-
1
-
-
0036407229
-
Physics and application of microfluidics in biology
-
Beebe, D. J., Mensing, G. A. & Walker, G. M. Physics and application of microfluidics in biology. Annu. Rev. Biomed. Eng. 4, 261-286 (2002).
-
(2002)
Annu. Rev. Biomed. Eng.
, vol.4
, pp. 261-286
-
-
Beebe, D.J.1
Mensing, G.A.2
Walker, G.M.3
-
2
-
-
0141557513
-
Microfluidics in structural biology: Smaller, faster better
-
Hansen, C. & Quake, S. R. Microfluidics in structural biology: smaller, faster better. Curr. Opin. Struct. Biol. 13, 538-544 (2003).
-
(2003)
Curr. Opin. Struct. Biol.
, vol.13
, pp. 538-544
-
-
Hansen, C.1
Quake, S.R.2
-
3
-
-
33747086959
-
Microfluidic diagnostic technologies for global public health
-
Yager, P. et al. Microfluidic diagnostic technologies for global public health. Nature 442, 412-418 (2006).
-
(2006)
Nature
, vol.442
, pp. 412-418
-
-
Yager, P.1
-
4
-
-
33747116681
-
Cells on chips
-
El-Ali, J., Sorger, P. & Jensen, K. Cells on chips. Nature 442, 403-411 (2006).
-
(2006)
Nature
, vol.442
, pp. 403-411
-
-
El-Ali, J.1
Sorger, P.2
Jensen, K.3
-
5
-
-
33747117373
-
The origins and the future of microfluidics
-
Whitesides, G. M. The origins and the future of microfluidics. Nature 442, 368-373 (2006).
-
(2006)
Nature
, vol.442
, pp. 368-373
-
-
Whitesides, G.M.1
-
6
-
-
0025207507
-
Miniaturized total chemical-analysis systems - A novel concept for chemical sensing
-
Manz, A., Graber, N. & Widmer, H. M. Miniaturized total chemical-analysis systems - a novel concept for chemical sensing. Sens. Actuators B 1, 244-248 (1990).
-
(1990)
Sens. Actuators B
, vol.1
, pp. 244-248
-
-
Manz, A.1
Graber, N.2
Widmer, H.M.3
-
7
-
-
0037096666
-
Micro total analysis systems 1. Introduction, theory, and technology
-
This pioneering publication described the concept of a mTAS device
-
Reyes, D. R., Iossifidis, D., Auroux, P.-A. & Manz, A. Micro total analysis systems. 1. Introduction, theory, and technology. Anal. Chem. 74, 2623-2636 (2002). This pioneering publication described the concept of a mTAS device.
-
(2002)
Anal. Chem.
, vol.74
, pp. 2623-2636
-
-
Reyes, D.R.1
Iossifidis, D.2
Auroux, P.-A.3
Manz, A.4
-
8
-
-
0141920675
-
A passive pumping method for microfluidic devices
-
Describes amethod to passively pumpfluids within microchannels using only a micropipette
-
Walker, G. A passive pumping method for microfluidic devices. Lab Chip 2, 131-134 (2002). Describes amethod to passively pumpfluids within microchannels using only a micropipette.
-
(2002)
Lab Chip
, vol.2
, pp. 131-134
-
-
Walker, G.1
-
9
-
-
77950374540
-
Capillary based patterning of cellular communities in laterally open channels
-
Lee, S. H. et al. Capillary based patterning of cellular communities in laterally open channels. Anal. Chem. 82, 2900-2906 (2010).
-
(2010)
Anal. Chem.
, vol.82
, pp. 2900-2906
-
-
Lee, S.H.1
-
10
-
-
84863478659
-
Streamlining immunoassays with immiscible filtrations assisted by surface tension
-
Berry, S. M., Maccoux, L. J. & Beebe, D. J. Streamlining immunoassays with immiscible filtrations assisted by surface tension. Anal. Chem. 84, 5518-5523 (2012).
-
(2012)
Anal. Chem.
, vol.84
, pp. 5518-5523
-
-
Berry, S.M.1
Maccoux, L.J.2
Beebe, D.J.3
-
11
-
-
0037455351
-
Formation of dispersions using 'flow focusing' in microchannels
-
Anna, S. L., Bontoux, N. & Stone, H. A. Formation of dispersions using 'flow focusing' in microchannels. Appl. Phys. Lett. 82, 364-366 (2003).
-
(2003)
Appl. Phys. Lett.
, vol.82
, pp. 364-366
-
-
Anna, S.L.1
Bontoux, N.2
Stone, H.A.3
-
12
-
-
84870175062
-
Cool, or simple and cheap? Why not both?
-
Whitesides, G. M. Cool, or simple and cheap? Why not both? Lab Chip 13, 11-13 (2012).
-
(2012)
Lab Chip
, vol.13
, pp. 11-13
-
-
Whitesides, G.M.1
-
13
-
-
34547616470
-
Microfluidics: In search of a killer application
-
Blow, N. Microfluidics: in search of a killer application. Nature Methods 4, 665-670 (2007).
-
(2007)
Nature Methods
, vol.4
, pp. 665-670
-
-
Blow, N.1
-
14
-
-
69549138236
-
Hype, hope and hubris: The quest for the killer application in microfluidics
-
Becker, H. Hype, hope and hubris: the quest for the killer application in microfluidics. Lab Chip 9, 2119-2122 (2009).
