, B.2
Metz, P.J.3
Kim, S.H.4
Yeo, G.W.5
Chang, J.T.6
-
38
-
-
7144256245
-
Monoallelic expression of the interleukin-2 locus
-
Holländer, G. A., Zuklys, S., Morel, C., Mizoguchi, E., Mobisson, K., Simpson, S., Terhorst, C., Wishart, W., Golan, D. E., Bhan, A. K., Burakoff, S. J. (1998) Monoallelic expression of the interleukin-2 locus. Science 279, 2118-2121.
-
(1998)
Science
, vol.279
, pp. 2118-2121
-
-
Holländer, G.A.1
Zuklys, S.2
Morel, C.3
Mizoguchi, E.4
Mobisson, K.5
Simpson, S.6
Terhorst, C.7
Wishart, W.8
Golan, D.E.9
Bhan, A.K.10
Burakoff, S.J.11
-
39
-
-
84892179132
-
Single-cell RNA-seq reveals dynamic, random monoallelic gene expression in mammalian cells
-
Deng, Q., Ramsköld, D., Reinius, B., Sandberg, R. (2014) Single-cell RNA-seq reveals dynamic, random monoallelic gene expression in mammalian cells. Science 343, 193-196.
-
(2014)
Science
, vol.343
, pp. 193-196
-
-
Deng, Q.1
Ramsköld, D.2
Reinius, B.3
Sandberg, R.4
-
40
-
-
84920733410
-
Biased allelic expression in human primary fibroblast single cells
-
Borel, C., Ferreira, P. G., Santoni, F., Delaneau, O., Fort, A., Popadin, K. Y., Garieri, M., Falconnet, E., Ribaux, P., Guipponi, M., Padioleau, I., Carninci, P., Dermitzakis, E. T., Antonarakis, S. E. (2015) Biased allelic expression in human primary fibroblast single cells. Am. J. Hum. Genet. 96, 70-80.
-
(2015)
Am. J. Hum. Genet.
, vol.96
, pp. 70-80
-
-
Borel, C.1
Ferreira, P.G.2
Santoni, F.3
Delaneau, O.4
Fort, A.5
Popadin, K.Y.6
Garieri, M.7
Falconnet, E.8
Ribaux, P.9
Guipponi, M.10
Padioleau, I.11
Carninci, P.12
Dermitzakis, E.T.13
Antonarakis, S.E.14
-
41
-
-
25844433114
-
Gene expression profiling in single cells from the pancreatic islets of Langerhans reveals lognormal distribution of mRNA levels
-
Bengtsson, M., Ståhlberg, A., Rorsman, P., Kubista, M. (2005) Gene expression profiling in single cells from the pancreatic islets of Langerhans reveals lognormal distribution of mRNA levels. Genome Res. 15, 1388-1392.
-
(2005)
Genome Res.
, vol.15
, pp. 1388-1392
-
-
Bengtsson, M.1
Ståhlberg, A.2
Rorsman, P.3
Kubista, M.4
-
42
-
-
84882582801
-
Single-cell gene expression analysis reveals genetic associations masked in whole-tissue experiments
-
Wills, Q. F., Livak, K. J., Tipping, A. J., Enver, T., Goldson, A. J., Sexton, D. W., Holmes, C. (2013) Single-cell gene expression analysis reveals genetic associations masked in whole-tissue experiments. Nat. Biotechnol. 31, 748-752.
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 748-752
-
-
Wills, Q.F.1
Livak, K.J.2
Tipping, A.J.3
Enver, T.4
Goldson, A.J.5
Sexton, D.W.6
Holmes, C.7
-
43
-
-
84872968300
-
Innate lymphoid cells-how did we miss them?
-
Walker, J. A., Barlow, J. L., McKenzie, A. N. (2013) Innate lymphoid cells-how did we miss them? Nat. Rev. Immunol. 13, 75-87.
-
(2013)
Nat. Rev. Immunol.
, vol.13
, pp. 75-87
-
-
Walker, J.A.1
Barlow, J.L.2
McKenzie, A.N.3
-
44
-
-
77958185103
-
Nomenclature of monocytes and dendritic cells in blood
-
Ziegler-Heitbrock, L., Ancuta, P., Crowe, S., Dalod, M., Grau, V., Hart, D. N., Leenen, P. J., Liu, Y. J., MacPherson, G., Randolph, G. J., Scherberich, J., Schmitz, J., Shortman, K., Sozzani, S., Strobl, H., Zembala, M., Austyn, J. M., Lutz, M. B. (2010) Nomenclature of monocytes and dendritic cells in blood. Blood 116, e74-e80.
-
(2010)
Blood
, vol.116
, pp. e74-e80
-
-
Ziegler-Heitbrock, L.1
Ancuta, P.2
Crowe, S.3
Dalod, M.4
Grau, V.5
Hart, D.N.6
Leenen, P.J.7
Liu, Y.J.8
McPherson, G.9
Randolph, G.J.10
Scherberich, J.11
Schmitz, J.12
Shortman, K.13
Sozzani, S.14
Strobl, H.15
Zembala, M.16
Austyn, J.M.17
Lutz, M.B.18
-
45
-
-
80051567423
-
Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsets
-
Wong, K. L., Tai, J. J., Wong, W. C., Han, H., Sem, X., Yeap, W. H., Kourilsky, P., Wong, S. C. (2011) Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsets. Blood 118, e16-e31.
