A dietary agonist of transient receptor potential cation channel V3 elicits endothelium-dependent vasodilation

Molecular Pharmacology

Volumn 77, Issue 4, 2010, Pages 612-620

  Earley, Scott ^a   Gonzales, Albert L ^a   Garcia, Zarine I ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLYL ISOTHIOCYANATE; BARIUM CHLORIDE; CALCIUM ACTIVATED POTASSIUM CHANNEL; CALCIUM ION; CARVACROL; EUGENOL; NITRIC OXIDE SYNTHASE; POTASSIUM CHANNEL; PROSTAGLANDIN SYNTHASE; RUTHENIUM RED; TRANSIENT RECEPTOR POTENTIAL CHANNEL 1; VANILLOID RECEPTOR 3;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN ARTERY; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONTROLLED STUDY; ENDOTHELIUM; ENDOTHELIUM CELL; ENZYME ACTIVITY; HYPERPOLARIZATION; MALE; MEDITERRANEAN DIET; NONHUMAN; OREGANO; PRIORITY JOURNAL; RAT; RECEPTOR POTENTIAL; SMOOTH MUSCLE; VASODILATATION;

ANIMALS; CALCIUM; CALCIUM CHANNELS; CEREBRAL ARTERIES; DIET, MEDITERRANEAN; ENDOTHELIAL CELLS; ENDOTHELIUM-DEPENDENT RELAXING FACTORS; MALE; MONOTERPENES; ORIGANUM; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; RATS; RATS, SPRAGUE-DAWLEY; TRPV CATION CHANNELS; VASODILATION;

EID: 77950267768     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.109.060715     Document Type: Article

References (36)