-
(2009)
Lab Chip
, vol.9
, pp. 2119-2122
-
-
Becker, H.1
-
15
-
-
0343841187
-
The chemotactic effect of mixtures of antibody and antigen on polymorphonuclear leucocytes
-
Boyden, S. The chemotactic effect of mixtures of antibody and antigen on polymorphonuclear leucocytes. J. Exp. Med. 115, 453-466 (1962).
-
(1962)
J. Exp. Med.
, vol.115
, pp. 453-466
-
-
Boyden, S.1
-
16
-
-
0017660115
-
Ability of polymorphonuclear leukocytes to orient in gradients of chemotactic factors
-
Zigmond, S. H. Ability of polymorphonuclear leukocytes to orient in gradients of chemotactic factors. J. Cell Biol. 75, 606-616 (1977).
-
(1977)
J. Cell Biol.
, vol.75
, pp. 606-616
-
-
Zigmond, S.H.1
-
17
-
-
0025788971
-
A new direct-viewing chemotaxis chamber
-
Zicha, D., Dunn, G. A. & Brown, A. F. A new direct-viewing chemotaxis chamber. J. Cell Sci. 99, 769-775 (1991).
-
(1991)
J. Cell Sci.
, vol.99
, pp. 769-775
-
-
Zicha, D.1
Dunn, G.A.2
Brown, A.F.3
-
18
-
-
78650766712
-
An improved chamber for direct visualisation of chemotaxis
-
Muinonen-Martin, A. J. A., Veltman, D. M. D., Kalna, G. G. & Insall, R. H. R. An improved chamber for direct visualisation of chemotaxis. PLoS ONE 5, e15309 (2010).
-
(2010)
PLoS ONE
, vol.5
-
-
Muinonen-Martin, A.J.A.1
Veltman, D.M.D.2
Kalna, G.G.3
Insall, R.H.R.4
-
19
-
-
37349027919
-
Biomolecular gradients in cell culture systems
-
A detailed review of microfluidic chemical gradient generators
-
Keenan, T. M.& Folch, A. Biomolecular gradients in cell culture systems. Lab Chip 8, 34-57 (2008). A detailed review of microfluidic chemical gradient generators.
-
(2008)
Lab Chip
, vol.8
, pp. 34-57
-
-
Keenan, T.M.1
Folch, A.2
-
20
-
-
77955630835
-
Microfluidic technologies for temporal perturbations of chemotaxis
-
Irimia, D. Microfluidic technologies for temporal perturbations of chemotaxis. Annu. Rev. Biomed. Eng. 12, 259-284 (2010).
-
(2010)
Annu. Rev. Biomed. Eng.
, vol.12
, pp. 259-284
-
-
Irimia, D.1
-
21
-
-
0035132216
-
Theoretical analysis ofmolecular diffusion in pressuredriven laminar flow in microfluidic channels
-
Kamholz, A. E.&Yager, P. Theoretical analysis ofmolecular diffusion in pressuredriven laminar flow in microfluidic channels. Biophys. J. 80, 155-160 (2001).
-
(2001)
Biophys. J.
, vol.80
, pp. 155-160
-
-
Kamholz, A.E.1
Yager, P.2
-
22
-
-
0034293766
-
Generation of solution and surface gradients using microfluidic systems
-
Jeon, N. L. et al. Generation of solution and surface gradients using microfluidic systems. Langmuir 16, 8311-8316 (2000).
-
(2000)
Langmuir
, vol.16
, pp. 8311-8316
-
-
Jeon, N.L.1
-
23
-
-
33646746703
-
Universal microfluidic gradient generator
-
Irimia, D., Geba, D. A. & Toner, M. Universal microfluidic gradient generator. Anal. Chem. 78, 3472-3477 (2006).
-
(2006)
Anal. Chem.
, vol.78
, pp. 3472-3477
-
-
Irimia, D.1
Geba, D.A.2
Toner, M.3
-
24
-
-
50249188454
-
Microfluidics meet cell biology: Bridging the gap by validation and application of microscale techniques for cell biological assays
-
Paguirigan, A. L. & Beebe, D. J. Microfluidics meet cell biology: bridging the gap by validation and application of microscale techniques for cell biological assays. Bioessays 30, 811-821 (2008).
-
(2008)
Bioessays
, vol.30
, pp. 811-821
-
-
Paguirigan, A.L.1
Beebe, D.J.2
-
25
-
-
77955630510
-
Burn injury reduces neutrophil directional migration speed in microfluidic devices
-
Butler, K. L. et al. Burn injury reduces neutrophil directional migration speed in microfluidic devices. PLoS ONE 5, e11921 (2010).
-
(2010)
PLoS ONE
, vol.5
-
-
Butler, K.L.1
-
26
-
-
84867314609
-
Microfluidic kit-on-A-lid: A versatile platform for neutrophil chemotaxis assays
-
Sackmann, E. K. et al. Microfluidic kit-on-a-lid: a versatile platform for neutrophil chemotaxis assays. Blood 120, e45-e53 (2012).
-
(2012)
Blood
, vol.120
-
-
Sackmann, E.K.1
-
27
-
-
78149253340
-
Open access microfluidic device for the study of cell migration during chemotaxis
-
Jowhar, D.,Wright, G., Samson, P. C., Wikswo, J. P.&Janetopoulos, C.Open access microfluidic device for the study of cell migration during chemotaxis. Integr. Biol. 2, 648-658 (2010).
-
(2010)
Integr. Biol.
, vol.2
, pp. 648-658
-
-
Jowhar, D.1
Wright, G.2
Samson, P.C.3
Wikswo, J.P.4
Janetopoulos, C.5
-
30
-
-
0024101674
-
A piezoelectric micropump based on micromachining of silicon
-
Van Lintel, H., Vandepol, F. & Bouwstra, S. A piezoelectric micropump based on micromachining of silicon. Sens. Actuators 15, 153-167 (1988).