-
(2011)
Blood
, vol.118
, pp. e16-e31
-
-
Wong, K.L.1
Tai, J.J.2
Wong, W.C.3
Han, H.4
Sem, X.5
Yeap, W.H.6
Kourilsky, P.7
Wong, S.C.8
-
46
-
-
80053181958
-
SuperSAGE evidence for CD14++CD16+ monocytes as a third monocyte subset
-
Zawada, A. M., Rogacev, K. S., Rotter, B., Winter, P., Marell, R. R., Fliser, D., Heine, G. H. (2011) SuperSAGE evidence for CD14++CD16+ monocytes as a third monocyte subset. Blood 118, e50-e61.
-
(2011)
Blood
, vol.118
, pp. e50-e61
-
-
Zawada, A.M.1
Rogacev, K.S.2
Rotter, B.3
Winter, P.4
Marell, R.R.5
Fliser, D.6
Heine, G.H.7
-
47
-
-
84886419332
-
Genetic and environmental determinants of human NK cell diversity revealed by mass cytometry
-
Horowitz, A., Strauss-Albee, D. M., Leipold, M., Kubo, J., Nemat- Gorgani, N., Dogan, O. C., Dekker, C. L., Mackey, S., Maecker, H., Swan, G. E., Davis, M. M., Norman, P. J., Guethlein, L. A., Desai, M., Parham, P., Blish, C. A. (2013) Genetic and environmental determinants of human NK cell diversity revealed by mass cytometry. Sci. Transl. Med. 5, 208ra145.
-
(2013)
Sci. Transl. Med.
, vol.5
-
-
Horowitz, A.1
Strauss-Albee, D.M.2
Leipold, M.3
Kubo, J.4
Nemat-Gorgani, N.5
Dogan, O.C.6
Dekker, C.L.7
McKey, S.8
Maecker, H.9
Swan, G.E.10
Davis, M.M.11
Norman, P.J.12
Guethlein, L.A.13
Desai, M.14
Parham, P.15
Blish, C.A.16
-
48
-
-
34347256054
-
Microfluidic large-scale integration: The evolution of design rules for biological automation
-
Melin, J., Quake, S. R. (2007) Microfluidic large-scale integration: the evolution of design rules for biological automation. Annu. Rev. Biophys. Biomol. Struct. 36, 213-231.
-
(2007)
Annu. Rev. Biophys. Biomol. Struct.
, vol.36
, pp. 213-231
-
-
Melin, J.1
Quake, S.R.2
-
49
-
-
84876142711
-
Highly multiplexed quantitation of gene expression on single cells
-
Dominguez, M. H., Chattopadhyay, P. K., Ma, S., Lamoreaux, L., McDavid, A., Finak, G., Gottardo, R., Koup, R. A., Roederer, M. (2013) Highly multiplexed quantitation of gene expression on single cells. J. Immunol. Methods 391, 133-145.
-
(2013)
J. Immunol. Methods
, vol.391
, pp. 133-145
-
-
Dominguez, M.H.1
Chattopadhyay, P.K.2
Ma, S.3
Lamoreaux, L.4
McDavid, A.5
Finak, G.6
Gottardo, R.7
Koup, R.A.8
Roederer, M.9
-
50
-
-
84892687815
-
Single-cell technologies for monitoring immune systems
-
Chattopadhyay, P. K., Gierahn, T. M., Roederer, M., Love, J. C. (2014) Single-cell technologies for monitoring immune systems. Nat. Immunol. 15, 128-135.
-
(2014)
Nat. Immunol.
, vol.15
, pp. 128-135
-
-
Chattopadhyay, P.K.1
Gierahn, T.M.2
Roederer, M.3
Love, J.C.4
-
51
-
-
68849103521
-
Mass cytometry: Technique for real time single cell multitarget immunoassay based on inductively coupled plasma time-of-flight mass spectrometry
-
Bandura, D. R., Baranov, V. I., Ornatsky, O. I., Antonov, A., Kinach, R., Lou, X., Pavlov, S., Vorobiev, S., Dick, J. E., Tanner, S. D. (2009) Mass cytometry: technique for real time single cell multitarget immunoassay based on inductively coupled plasma time-of-flight mass spectrometry. Anal. Chem. 81, 6813-6822.
-
(2009)
Anal. Chem.
, vol.81
, pp. 6813-6822
-
-
Bandura, D.R.1
Baranov, V.I.2
Ornatsky, O.I.3
Antonov, A.4
Kinach, R.5
Lou, X.6
Pavlov, S.7
Vorobiev, S.8
Dick, J.E.9
Tanner, S.D.10
-
52
-
-
84884138622
-
Single-cell mass cytometry for analysis of immune system functional states
-
Bjornson, Z. B., Nolan, G. P., Fantl, W. J. (2013) Single-cell mass cytometry for analysis of immune system functional states. Curr. Opin. Immunol. 25, 484-494.
-
(2013)
Curr. Opin. Immunol.
, vol.25
, pp. 484-494
-
-
Bjornson, Z.B.1
Nolan, G.P.2
Fantl, W.J.3
-
53
-
-
77951174215
-
Evaluation of a 12-color flow cytometry panel to study lymphocyte, monocyte, and dendritic cell subsets in humans
-
Autissier, P., Soulas, C., Burdo, T. H., Williams, K. C. (2010) Evaluation of a 12-color flow cytometry panel to study lymphocyte, monocyte, and dendritic cell subsets in humans. Cytometry A 77, 410-419.