1. Caterina MJ, Schumacher MA, Tominaga M, Rosen TA, Levine JD, and Julius D (1997) The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389:816-824.
2. Chung MK, Lee H, Mizuno A, Suzuki M, and Caterina MJ (2004) 2-aminoethoxydiphenyl borate activates and sensitizes the heat-gated ion channel TRPV3. J Neurosci 24:5177-5182.
3. + but may be due to spread of current from the endothelium in guinea pig arterioles. Am J Physiol Heart Circ Physiol 280:H2478-H2483.
4. + currents underlying the action of endothelium-derived hyperpolarizing factor in guinea-pig, rat and human blood vessels. J Physiol 531:359-373.
5. Dontas AS, Zerefos NS, Panagiotakos DB, Vlachou C, and Valis DA (2007) Mediterranean diet and prevention of coronary heart disease in the elderly. Clin Interv Aging 2:109-115.
6. + channels. Circ Res 104:987-994.
7. 2+ current impairs agonist-dependent vasorelaxation in TRP4-/- mice. Nat Cell Biol 3:121-127.
8. Fukuta H, Koshita M, Yamamoto Y, and Suzuki H (1999) Inhibition of the endothelium-dependent relaxation by 18beta-glycyrrhetinic acid in the guinea-pig aorta. Jpn J Physiol 49:267-274.
9. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260:3440-3450.
10. Hu HZ, Xiao R, Wang C, Gao N, Colton CK, Wood JD, and Zhu MX (2006) Potentiation of TRPV3 channel function by unsaturated fatty acids. J Cell Physiol 208:201-212.
11. Inoue R, Jensen LJ, Shi J, Morita H, Nishida M, Honda A, and Ito Y (2006) Transient receptor potential channels in cardiovascular function and disease. Circ Res 99:119-131.
12. Jordt SE, Bautista DM, Chuang HH, McKemy DD, Zygmunt PM, Högestätt ED, Meng ID, and Julius D (2004) Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1. Nature 427:260-265.
13. 2+] in cerebral arteries of rat by membrane potential and intravascular pressure. J Physiol 508:199-209.
14. Knot HJ, Zimmermann PA, and Nelson MT (1996) Extracellular K(+)-induced hyperpolarizations and dilatations of rat coronary and cerebral arteries involve inward rectifier K(+) channels. J Physiol 492:419-430.
15. Köhler R, Heyken WT, Heinau P, Schubert R, Si H, Kacik M, Busch C, Grgic I, Maier T, and Hoyer J (2006) Evidence for a functional role of endothelial transient receptor potential V4 in shear stress-induced vasodilatation. Arterioscler Thromb Vasc Biol 26:1495-1502.
16. Lairon D (2007) Intervention studies on Mediterranean diet and cardiovascular risk. Mol Nutr Food Res 51:1209-1214.
17. Ledoux J, Taylor MS, Bonev AD, Hannah RM, Solodushko V, Shui B, Tallini Y, Kotlikoff MI, and Nelson MT (2008) Functional architecture of inositol 1,4,5-trisphosphate signaling in restricted spaces of myoendothelial projections. Proc Natl Acad Sci USA 105:9627-9632.
18. Marrelli SP, O'neil RG, Brown RC, and Bryan RM Jr (2007) PLA2 and TRPV4 channels regulate endothelial calcium in cerebral arteries. Am J Physiol Heart Circ Physiol 292:H1390-H1397.
19. McKemy DD, Neuhausser WM, and Julius D (2002) Identification of a cold receptor reveals a general role for TRP channels in thermosensation. Nature 416:52-58.
20. McNamara CR, Mandel-Brehm J, Bautista DM, Siemens J, Deranian KL, Zhao M, Hayward NJ, Chong JA, Julius D, Moran MM, et al. (2007) TRPA1 mediates formalin-induced pain. Proc Natl Acad Sci USA 104:13525-13530.
21. Moqrich A, Hwang SW, Earley TJ, Petrus MJ, Murray AN, Spencer KS, Andahazy M, Story GM, and Patapoutian A (2005) Impaired thermosensation in mice lacking TRPV3, a heat and camphor sensor in the skin. Science 307:1468-1472.
22. Peier AM, Moqrich A, Hergarden AC, Reeve AJ, Andersson DA, Story GM, Earley TJ, Dragoni I, McIntyre P, Bevan S, et al. (2002a) A TRP channel that senses cold stimuli and menthol. Cell 108:705-715.
23. Peier AM, Reeve AJ, Andersson DA, Moqrich A, Earley TJ, Hergarden AC, Story GM, Colley S, Hogenesch JB, McIntyre P, et al. (2002b) A heat-sensitive TRP channel expressed in keratinocytes. Science 296:2046-2049.
24. Sandow SL and Hill CE (2000) Incidence of myoendothelial gap junctions in the proximal and distal mesenteric arteries of the rat is suggestive of a role in endothelium-derived hyperpolarizing factor-mediated responses. Circ Res 86:341-346.
25. Sarer E, Scheffer JJ, and Baerheim Svendsen A (1982) Monoterpenes in the essential oil of Origanum majorana. Planta Medica 46:236-239.
26. Singh RB, Niaz MA, Sharma JP, Kumar R, Rastogi V, and Moshiri M (1997) Randomized, double-blind, placebo-controlled trial of fish oil and mustard oil in patients with suspected acute myocardial infarction: the Indian experiment of infarct survival-4. Cardiovasc Drugs Ther 11:485-491.
27. Smith PD, Brett SE, Luykenaar KD, Sandow SL, Marrelli SP, Vigmond EJ, and Welsh DG (2008) KIR channels function as electrical amplifiers in rat vascular smooth muscle. J Physiol 586:1147-1160.
28. Smith GD, Gunthorpe MJ, Kelsell RE, Hayes PD, Reilly P, Facer P, Wright JE, Jerman JC, Walhin JP, Ooi L, et al. (2002) TRPV3 is a temperature-sensitive vanilloid receptor-like protein. Nature 418:186-190.
29. Story GM, Peier AM, Reeve AJ, Eid SR, Mosbacher J, Hricik TR, Earley TJ, Hergarden AC, Andersson DA, Hwang SW, et al. (2003) ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures. Cell 112:819-829.
30. + (SK3) channels modulates arterial tone and blood pressure. Circ Res 93:124-131.
31. Ueda T, Yamada T, Ugawa S, Ishida Y, and Shimada S (2009) TRPV3, a thermosensitive channel is expressed in mouse distal colon epithelium. Biochem Biophys Res Commun 383:130-134.
32. Vogt-Eisele AK, Weber K, Sherkheli MA, Vielhaber G, Panten J, Gisselmann G, and Hatt H (2007) Monoterpenoid agonists of TRPV3. Br J Pharmacol 151:530-540.
33. Vriens J, Owsianik G, Fisslthaler B, Suzuki M, Janssens A, Voets T, Morisseau C, Hammock BD, Fleming I, Busse R, et al. (2005) Modulation of the Ca2 permeable cation channel TRPV4 by cytochrome P450 epoxygenases in vascular endothelium. Circ Res 97:908-915.
34. Xu H, Delling M, Jun JC, and Clapham DE (2006) Oregano, thyme and clove-derived flavors and skin sensitizers activate specific TRP channels. Nat Neurosci 9:628-635.
35. Xu H, Ramsey IS, Kotecha SA, Moran MM, Chong JA, Lawson D, Ge P, Lilly J, Silos-Santiago I, Xie Y, et al. (2002) TRPV3 is a calcium-permeable temperature-sensitive cation channel. Nature 418:181-186.
36. Yang XR, Lin MJ, McIntosh LS, and Sham JS (2006) Functional expression of transient receptor potential melastatin- and vanilloid-related channels in pulmonary arterial and aortic smooth muscle. Am J Physiol Lung Cell Mol Physiol 290:L1267-L1276.