메뉴 건너뛰기




Volumn 22, Issue 1, 2015, Pages

The orphan nuclear receptor small heterodimer partner is required for thiazolidinedione effects in leptin-deficient mice

Author keywords

PPAR ; SHP; Thiazolidinedione; Troglitazone

Indexed keywords

ADIPOCYTOKINE; ADIPONECTIN; GLITAZONE DERIVATIVE; GLUCOSE; ORPHAN NUCLEAR RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 2; RESISTIN; SMALL HETERODIMER PARTNER; TRIACYLGLYCEROL; TROGLITAZONE; UNCLASSIFIED DRUG; 2,4 THIAZOLIDINEDIONE DERIVATIVE; 2,4-THIAZOLIDINEDIONE; BILE ACID; CELL RECEPTOR; INSULIN; LEPTIN; MESSENGER RNA; NUCLEAR RECEPTOR SUBFAMILY 0, GROUP B, MEMBER 2; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

EID: 84933519807     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1186/s12929-015-0133-3     Document Type: Article
Times cited : (7)

References (52)
  • 1
    • 0034611791 scopus 로고    scopus 로고
    • Obesity as a medical problem
    • 1:CAS:528:DC%2BD3cXis1Grtb8%3D 10766250
    • Kopelman PG. Obesity as a medical problem. Nature. 2000;404(6778):635-43.
    • (2000) Nature , vol.404 , Issue.6778 , pp. 635-643
    • Kopelman, P.G.1
  • 3
    • 84907990392 scopus 로고    scopus 로고
    • Thiazolidinediones and the promise of insulin sensitization in type 2 diabetes
    • 1:CAS:528:DC%2BC2cXhsFyrtbbN 25242225 doi:10.1016/j.cmet.2014.08.005
    • Soccio RE, Chen ER, Lazar MA. Thiazolidinediones and the promise of insulin sensitization in type 2 diabetes. Cell Metab. 2014;20(4):573-91. doi:10.1016/j.cmet.2014.08.005.
    • (2014) Cell Metab , vol.20 , Issue.4 , pp. 573-591
    • Soccio, R.E.1    Chen, E.R.2    Lazar, M.A.3
  • 4
    • 0029995670 scopus 로고    scopus 로고
    • Thiazolidinediones in the treatment of insulin resistance and type II diabetes
    • 1:CAS:528:DyaK28XntlCmtL4%3D 8922349
    • Saltiel AR, Olefsky JM. Thiazolidinediones in the treatment of insulin resistance and type II diabetes. Diabetes. 1996;45(12):1661-9.
    • (1996) Diabetes , vol.45 , Issue.12 , pp. 1661-1669
    • Saltiel, A.R.1    Olefsky, J.M.2
  • 5
    • 0033857387 scopus 로고    scopus 로고
    • Treatment of insulin resistance with peroxisome proliferator-activated receptor gamma agonists
    • 1:CAS:528:DC%2BD3cXlvFCltb8%3D 380259 10953021
    • Olefsky JM. Treatment of insulin resistance with peroxisome proliferator-activated receptor gamma agonists. J Clin Invest. 2000;106(4):467-72.
    • (2000) J Clin Invest , vol.106 , Issue.4 , pp. 467-472
    • Olefsky, J.M.1
  • 6
    • 0032005178 scopus 로고    scopus 로고
    • Metabolic effects of troglitazone monotherapy in type 2 diabetes mellitus. A randomized, double-blind, placebo-controlled trial
    • 1:CAS:528:DyaK1cXhtVahsL8%3D 9454525
    • Maggs DG, Buchanan TA, Burant CF, Cline G, Gumbiner B, Hsueh WA, et al. Metabolic effects of troglitazone monotherapy in type 2 diabetes mellitus. A randomized, double-blind, placebo-controlled trial. Ann Intern Med. 1998;128(3):176-85.
    • (1998) Ann Intern Med , vol.128 , Issue.3 , pp. 176-185
    • Maggs, D.G.1    Buchanan, T.A.2    Burant, C.F.3    Cline, G.4    Gumbiner, B.5    Hsueh, W.A.6
  • 7
    • 0025938575 scopus 로고
    • Characterization of CS-045, a new oral antidiabetic agent, II. Effects on glycemic control and pancreatic islet structure at a late stage of the diabetic syndrome in C57BL/KsJ-db/db mice
    • 1:CAS:528:DyaK3MXmt1ehsrY%3D 1943750
    • Fujiwara T, Wada M, Fukuda K, Fukami M, Yoshioka S, Yoshioka T, et al. Characterization of CS-045, a new oral antidiabetic agent, II. Effects on glycemic control and pancreatic islet structure at a late stage of the diabetic syndrome in C57BL/KsJ-db/db mice. Metabolism. 1991;40(11):1213-8.