-
(2010)
Cytometry A
, vol.77
, pp. 410-419
-
-
Autissier, P.1
Soulas, C.2
Burdo, T.H.3
Williams, K.C.4
-
54
-
-
80054768631
-
Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE
-
Qiu, P., Simonds, E. F., Bendall, S. C., Gibbs, Jr., K. D., Bruggner, R. V., Linderman, M. D., Sachs, K., Nolan, G. P., Plevritis, S. K. (2011) Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE. Nat. Biotechnol. 29, 886-891.
-
(2011)
Nat. Biotechnol.
, vol.29
, pp. 886-891
-
-
Qiu, P.1
Simonds, E.F.2
Bendall, S.C.3
Gibbs, K.D.4
Bruggner, R.V.5
Linderman, M.D.6
Sachs, K.7
Nolan, G.P.8
Plevritis, S.K.9
-
55
-
-
84880280631
-
viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia
-
Amir, el-A. D., Davis, K. L., Tadmor, M. D., Simonds, E. F., Levine, J. H., Bendall, S. C., Shenfeld, D. K., Krishnaswamy, S., Nolan, G. P., Pe'er, D. (2013) viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia. Nat. Biotechnol. 31, 545-552.
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 545-552
-
-
Amir, E.-A.D.1
Davis, K.L.2
Tadmor, M.D.3
Simonds, E.F.4
Levine, J.H.5
Bendall, S.C.6
Shenfeld, D.K.7
Krishnaswamy, S.8
Nolan, G.P.9
Pe'er, D.10
-
56
-
-
84866096861
-
Multiplexed mass cytometry profiling of cellular states perturbed by small-molecule regulators
-
Bodenmiller, B., Zunder, E. R., Finck, R., Chen, T. J., Savig, E. S., Bruggner, R. V., Simonds, E. F., Bendall, S. C., Sachs, K., Krutzik, P. O., Nolan, G. P. (2012) Multiplexed mass cytometry profiling of cellular states perturbed by small-molecule regulators. Nat. Biotechnol. 30, 858-867.
-
(2012)
Nat. Biotechnol.
, vol.30
, pp. 858-867
-
-
Bodenmiller, B.1
Zunder, E.R.2
Finck, R.3
Chen, T.J.4
Savig, E.S.5
Bruggner, R.V.6
Simonds, E.F.7
Bendall, S.C.8
Sachs, K.9
Krutzik, P.O.10
Nolan, G.P.11
-
57
-
-
80052174976
-
Highthroughput microfluidic single-cell RT-qPCR
-
White, A. K., VanInsberghe, M., Petriv, O. I., Hamidi, M., Sikorski, D., Marra, M. A., Piret, J., Aparicio, S., Hansen, C. L. (2011) Highthroughput microfluidic single-cell RT-qPCR. Proc. Natl. Acad. Sci. USA 108, 13999-14004.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 13999-14004
-
-
White, A.K.1
VanInsberghe, M.2
Petriv, O.I.3
Hamidi, M.4
Sikorski, D.5
Marra, M.A.6
Piret, J.7
Aparicio, S.8
Hansen, C.L.9
-
58
-
-
79952332770
-
Quantitative miRNA expression analysis using fluidigm microfluidics dynamic arrays
-
Jang, J. S., Simon, V. A., Feddersen, R. M., Rakhshan, F., Schultz, D. A., Zschunke, M. A., Lingle, W. L., Kolbert, C. P., Jen, J. (2011) Quantitative miRNA expression analysis using fluidigm microfluidics dynamic arrays. BMC Genomics 12, 144.
-
(2011)
BMC Genomics
, vol.12
, pp. 144
-
-
Jang, J.S.1
Simon, V.A.2
Feddersen, R.M.3
Rakhshan, F.4
Schultz, D.A.5
Zschunke, M.A.6
Lingle, W.L.7
Kolbert, C.P.8
Jen, J.9
-
59
-
-
71649090975
-
High-throughput single nucleotide polymorphism genotyping using nanofluidic Dynamic Arrays
-
Wang, J., Lin, M., Crenshaw, A., Hutchinson, A., Hicks, B., Yeager, M., Berndt, S., Huang, W. Y., Hayes, R. B., Chanock, S. J., Jones, R. C., Ramakrishnan, R. (2009) High-throughput single nucleotide polymorphism genotyping using nanofluidic Dynamic Arrays. BMC Genomics 10, 561.
-
(2009)
BMC Genomics
, vol.10
, pp. 561
-
-
Wang, J.1
Lin, M.2
Crenshaw, A.3
Hutchinson, A.4
Hicks, B.5
Yeager, M.6
Berndt, S.7
Huang, W.Y.8
Hayes, R.B.9
Chanock, S.J.10
Jones, R.C.11
Ramakrishnan, R.12
-
60
-
-
78651304279
-
Whole-genome molecular haplotyping of single cells
-
Fan, H. C., Wang, J., Potanina, A., Quake, S. R. (2011) Whole-genome molecular haplotyping of single cells. Nat. Biotechnol. 29, 51-57.
-
(2011)
Nat. Biotechnol.
, vol.29
, pp. 51-57
-
-
Fan, H.C.1
Wang, J.2
Potanina, A.3
Quake, S.R.4
-
61
-
-
79958122357
-
A clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar T cells
-
Ma, C., Fan, R., Ahmad, H., Shi, Q., Comin-Anduix, B., Chodon, T., Koya, R. C., Liu, C. C., Kwong, G. A., Radu, C. G., Ribas, A., Heath, J. R. (2011) A clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar T cells. Nat. Med. 17, 738-743.