-
(1988)
Sens. Actuators
, vol.15
, pp. 153-167
-
-
Van Lintel, H.1
Vandepol, F.2
Bouwstra, S.3
-
31
-
-
11944262834
-
Capillary electrophoresis and sample injection systems integrated on a planar glass chip
-
Harrison, D. J., Manz, A., Fan, Z. H., Ludi, H. & Widmer, H. M. Capillary electrophoresis and sample injection systems integrated on a planar glass chip. Anal. Chem. 64, 1926-1932 (1992).
-
(1992)
Anal. Chem.
, vol.64
, pp. 1926-1932
-
-
Harrison, D.J.1
Manz, A.2
Fan, Z.H.3
Ludi, H.4
Widmer, H.M.5
-
32
-
-
0016117359
-
Submicrometer resolution replication of relief patterns for integrated optics
-
An early example of replicating microfluidic structures with elastomer materials
-
Aumiller, G. D., Chandross, E. A., Tomlinson, W. J. & Weber, H. P. Submicrometer resolution replication of relief patterns for integrated optics. J. Appl. Phys. 45, 4557-4562 (1974). An early example of replicating microfluidic structures with elastomer materials.
-
(1974)
J. Appl. Phys.
, vol.45
, pp. 4557-4562
-
-
Aumiller, G.D.1
Chandross, E.A.2
Tomlinson, W.J.3
Weber, H.P.4
-
33
-
-
0024705033
-
Novel method of cell fusion in field constriction area in fluid integrated circuit
-
Masuda, M., Masao, W. & Nanba, T. Novel method of cell fusion in field constriction area in fluid integrated circuit. IEEE Trans. Ind. Appl. 25, 732-737 (1989).
-
(1989)
IEEE Trans. Ind. Appl.
, vol.25
, pp. 732-737
-
-
Masuda, M.1
Masao, W.2
Nanba, T.3
-
34
-
-
0032403465
-
Rapid prototyping of microfluidic systems in poly(dimethylsiloxane)
-
Duffy, D. C. D., McDonald, J. C. J., Schueller, O. J. O. & Whitesides, G. M. G. Rapid prototyping of microfluidic systems in poly(dimethylsiloxane). Anal. Chem. 70, 4974-4984 (1998).
-
(1998)
Anal. Chem.
, vol.70
, pp. 4974-4984
-
-
Duffy, D.C.D.1
McDonald, J.C.J.2
Schueller, O.J.O.3
Whitesides, G.M.G.4
-
35
-
-
84857944649
-
Engineers are fromPDMS-land, Biologists are from Polystyrenia
-
Berthier, E., Young, E. W. K.&Beebe, D. Engineers are fromPDMS-land, Biologists are from Polystyrenia. Lab Chip 12, 1224-1237 (2012).
-
(2012)
Lab Chip
, vol.12
, pp. 1224-1237
-
-
Berthier, E.1
Young, E.W.K.2
Beebe, D.3
-
36
-
-
0000454965
-
Direct measurement of interfacial interactions between semispherical lenses and flat sheets of poly(dimethylsiloxane) and their chemical derivatives
-
Chaudhury, M. K. & Whitesides, G. M. Direct measurement of interfacial interactions between semispherical lenses and flat sheets of poly(dimethylsiloxane) and their chemical derivatives. Langmuir 7, 1013-1025 (1991).
-
(1991)
Langmuir
, vol.7
, pp. 1013-1025
-
-
Chaudhury, M.K.1
Whitesides, G.M.2
-
37
-
-
0025447127
-
On the aging of oxygen plasma-treated polydimethylsiloxane surfaces
-
Morra, M. et al. On the aging of oxygen plasma-treated polydimethylsiloxane surfaces. J. Colloid Interface Sci. 137, 11-24 (1990).
-
(1990)
J. Colloid Interface Sci.
, vol.137
, pp. 11-24
-
-
Morra, M.1
-
38
-
-
79551661682
-
Assaying stem cell mechanobiology on microfabricated elastomeric substrates with geometrically modulated rigidity
-
Yang, M. T., Fu, J., Wang, Y.-K., Desai, R. A. & Chen, C. S. Assaying stem cell mechanobiology on microfabricated elastomeric substrates with geometrically modulated rigidity. Nature Protocols 6, 187-213 (2011).
-
(2011)
Nature Protocols
, vol.6
, pp. 187-213
-
-
Yang, M.T.1
Fu, J.2
Wang, Y.-K.3
Desai, R.A.4
Chen, C.S.5
-
39
-
-
78650186789
-
Engineered materialsand the cellular microenvironment: A strengthening interface between cell biology and bioengineering
-
Choi, C. K., Breckenridge, M. T.&Chen, C. S. Engineered materialsand the cellular microenvironment: a strengthening interface between cell biology and bioengineering. Trends Cell Biol. 20, 705-714 (2010).
-
(2010)
Trends Cell Biol.
, vol.20
, pp. 705-714
-
-
Choi, C.K.1
Breckenridge, M.T.2
Chen, C.S.3
-
40
-
-
0034711410
-
From micro- to nanofabrication with soft materials
-
Quake, S. R. From micro- to nanofabrication with soft materials. Science 290, 1536-1540 (2000).
-
(2000)
Science
, vol.290
, pp. 1536-1540
-
-
Quake, S.R.1
-
41
-
-
0034615958
-
Monolithic microfabricated valves and pumps by multilayer soft lithography
-
Unger, M. A. Monolithic microfabricated valves and pumps by multilayer soft lithography. Science 288, 113-116 (2000).
