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Volumn 172, Issue 14, 2015, Pages 3484-3494

Eugenol dilates mesenteric arteries and reduces systemic BP by activating endothelial cell TRPV4 channels

Author keywords

[No Author keywords available]

Indexed keywords

EUGENOL; INDOMETACIN; INTERMEDIATE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; SMALL INTERFERING RNA; VANILLOID RECEPTOR 4; TRPV4 PROTEIN, MOUSE; VANILLOID RECEPTOR;

EID: 84933042439     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.13156     Document Type: Article
Times cited : (51)

References (65)
  • 5
    • 84865424248 scopus 로고    scopus 로고
    • Mechanisms underlining gender differences in Phenylephrine contraction of normoglycaemic and short-term Streptozotocin-induced diabetic WKY rat aorta
    • Aloysius UI, Achike FI, Mustafa MR, (2012). Mechanisms underlining gender differences in Phenylephrine contraction of normoglycaemic and short-term Streptozotocin-induced diabetic WKY rat aorta. Vascul Pharmacol 57: 81-90.
    • (2012) Vascul Pharmacol , vol.57 , pp. 81-90
    • Aloysius, U.I.1    Achike, F.I.2    Mustafa, M.R.3
  • 8
    • 18044389382 scopus 로고    scopus 로고
    • Contribution of natural products to the discovery of the transient receptor potential (TRP) channels family and their functions
    • Calixto JB, Kassuya CA, Andre E, Ferreira J, (2005). Contribution of natural products to the discovery of the transient receptor potential (TRP) channels family and their functions. Pharmacol Ther 106: 179-208.
    • (2005) Pharmacol Ther , vol.106 , pp. 179-208
    • Calixto, J.B.1    Kassuya, C.A.2    Andre, E.3    Ferreira, J.4
  • 9
    • 0037354083 scopus 로고    scopus 로고
    • Endothelium-dependent and -independent vasodilator effects of eugenol in the rat mesenteric vascular bed
    • Criddle DN, Madeira SV, de Soares MR, (2003). Endothelium-dependent and -independent vasodilator effects of eugenol in the rat mesenteric vascular bed. J Pharm Pharmacol 55: 359-365.
    • (2003) J Pharm Pharmacol , vol.55 , pp. 359-365
    • Criddle, D.N.1    Madeira, S.V.2    De Soares, M.R.3
  • 10
    • 77954080107 scopus 로고    scopus 로고
    • Openers of small conductance calcium-activated potassium channels selectively enhance NO-mediated bradykinin vasodilatation in porcine retinal arterioles
    • Dalsgaard T, Kroigaard C, Misfeldt M, Bek T, Simonsen U, (2010). Openers of small conductance calcium-activated potassium channels selectively enhance NO-mediated bradykinin vasodilatation in porcine retinal arterioles. Br J Pharmacol 160: 1496-1508.
    • (2010) Br J Pharmacol , vol.160 , pp. 1496-1508
    • Dalsgaard, T.1    Kroigaard, C.2    Misfeldt, M.3    Bek, T.4    Simonsen, U.5
  • 13
    • 9744259465 scopus 로고    scopus 로고
    • Effects of eugenol, an essential oil, on the mechanical and electrical activities of cardiac muscle
    • Damiani CE, Moreira CM, Zhang HT, Creazzo TL, Vassallo DV, (2004). Effects of eugenol, an essential oil, on the mechanical and electrical activities of cardiac muscle. J Cardiovasc Pharmacol 44: 688-695.
    • (2004) J Cardiovasc Pharmacol , vol.44 , pp. 688-695
    • Damiani, C.E.1    Moreira, C.M.2    Zhang, H.T.3    Creazzo, T.L.4    Vassallo, D.V.5
  • 15
    • 77954926657 scopus 로고    scopus 로고
    • Transient receptor potential channels and vascular function
    • Earley S, Brayden JE, (2010). Transient receptor potential channels and vascular function. Clin Sci (Lond) 119: 19-36.