-
(2011)
Nat. Med.
, vol.17
, pp. 738-743
-
-
Ma, C.1
Fan, R.2
Ahmad, H.3
Shi, Q.4
Comin-Anduix, B.5
Chodon, T.6
Koya, R.C.7
Liu, C.C.8
Kwong, G.A.9
Radu, C.G.10
Ribas, A.11
Heath, J.R.12
-
62
-
-
84896284039
-
The present and future role of microfluidics in biomedical research
-
Sackmann, E. K., Fulton, A. L., Beebe, D. J. (2014) The present and future role of microfluidics in biomedical research. Nature 507, 181-189.
-
(2014)
Nature
, vol.507
, pp. 181-189
-
-
Sackmann, E.K.1
Fulton, A.L.2
Beebe, D.J.3
-
63
-
-
84862231072
-
Commercialization of microfluidic point-of-care diagnostic devices
-
Chin, C. D., Linder, V., Sia, S. K. (2012) Commercialization of microfluidic point-of-care diagnostic devices. Lab Chip 12, 2118-2134.
-
(2012)
Lab Chip
, vol.12
, pp. 2118-2134
-
-
Chin, C.D.1
Linder, V.2
Sia, S.K.3
-
64
-
-
84862756888
-
Single-cell mass cytometry adapted to measurements of the cell cycle
-
Behbehani, G. K., Bendall, S. C., Clutter, M. R., Fantl, W. J., Nolan, G. P. (2012) Single-cell mass cytometry adapted to measurements of the cell cycle. Cytometry A 81, 552-566.
-
(2012)
Cytometry A
, vol.81
, pp. 552-566
-
-
Behbehani, G.K.1
Bendall, S.C.2
Clutter, M.R.3
Fantl, W.J.4
Nolan, G.P.5
-
65
-
-
84896503384
-
Antigen-dependent integration of opposing proximal TCR-signaling cascades determines the functional fate of T lymphocytes
-
Wolchinsky, R., Hod-Marco, M., Oved, K., Shen-Orr, S. S., Bendall, S. C., Nolan, G. P., Reiter, Y. (2014) Antigen-dependent integration of opposing proximal TCR-signaling cascades determines the functional fate of T lymphocytes. J. Immunol. 192, 2109-2119.
-
(2014)
J. Immunol.
, vol.192
, pp. 2109-2119
-
-
Wolchinsky, R.1
Hod-Marco, M.2
Oved, K.3
Shen-Orr, S.S.4
Bendall, S.C.5
Nolan, G.P.6
Reiter, Y.7
-
66
-
-
84856278095
-
Cytometry by time-of-flight shows combinatorial cytokine expression and virus-specific cell niches within a continuum of CD8+ T cell phenotypes
-
Newell, E. W., Sigal, N., Bendall, S. C., Nolan, G. P., Davis, M. M. (2012) Cytometry by time-of-flight shows combinatorial cytokine expression and virus-specific cell niches within a continuum of CD8+ T cell phenotypes. Immunity 36, 142-152.
-
(2012)
Immunity
, vol.36
, pp. 142-152
-
-
Newell, E.W.1
Sigal, N.2
Bendall, S.C.3
Nolan, G.P.4
Davis, M.M.5
-
67
-
-
79955750055
-
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum
-
Bendall, S. C., Simonds, E. F., Qiu, P., Amir, A. D., Krutzik, P. O., Finck, R., Bruggner, R. V., Melamed, R., Trejo, A., Ornatsky, O. I., Balderas, R. S., Plevritis, S. K., Sachs, K., Pe'er, D., Tanner, S. D., Nolan, G. P. (2011) Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science 332, 687-696.
-
(2011)
Science
, vol.332
, pp. 687-696
-
-
Bendall, S.C.1
Simonds, E.F.2
Qiu, P.3
Amir, A.D.4
Krutzik, P.O.5
Finck, R.6
Bruggner, R.V.7
Melamed, R.8
Trejo, A.9
Ornatsky, O.I.10
Balderas, R.S.11
Plevritis, S.K.12
Sachs, K.13
Pe'er, D.14
Tanner, S.D.15
Nolan, G.P.16
-
68
-
-
84880289310
-
Combinatorial tetramer staining and mass cytometry analysis facilitate T-cell epitope mapping and characterization
-
Newell, E. W., Sigal, N., Nair, N., Kidd, B. A., Greenberg, H. B., Davis, M. M. (2013) Combinatorial tetramer staining and mass cytometry analysis facilitate T-cell epitope mapping and characterization. Nat. Biotechnol. 31, 623-629.
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 623-629
-
-
Newell, E.W.1
Sigal, N.2
Nair, N.3
Kidd, B.A.4
Greenberg, H.B.5
Davis, M.M.6
-
69
-
-
84912101829
-
CyTOF supports efficient detection of immune cell subsets from small samples
-
Yao, Y., Liu, R., Shin, M. S., Trentalange, M., Allore, H., Nassar, A., Kang, I., Pober, J. S., Montgomery, R. R. (2014) CyTOF supports efficient detection of immune cell subsets from small samples. J. Immunol. Methods 415, 1-5.