-
(2000)
Science
, vol.288
, pp. 113-116
-
-
Unger, M.A.1
-
42
-
-
69549135426
-
Biological implications of polydimethylsiloxane-based microfluidic cell culture
-
A study that details the biological implications of using PDMS in cell biology research
-
Regehr, K. J. et al. Biological implications of polydimethylsiloxane- based microfluidic cell culture. Lab Chip 9, 2132-2139 (2009). A study that details the biological implications of using PDMS in cell biology research.
-
(2009)
Lab Chip
, vol.9
, pp. 2132-2139
-
-
Regehr, K.J.1
-
43
-
-
0344737989
-
Solvent compatibility of poly(dimethylsiloxane)-based microfluidic devices
-
Lee, J. N., Park, C. & Whitesides, G. M. Solvent compatibility of poly(dimethylsiloxane)-based microfluidic devices. Anal. Chem. 75, 6544-6554 (2003).
-
(2003)
Anal. Chem.
, vol.75
, pp. 6544-6554
-
-
Lee, J.N.1
Park, C.2
Whitesides, G.M.3
-
44
-
-
33846246380
-
PDMS absorption of small molecules and consequences in microfluidic applications
-
Toepke, M. W. & Beebe, D. J. PDMS absorption of small molecules and consequences in microfluidic applications. Lab Chip 6, 1484-1486 (2006).
-
(2006)
Lab Chip
, vol.6
, pp. 1484-1486
-
-
Toepke, M.W.1
Beebe, D.J.2
-
45
-
-
42549137103
-
Managing evaporation for more robust microscale assays. Part 1. Volume loss in high throughput assays
-
Berthier, E., Warrick, J., Yu, H. & Beebe, D. J. Managing evaporation for more robust microscale assays. Part 1. Volume loss in high throughput assays. Lab Chip 8, 852-859 (2008).
-
(2008)
Lab Chip
, vol.8
, pp. 852-859
-
-
Berthier, E.1
Warrick, J.2
Yu, H.3
Beebe, D.J.4
-
46
-
-
4043079192
-
The effect of hyperosmotic pressure on antibody production and gene expression in the GS-NS0 cell line
-
Wu, M.-H. M., Dimopoulos, G. G., Mantalaris, A. A. & Varley, J. J. The effect of hyperosmotic pressure on antibody production and gene expression in the GS-NS0 cell line. Biotechnol. Appl. Biochem. 40, 41-46 (2004).
-
(2004)
Biotechnol. Appl. Biochem.
, vol.40
, pp. 41-46
-
-
Wu, M.-H.M.1
Dimopoulos, G.G.2
Mantalaris, A.A.3
Varley, J.J.4
-
47
-
-
0032442233
-
Effects of CO2 and osmolality on hybridoma cells: Growth, metabolism and monoclonal antibody production
-
deZengotita, V., Kimura, R. & Miller, W. M. Effects of CO2 and osmolality on hybridoma cells: growth, metabolism and monoclonal antibody production. Cytotechnology 28, 213-227 (1998).
-
(1998)
Cytotechnology
, vol.28
, pp. 213-227
-
-
Dezengotita, V.1
Kimura, R.2
Miller, W.M.3
-
48
-
-
33846999007
-
Characterization and resolution of evaporation-mediated osmolality shifts that constrain microfluidic cell culture in poly(dimethylsiloxane) devices
-
Heo, Y. S. et al. Characterization and resolution of evaporation-mediated osmolality shifts that constrain microfluidic cell culture in poly(dimethylsiloxane) devices. Anal. Chem. 79, 1126-1134 (2007).
-
(2007)
Anal. Chem.
, vol.79
, pp. 1126-1134
-
-
Heo, Y.S.1
-
49
-
-
33644841800
-
Handheld recirculation system and customized media for microfluidic cell culture
-
Futai, N., Gu, W., Song, J. W. & Takayama, S. Handheld recirculation system and customized media for microfluidic cell culture. Lab Chip 6, 149-154 (2006).
-
(2006)
Lab Chip
, vol.6
, pp. 149-154
-
-
Futai, N.1
Gu, W.2
Song, J.W.3
Takayama, S.4
-
50
-
-
0348038716
-
Poly (dimethylsiloxane)(PDMS) and silicon hybrid biochip for bacterial culture
-
Chang, W.-J., Akin, D., Sedlak, M., Ladisch, M. R. & Bashir, R. Poly (dimethylsiloxane)(PDMS) and silicon hybrid biochip for bacterial culture. Biomed. Microdevices 5, 281-290 (2003).
-
(2003)
Biomed. Microdevices
, vol.5
, pp. 281-290
-
-
Chang, W.-J.1
Akin, D.2
Sedlak, M.3
Ladisch, M.R.4
Bashir, R.5
-
51
-
-
70349303095
-
-
Becker, H. It's the economy
-
Becker, H. It's the economy Lab Chip 9, 2759-2762 (2009).
-
(2009)
Lab Chip
, vol.9
, pp. 2759-2762
-
-
-
52
-
-
34248210771
-
When PDMS isn't the best
-
Mukhopadhyay, R. When PDMS isn't the best. Anal. Chem. 79, 3248-3253 (2007).
-
(2007)
Anal. Chem.
, vol.79
, pp. 3248-3253
-
-
Mukhopadhyay, R.1
-
53
-
-
79961171532
-
Microfluidics-based diagnostics of infectious diseases in the developing world
-
A study that diagnosed HIV from blood samples in Rwanda using a simple microfluidic chip
-
Chin, C. D. et al. Microfluidics-based diagnostics of infectious diseases in the developing world. Nature Med. 17, 1015-1019 (2011). A study that diagnosed HIV from blood samples in Rwanda using a simple microfluidic chip.