    • (1991) Metabolism , vol.40 , Issue.11 , pp. 1213-1218
    • Fujiwara, T.1    Wada, M.2    Fukuda, K.3    Fukami, M.4    Yoshioka, S.5    Yoshioka, T.6
  • 8
    • 0024160854 scopus 로고
    • Characterization of new oral antidiabetic agent CS-045. Studies in KK and ob/ob mice and Zucker fatty rats
    • 1:CAS:528:DyaL1MXjtlGrsw%3D%3D 3053303
    • Fujiwara T, Yoshioka S, Yoshioka T, Ushiyama I, Horikoshi H. Characterization of new oral antidiabetic agent CS-045. Studies in KK and ob/ob mice and Zucker fatty rats. Diabetes. 1988;37(11):1549-58.
    • (1988) Diabetes , vol.37 , Issue.11 , pp. 1549-1558
    • Fujiwara, T.1    Yoshioka, S.2    Yoshioka, T.3    Ushiyama, I.4    Horikoshi, H.5
  • 9
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)
    • 1:CAS:528:DyaK2MXmtV2itr0%3D 7768881
    • Lehmann JM, Moore LB, Smith-Oliver TA, Wilkison WO, Willson TM, Kliewer SA. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma). J Biol Chem. 1995;270(22):12953-6.
    • (1995) J Biol Chem , vol.270 , Issue.22 , pp. 12953-12956
    • Lehmann, J.M.1    Moore, L.B.2    Smith-Oliver, T.A.3    Wilkison, W.O.4    Willson, T.M.5    Kliewer, S.A.6
  • 10
    • 2542491213 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma in diabetes and metabolism
    • 1:CAS:528:DC%2BD2cXksVelsLk%3D 15165749
    • Rangwala SM, Lazar MA. Peroxisome proliferator-activated receptor gamma in diabetes and metabolism. Trends Pharmacol Sci. 2004;25(6):331-6.
    • (2004) Trends Pharmacol Sci , vol.25 , Issue.6 , pp. 331-336
    • Rangwala, S.M.1    Lazar, M.A.2
  • 11
    • 0028641559 scopus 로고
    • Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid- activated transcription factor
    • 1:STN:280:DyaK2M%2FpsVaqsg%3D%3D 8001151
    • Tontonoz P, Hu E, Spiegelman BM. Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid- activated transcription factor. Cell. 1994;79(7):1147-56.
    • (1994) Cell , vol.79 , Issue.7 , pp. 1147-1156
    • Tontonoz, P.1    Hu, E.2    Spiegelman, B.M.3
  • 12
    • 18644384149 scopus 로고    scopus 로고
    • Genetic analysis of adipogenesis through peroxisome proliferator-activated receptor gamma isoforms
    • 1:CAS:528:DC%2BD38XotF2gsbc%3D 12200443
    • Mueller E, Drori S, Aiyer A, Yie J, Sarraf P, Chen H, et al. Genetic analysis of adipogenesis through peroxisome proliferator-activated receptor gamma isoforms. J Biol Chem. 2002;277(44):41925-30.
    • (2002) J Biol Chem , vol.277 , Issue.44 , pp. 41925-41930
    • Mueller, E.1    Drori, S.2    Aiyer, A.3    Yie, J.4    Sarraf, P.5    Chen, H.6
  • 13
    • 0030977450 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids
    • 1:CAS:528:DyaK2sXjsVGqtro%3D 508081 9153284
    • Vidal-Puig AJ, Considine RV, Jimenez-Linan M, Werman A, Pories WJ, Caro JF, et al. Peroxisome proliferator-activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids. J Clin Invest. 1997;99(10):2416-22.
    • (1997) J Clin Invest , vol.99 , Issue.10 , pp. 2416-2422
    • Vidal-Puig, A.J.1    Considine, R.V.2    Jimenez-Linan, M.3    Werman, A.4    Pories, W.J.5    Caro, J.F.6
  • 14
    • 3242720242 scopus 로고    scopus 로고
    • Selective disruption of PPARgamma 2 impairs the development of adipose tissue and insulin sensitivity
    • 1:CAS:528:DC%2BD2cXmtFWmtrY%3D 489998 15249658
    • Zhang J, Fu M, Cui T, Xiong C, Xu K, Zhong W, et al. Selective disruption of PPARgamma 2 impairs the development of adipose tissue and insulin sensitivity. Proc Natl Acad Sci U S A. 2004;101(29):10703-8.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.29 , pp. 10703-10708
    • Zhang, J.1    Fu, M.2    Cui, T.3    Xiong, C.4    Xu, K.5    Zhong, W.6
  • 15
    • 85047693638 scopus 로고    scopus 로고
    • Muscle-specific PPARgamma-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones
    • 1:CAS:528:DC%2BD3sXms1Wnurg%3D 171387 12925701
    • Norris AW, Chen L, Fisher SJ, Szanto I, Ristow M, Jozsi AC, et al. Muscle-specific PPARgamma-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones. J Clin Invest. 2003;112(4):608-18.
