Protection against kainate neurotoxicity by ginsenosides: Attenuation of convulsive behavior, mitochondrial dysfunction, and oxidative stress

Journal of Neuroscience Research

Volumn 87, Issue 3, 2009, Pages 710-722

  Shin, Eun Joo ^a   Jeong, Ji Hoon ^b   Kim, A Young ^c   Koh, Young Ho ^c   Nah, Seung Yeoul ^d   Kim, Won Ki ^e   Ko, Kwang Ho ^f   Kim, Hyun Ji ^a   Wie, Myung Bok ^a   Kwon, Yong Soo ^a   Yoneda, Yukio ^g   Kim, Hyoung Chun ^a  

^a Kangwon National University   (South Korea)

^b Chung Ang University   (South Korea)

^c Hallym University   (South Korea)

^d Konkuk University   (South Korea)

^e Korea University College of Medicine   (South Korea)

^f Seoul National University   (South Korea)

^g KANAZAWA UNIVERSITY   (Japan)

Author keywords

GSH GSSG; Hippocampus; Mitochondrial membrane potential; Mn superoxide dismutase; Ultrastructural degeneration

Indexed keywords

CALCIUM ION; CHIKUSETSU SAPONIN; GINSENOSIDE; GINSENOSIDE RA 1; GINSENOSIDE RB 1; GINSENOSIDE RB 2; GINSENOSIDE RC; GINSENOSIDE RD; GINSENOSIDE RE; GINSENOSIDE RF; GINSENOSIDE RG 1; GINSENOSIDE RG 2; GINSENOSIDE RG 3; GLUTATHIONE; GLUTATHIONE DISULFIDE; MANGANESE SUPEROXIDE DISMUTASE; SAPONIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONVULSION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOSE RESPONSE; LIPID PEROXIDATION; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ANIMALS; ANTICONVULSANTS; ANTIOXIDANTS; CALCIUM; GINSENOSIDES; GLUTATHIONE; HIPPOCAMPUS; KAINIC ACID; LIPID PEROXIDATION; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MOTOR ACTIVITY; NERVE DEGENERATION; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; SEIZURES; SUPEROXIDE DISMUTASE;

EID: 62849096825     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21880     Document Type: Article

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