Impact of suppressing retinoic acid-related orphan receptor gamma t (ROR)γt in ameliorating central nervous system autoimmunity

Clinical and Experimental Immunology

Volumn 179, Issue 1, 2015, Pages 108-118

  Yang, Y ^a   Winger, R C ^a,c   Lee, P W ^b   Nuro Gyina, P K ^b   Minc, A ^b   Larson, M ^a   Liu, Y ^a   Pei, W ^a   Rieser, E ^b   Racke, M K ^a   Lovett Racke, A E ^a  

^a THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c NORTHWESTERN UNIVERSITY   (United States)

Author keywords

EAE; Multiple sclerosis; ROR t; T cell encephalitogenicity; Transcription factor

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 17; RETINOID RELATED ORPHAN RECEPTOR GAMMA; SMALL INTERFERING RNA; INTERLEUKIN 23;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOIMMUNITY; CD4+ T LYMPHOCYTE; CELL POPULATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; ENZYME INHIBITION; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; MOUSE; NONHUMAN; PATHOGENICITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE; ANIMAL; BIOSYNTHESIS; DISEASE MODEL; DRUG EFFECTS; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; MULTIPLE SCLEROSIS; MYELIN SHEATH; RNA INTERFERENCE;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CENTRAL NERVOUS SYSTEM; DISEASE MODELS, ANIMAL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; GENE EXPRESSION; GENE EXPRESSION REGULATION; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; INTERLEUKIN-23; MICE; MICE, KNOCKOUT; MULTIPLE SCLEROSIS; MYELIN SHEATH; NUCLEAR RECEPTOR SUBFAMILY 1, GROUP F, MEMBER 3; RNA INTERFERENCE;

EID: 84933509275     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/cei.12441     Document Type: Article

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