-
(2011)
Nature Med.
, vol.17
, pp. 1015-1019
-
-
Chin, C.D.1
-
54
-
-
0034329607
-
Surface modification of poly(methyl methacrylate) used in the fabrication of microanalytical devices
-
Henry, A. C. et al. Surface modification of poly(methyl methacrylate) used in the fabrication of microanalytical devices. Anal. Chem. 72, 5331-5337 (2000).
-
(2000)
Anal. Chem.
, vol.72
, pp. 5331-5337
-
-
Henry, A.C.1
-
55
-
-
70349920767
-
A rapid prototyping method for polymer microfluidics with fixed aspect ratio and 3D tapered channels
-
Browne, A. W., Rust, M. J., Jung, W., Lee, S. H. & Ahn, C. H. A rapid prototyping method for polymer microfluidics with fixed aspect ratio and 3D tapered channels. Lab Chip 9, 2941-2946 (2009).
-
(2009)
Lab Chip
, vol.9
, pp. 2941-2946
-
-
Browne, A.W.1
Rust, M.J.2
Jung, W.3
Lee, S.H.4
Ahn, C.H.5
-
56
-
-
0033732466
-
Hot embossing as a method for the fabrication of polymer high aspect ratio structures
-
Becker, H. & Heim, U. Hot embossing as a method for the fabrication of polymer high aspect ratio structures. Sens. Actuators A 83, 130-135 (2000).
-
(2000)
Sens. Actuators A
, vol.83
, pp. 130-135
-
-
Becker, H.1
Heim, U.2
-
57
-
-
0031308143
-
Fabrication of plastic microfluid channels by imprinting methods
-
Martynova, L. et al. Fabrication of plastic microfluid channels by imprinting methods. Anal. Chem. 69, 4783-4789 (1997).
-
(1997)
Anal. Chem.
, vol.69
, pp. 4783-4789
-
-
Martynova, L.1
-
58
-
-
78651505715
-
Hot embossing of plastic microfluidic devices using poly(dimethylsiloxane) molds
-
Goral, V. N., Hsieh, Y.-C., Petzold, O. N., Faris, R. A. & Yuen, P. K. Hot embossing of plastic microfluidic devices using poly(dimethylsiloxane) molds. J. Micromech. Microeng. 21, 017002 (2011).
-
(2011)
J. Micromech. Microeng.
, vol.21
, pp. 017002
-
-
Goral, V.N.1
Hsieh, Y.-C.2
Petzold, O.N.3
Faris, R.A.4
Yuen, P.K.5
-
59
-
-
79951622265
-
Rapid prototyping of arrayed microfluidic systems in polystyrene for cell-based assays
-
Young, E. W. K. et al. Rapid prototyping of arrayed microfluidic systems in polystyrene for cell-based assays. Anal. Chem. 83, 1408-1417 (2011).
-
(2011)
Anal. Chem.
, vol.83
, pp. 1408-1417
-
-
Young, E.W.K.1
-
60
-
-
80052246612
-
Benchtop micromolding of polystyrene by soft lithography
-
Wang, Y. et al. Benchtop micromolding of polystyrene by soft lithography. Lab Chip 11, 3089-3097 (2011).
-
(2011)
Lab Chip
, vol.11
, pp. 3089-3097
-
-
Wang, Y.1
-
61
-
-
84871817041
-
Assessment of enhanced autofluorescence and impact on cell microscopy for microfabricated thermoplastic devices
-
Young, E. W. K., Berthier, E. & Beebe, D. J. Assessment of enhanced autofluorescence and impact on cell microscopy for microfabricated thermoplastic devices. Anal. Chem. 85, 44-49 (2013).
-
(2013)
Anal. Chem.
, vol.85
, pp. 44-49
-
-
Young, E.W.K.1
Berthier, E.2
Beebe, D.J.3
-
62
-
-
82555199849
-
Flexible microfluidic cloth-based analytical devices using a low-cost wax patterning technique
-
Nilghaz, A. et al. Flexible microfluidic cloth-based analytical devices using a low-cost wax patterning technique. Lab Chip 12, 209-218 (2011).
-
(2011)
Lab Chip
, vol.12
, pp. 209-218
-
-
Nilghaz, A.1
-
63
-
-
21844471002
-
Point-of-care immunotesting: Approaching the analytical performance of central laboratorymethods
-
von Lode, P. Point-of-care immunotesting: approaching the analytical performance of central laboratorymethods. Clin. Biochem. 38, 591-606 (2005).
-
(2005)
Clin. Biochem.
, vol.38
, pp. 591-606
-
-
Von Lode, P.1
-
64
-
-
75749113741
-
Diagnostics for the developing world: Microfluidic paper-based analytical devices
-
Martinez, A. W., Phillips, S. T., Whitesides, G. M. & Carrilho, E. Diagnostics for the developing world: microfluidic paper-based analytical devices. Anal. Chem. 82, 3-10 (2010).
-
(2010)
Anal. Chem.
, vol.82
, pp. 3-10
-
-
Martinez, A.W.1
Phillips, S.T.2
Whitesides, G.M.3
Carrilho, E.4
-
65
-
-
68849107869
-
Understanding wax printing: A simple micropatterning process for paper-based microfluidics
-
Carrilho, E., Martinez, A. W. & Whitesides, G. M. Understanding wax printing: a simple micropatterning process for paper-based microfluidics. Anal. Chem. 81, 7091-7095 (2009).