    • (2003) J Clin Invest , vol.112 , Issue.4 , pp. 608-618
    • Norris, A.W.1    Chen, L.2    Fisher, S.J.3    Szanto, I.4    Ristow, M.5    Jozsi, A.C.6
  • 16
    • 9144229185 scopus 로고    scopus 로고
    • Adipose-specific peroxisome proliferator-activated receptor gamma knockout causes insulin resistance in fat and liver but not in muscle
    • 1:CAS:528:DC%2BD2cXhtVCnsA%3D%3D 307633 14660788
    • He W, Barak Y, Hevener A, Olson P, Liao D, Le J, et al. Adipose-specific peroxisome proliferator-activated receptor gamma knockout causes insulin resistance in fat and liver but not in muscle. Proc Natl Acad Sci U S A. 2003;100(26):15712-7.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.26 , pp. 15712-15717
    • He, W.1    Barak, Y.2    Hevener, A.3    Olson, P.4    Liao, D.5    Le, J.6
  • 17
    • 34249907880 scopus 로고    scopus 로고
    • Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones
    • 1:CAS:528:DC%2BD2sXmsVWku7w%3D 1868788 17525798
    • Hevener AL, Olefsky JM, Reichart D, Nguyen MT, Bandyopadyhay G, Leung HY, et al. Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones. J Clin Invest. 2007;117(6):1658-69.
    • (2007) J Clin Invest , vol.117 , Issue.6 , pp. 1658-1669
    • Hevener, A.L.1    Olefsky, J.M.2    Reichart, D.3    Nguyen, M.T.4    Bandyopadyhay, G.5    Leung, H.Y.6
  • 18
    • 0037373008 scopus 로고    scopus 로고
    • Liver-specific disruption of PPARgamma in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes
    • 1:CAS:528:DC%2BD3sXhvFenurY%3D 151902 12618528
    • Matsusue K, Haluzik M, Lambert G, Yim SH, Gavrilova O, Ward JM, et al. Liver-specific disruption of PPARgamma in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes. J Clin Invest. 2003;111(5):737-47.
    • (2003) J Clin Invest , vol.111 , Issue.5 , pp. 737-747
    • Matsusue, K.1    Haluzik, M.2    Lambert, G.3    Yim, S.H.4    Gavrilova, O.5    Ward, J.M.6
  • 19
    • 0033708410 scopus 로고    scopus 로고
    • Adipose tissue is required for the antidiabetic, but not for the hypolipidemic, effect of thiazolidinediones
    • 1:CAS:528:DC%2BD3cXotlChu74%3D 381440 11086023
    • Chao L, Marcus-Samuels B, Mason MM, Moitra J, Vinson C, Arioglu E, et al. Adipose tissue is required for the antidiabetic, but not for the hypolipidemic, effect of thiazolidinediones. J Clin Invest. 2000;106(10):1221-8.
    • (2000) J Clin Invest , vol.106 , Issue.10 , pp. 1221-1228
    • Chao, L.1    Marcus-Samuels, B.2    Mason, M.M.3    Moitra, J.4    Vinson, C.5    Arioglu, E.6
  • 20
    • 0033695790 scopus 로고    scopus 로고
    • Up-regulation of peroxisome proliferator-activated receptors (PPAR-alpha) and PPAR-gamma messenger ribonucleic acid expression in the liver in murine obesity: Troglitazone induces expression of PPAR-gamma-responsive adipose tissue-specific genes in the liver of obese diabetic mice
    • 1:CAS:528:DC%2BD3cXnslKhurw%3D 11089532
    • Memon RA, Tecott LH, Nonogaki K, Beigneux A, Moser AH, Grunfeld C, et al. Up-regulation of peroxisome proliferator-activated receptors (PPAR-alpha) and PPAR-gamma messenger ribonucleic acid expression in the liver in murine obesity: troglitazone induces expression of PPAR-gamma-responsive adipose tissue-specific genes in the liver of obese diabetic mice. Endocrinology. 2000;141(11):4021-31.
