Opening of small and intermediate calcium-activated potassium channels induces relaxation mainly mediated by nitric-oxide release in large arteries and endothelium- derived hyperpolarizing factor in small arteries from rat

Journal of Pharmacology and Experimental Therapeutics

Volumn 339, Issue 3, 2011, Pages 842-850

  Stankevičius, Edgaras ^a,b   Dalsgaard, Thomas ^a   Kroigaard, Christel ^a   Beck, Lilliana ^a   Boedtkjer, Ebbe ^a   Misfeldt, Mikkel W ^c   Nielsen, Gorm ^d   Schjorring, Olav ^a   Hughes, Alun ^e   Simonsen, Ulf ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b KAUNAS UNIVERSITY OF MEDICINE   (Lithuania)

^c AARHUS UNIVERSITY HOSPITAL   (Denmark)

^d UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^e NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

6,7 DICHLORO 1H INDOLE 2,3 DIONE 3 OXIME; APAMIN; CHARYBDOTOXIN; ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR; IBERIOTOXIN; INTERMEDIATE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; N(G),N(G) DIMETHYLARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NS 309; POTASSIUM CHANNEL AFFECTING AGENT; SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTERY DILATATION; ARTERY ENDOTHELIUM; ARTICLE; CALCIUM CURRENT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; GENE EXPRESSION; HUMAN; HUMAN CELL; MALE; MESENTERIC ARTERY; MYOGRAPHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; UMBILICAL VEIN ENDOTHELIAL CELL;

ANILINE COMPOUNDS; ANIMALS; ANTHRACENES; APAMIN; BIOLOGICAL FACTORS; DRUG EVALUATION, PRECLINICAL; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; INDOLES; MALE; MESENTERIC ARTERIES; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXIMES; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; PROPANE; PYRAZOLES; RATS; RATS, WISTAR; VASODILATION; VASODILATOR AGENTS;

EID: 81555204267     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.111.179242     Document Type: Article

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