-
(2014)
J. Immunol. Methods
, vol.415
, pp. 1-5
-
-
Yao, Y.1
Liu, R.2
Shin, M.S.3
Trentalange, M.4
Allore, H.5
Nassar, A.6
Kang, I.7
Pober, J.S.8
Montgomery, R.R.9
-
70
-
-
84914106706
-
Single-cell mass cytometry of TCR signaling: Amplification of small initial differences results in low ERK activation in NOD mice
-
Mingueneau, M., Krishnaswamy, S., Spitzer, M. H., Bendall, S. C., Stone, E. L., Hedrick, S. M., Pe'er, D., Mathis, D., Nolan, G. P., Benoist, C. (2014) Single-cell mass cytometry of TCR signaling: amplification of small initial differences results in low ERK activation in NOD mice. Proc. Natl. Acad. Sci. USA 111, 16466-16471.
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 16466-16471
-
-
Mingueneau, M.1
Krishnaswamy, S.2
Spitzer, M.H.3
Bendall, S.C.4
Stone, E.L.5
Hedrick, S.M.6
Pe'er, D.7
Mathis, D.8
Nolan, G.P.9
Benoist, C.10
-
71
-
-
84919777275
-
CD161 defines a transcriptional and functional phenotype across distinct human T cell lineages
-
Fergusson, J. R., Smith, K. E., Fleming, V. M., Rajoriya, N., Newell, E. W., Simmons, R., Marchi, E., Björkander, S., Kang, Y. H., Swadling, L., Kurioka, A., Sahgal, N., Lockstone, H., Baban, D., Freeman, G. J., Sverremark-Ekström, E., Davis, M. M., Davenport, M. P., Venturi, V., Ussher, J. E., Willberg, C. B., Klenerman, P. (2014) CD161 defines a transcriptional and functional phenotype across distinct human T cell lineages. Cell Reports 9, 1075-1088.
-
(2014)
Cell Reports
, vol.9
, pp. 1075-1088
-
-
Fergusson, J.R.1
Smith, K.E.2
Fleming, V.M.3
Rajoriya, N.4
Newell, E.W.5
Simmons, R.6
Marchi, E.7
Björkander, S.8
Kang, Y.H.9
Swadling, L.10
Kurioka, A.11
Sahgal, N.12
Lockstone, H.13
Baban, D.14
Freeman, G.J.15
Sverremark-Ekström, E.16
Davis, M.M.17
Davenport, M.P.18
Venturi, V.19
Ussher, J.E.20
Willberg, C.B.21
Klenerman, P.22
more..
-
72
-
-
84881434960
-
Dietary gluten triggers concomitant activation of CD4+ and CD8+ αβ T cells and γδ T cells in celiac disease
-
Han, A., Newell, E. W., Glanville, J., Fernandez-Becker, N., Khosla, C., Chien, Y. H., Davis, M. M. (2013) Dietary gluten triggers concomitant activation of CD4+ and CD8+ αβ T cells and γδ T cells in celiac disease. Proc. Natl. Acad. Sci. USA 110, 13073-13078.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 13073-13078
-
-
Han, A.1
Newell, E.W.2
Glanville, J.3
Fernandez-Becker, N.4
Khosla, C.5
Chien, Y.H.6
Davis, M.M.7
-
73
-
-
84910117189
-
Coordinated regulation of NK receptor expression in the maturing human immune system
-
Strauss-Albee, D. M., Horowitz, A., Parham, P., Blish, C. A. (2014) Coordinated regulation of NK receptor expression in the maturing human immune system. J. Immunol. 193, 4871-4879.
-
(2014)
J. Immunol.
, vol.193
, pp. 4871-4879
-
-
Strauss-Albee, D.M.1
Horowitz, A.2
Parham, P.3
Blish, C.A.4
-
74
-
-
84908388625
-
Clinical recovery from surgery correlates with single-cell immune signatures
-
Gaudillière, B., Fragiadakis, G. K., Bruggner, R. V., Nicolau, M., Finck, R., Tingle, M., Silva, J., Ganio, E. A., Yeh, C. G., Maloney, W. J., Huddleston, J. I., Goodman, S. B., Davis, M. M., Bendall, S. C., Fantl, W. J., Angst, M. S., Nolan, G. P. (2014) Clinical recovery from surgery correlates with single-cell immune signatures. Sci. Transl. Med. 6, 255ra131.
-
(2014)
Sci. Transl. Med.
, vol.6
-
-
Gaudillière, B.1
Fragiadakis, G.K.2
Bruggner, R.V.3
Nicolau, M.4
Finck, R.5
Tingle, M.6
Silva, J.7
Ganio, E.A.8
Yeh, C.G.9
Maloney, W.J.10
Huddleston, J.I.11
Goodman, S.B.12
Davis, M.M.13
Bendall, S.C.14
Fantl, W.J.15
Angst, M.S.16
Nolan, G.P.17
-
75
-
-
84907984229
-
The split virus influenza vaccine rapidly activates immune cells through Fcγ receptors
-
O'Gorman, W. E., Huang, H., Wei, Y. L., Davis, K. L., Leipold, M. D., Bendall, S. C., Kidd, B. A., Dekker, C. L., Maecker, H. T., Chien, Y. H., Davis, M. M. (2014) The split virus influenza vaccine rapidly activates immune cells through Fcγ receptors. Vaccine 32, 5989-5997.
