Pioglitazone ameliorates insulin resistance and diabetes by both adiponectin-dependent and -independent pathways

Journal of Biological Chemistry

Volumn 281, Issue 13, 2006, Pages 8748-8755

  Kubota, Naoto ^a,b,c   Terauchi, Yasuo ^a,b   Kubota, Tetsuya ^a,c   Kumagai, Hiroki ^a   Itoh, Shinsuke ^a   Satoh, Hidemi ^a   Yano, Wataru ^a   Ogata, Hitomi ^d   Tokuyama, Kumpei ^d   Takamoto, Iseki ^a,b,c   Mineyama, Tomoka ^a   Ishikawa, Michiro ^e   Moroi, Masao ^e   Sugi, Kaoru ^e   Yamauchi, Toshimasa ^a,b   Ueki, Kohjiro ^a   Tobe, Kazuyuki ^a,b   Noda, Tetsuo ^f,g   Nagai, Ryozo ^a   Kadowaki, Takashi ^a,b,c  

^a UNIVERSITY OF TOKYO   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c NATIONAL INSTITUTE OF HEALTH AND NUTRITION   (Japan)

^d UNIVERSITY OF TSUKUBA   (Japan)

^e TOHO UNIVERSITY OHASHI MEDICAL CENTER   (Japan)

^f CANCER CHEMOTHERAPY CENTER   (Japan)

^g TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; DISEASES; FATTY ACIDS; MUSCULOSKELETAL SYSTEM; PLASMAS; TISSUE;

AMELIORATION; OBESITY; PLASMA ADIPONECTIN LEVELS; THIAZOLIDINEDIONES;

INSULIN;

2,4 THIAZOLIDINEDIONE DERIVATIVE; ADIPONECTIN; FATTY ACID; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PIOGLITAZONE; RESISTIN; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; ANTIDIABETIC AGENT; INSULIN;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; DIABETES MELLITUS; DRUG EFFECT; DRUG MECHANISM; FATTY ACID BLOOD LEVEL; GLUCONEOGENESIS; GLUCOSE TRANSPORT; INSULIN RESISTANCE; LIVER; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; TREATMENT DURATION; TRIACYLGLYCEROL BLOOD LEVEL; UPREGULATION; ANIMAL; BIOSYNTHESIS; BLOOD; C57BL MOUSE; CROSS BREEDING; DIET RESTRICTION; DOSE RESPONSE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENETICS; GLUCOSE BLOOD LEVEL; GLUCOSE CLAMP TECHNIQUE; GLUCOSE TOLERANCE TEST; MALE; METABOLISM; MOUSE MUTANT; TIME; WESTERN BLOTTING;

ADIPONECTIN; ANIMALS; BLOOD GLUCOSE; BLOTTING, WESTERN; CROSSES, GENETIC; DIABETES MELLITUS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; FASTING; FATTY ACIDS, NONESTERIFIED; FEMALE; GLUCOSE; GLUCOSE CLAMP TECHNIQUE; GLUCOSE TOLERANCE TEST; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN RESISTANCE; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE, SKELETAL; THIAZOLIDINEDIONES; TIME FACTORS; TRIGLYCERIDES;

EID: 33646852805     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M505649200     Document Type: Article

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