    • (2010) Clin Sci (Lond) , vol.119 , pp. 19-36
    • Earley, S.1    Brayden, J.E.2
  • 18
    • 77950267768 scopus 로고    scopus 로고
    • A dietary agonist of transient receptor potential cation channel V3 elicits endothelium-dependent vasodilation
    • Earley S, Gonzales AL, Garcia ZI, (2010). A dietary agonist of transient receptor potential cation channel V3 elicits endothelium-dependent vasodilation. Mol Pharmacol 77: 612-620.
    • (2010) Mol Pharmacol , vol.77 , pp. 612-620
    • Earley, S.1    Gonzales, A.L.2    Garcia, Z.I.3
  • 19
    • 84897850189 scopus 로고    scopus 로고
    • Endothelium and its alterations in cardiovascular diseases: Life style intervention
    • Favero G, Paganelli C, Buffoli B, Rodella LF, Rezzani R, (2014). Endothelium and its alterations in cardiovascular diseases: life style intervention. Biomed Res Int 2014, 801896.
    • (2014) Biomed Res Int , vol.2014 , pp. 801896
    • Favero, G.1    Paganelli, C.2    Buffoli, B.3    Rodella, L.F.4    Rezzani, R.5
  • 21
    • 84873408820 scopus 로고    scopus 로고
    • TRPV4 and the regulation of vascular tone
    • Filosa JA, Yao X, Rath G, (2013). TRPV4 and the regulation of vascular tone. J Cardiovasc Pharmacol 61: 113-119.
    • (2013) J Cardiovasc Pharmacol , vol.61 , pp. 113-119
    • Filosa, J.A.1    Yao, X.2    Rath, G.3
  • 22
    • 73849086120 scopus 로고    scopus 로고
    • + channels and sensory nerves
    • + channels and sensory nerves. J Hypertens 28: 102-110.
    • (2010) J Hypertens , vol.28 , pp. 102-110
    • Gao, F.1    Wang, D.H.2
  • 23
    • 0031561402 scopus 로고    scopus 로고
    • Differential expression of mammalian TRP homologues across tissues and cell lines
    • Garcia RL, Schilling WP, (1997). Differential expression of mammalian TRP homologues across tissues and cell lines. Biochem Biophys Res Commun 239: 279-283.
    • (1997) Biochem Biophys Res Commun , vol.239 , pp. 279-283
    • Garcia, R.L.1    Schilling, W.P.2
  • 24
    • 0036982855 scopus 로고    scopus 로고
    • Pharmacological studies on Myristica fragrans - Antidiarrheal, hypnotic, analgesic and hemodynamic (blood pressure) parameters
    • Grover JK, Khandkar S, Vats V, Dhunnoo Y, Das D, (2002). Pharmacological studies on Myristica fragrans-antidiarrheal, hypnotic, analgesic and hemodynamic (blood pressure) parameters. Methods Find Exp Clin Pharmacol 24: 675-680.
    • (2002) Methods Find Exp Clin Pharmacol , vol.24 , pp. 675-680
    • Grover, J.K.1    Khandkar, S.2    Vats, V.3    Dhunnoo, Y.4    Das, D.5
  • 27
    • 34548638854 scopus 로고    scopus 로고
    • Pharmacological evidence of calcium-channel blockade by essential oil of Ocimum gratissimum and its main constituent, eugenol, in isolated aortic rings from DOCA-salt hypertensive rats
    • Interaminense LF, Juca DM, Magalhaes PJ, Leal-Cardoso JH, Duarte GP, Lahlou S, (2007). Pharmacological evidence of calcium-channel blockade by essential oil of Ocimum gratissimum and its main constituent, eugenol, in isolated aortic rings from DOCA-salt hypertensive rats. Fundam Clin Pharmacol 21: 497-506.