-
(2009)
Anal. Chem.
, vol.81
, pp. 7091-7095
-
-
Carrilho, E.1
Martinez, A.W.2
Whitesides, G.M.3
-
66
-
-
56549094092
-
FLASH: A rapid method for prototyping paper-based microfluidic devices
-
Martinez, A. W., Phillips, S. T., Wiley, B. J., Gupta, M. & Whitesides, G. M. FLASH: A rapid method for prototyping paper-based microfluidic devices. Lab Chip 8, 2146-2150 (2008).
-
(2008)
Lab Chip
, vol.8
, pp. 2146-2150
-
-
Martinez, A.W.1
Phillips, S.T.2
Wiley, B.J.3
Gupta, M.4
Whitesides, G.M.5
-
67
-
-
51949106700
-
Inkjet-printed microfluidicmultianalyte chemical sensing paper
-
Abe, K., Suzuki, K.& Citterio, D. Inkjet-printed microfluidicmultianalyte chemical sensing paper. Anal. Chem. 80, 6928-6934 (2008).
-
(2008)
Anal. Chem.
, vol.80
, pp. 6928-6934
-
-
Abe, K.1
Suzuki, K.2
Citterio, D.3
-
68
-
-
78650406348
-
Flexographically printed fluidic structures in paper
-
Olkkonen, J., Lehtinen, K. & Erho, T. Flexographically printed fluidic structures in paper. Anal. Chem. 82, 10246-10250 (2010).
-
(2010)
Anal. Chem.
, vol.82
, pp. 10246-10250
-
-
Olkkonen, J.1
Lehtinen, K.2
Erho, T.3
-
69
-
-
84861122286
-
Two-dimensional paper network formatthat enables simplemultistep assays for use in low-resource settings in the context of malaria antigen detection
-
Fu, E. et al.Two-dimensional paper network formatthat enables simplemultistep assays for use in low-resource settings in the context of malaria antigen detection. Anal. Chem. 84, 4574-4579 (2012).
-
(2012)
Anal Chem.
, vol.84
, pp. 4574-4579
-
-
Fu, E.1
-
70
-
-
58149378331
-
Three-dimensional microfluidic devices fabricated in layered paper and tape
-
A review of advancements in mPAD devices for diagnostics in developing regions
-
Martinez, A. W., Phillips, S. T. & Whitesides, G. M. Three-dimensional microfluidic devices fabricated in layered paper and tape. Proc. Natl Acad. Sci. USA 105, 19606-19611 (2008). A review of advancements in mPAD devices for diagnostics in developing regions.
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 19606-19611
-
-
Martinez, A.W.1
Phillips, S.T.2
Whitesides, G.M.3
-
71
-
-
84870227903
-
Development of automated paper-based devices for sequential multistep sandwich enzymelinked immunosorbent assays using inkjet printing
-
Apilux, A., Ukita, Y., Chikae, M., Chailapakul, O. & Takamura, Y. Development of automated paper-based devices for sequential multistep sandwich enzymelinked immunosorbent assays using inkjet printing. Lab Chip 13, 126-135 (2012).
-
(2012)
Lab Chip
, vol.13
, pp. 126-135
-
-
Apilux, A.1
Ukita, Y.2
Chikae, M.3
Chailapakul, O.4
Takamura, Y.5
-
72
-
-
84891700461
-
Microfluidic CD41 and CD81 T lymphocyte counters for point-of-care HIV diagnostics using whole blood
-
Watkins, N. N. et al. Microfluidic CD41 and CD81 T lymphocyte counters for point-of-care HIV diagnostics using whole blood. Sci. Transl. Med. 5, 214ra170 (2013).
-
(2013)
Sci. Transl. Med.
, vol.5
-
-
Watkins, N.N.1
-
73
-
-
79961171532
-
Microfluidics-based diagnostics of infectious diseases in the developing world
-
Chin, C. D. et al. Microfluidics-based diagnostics of infectious diseases in the developing world. Nature Med. 17, 1015-1019 (2011).
-
(2011)
Nature Med.
, vol.17
, pp. 1015-1019
-
-
Chin, C.D.1
-
74
-
-
77956430960
-
Clinical microfluidics for neutrophil genomics and proteomics
-
This study investigated the relationship between protein/genetic information and the clinical condition of burn patients using a simple microfluidic device
-
Kotz, K. T. et al. Clinical microfluidics for neutrophil genomics and proteomics. Nature Med. 16, 1042-1047 (2010). This study investigated the relationship between protein/genetic information and the clinical condition of burn patients using a simple microfluidic device.
-
(2010)
Nature Med.
, vol.16
, pp. 1042-1047
-
-
Kotz, K.T.1
-
75
-
-
82355184365
-
Microfluidics-based capture of human neutrophils for expression analysis in blood and bronchoalveolar lavage
-
Warner, E. A. et al. Microfluidics-based capture of human neutrophils for expression analysis in blood and bronchoalveolar lavage. Lab. Invest. 91, 1787-1795 (2011).
-
(2011)
Lab. Invest.
, vol.91
, pp. 1787-1795
-
-
Warner, E.A.1
-
76
-
-
0014834557
-
Single-step separation of red blood cells, granulocytes and mononuclear leukocytes on discontinuous density gradients of Ficoll-Hypaque
-
Bach, M. K. & Brashler, J. R. Single-step separation of red blood cells, granulocytes and mononuclear leukocytes on discontinuous density gradients of Ficoll-Hypaque. Exp. Cell Res. 61, 387-396 (1970).
-
(1970)
Exp. Cell Res.