-
(2014)
Vaccine
, vol.32
, pp. 5989-5997
-
-
O'Gorman, W.E.1
Huang, H.2
Wei, Y.L.3
Davis, K.L.4
Leipold, M.D.5
Bendall, S.C.6
Kidd, B.A.7
Dekker, C.L.8
Maecker, H.T.9
Chien, Y.H.10
Davis, M.M.11
-
76
-
-
84908876253
-
A human vaccine strategy based on chimpanzee adenoviral and MVA vectors that primes, boosts, and sustains functional HCV-specific T cell memory
-
Swadling, L., Capone, S., Antrobus, R. D., Brown, A., Richardson, R., Newell, E. W., Halliday, J., Kelly, C., Bowen, D., Fergusson, J., Kurioka, A., Ammendola, V., Del Sorbo, M., Grazioli, F., Esposito, M. L., Siani, L., Traboni, C., Hill, A., Colloca, S., Davis, M., Nicosia, A., Cortese, R., Folgori, A., Klenerman, P., Barnes, E. (2014) A human vaccine strategy based on chimpanzee adenoviral and MVA vectors that primes, boosts, and sustains functional HCV-specific T cell memory. Sci. Transl. Med. 6, 261ra153.
-
(2014)
Sci. Transl. Med.
, vol.6
-
-
Swadling, L.1
Capone, S.2
Antrobus, R.D.3
Brown, A.4
Richardson, R.5
Newell, E.W.6
Halliday, J.7
Kelly, C.8
Bowen, D.9
Fergusson, J.10
Kurioka, A.11
Ammendola, V.12
Del Sorbo, M.13
Grazioli, F.14
Esposito, M.L.15
Siani, L.16
Traboni, C.17
Hill, A.18
Colloca, S.19
Davis, M.20
Nicosia, A.21
Cortese, R.22
Folgori, A.23
Klenerman, P.24
Barnes, E.25
more..
-
77
-
-
84911016319
-
High-dimensional analysis of the murine myeloid cell system
-
Becher, B., Schlitzer, A., Chen, J., Mair, F., Sumatoh, H. R., Teng, K. W., Low, D., Ruedl, C., Riccardi-Castagnoli, P., Poidinger, M., Greter, M., Ginhoux, F., Newell, E. W. (2014) High-dimensional analysis of the murine myeloid cell system. Nat. Immunol. 15, 1181-1189.
-
(2014)
Nat. Immunol.
, vol.15
, pp. 1181-1189
-
-
Becher, B.1
Schlitzer, A.2
Chen, J.3
Mair, F.4
Sumatoh, H.R.5
Teng, K.W.6
Low, D.7
Ruedl, C.8
Riccardi-Castagnoli, P.9
Poidinger, M.10
Greter, M.11
Ginhoux, F.12
Newell, E.W.13
-
78
-
-
84874418509
-
Innate immune response to homologous rotavirus infection in the small intestinal villous epithelium at single-cell resolution
-
Sen, A., Rothenberg, M. E., Mukherjee, G., Feng, N., Kalisky, T., Nair, N., Johnstone, I. M., Clarke, M. F., Greenberg, H. B. (2012) Innate immune response to homologous rotavirus infection in the small intestinal villous epithelium at single-cell resolution. Proc. Natl. Acad. Sci. USA 109, 20667-20672.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 20667-20672
-
-
Sen, A.1
Rothenberg, M.E.2
Mukherjee, G.3
Feng, N.4
Kalisky, T.5
Nair, N.6
Johnstone, I.M.7
Clarke, M.F.8
Greenberg, H.B.9
-
79
-
-
84876285802
-
Global burden of childhood pneumonia and diarrhoea
-
Walker, C. L., Rudan, I., Liu, L., Nair, H., Theodoratou, E., Bhutta, Z. A., O'Brien, K. L., Campbell, H., Black, R. E. (2013) Global burden of childhood pneumonia and diarrhoea. Lancet 381, 1405-1416.
-
(2013)
Lancet
, vol.381
, pp. 1405-1416
-
-
Walker, C.L.1
Rudan, I.2
Liu, L.3
Nair, H.4
Theodoratou, E.5
Bhutta, Z.A.6
O'Brien, K.L.7
Campbell, H.8
Black, R.E.9
-
81
-
-
84862908403
-
A genomic storm in critically injured humans
-
Xiao, W., Mindrinos, M. N., Seok, J., Cuschieri, J., Cuenca, A. G., Gao, H., Hayden, D. L., Hennessy, L., Moore, E. E., Minei, J. P., Bankey, P. E., Johnson, J. L., Sperry, J., Nathens, A. B., Billiar, T. R., West, M. A., Brownstein, B. H., Mason, P. H., Baker, H. V., Finnerty, C. C., Jeschke, M. G., López, M. C., Klein, M. B., Gamelli, R. L., Gibran, N. S., Arnoldo, B., Xu, W., Zhang, Y., Calvano, S. E., McDonald-Smith, G. P., Schoenfeld, D. A., Storey, J. D., Cobb, J. P., Warren, H. S., Moldawer, L. L., Herndon, D. N., Lowry, S. F., Maier, R. V., Davis, R. W., Tompkins, R. G.; Inflammation and Host Response to Injury Large-Scale Collaborative Research Program. (2011) A genomic storm in critically injured humans. J. Exp. Med. 208, 2581-2590.