    • (2000) Endocrinology , vol.141 , Issue.11 , pp. 4021-4031
    • Memon, R.A.1    Tecott, L.H.2    Nonogaki, K.3    Beigneux, A.4    Moser, A.H.5    Grunfeld, C.6
  • 21
    • 35748972366 scopus 로고    scopus 로고
    • Genes involved in fatty acid partitioning and binding, lipolysis, monocyte/macrophage recruitment, and inflammation are overexpressed in the human fatty liver of insulin-resistant subjects
    • 1:CAS:528:DC%2BD2sXhtlWitLzP 17704301
    • Westerbacka J, Kolak M, Kiviluoto T, Arkkila P, Siren J, Hamsten A, et al. Genes involved in fatty acid partitioning and binding, lipolysis, monocyte/macrophage recruitment, and inflammation are overexpressed in the human fatty liver of insulin-resistant subjects. Diabetes. 2007;56(11):2759-65.
    • (2007) Diabetes , vol.56 , Issue.11 , pp. 2759-2765
    • Westerbacka, J.1    Kolak, M.2    Kiviluoto, T.3    Arkkila, P.4    Siren, J.5    Hamsten, A.6
  • 22
    • 0141532275 scopus 로고    scopus 로고
    • Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-gamma ligand rosiglitazone
    • 1:CAS:528:DC%2BD3sXovFGhurc%3D 14512888
    • Neuschwander-Tetri BA, Brunt EM, Wehmeier KR, Oliver D, Bacon BR. Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-gamma ligand rosiglitazone. Hepatology. 2003;38(4):1008-17.
    • (2003) Hepatology , vol.38 , Issue.4 , pp. 1008-1017
    • Neuschwander-Tetri, B.A.1    Brunt, E.M.2    Wehmeier, K.R.3    Oliver, D.4    Bacon, B.R.5
  • 23
    • 33751545838 scopus 로고    scopus 로고
    • A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis
    • 1:CAS:528:DC%2BD28Xht1OrtrvI 17135584
    • Belfort R, Harrison SA, Brown K, Darland C, Finch J, Hardies J, et al. A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis. N Engl J Med. 2006;355(22):2297-307.
    • (2006) N Engl J Med , vol.355 , Issue.22 , pp. 2297-2307
    • Belfort, R.1    Harrison, S.A.2    Brown, K.3    Darland, C.4    Finch, J.5    Hardies, J.6
  • 24
    • 0035895268 scopus 로고    scopus 로고
    • Mutations in the small heterodimer partner gene are associated with mild obesity in Japanese subjects
    • 1:CAS:528:DC%2BD3MXnslKgtQ%3D%3D 14629 11136233
    • Nishigori H, Tomura H, Tonooka N, Kanamori M, Yamada S, Sho K, et al. Mutations in the small heterodimer partner gene are associated with mild obesity in Japanese subjects. Proc Natl Acad Sci U S A. 2001;98(2):575-80.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.2 , pp. 575-580
    • Nishigori, H.1    Tomura, H.2    Tonooka, N.3    Kanamori, M.4    Yamada, S.5    Sho, K.6
  • 25
    • 0037407646 scopus 로고    scopus 로고
    • Genetic variation in the small heterodimer partner gene and young-onset type 2 diabetes, obesity, and birth weight in U.K. subjects
    • 1:CAS:528:DC%2BD3sXjsFGhu70%3D 12716764
    • Mitchell SM, Weedon MN, Owen KR, Shields B, Wilkins-Wall B, Walker M, et al. Genetic variation in the small heterodimer partner gene and young-onset type 2 diabetes, obesity, and birth weight in U.K. subjects. Diabetes. 2003;52(5):1276-9.
    • (2003) Diabetes , vol.52 , Issue.5 , pp. 1276-1279
    • Mitchell, S.M.1    Weedon, M.N.2    Owen, K.R.3    Shields, B.4    Wilkins-Wall, B.5    Walker, M.6
  • 26
    • 12444293733 scopus 로고    scopus 로고
    • Contribution of variants in the small heterodimer partner gene to birthweight, adiposity, and insulin levels: Mutational analysis and association studies in multiple populations
    • 1:CAS:528:DC%2BD3sXjsFGhu7g%3D 12716767
    • Hung CC, Farooqi IS, Ong K, Luan J, Keogh JM, Pembrey M, et al. Contribution of variants in the small heterodimer partner gene to birthweight, adiposity, and insulin levels: mutational analysis and association studies in multiple populations. Diabetes. 2003;52(5):1288-91.
