Ginsenoside Re protects methamphetamine-induced mitochondrial burdens and proapoptosis via genetic inhibition of protein kinase C δ in human neuroblastoma dopaminergic SH-SY5Y cell lines

Journal of Applied Toxicology

Volumn 35, Issue 8, 2015, Pages 927-944

  Nam, Yunsung ^a   Wie, Myung Bok ^a   Shin, Eun Joo ^a   Nguyen, Thuy Ty Lan ^a   Nah, Seung Yeol ^b   Ko, Sung Kwon ^c   Jeong, Ji Hoon ^d   Jang, Choon Gon ^e   Kim, Hyoung Chun ^a  

^a Kangwon National University   (South Korea)

^b Konkuk University   (South Korea)

^c Semyung University   (South Korea)

^d Chung Ang University   (South Korea)

^e Sungkyunkwan University   (South Korea)

Author keywords

Apoptosis; Ginsenoside Re; Glutathione; Glutathione peroxidase; Methamphetamine; Mitochondria; Oxidative damage; Tyrosine hydroxylase

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CASPASE 3; CYTOCHROME; CYTOCHROME C; DNA NUCLEOTIDYLEXOTRANSFERASE; GINSENOSIDE RE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; METHAMPHETAMINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN KINASE C DELTA; SUPEROXIDE DISMUTASE; TYROSINE 3 MONOOXYGENASE; ANTIOXIDANT; APOPTOSIS REGULATORY PROTEIN; CENTRAL STIMULANT AGENT; GINSENOSIDE; NEUROPROTECTIVE AGENT;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; LIPID PEROXIDATION; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NEUROBLASTOMA; NEUROBLASTOMA CELL; NEUROPROTECTION; OXIDATION; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN SECRETION; TUNEL ASSAY; ANTAGONISTS AND INHIBITORS; CYTOSOL; DOPAMINERGIC NERVE CELL; DRUG EFFECTS; GENETICS; METABOLISM; TUMOR CELL LINE;

MUS;

ANTIOXIDANTS; APOPTOSIS REGULATORY PROTEINS; CELL LINE, TUMOR; CENTRAL NERVOUS SYSTEM STIMULANTS; CYTOCHROMES C; CYTOSOL; DOPAMINERGIC NEURONS; GINSENOSIDES; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; METHAMPHETAMINE; MITOCHONDRIA; NEUROPROTECTIVE AGENTS; PROTEIN KINASE C-DELTA; TYROSINE 3-MONOOXYGENASE;

EID: 84932194234     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.3093     Document Type: Article

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