-
(2011)
J. Exp. Med.
, vol.208
, pp. 2581-2590
-
-
Xiao, W.1
Mindrinos, M.N.2
Seok, J.3
Cuschieri, J.4
Cuenca, A.G.5
Gao, H.6
Hayden, D.L.7
Hennessy, L.8
Moore, E.E.9
Minei, J.P.10
Bankey, P.E.11
Johnson, J.L.12
Sperry, J.13
Nathens, A.B.14
Billiar, T.R.15
West, M.A.16
Brownstein, B.H.17
Mason, P.H.18
Baker, H.V.19
Finnerty, C.C.20
Jeschke, M.G.21
López, M.C.22
Klein, M.B.23
Gamelli, R.L.24
Gibran, N.S.25
Arnoldo, B.26
Xu, W.27
Zhang, Y.28
Calvano, S.E.29
McDonald-Smith, G.P.30
Schoenfeld, D.A.31
Storey, J.D.32
Cobb, J.P.33
Warren, H.S.34
Moldawer, L.L.35
Herndon, D.N.36
Lowry, S.F.37
Maier, R.V.38
Davis, R.W.39
Tompkins, R.G.40
Inflammation and Host Response to Injury Large-Scale Collaborative Research Program41
more..
-
82
-
-
84255183707
-
The search for effective therapy for sepsis: Back to the drawing board?
-
Angus, D. C. (2011) The search for effective therapy for sepsis: back to the drawing board? JAMA 306, 2614-2615.
-
(2011)
JAMA
, vol.306
, pp. 2614-2615
-
-
Angus, D.C.1
-
83
-
-
84862749338
-
Sepsis studies need new direction
-
Cohen, J., Opal, S., Calandra, T. (2012) Sepsis studies need new direction. Lancet Infect. Dis. 12, 503-505.
-
(2012)
Lancet Infect. Dis.
, vol.12
, pp. 503-505
-
-
Cohen, J.1
Opal, S.2
Calandra, T.3
-
84
-
-
84863693768
-
Trial failure prompts soul-searching for critical-care specialists
-
Dolgin, E. (2012) Trial failure prompts soul-searching for critical-care specialists. Nat. Med. 18, 1000.
-
(2012)
Nat. Med.
, vol.18
, pp. 1000
-
-
Dolgin, E.1
-
85
-
-
84865302435
-
The rise and fall of drotrecogin alfa (activated)
-
Vincent, J. L. (2012) The rise and fall of drotrecogin alfa (activated). Lancet Infect. Dis. 12, 649-651.
-
(2012)
Lancet Infect. Dis.
, vol.12
, pp. 649-651
-
-
Vincent, J.L.1
-
86
-
-
84861706642
-
Septic shock-evaluating another failed treatment
-
Wenzel, R. P., Edmond, M. B. (2012) Septic shock-evaluating another failed treatment. N. Engl. J. Med. 366, 2122-2124.
-
(2012)
N. Engl. J. Med.
, vol.366
, pp. 2122-2124
-
-
Wenzel, R.P.1
Edmond, M.B.2
-
87
-
-
84863712115
-
After Xigris, researchers look to new targets to combat sepsis
-
Williams, S. C. (2012) After Xigris, researchers look to new targets to combat sepsis. Nat. Med. 18, 1001.
-
(2012)
Nat. Med.
, vol.18
, pp. 1001
-
-
Williams, S.C.1
-
88
-
-
84874457770
-
Genomic responses in mouse models poorly mimic human inflammatory diseases
-
Seok, J., Warren, H. S., Cuenca, A. G., Mindrinos, M. N., Baker, H. V., Xu, W., Richards, D. R., McDonald-Smith, G. P., Gao, H., Hennessy, L., Finnerty, C. C., López, C. M., Honari, S., Moore, E. E., Minei, J. P., Cuschieri, J., Bankey, P. E., Johnson, J. L., Sperry, J., Nathens, A. B., Billiar, T. R., West, M. A., Jeschke, M. G., Klein, M. B., Gamelli, R. L., Gibran, N. S., Brownstein, B. H., Miller-Graziano, C., Calvano, S. E., Mason, P. H., Cobb, J. P., Rahme, L. G., Lowry, S. F., Maier, R. V., Moldawer, L. L., Herndon, D. N., Davis, R. W., Xiao, W., Tompkins, R. G.; Inflammation and Host Response to Injury, Large Scale Collaborative Research Program. (2013) Genomic responses in mouse models poorly mimic human inflammatory diseases. Proc. Natl. Acad. Sci. USA 110, 3507-3512.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 3507-3512
-
-
Seok, J.1
Warren, H.S.2
Cuenca, A.G.3
Mindrinos, M.N.4
Baker, H.V.5
Xu, W.6
Richards, D.R.7
McDonald-Smith, G.P.8
Gao, H.9
Hennessy, L.10
Finnerty, C.C.11
López, C.M.12
Honari, S.13
Moore, E.E.14
Minei, J.P.15
Cuschieri, J.16
Bankey, P.E.17
Johnson, J.L.18
Sperry, J.19
Nathens, A.B.20
Billiar, T.R.21
West, M.A.22
Jeschke, M.G.23
Klein, M.B.24
Gamelli, R.L.25
Gibran, N.S.26
Brownstein, B.H.27
Miller-Graziano, C.28
Calvano, S.E.29
Mason, P.H.30
Cobb, J.P.31
Rahme, L.G.32
Lowry, S.F.33
Maier, R.V.34
Moldawer, L.L.35
Herndon, D.N.36
Davis, R.W.37
Xiao, W.38
Tompkins, R.G.39
Inflammation and Host Response to Injury, Large Scale Collaborative Research Program,40
more..
-
89
-
-
84921727957
-
Genomic responses in mouse models greatly mimic human inflammatory diseases
-
Takao, K., Miyakawa, T. (2014) Genomic responses in mouse models greatly mimic human inflammatory diseases. Proc. Natl. Acad. Sci. USA 112, 1167-1172.
