Ginsenoside Re rescues methamphetamine-induced oxidative damage, mitochondrial dysfunction, microglial activation, and dopaminergic degeneration by inhibiting the protein kinase Cδ gene

Molecular Neurobiology

Volumn 49, Issue 3, 2014, Pages 1400-1421

  Shin, Eun Joo ^a   Shin, Seung Woo ^a   Nguyen, Thuy Ty Lan ^a   Park, Dae Hun ^a,b   Wie, Myung Bok ^a   Jang, Choon Gon ^c   Nah, Seung Yeol ^d   Yang, Byung Wook ^e   Ko, Sung Kwon ^f   Nabeshima, Toshitaka ^g   Kim, Hyoung Chun ^a  

^a Kangwon National University   (South Korea)

^b Dongshin University   (South Korea)

^c Sungkyunkwan University   (South Korea)

^d Konkuk University   (South Korea)

^e Chung Ang University   (South Korea)

^f Semyung University   (South Korea)

^g MEIJO UNIVERSITY   (Japan)

Author keywords

Apoptosis; Dopamine; Ginsenoside Re; Methamphetamine; Mitochondria; Oxidative damage; Protein kinase C

Indexed keywords

GINSENOSIDE RE; METHAMPHETAMINE; PROTEIN KINASE C DELTA; GINSENOSIDE; PROTEIN KINASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOPAMINERGIC NERVE CELL; DRUG MECHANISM; MALE; MICROGLIA; MOUSE; NERVE CELL DEGENERATION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CHEMICALLY INDUCED; CHEMISTRY; DRUG EFFECTS; METABOLISM; MITOCHONDRION; NERVE DEGENERATION; PHYSIOLOGY; TOXICITY; TRANSGENIC MOUSE;

ANIMALS; DOPAMINERGIC NEURONS; GINSENOSIDES; METHAMPHETAMINE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROGLIA; MITOCHONDRIA; NERVE DEGENERATION; OXIDATIVE STRESS; PROTEIN KINASE C-DELTA; PROTEIN KINASE INHIBITORS;

EID: 84902544775     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-013-8617-1     Document Type: Article

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