    • (2007) Fundam Clin Pharmacol , vol.21 , pp. 497-506
    • Interaminense, L.F.1    Juca, D.M.2    Magalhaes, P.J.3    Leal-Cardoso, J.H.4    Duarte, G.P.5    Lahlou, S.6
  • 29
    • 84863001049 scopus 로고    scopus 로고
    • Eugenol - From the remote Maluku Islands to the international market place: A review of a remarkable and versatile molecule
    • Kamatou GP, Vermaak I, Viljoen AM, (2012). Eugenol-from the remote Maluku Islands to the international market place: a review of a remarkable and versatile molecule. Molecules 17: 6953-6981.
    • (2012) Molecules , vol.17 , pp. 6953-6981
    • Kamatou, G.P.1    Vermaak, I.2    Viljoen, A.M.3
  • 31
    • 33745952250 scopus 로고    scopus 로고
    • Evidence for a functional role of endothelial transient receptor potential V4 in shear stress-induced vasodilatation
    • Kohler R, Heyken WT, Heinau P, Schubert R, Si H, Kacik M, et al. (2006). Evidence for a functional role of endothelial transient receptor potential V4 in shear stress-induced vasodilatation. Arterioscler Thromb Vasc Biol 26: 1495-1502.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 1495-1502
    • Kohler, R.1    Heyken, W.T.2    Heinau, P.3    Schubert, R.4    Si, H.5    Kacik, M.6
  • 32
    • 1642459112 scopus 로고    scopus 로고
    • Cardiovascular effects of eugenol, a phenolic compound present in many plant essential oils, in normotensive rats
    • Lahlou S, Interaminense LF, Magalhaes PJ, Leal-Cardoso JH, Duarte GP, (2004). Cardiovascular effects of eugenol, a phenolic compound present in many plant essential oils, in normotensive rats. J Cardiovasc Pharmacol 43: 250-257.
    • (2004) J Cardiovasc Pharmacol , vol.43 , pp. 250-257
    • Lahlou, S.1    Interaminense, L.F.2    Magalhaes, P.J.3    Leal-Cardoso, J.H.4    Duarte, G.P.5
  • 34
    • 84880760080 scopus 로고    scopus 로고
    • Functional role of TRPV4-KCa2.3 signaling in vascular endothelial cells in normal and streptozotocin-induced diabetic rats
    • Ma X, Du J, Zhang P, Deng J, Liu J, Lam FF, et al. (2013). Functional role of TRPV4-KCa2.3 signaling in vascular endothelial cells in normal and streptozotocin-induced diabetic rats. Hypertension 62: 134-139.
    • (2013) Hypertension , vol.62 , pp. 134-139
    • Ma, X.1    Du, J.2    Zhang, P.3    Deng, J.4    Liu, J.5    Lam, F.F.6
  • 35
    • 1642303190 scopus 로고    scopus 로고
    • Effects of terpenoid phenol derivatives on calcium current in canine and human ventricular cardiomyocytes
    • Magyar J, Szentandrassy N, Banyasz T, Fulop L, Varro A, Nanasi PP, (2004). Effects of terpenoid phenol derivatives on calcium current in canine and human ventricular cardiomyocytes. Eur J Pharmacol 487: 29-36.
    • (2004) Eur J Pharmacol , vol.487 , pp. 29-36
    • Magyar, J.1    Szentandrassy, N.2    Banyasz, T.3    Fulop, L.4    Varro, A.5    Nanasi, P.P.6
  • 36
    • 77954331629 scopus 로고    scopus 로고
    • Guidelines for reporting experiments involving animals: The ARRIVE guidelines
    • McGrath J, Drummond G, McLachlan E, Kilkenny C, Wainwright C, (2010). Guidelines for reporting experiments involving animals: the ARRIVE guidelines. Br J Pharmacol 160: 1573-1576.