, vol.61
, pp. 387-396
-
-
Bach, M.K.1
Brashler, J.R.2
-
77
-
-
79955369547
-
One-step purification of nucleic acid for gene expression analysis via Immiscible Filtration Assisted by Surface Tension (IFAST)
-
Berry, S. M., Alarid, E. T. & Beebe, D. J. One-step purification of nucleic acid for gene expression analysis via Immiscible Filtration Assisted by Surface Tension (IFAST). Lab Chip 11, 1747-1753 (2011).
-
(2011)
Lab Chip
, vol.11
, pp. 1747-1753
-
-
Berry, S.M.1
Alarid, E.T.2
Beebe, D.J.3
-
78
-
-
84855654376
-
Purification of cell subpopulations via immiscible filtration assisted by surface tension (IFAST)
-
Berry, S. M., Strotman, L. N., Kueck, J. D., Alarid, E. T. & Beebe, D. J. Purification of cell subpopulations via immiscible filtration assisted by surface tension (IFAST). Biomed. Microdevices 13, 1033-1042 (2011).
-
(2011)
Biomed. Microdevices
, vol.13
, pp. 1033-1042
-
-
Berry, S.M.1
Strotman, L.N.2
Kueck, J.D.3
Alarid, E.T.4
Beebe, D.J.5
-
79
-
-
79951469554
-
Pfizer slashes R&D
-
Cressey, D. Pfizer slashes R&D. Nature 470, 154 (2011).
-
(2011)
Nature
, vol.470
, pp. 154
-
-
Cressey, D.1
-
80
-
-
0037374498
-
The price of innovation: New estimates of drug development costs
-
DiMasi, J. A., Hansen, R. W. & Grabowski, H. G. The price of innovation: new estimates of drug development costs. J. Health Econ. 22, 151-185 (2003).
-
(2003)
J. Health Econ.
, vol.22
, pp. 151-185
-
-
Dimasi, J.A.1
Hansen, R.W.2
Grabowski, H.G.3
-
81
-
-
79952267810
-
Traditional drug-discoverymodel ripe for reform
-
Cressey, D. Traditional drug-discoverymodel ripe for reform. Nature 471, 17-18 (2011).
-
(2011)
Nature
, vol.471
, pp. 17-18
-
-
Cressey, D.1
-
82
-
-
77649234756
-
Howto improveR&Dproductivity: The pharmaceutical industry's grand challenge
-
Paul, S. M. et al. Howto improveR&Dproductivity: the pharmaceutical industry's grand challenge. Nature Rev. Drug Discov. 9, 203-214 (2010).
-
(2010)
Nature Rev. Drug Discov.
, vol.9
, pp. 203-214
-
-
Paul, S.M.1
-
83
-
-
84892550520
-
Academia and big pharma united
-
Ljunggren, H. G. Academia and big pharma united. Sci. Transl. Med. 6, 217ed1 (2014).
-
(2014)
Sci. Transl. Med.
, vol.6
-
-
Ljunggren, H.G.1
-
84
-
-
42549115139
-
An integrated microfluidic system for long-term perfusion culture and on-line monitoring of intestinal tissue models
-
Kimura, H., Yamamoto, T., Sakai, H., Sakai, Y.& Fujii, T. An integrated microfluidic system for long-term perfusion culture and on-line monitoring of intestinal tissue models. Lab Chip 8, 741-746 (2008).
-
(2008)
Lab Chip
, vol.8
, pp. 741-746
-
-
Kimura, H.1
Yamamoto, T.2
Sakai, H.3
Sakai, Y.4
Fujii, T.5
-
85
-
-
77954038080
-
Reconstituting organ-level lung functions on a chip
-
Huh, D. et al. Reconstituting organ-level lung functions on a chip. Science 328, 1662-1668 (2010).
-
(2010)
Science
, vol.328
, pp. 1662-1668
-
-
Huh, D.1
-
86
-
-
84855468373
-
In vitro modeling of the microvascular occlusion and thrombosis that occur in hematologic diseases using microfluidic technology
-
This study utilized precisely patterned microvessels to diagnose vasco-occlusions in patient samples
-
Tsai, M. et al. In vitro modeling of the microvascular occlusion and thrombosis that occur in hematologic diseases using microfluidic technology. J. Clin. Invest. 122, 408-418 (2012). This study utilized precisely patterned microvessels to diagnose vasco-occlusions in patient samples.
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 408-418
-
-
Tsai, M.1
-
87
-
-
84870672834
-
Tubeless microfluidic angiogenesis assay with three-dimensional endothelial-lined microvessels
-
Bischel, L. L., Young, E. W. K., Mader, B. R. & Beebe, D. J. Tubeless microfluidic angiogenesis assay with three-dimensional endothelial-lined microvessels. Biomaterials 34, 1471-1477 (2013).
-
(2013)
Biomaterials
, vol.34
, pp. 1471-1477
-
-
Bischel, L.L.1
Young, E.W.K.2
Mader, B.R.3
Beebe, D.J.4
-
88
-
-
80053086676
-
Fluid forces control endothelial sprouting
-
Song, J. W. & Munn, L. L. Fluid forces control endothelial sprouting. Proc. Natl Acad. Sci. USA 108, 15342-15347 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 15342-15347
-
-
Song, J.W.1
Munn, L.L.2
-
89
-
-
59649105005
-
A multipurpose microfluidic device designed to mimic microenvironment gradients and develop targeted cancer therapeutics
-
Walsh, C. L. et al. A multipurpose microfluidic device designed to mimic microenvironment gradients and develop targeted cancer therapeutics. Lab Chip 9, 545-554 (2009).