    • (2003) Diabetes , vol.52 , Issue.5 , pp. 1288-1291
    • Hung, C.C.1    Farooqi, I.S.2    Ong, K.3    Luan, J.4    Keogh, J.M.5    Pembrey, M.6
  • 27
    • 55549142230 scopus 로고    scopus 로고
    • Mutations in the small heterodimer partner gene increase morbidity risk in Japanese type 2 diabetes patients
    • 18781616 doi:10.1002/humu.20865
    • Enya M, Horikawa Y, Kuroda E, Yonemaru K, Tonooka N, Tomura H, et al. Mutations in the small heterodimer partner gene increase morbidity risk in Japanese type 2 diabetes patients. Hum Mutat. 2008;29(11):E271-7. doi:10.1002/humu.20865.
    • (2008) Hum Mutat , vol.29 , Issue.11 , pp. E271-E277
    • Enya, M.1    Horikawa, Y.2    Kuroda, E.3    Yonemaru, K.4    Tonooka, N.5    Tomura, H.6
  • 28
    • 0030001371 scopus 로고    scopus 로고
    • An orphan nuclear hormone receptor that lacks a DNA binding domain and heterodimerizes with other receptors
    • 1:CAS:528:DyaK28Xjt1Okurg%3D 8650544
    • Seol W, Choi HS, Moore DD. An orphan nuclear hormone receptor that lacks a DNA binding domain and heterodimerizes with other receptors. Science. 1996;272(5266):1336-9.
    • (1996) Science , vol.272 , Issue.5266 , pp. 1336-1339
    • Seol, W.1    Choi, H.S.2    Moore, D.D.3
  • 29
    • 0030712244 scopus 로고    scopus 로고
    • Novel receptor interaction and repression domains in the orphan receptor SHP
    • 1:CAS:528:DyaK2sXnsFWgs7s%3D 232569 9372944
    • Seol W, Chung M, Moore DD. Novel receptor interaction and repression domains in the orphan receptor SHP. Mol Cell Biol. 1997;17(12):7126-31.
    • (1997) Mol Cell Biol , vol.17 , Issue.12 , pp. 7126-7131
    • Seol, W.1    Chung, M.2    Moore, D.D.3
  • 30
    • 0032951135 scopus 로고    scopus 로고
    • The orphan nuclear receptor SHP inhibits agonist-dependent transcriptional activity of estrogen receptors ERalpha and ERbeta
    • 1:CAS:528:DyaK1MXjvVWrsA%3D%3D 9867849
    • Johansson L, Thomsen JS, Damdimopoulos AE, Spyrou G, Gustafsson J, Treuter E. The orphan nuclear receptor SHP inhibits agonist-dependent transcriptional activity of estrogen receptors ERalpha and ERbeta. J Biol Chem. 1999;274(1):345-53.
    • (1999) J Biol Chem , vol.274 , Issue.1 , pp. 345-353
    • Johansson, L.1    Thomsen, J.S.2    Damdimopoulos, A.E.3    Spyrou, G.4    Gustafsson, J.5    Treuter, E.6
  • 31
    • 0033986961 scopus 로고    scopus 로고
    • The orphan nuclear receptor SHP inhibits hepatocyte nuclear factor 4 and retinoid X receptor transactivation: Two mechanisms for repression
    • 1:CAS:528:DC%2BD3cXlt1Sl 85074 10594021
    • Lee YK, Dell H, Dowhan DH, Hadzopoulou-Cladaras M, Moore DD. The orphan nuclear receptor SHP inhibits hepatocyte nuclear factor 4 and retinoid X receptor transactivation: two mechanisms for repression. Mol Cell Biol. 2000;20(1):187-95.
    • (2000) Mol Cell Biol , vol.20 , Issue.1 , pp. 187-195
    • Lee, Y.K.1    Dell, H.2    Dowhan, D.H.3    Hadzopoulou-Cladaras, M.4    Moore, D.D.5
  • 32
    • 0037169541 scopus 로고    scopus 로고
    • Dual mechanisms for repression of the monomeric orphan receptor liver receptor homologous protein-1 by the orphan small heterodimer partner
    • 1:CAS:528:DC%2BD38XhtVSgsr0%3D 11668176
    • Lee YK, Moore DD. Dual mechanisms for repression of the monomeric orphan receptor liver receptor homologous protein-1 by the orphan small heterodimer partner. J Biol Chem. 2002;277(4):2463-7.
    • (2002) J Biol Chem , vol.277 , Issue.4 , pp. 2463-2467
    • Lee, Y.K.1    Moore, D.D.2
  • 33
    • 0037059762 scopus 로고    scopus 로고
    • Small heterodimer partner, an orphan nuclear receptor, augments peroxisome proliferator-activated receptor gamma transactivation
    • 1:CAS:528:DC%2BD38XnvFyitg%3D%3D 11696534
    • Nishizawa H, Yamagata K, Shimomura I, Takahashi M, Kuriyama H, Kishida K, et al. Small heterodimer partner, an orphan nuclear receptor, augments peroxisome proliferator-activated receptor gamma transactivation. J Biol Chem. 2002;277(2):1586-92.