    • (2010) Br J Pharmacol , vol.160 , pp. 1573-1576
    • McGrath, J.1    Drummond, G.2    McLachlan, E.3    Kilkenny, C.4    Wainwright, C.5
  • 37
    • 77956182675 scopus 로고    scopus 로고
    • Evidence both L-type and non-L-type voltage-dependent calcium channels contribute to cerebral artery vasospasm following loss of NO in the rat
    • McNeish AJ, Altayo FJ, Garland CJ, (2010). Evidence both L-type and non-L-type voltage-dependent calcium channels contribute to cerebral artery vasospasm following loss of NO in the rat. Vascul Pharmacol 53: 151-159.
    • (2010) Vascul Pharmacol , vol.53 , pp. 151-159
    • McNeish, A.J.1    Altayo, F.J.2    Garland, C.J.3
  • 39
    • 77952891006 scopus 로고    scopus 로고
    • Cellular signaling and NO production
    • Michel T, Vanhoutte PM, (2010). Cellular signaling and NO production. Pflugers Arch 459: 807-816.
    • (2010) Pflugers Arch , vol.459 , pp. 807-816
    • Michel, T.1    Vanhoutte, P.M.2
  • 40
    • 0025080602 scopus 로고
    • Structure and function of small arteries
    • Mulvany MJ, Aalkjaer C, (1990). Structure and function of small arteries. Physiol Rev 70: 921-961.
    • (1990) Physiol Rev , vol.70 , pp. 921-961
    • Mulvany, M.J.1    Aalkjaer, C.2
  • 41
    • 0017702173 scopus 로고
    • Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats
    • Mulvany MJ, Halpern W, (1977). Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats. Circ Res 41: 19-26.
    • (1977) Circ Res , vol.41 , pp. 19-26
    • Mulvany, M.J.1    Halpern, W.2
  • 42
    • 0031280389 scopus 로고    scopus 로고
    • 2+-permeable currents in rat dorsal root ganglion cells
    • 2+-permeable currents in rat dorsal root ganglion cells. J Dent Res 76: 1737-1744.
    • (1997) J Dent Res , vol.76 , pp. 1737-1744
    • Ohkubo, T.1    Kitamura, K.2
  • 44
    • 84927745394 scopus 로고    scopus 로고
    • Eugenol dilates rat cerebral arteries by inhibiting smooth muscle cell voltage-dependent calcium channels
    • Peixoto-Neves D, Leal-Cardoso JH, Jaggar JH, (2014). Eugenol dilates rat cerebral arteries by inhibiting smooth muscle cell voltage-dependent calcium channels. J Cardiovasc Pharmacol 64: 401-406.
    • (2014) J Cardiovasc Pharmacol , vol.64 , pp. 401-406
    • Peixoto-Neves, D.1    Leal-Cardoso, J.H.2    Jaggar, J.H.3
  • 46
    • 80052363447 scopus 로고    scopus 로고
    • Acute simvastatin increases endothelial nitric oxide synthase phosphorylation via AMP-activated protein kinase and reduces contractility of isolated rat mesenteric resistance arteries
    • Rossoni LV, Wareing M, Wenceslau CF, Al-Abri M, Cobb C, Austin C, (2011). Acute simvastatin increases endothelial nitric oxide synthase phosphorylation via AMP-activated protein kinase and reduces contractility of isolated rat mesenteric resistance arteries. Clin Sci 121: 449-458.
    • (2011) Clin Sci , vol.121 , pp. 449-458
    • Rossoni, L.V.1    Wareing, M.2    Wenceslau, C.F.3    Al-Abri, M.4    Cobb, C.5    Austin, C.6
  • 48
    • 0033956534 scopus 로고    scopus 로고
    • Incidence of myoendothelial gap junctions in the proximal and distal mesenteric arteries of the rat is suggestive of a role in endothelium-derived hyperpolarizing factor-mediated responses
    • Sandow SL, Hill CE, (2000). Incidence of myoendothelial gap junctions in the proximal and distal mesenteric arteries of the rat is suggestive of a role in endothelium-derived hyperpolarizing factor-mediated responses. Circ Res 86: 341-346.
