Oligonol suppresses lipid accumulation and improves insulin resistance in a palmitate-induced in HepG2 hepatocytes as a cellular steatosis model

BMC Complementary and Alternative Medicine

Volumn 15, Issue 1, 2015, Pages

  Park, Jae Yeo ^a   Kim, Younghwa ^b   Im, Jee Ae ^c   Lee, Hyangkyu ^a  

^a Yonsei University   (South Korea)

^b Department of Emergency Medical Technology Kyuongil University   (South Korea)

^c INTOTO Inc   (South Korea)

Author keywords

de novo fatty acid synthesis; Hepatic steatosis; Inflammation; Insulin resistance; Oligonol

Indexed keywords

CYTOKINE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; OLIGONOL; PALMITIC ACID; POLYPHENOL; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; UNCLASSIFIED DRUG; CATECHIN; PHENOL DERIVATIVE;

ARTICLE; CYTOKINE PRODUCTION; DOWN REGULATION; ENZYME PHOSPHORYLATION; FATTY ACID METABOLISM; FATTY LIVER; GENE EXPRESSION REGULATION; HEPG2 CELL LINE; HUMAN; HUMAN CELL; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID METABOLISM; LIPID STORAGE; LIPOGENESIS; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; BIOLOGICAL MODEL; DRUG EFFECTS; HEP-G2 CELL LINE; METABOLISM;

CATECHIN; FATTY LIVER; HEP G2 CELLS; HUMANS; INSULIN RESISTANCE; LIPID METABOLISM; MODELS, BIOLOGICAL; PHENOLS;

EID: 84934759679     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/s12906-015-0709-1     Document Type: Article

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