    • (2002) J Biol Chem , vol.277 , Issue.2 , pp. 1586-1592
    • Nishizawa, H.1    Yamagata, K.2    Shimomura, I.3    Takahashi, M.4    Kuriyama, H.5    Kishida, K.6
  • 34
    • 23044502910 scopus 로고    scopus 로고
    • Regulation of hepatic metabolic pathways by the orphan nuclear receptor SHP
    • 1:CAS:528:DC%2BD2MXmt1ynu7w%3D 1176456 15973435
    • Boulias K, Katrakili N, Bamberg K, Underhill P, Greenfield A, Talianidis I. Regulation of hepatic metabolic pathways by the orphan nuclear receptor SHP. Embo J. 2005;24(14):2624-33.
    • (2005) Embo J , vol.24 , Issue.14 , pp. 2624-2633
    • Boulias, K.1    Katrakili, N.2    Bamberg, K.3    Underhill, P.4    Greenfield, A.5    Talianidis, I.6
  • 36
    • 34547411540 scopus 로고    scopus 로고
    • Molecular characterization of the role of orphan receptor small heterodimer partner in development of fatty liver
    • 1:CAS:528:DC%2BD2sXosVylt7k%3D 17526026
    • Huang J, Iqbal J, Saha PK, Liu J, Chan L, Hussain MM, et al. Molecular characterization of the role of orphan receptor small heterodimer partner in development of fatty liver. Hepatology. 2007;46(1):147-57.
    • (2007) Hepatology , vol.46 , Issue.1 , pp. 147-157
    • Huang, J.1    Iqbal, J.2    Saha, P.K.3    Liu, J.4    Chan, L.5    Hussain, M.M.6
  • 37
    • 33744781581 scopus 로고    scopus 로고
    • Liver-specific deletion of acetyl-CoA carboxylase 1 reduces hepatic triglyceride accumulation without affecting glucose homeostasis
    • 1:CAS:528:DC%2BD28XlvFChur0%3D 1570106 16717184
    • Mao J, DeMayo FJ, Li H, Abu-Elheiga L, Gu Z, Shaikenov TE, et al. Liver-specific deletion of acetyl-CoA carboxylase 1 reduces hepatic triglyceride accumulation without affecting glucose homeostasis. Proc Natl Acad Sci U S A. 2006;103(22):8552-7.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , Issue.22 , pp. 8552-8557
    • Mao, J.1    DeMayo, F.J.2    Li, H.3    Abu-Elheiga, L.4    Gu, Z.5    Shaikenov, T.E.6
  • 38
    • 27844551588 scopus 로고    scopus 로고
    • The orphan nuclear receptor SHP regulates PGC-1alpha expression and energy production in brown adipocytes
    • 1:CAS:528:DC%2BD2MXhtFGktrjN 16213225
    • Wang L, Liu J, Saha P, Huang J, Chan L, Spiegelman B, et al. The orphan nuclear receptor SHP regulates PGC-1alpha expression and energy production in brown adipocytes. Cell Metab. 2005;2(4):227-38.
    • (2005) Cell Metab , vol.2 , Issue.4 , pp. 227-238
    • Wang, L.1    Liu, J.2    Saha, P.3    Huang, J.4    Chan, L.5    Spiegelman, B.6
  • 39
    • 81855217508 scopus 로고    scopus 로고
    • Dissociation of diabetes and obesity in mice lacking orphan nuclear receptor small heterodimer partner
    • 1:CAS:528:DC%2BC3MXhsFaktL3F 3220290 21949050 doi:10.1194/jlr.M016048
    • Park YJ, Kim SC, Kim J, Anakk S, Lee JM, Tseng HT, et al. Dissociation of diabetes and obesity in mice lacking orphan nuclear receptor small heterodimer partner. J Lipid Res. 2011;52(12):2234-44. doi:10.1194/jlr.M016048.
    • (2011) J Lipid Res , vol.52 , Issue.12 , pp. 2234-2244
    • Park, Y.J.1    Kim, S.C.2    Kim, J.3    Anakk, S.4    Lee, J.M.5    Tseng, H.T.6
  • 40
    • 19944426990 scopus 로고    scopus 로고
    • Overexpression of short heterodimer partner recovers impaired glucose-stimulated insulin secretion of pancreatic beta-cells overexpressing UCP2
    • 1:CAS:528:DC%2BD2cXptlCqsb8%3D 15525581
    • Suh YH, Kim SY, Lee HY, Jang BC, Bae JH, Sohn JN, et al. Overexpression of short heterodimer partner recovers impaired glucose-stimulated insulin secretion of pancreatic beta-cells overexpressing UCP2. J Endocrinol. 2004;183(1):133-44.