    • (2000) Circ Res , vol.86 , pp. 341-346
    • Sandow, S.L.1    Hill, C.E.2
  • 49
    • 24744452818 scopus 로고    scopus 로고
    • The double regulation of endothelial nitric oxide synthase by caveolae and caveolin: A paradox solved through the study of angiogenesis
    • Sbaa E, Frerart F, Feron O, (2005). The double regulation of endothelial nitric oxide synthase by caveolae and caveolin: a paradox solved through the study of angiogenesis. Trends Cardiovasc Med 15: 157-162.
    • (2005) Trends Cardiovasc Med , vol.15 , pp. 157-162
    • Sbaa, E.1    Frerart, F.2    Feron, O.3
  • 50
    • 34547135447 scopus 로고    scopus 로고
    • + channels directly control agonist-evoked nitric oxide synthesis in human vascular endothelial cells
    • + channels directly control agonist-evoked nitric oxide synthesis in human vascular endothelial cells. Am J Physiol Cell Physiol 293: C458-C467.
    • (2007) Am J Physiol Cell Physiol , vol.293 , pp. C458-C467
    • Sheng, J.Z.1    Braun, A.P.2
  • 52
    • 81555204267 scopus 로고    scopus 로고
    • Opening of small and intermediate calcium-activated potassium channels induces relaxation mainly mediated by nitric-oxide release in large arteries and endothelium-derived hyperpolarizing factor in small arteries from rat
    • Stankevicius E, Dalsgaard T, Kroigaard C, Beck L, Boedtkjer E, Misfeldt MW, et al. (2011). Opening of small and intermediate calcium-activated potassium channels induces relaxation mainly mediated by nitric-oxide release in large arteries and endothelium-derived hyperpolarizing factor in small arteries from rat. J Pharmacol Exp Ther 339: 842-850.
    • (2011) J Pharmacol Exp Ther , vol.339 , pp. 842-850
    • Stankevicius, E.1    Dalsgaard, T.2    Kroigaard, C.3    Beck, L.4    Boedtkjer, E.5    Misfeldt, M.W.6
  • 53
    • 84886481927 scopus 로고    scopus 로고
    • TRPV4 channel activation leads to endothelium-dependent relaxation mediated by nitric oxide and endothelium-derived hyperpolarizing factor in rat pulmonary artery
    • Sukumaran SV, Singh TU, Parida S, Narasimha Reddy CE, Thangamalai R, Kandasamy K, et al. (2013). TRPV4 channel activation leads to endothelium-dependent relaxation mediated by nitric oxide and endothelium-derived hyperpolarizing factor in rat pulmonary artery. Pharmacol Res 78: 18-27.
    • (2013) Pharmacol Res , vol.78 , pp. 18-27
    • Sukumaran, S.V.1    Singh, T.U.2    Parida, S.3    Narasimha Reddy, C.E.4    Thangamalai, R.5    Kandasamy, K.6
  • 54
    • 77954381277 scopus 로고    scopus 로고
    • Antihypertensive effects of Ocimum basilicum L. (OBL) on blood pressure in renovascular hypertensive rats
    • Umar A, Imam G, Yimin W, Kerim P, Tohti I, Berke B, et al. (2010). Antihypertensive effects of Ocimum basilicum L. (OBL) on blood pressure in renovascular hypertensive rats. Hypertens Res 33: 727-730.
    • (2010) Hypertens Res , vol.33 , pp. 727-730
    • Umar, A.1    Imam, G.2    Yimin, W.3    Kerim, P.4    Tohti, I.5    Berke, B.6
  • 57
    • 0037033077 scopus 로고    scopus 로고
    • Heat-evoked activation of TRPV4 channels in a HEK293 cell expression system and in native mouse aorta endothelial cells
    • Watanabe H, Vriens J, Suh SH, Benham CD, Droogmans G, Nilius B, (2002). Heat-evoked activation of TRPV4 channels in a HEK293 cell expression system and in native mouse aorta endothelial cells. J Biol Chem 277: 47044-47051.