-
(2009)
Lab Chip
, vol.9
, pp. 545-554
-
-
Walsh, C.L.1
-
90
-
-
84865293346
-
Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function
-
This study describes a system that more closely mimics tumour cell intravasation in vitro compared to standard cell biology techniques such as modified Transwell assays
-
Zervantonakis, I. K. et al. Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function. Proc. Natl Acad. Sci. USA 109, 13515-13520 (2012). This study describes a system that more closely mimics tumour cell intravasation in vitro compared to standard cell biology techniques such as modified Transwell assays.
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 13515-13520
-
-
Zervantonakis, I.K.1
-
91
-
-
79953731991
-
Transition to invasion in breast cancer: A microfluidic in vitro model enables examination of spatial and temporal effects
-
Sung, K. E. et al. Transition to invasion in breast cancer: a microfluidic in vitro model enables examination of spatial and temporal effects. Integr. Biol. 3, 439-450 (2011).
-
(2011)
Integr. Biol.
, vol.3
, pp. 439-450
-
-
Sung, K.E.1
-
92
-
-
77951884924
-
A multi-layer microfluidic device for efficient culture and analysis of renal tubular cells
-
Jang, K.-J. & Suh, K.-Y. A multi-layer microfluidic device for efficient culture and analysis of renal tubular cells. Lab Chip 10, 36-42 (2010).
-
(2010)
Lab Chip
, vol.10
, pp. 36-42
-
-
Jang, K.-J.1
Suh, K.-Y.2
-
93
-
-
81355146382
-
From 3D cell culture to organs-on-chips
-
Huh, D., Hamilton, G. A. & Ingber, D. E. From 3D cell culture to organs-on-chips. Trends Cell Biol. 21, 745-754 (2011).
-
(2011)
Trends Cell Biol.
, vol.21
, pp. 745-754
-
-
Huh, D.1
Hamilton, G.A.2
Ingber, D.E.3
-
94
-
-
84857696896
-
A biophysical indicator of vaso-occlusive risk in sickle cell disease
-
Wood, D. K., Soriano, A.,Mahadevan, L., Higgins, J. M.&Bhatia, S. N. A biophysical indicator of vaso-occlusive risk in sickle cell disease. Sci. Transl. Med. 4, 123ra26 (2012).
-
(2012)
Sci. Transl. Med.
, vol.4
-
-
Wood, D.K.1
Soriano, A.2
Mahadevan, L.3
Higgins, J.M.4
Bhatia, S.N.5
-
95
-
-
79958083996
-
Pipette-friendly laminar flow patterning for cell-based assays
-
Berthier, E., Warrick, J.& Casavant, B. Pipette-friendly laminar flow patterning for cell-based assays. Lab Chip 11, 2060-2065 (2011).
-
(2011)
Lab Chip
, vol.11
, pp. 2060-2065
-
-
Berthier, E.1
Warrick, J.2
Casavant, B.3
-
96
-
-
77954091833
-
Centrifugal microfluidics for biomedical applications
-
Gorkin, R. et al. Centrifugal microfluidics for biomedical applications. Lab Chip 10, 1758-1773 (2010).
-
(2010)
Lab Chip
, vol.10
, pp. 1758-1773
-
-
Gorkin, R.1
-
97
-
-
84872076487
-
Kit-On-A-Lid-Assays for accessible self-contained cell assays
-
Berthier, E. et al. Kit-On-A-Lid-Assays for accessible self-contained cell assays. Lab Chip 13, 424-431 (2013).
-
(2013)
Lab Chip
, vol.13
, pp. 424-431
-
-
Berthier, E.1
-
98
-
-
33746910186
-
Three options for citation tracking: Google Scholar, Scopus and Web of Science
-
doi:10.1186/ 1742-5581-3-7
-
Bakkalbasi, N., Bauer, K., Glover, J. & Wang, L. Three options for citation tracking: Google Scholar, Scopus and Web of Science. Biomed. Digit. Libr. doi:10.1186/ 1742-5581-3-7 (2006).
-
(2006)
Biomed. Digit. Libr
-
-
Bakkalbasi, N.1
Bauer, K.2
Glover, J.3
Wang, L.4
-
99
-
-
38949137710
-
Comparison of PubMed, Scopus, Web of Science, and Google Scholar: Strengths and weaknesses
-
Falagas, M. E., Pitsouni, E. I., Malietzis, G. A.& Pappas, G.Comparison of PubMed, Scopus, Web of Science, and Google Scholar: strengths and weaknesses. FASEB J. 22, 338-342 (2008).
-
(2008)
FASEB J.
, vol.22
, pp. 338-342
-
-
Falagas, M.E.1
Pitsouni, E.I.2
Malietzis, G.A.3
Pappas, G.4
-
100
-
-
84888361416
-
Crossing the endothelial barrier during metastasis
-
Reymond, N., Borda d'Água, B. & Ridley, A. J. et al. Crossing the endothelial barrier during metastasis. Nature Rev. Cancer 13, 858-870 (2013).
-
(2013)
Nature Rev. Cancer
, vol.13
, pp. 858-870
-
-
Reymond, N.1
Borda D'Água, B.2
Ridley, A.J.3
-
101
-
-
84866389468
-
Fabrication of biofunctionalized microfluidic structures by low-temperature wax bonding
-
Díaz-González, M. & Baldi, A. Fabrication of biofunctionalized microfluidic structures by low-temperature wax bonding. Anal. Chem. 84, 7838-7844 (2012).
-
(2012)
Anal. Chem.
, vol.84
, pp. 7838-7844
-
-
Díaz-González, M.1
Baldi, A.2
|