    • (2004) J Endocrinol , vol.183 , Issue.1 , pp. 133-144
    • Suh, Y.H.1    Kim, S.Y.2    Lee, H.Y.3    Jang, B.C.4    Bae, J.H.5    Sohn, J.N.6
  • 41
    • 0032587268 scopus 로고    scopus 로고
    • Rosiglitazone (BRL49653), a PPARgamma-selective agonist, causes peroxisome proliferator-like liver effects in obese mice
    • 1:CAS:528:DyaK1MXksVKitbk%3D 10393202
    • Edvardsson U, Bergstrom M, Alexandersson M, Bamberg K, Ljung B, Dahllof B. Rosiglitazone (BRL49653), a PPARgamma-selective agonist, causes peroxisome proliferator-like liver effects in obese mice. J Lipid Res. 1999;40(7):1177-84.
    • (1999) J Lipid Res , vol.40 , Issue.7 , pp. 1177-1184
    • Edvardsson, U.1    Bergstrom, M.2    Alexandersson, M.3    Bamberg, K.4    Ljung, B.5    Dahllof, B.6
  • 42
    • 33646852805 scopus 로고    scopus 로고
    • Pioglitazone ameliorates insulin resistance and diabetes by both adiponectin-dependent and -independent pathways
    • 1:CAS:528:DC%2BD28XivVCns7s%3D 16431926
    • Kubota N, Terauchi Y, Kubota T, Kumagai H, Itoh S, Satoh H, et al. Pioglitazone ameliorates insulin resistance and diabetes by both adiponectin-dependent and -independent pathways. J Biol Chem. 2006;281(13):8748-55.
    • (2006) J Biol Chem , vol.281 , Issue.13 , pp. 8748-8755
    • Kubota, N.1    Terauchi, Y.2    Kubota, T.3    Kumagai, H.4    Itoh, S.5    Satoh, H.6
  • 43
    • 0034806965 scopus 로고    scopus 로고
    • Differential regulation of adipocytokine mRNAs by rosiglitazone in db/db mice
    • 1:CAS:528:DC%2BD3MXmtFyqs78%3D 11520059
    • Moore GB, Chapman H, Holder JC, Lister CA, Piercy V, Smith SA, et al. Differential regulation of adipocytokine mRNAs by rosiglitazone in db/db mice. Biochem Biophys Res Commun. 2001;286(4):735-41.
    • (2001) Biochem Biophys Res Commun , vol.286 , Issue.4 , pp. 735-741
    • Moore, G.B.1    Chapman, H.2    Holder, J.C.3    Lister, C.A.4    Piercy, V.5    Smith, S.A.6
  • 45
    • 0242641149 scopus 로고    scopus 로고
    • Adipose tissue resistin expression is severely suppressed in obesity and stimulated by peroxisome proliferator-activated receptor gamma agonists
    • 1:CAS:528:DC%2BD3MXlsVKgt78%3D 11373275
    • Way JM, Gorgun CZ, Tong Q, Uysal KT, Brown KK, Harrington WW, et al. Adipose tissue resistin expression is severely suppressed in obesity and stimulated by peroxisome proliferator-activated receptor gamma agonists. J Biol Chem. 2001;276(28):25651-3.
    • (2001) J Biol Chem , vol.276 , Issue.28 , pp. 25651-25653
    • Way, J.M.1    Gorgun, C.Z.2    Tong, Q.3    Uysal, K.T.4    Brown, K.K.5    Harrington, W.W.6
  • 46
    • 3042784523 scopus 로고    scopus 로고
    • Regulation of resistin expression and circulating levels in obesity, diabetes, and fasting
    • 1:CAS:528:DC%2BD2cXlslWgtrc%3D 15220189
    • Rajala MW, Qi Y, Patel HR, Takahashi N, Banerjee R, Pajvani UB, et al. Regulation of resistin expression and circulating levels in obesity, diabetes, and fasting. Diabetes. 2004;53(7):1671-9.
    • (2004) Diabetes , vol.53 , Issue.7 , pp. 1671-1679
    • Rajala, M.W.1    Qi, Y.2    Patel, H.R.3    Takahashi, N.4    Banerjee, R.5    Pajvani, U.B.6
  • 47
    • 0141446024 scopus 로고    scopus 로고
    • Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass
    • 1:CAS:528:DC%2BD3sXmvVCqsLw%3D 12805374
    • Gavrilova O, Haluzik M, Matsusue K, Cutson JJ, Johnson L, Dietz KR, et al. Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass. J Biol Chem. 2003;278(36):34268-76.
