Protective potential of IL-6 against trimethyltin-induced neurotoxicity in vivo

Free Radical Biology and Medicine

Volumn 52, Issue 7, 2012, Pages 1159-1174

  Tran, Hoang Yen Phi ^a,g   Shin, Eun Joo ^a   Saito, Kuniaki ^b   Nguyen, Xuan Khanh Thi ^a   Chung, Yoon Hee ^c   Jeong, Ji Hoon ^c   Bach, Jae Hyung ^a   Park, Dae Hun ^a   Yamada, Kiyofumi ^d   Nabeshima, Toshitaka ^e   Yoneda, Yukio ^f   Kim, Hyoung Chun ^a  

^a Kangwon National University   (South Korea)

^b KYOTO UNIVERSITY   (Japan)

^c Chung Ang University   (South Korea)

^d NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e MEIJO UNIVERSITY   (Japan)

^f KANAZAWA UNIVERSITY   (Japan)

^g UNIVERSITY OF MEDICINE AND PHARMACY AT HO CHI MINH CITY   (Viet Nam)

Author keywords

Free radicals; Glutathione; Hippocampus; IL 6 knockout mice; Nuclear factor E2 related factor 2; Oxidative stress; Phosphoinositol 3 kinase Akt; Recombinant IL 6 protein; Trimethyltin

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ACETYLCYSTEINE; CASPASE 3; GAMMA INTERFERON; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; HEME OXYGENASE 1; INTERLEUKIN 6; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN 14 3 3; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; RECOMBINANT INTERLEUKIN 6; TRIMETHYLTIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CONTROLLED STUDY; CONVULSION; HIPPOCAMPUS; HOMEOSTASIS; IN VIVO STUDY; LIPID PEROXIDATION; MOUSE; NERVE CELL DEGENERATION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATION; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SEIZURE; UPREGULATION;

ANIMALS; BLOTTING, WESTERN; CASPASE 3; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GLUTATHIONE; INTERFERON-GAMMA; INTERLEUKIN-6; MALE; MALONDIALDEHYDE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURONS; NEUROTOXICITY SYNDROMES; NF-E2-RELATED FACTOR 2; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRIMETHYLTIN COMPOUNDS; TUMOR NECROSIS FACTOR-ALPHA;

MUS;

EID: 84862778033     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.12.008     Document Type: Article

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