    • (2002) J Biol Chem , vol.277 , pp. 47044-47051
    • Watanabe, H.1    Vriens, J.2    Suh, S.H.3    Benham, C.D.4    Droogmans, G.5    Nilius, B.6
  • 58
    • 84884254628 scopus 로고    scopus 로고
    • TRPV4 channel contributes to serotonin-induced pulmonary vasoconstriction and the enhanced vascular reactivity in chronic hypoxic pulmonary hypertension
    • Xia Y, Fu Z, Hu J, Huang C, Paudel O, Cai S, et al. (2013). TRPV4 channel contributes to serotonin-induced pulmonary vasoconstriction and the enhanced vascular reactivity in chronic hypoxic pulmonary hypertension. Am J Physiol Cell Physiol 305: C704-C715.
    • (2013) Am J Physiol Cell Physiol , vol.305 , pp. C704-C715
    • Xia, Y.1    Fu, Z.2    Hu, J.3    Huang, C.4    Paudel, O.5    Cai, S.6
  • 59
    • 33745742247 scopus 로고    scopus 로고
    • Oregano, thyme and clove-derived flavors and skin sensitizers activate specific TRP channels
    • Xu H, Delling M, Jun JC, Clapham DE, (2006). Oregano, thyme and clove-derived flavors and skin sensitizers activate specific TRP channels. Nat Neurosci 9: 628-635.
    • (2006) Nat Neurosci , vol.9 , pp. 628-635
    • Xu, H.1    Delling, M.2    Jun, J.C.3    Clapham, D.E.4
  • 60
    • 0033555844 scopus 로고    scopus 로고
    • Endothelium-dependent hyperpolarization and intercellular electrical coupling in Guinea-pig mesenteric arterioles
    • Yamamoto Y, Imaeda K, Suzuki H, (1999). Endothelium-dependent hyperpolarization and intercellular electrical coupling in Guinea-pig mesenteric arterioles. J Physiol 514 (Pt 2): 505-513.
    • (1999) J Physiol , vol.514 , pp. 505-513
    • Yamamoto, Y.1    Imaeda, K.2    Suzuki, H.3
  • 63
    • 79951549829 scopus 로고    scopus 로고
    • Transient receptor potential channel activation and endothelium-dependent dilation in the systemic circulation
    • Zhang DX, Gutterman DD, (2011). Transient receptor potential channel activation and endothelium-dependent dilation in the systemic circulation. J Cardiovasc Pharmacol 57: 133-139.
    • (2011) J Cardiovasc Pharmacol , vol.57 , pp. 133-139
    • Zhang, D.X.1    Gutterman, D.D.2
  • 64
    • 61749092039 scopus 로고    scopus 로고
    • Transient receptor potential vanilloid type 4-deficient mice exhibit impaired endothelium-dependent relaxation induced by acetylcholine in vitro and in vivo
    • Zhang DX, Mendoza SA, Bubolz AH, Mizuno A, Ge ZD, Li R, et al. (2009). Transient receptor potential vanilloid type 4-deficient mice exhibit impaired endothelium-dependent relaxation induced by acetylcholine in vitro and in vivo. Hypertension 53: 532-538.
    • (2009) Hypertension , vol.53 , pp. 532-538
    • Zhang, D.X.1    Mendoza, S.A.2    Bubolz, A.H.3    Mizuno, A.4    Ge, Z.D.5    Li, R.6
  • 65
    • 84884543456 scopus 로고    scopus 로고
    • Endothelial TRPV4 channels mediate dilation of cerebral arteries: Impairment and recovery in cerebrovascular pathologies related to Alzheimer's disease
    • Zhang L, Papadopoulos P, Hamel E, (2013). Endothelial TRPV4 channels mediate dilation of cerebral arteries: impairment and recovery in cerebrovascular pathologies related to Alzheimer's disease. Br J Pharmacol 170: 661-670.
    • (2013) Br J Pharmacol , vol.170 , pp. 661-670
    • Zhang, L.1    Papadopoulos, P.2    Hamel, E.3


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