    • (2003) J Biol Chem , vol.278 , Issue.36 , pp. 34268-34276
    • Gavrilova, O.1    Haluzik, M.2    Matsusue, K.3    Cutson, J.J.4    Johnson, L.5    Dietz, K.R.6
  • 48
    • 33845984572 scopus 로고    scopus 로고
    • Aberrant hepatic expression of PPARgamma2 stimulates hepatic lipogenesis in a mouse model of obesity, insulin resistance, dyslipidemia, and hepatic steatosis
    • 1:CAS:528:DC%2BD28Xht1KitrbO 16971390
    • Zhang YL, Hernandez-Ono A, Siri P, Weisberg S, Conlon D, Graham MJ, et al. Aberrant hepatic expression of PPARgamma2 stimulates hepatic lipogenesis in a mouse model of obesity, insulin resistance, dyslipidemia, and hepatic steatosis. J Biol Chem. 2006;281(49):37603-15.
    • (2006) J Biol Chem , vol.281 , Issue.49 , pp. 37603-37615
    • Zhang, Y.L.1    Hernandez-Ono, A.2    Siri, P.3    Weisberg, S.4    Conlon, D.5    Graham, M.J.6
  • 49
    • 19444383246 scopus 로고    scopus 로고
    • PPARgamma2 regulates lipogenesis and lipid accumulation in steatotic hepatocytes
    • 1:CAS:528:DC%2BD2MXlsVylsLo%3D 15644454
    • Schadinger SE, Bucher NL, Schreiber BM, Farmer SR. PPARgamma2 regulates lipogenesis and lipid accumulation in steatotic hepatocytes. Am J Physiol Endocrinol Metab. 2005;288(6):E1195-205.
    • (2005) Am J Physiol Endocrinol Metab , vol.288 , Issue.6 , pp. E1195-E1205
    • Schadinger, S.E.1    Bucher, N.L.2    Schreiber, B.M.3    Farmer, S.R.4
  • 50
    • 0346003777 scopus 로고    scopus 로고
    • Adipocyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor gamma1 (PPARgamma1) overexpression
    • 1:CAS:528:DC%2BD38XpvVWgu7g%3D 12401792
    • Yu S, Matsusue K, Kashireddy P, Cao WQ, Yeldandi V, Yeldandi AV, et al. Adipocyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor gamma1 (PPARgamma1) overexpression. J Biol Chem. 2003;278(1):498-505.
    • (2003) J Biol Chem , vol.278 , Issue.1 , pp. 498-505
    • Yu, S.1    Matsusue, K.2    Kashireddy, P.3    Cao, W.Q.4    Yeldandi, V.5    Yeldandi, A.V.6
  • 51
    • 79956197013 scopus 로고    scopus 로고
    • SHP-dependent and -independent induction of peroxisome proliferator-activated receptor-gamma by the bile acid sensor farnesoid X receptor counter-regulates the pro-inflammatory phenotype of liver myofibroblasts
    • 1:CAS:528:DC%2BC3MXmtVyqsbw%3D 21279417 doi:10.1007/s00011-010-0306-1
    • Renga B, Mencarelli A, Migliorati M, Cipriani S, D'Amore C, Distrutti E, et al. SHP-dependent and -independent induction of peroxisome proliferator-activated receptor-gamma by the bile acid sensor farnesoid X receptor counter-regulates the pro-inflammatory phenotype of liver myofibroblasts. Inflamm Res. 2011;60(6):577-87. doi:10.1007/s00011-010-0306-1.
    • (2011) Inflamm Res , vol.60 , Issue.6 , pp. 577-587
    • Renga, B.1    Mencarelli, A.2    Migliorati, M.3    Cipriani, S.4    D'Amore, C.5    Distrutti, E.6
  • 52
    • 84899480621 scopus 로고    scopus 로고
    • All-trans-retinoic acid ameliorates hepatic steatosis in mice by a novel transcriptional cascade
    • 1:CAS:528:DC%2BC2cXntFCmu7Y%3D 4008145 24038081 doi:10.1002/hep.26699
    • Kim SC, Kim CK, Axe D, Cook A, Lee M, Li T, et al. All-trans-retinoic acid ameliorates hepatic steatosis in mice by a novel transcriptional cascade. Hepatology. 2014;59(5):1750-60. doi:10.1002/hep.26699.
    • (2014) Hepatology , vol.59 , Issue.5 , pp. 1750-1760
    • Kim, S.C.1    Kim, C.K.2    Axe, D.3    Cook, A.4    Lee, M.5    Li, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.