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.112
, pp. 1167-1172
-
-
Takao, K.1
Miyakawa, T.2
-
90
-
-
84876800337
-
Macrophage biology in development, homeostasis and disease
-
Wynn, T. A., Chawla, A., Pollard, J. W. (2013) Macrophage biology in development, homeostasis and disease. Nature 496, 445-455.
-
(2013)
Nature
, vol.496
, pp. 445-455
-
-
Wynn, T.A.1
Chawla, A.2
Pollard, J.W.3
-
91
-
-
56749174940
-
Exploring the full spectrum of macrophage activation
-
Mosser, D. M., Edwards, J. P. (2008) Exploring the full spectrum of macrophage activation. Nat. Rev. Immunol. 8, 958-969.
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 958-969
-
-
Mosser, D.M.1
Edwards, J.P.2
-
92
-
-
84894102230
-
Transcriptome-based network analysis reveals a spectrum model of human macrophage activation
-
Xue, J., Schmidt, S. V., Sander, J., Draffehn, A., Krebs, W., Quester, I., De Nardo, D., Gohel, T. D., Emde, M., Schmidleithner, L., Ganesan, H., Nino-Castro, A., Mallmann, M. R., Labzin, L., Theis, H., Kraut, M., Beyer, M., Latz, E., Freeman, T. C., Ulas, T., Schultze, J. L. (2014) Transcriptome-based network analysis reveals a spectrum model of human macrophage activation. Immunity 40, 274-288.
-
(2014)
Immunity
, vol.40
, pp. 274-288
-
-
Xue, J.1
Schmidt, S.V.2
Sander, J.3
Draffehn, A.4
Krebs, W.5
Quester, I.6
De Nardo, D.7
Gohel, T.D.8
Emde, M.9
Schmidleithner, L.10
Ganesan, H.11
Nino-Castro, A.12
Mallmann, M.R.13
Labzin, L.14
Theis, H.15
Kraut, M.16
Beyer, M.17
Latz, E.18
Freeman, T.C.19
Ulas, T.20
Schultze, J.L.21
more..
-
93
-
-
84886017663
-
Temporal dynamics and transcriptional control using single-cell gene expression analysis
-
Kouno, T., de Hoon, M., Mar, J. C., Tomaru, Y., Kawano, M., Carninci, P., Suzuki, H., Hayashizaki, Y., Shin, J. W. (2013) Temporal dynamics and transcriptional control using single-cell gene expression analysis. Genome Biol. 14, R118.
-
(2013)
Genome Biol.
, vol.14
-
-
Kouno, T.1
de Hoon, M.2
Mar, J.C.3
Tomaru, Y.4
Kawano, M.5
Carninci, P.6
Suzuki, H.7
Hayashizaki, Y.8
Shin, J.W.9
-
94
-
-
79955021823
-
Single-cell gene-expression profiling reveals qualitatively distinct CD8 T cells elicited by different gene-based vaccines
-
Flatz, L., Roychoudhuri, R., Honda, M., Filali-Mouhim, A., Goulet, J. P., Kettaf, N., Lin, M., Roederer, M., Haddad, E. K., Sékaly, R. P., Nabel, G. J. (2011) Single-cell gene-expression profiling reveals qualitatively distinct CD8 T cells elicited by different gene-based vaccines. Proc. Natl. Acad. Sci. USA 108, 5724-5729.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 5724-5729
-
-
Flatz, L.1
Roychoudhuri, R.2
Honda, M.3
Filali-Mouhim, A.4
Goulet, J.P.5
Kettaf, N.6
Lin, M.7
Roederer, M.8
Haddad, E.K.9
Sékaly, R.P.10
Nabel, G.J.11
-
95
-
-
84873506978
-
Designing tomorrow's vaccines
-
Nabel, G. J. (2013) Designing tomorrow's vaccines. N. Engl. J. Med. 368, 551-560.
-
(2013)
N. Engl. J. Med.
, vol.368
, pp. 551-560
-
-
Nabel, G.J.1
-
96
-
-
84876804736
-
The global distribution and burden of dengue
-
Bhatt, S., Gething, P. W., Brady, O. J., Messina, J. P., Farlow, A. W., Moyes, C. L., Drake, J. M., Brownstein, J. S., Hoen, A. G., Sankoh, O., Myers, M. F., George, D. B., Jaenisch, T., Wint, G. R., Simmons, C. P., Scott, T. W., Farrar, J. J., Hay, S. I. (2013) The global distribution and burden of dengue. Nature 496, 504-507.
-
(2013)
Nature
, vol.496
, pp. 504-507
-
-
Bhatt, S.1
Gething, P.W.2
Brady, O.J.3
Messina, J.P.4
Farlow, A.W.5
Moyes, C.L.6
Drake, J.M.7
Brownstein, J.S.8
Hoen, A.G.9
Sankoh, O.10
Myers, M.F.11
George, D.B.12
Jaenisch, T.13
Wint, G.R.14
Simmons, C.P.15
Scott, T.W.16
Farrar, J.J.17
Hay, S.I.18
-
97
-
-
84907417476
-
Ebola-underscoring the global disparities in health care resources
-
Fauci, A. S. (2014) Ebola-underscoring the global disparities in health care resources. N. Engl. J. Med. 371, 1084-1086.
-
(2014)
N. Engl. J. Med.
, vol.371
, pp. 1084-1086
-
-
Fauci, A.S.1
|