Involvement of protein kinase C delta in the alteration of mitochondrial mass in human cells under oxidative stress

Free Radical Biology and Medicine

Volumn 40, Issue 12, 2006, Pages 2136-2146

  Lee, Cheng Feng ^a   Chen, Yin Chiu ^a   Liu, Chun Yi ^a   Wei, Yau Huei ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

H2O2; MERRF; Mitochondrial mass; MnSOD; p53; PKC

Indexed keywords

BISTRATENE A; HYDROGEN PEROXIDE; MANGANESE SUPEROXIDE DISMUTASE; PROTEIN KINASE C DELTA; PROTEIN KINASE INHIBITOR; PROTEIN P53; ROTTLERIN;

ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; CORRELATION ANALYSIS; DISORDERS OF MITOCHONDRIAL FUNCTIONS; EXPOSURE; HUMAN; HUMAN CELL; INNER CELL MASS; INTRACELLULAR SPACE; MERRF SYNDROME; MITOCHONDRION; OSTEOSARCOMA CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; SKIN FIBROBLAST; UPREGULATION;

ACETAMIDES; ACETOPHENONES; BENZOPYRANS; CELL LINE, TUMOR; ENZYME ACTIVATION; ENZYME INHIBITORS; FIBROBLASTS; HUMANS; HYDROGEN PEROXIDE; MERRF SYNDROME; MITOCHONDRIA; OXIDATIVE STRESS; PROTEIN KINASE C-DELTA; PYRANS; SKIN; SPIRO COMPOUNDS; SUPEROXIDE DISMUTASE; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 33745137507     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2006.02.008     Document Type: Article

References (63)

1. + leak and ROS generation: an odd couple. Free Radic. Biol. Med. 38 (2005) 12-23
2. Brookes P.S., Yoon Y., Robotham J.L., Anders M.W., and Sheu S.S. Calcium, ATP, and ROS: a mitochondrial love-hate triangle. Am. J. Physiol. Cell Physiol. 287 (2004) C817-C833
3. Emerit J., Edeas M., and Bricaire F. Neurodegenerative diseases and oxidative stress. Biomed. Pharmacother. 58 (2004) 39-46
4. Zeviani M., and Spinazzola A. Mitochondrial disorders. Curr. Neurol. Neurosci. Rep. 3 (2003) 423-432
5. DiMauro S. Mitochondrial diseases. Biochim. Biophys. Acta 1658 (2004) 80-88
6. Wei Y.H., and Lee H.C. Mitochondrial DNA mutations and oxidative stress in mitochondrial diseases. Adv. Clin. Chem. 37 (2003) 83-128
7. Shy G.M., and Gonatas N.K. Human myopathy with giant abnormal mitochondria. Science 145 (1964) 493-496
8. Musashi M., Ota S., and Shiroshita N. The role of protein kinase C isoforms in cell proliferation and apoptosis. Int. J. Hematol. 72 (2000) 12-19
9. Nishizuka Y. Protein kinase C and lipid signaling for sustained cellular responses. FASEB J. 9 (1995) 484-496
10. Mellor H., and Parker P.J. The extended protein kinase C superfamily. Biochem. J. 332 (1998) 281-292
11. 2-induced tyrosine phosphorylation of protein kinase Cδ by a mechanism independent of inhibition of protein-tyrosine phosphatase in CHO and COS-7 cells. Biochem. Biophys. Res. Commun. 273 (2000) 960-966
12. 2. Proc. Natl. Acad. Sci. USA 94 (1997) 11233-11237
13. Steinberg S.F. Distinctive activation mechanisms and functions for protein kinase Cδ. Biochem. J. 384 (2004) 449-459
14. Talior I., Tennenbaum T., Kuroki T., and Eldar-Finkelman H. PKC-δ-dependent activation of oxidative stress in adipocytes of obese and insulin-resistant mice: role for NADPH oxidase. Am. J. Physiol. Endocrinol. Metab. 288 (2005) E405-E411
15. Harrington E.O., Loffler J., Nelson P.R., Kent K.C., Simons M., and Ware J.A. Enhancement of migration by protein kinase Cα and inhibition of proliferation and cell cycle progression by protein kinase Cδ in capillary endothelial cells. J. Biol. Chem. 272 (1997) 7390-7397
16. Mishima K., Ohno S., Shitara N., Yamaoka K., and Suzuki K. Opposite effects of the overexpression of protein kinase C γ and δ on the growth properties of human glioma cell line U251 MG. Biochem. Biophys. Res. Commun. 201 (1994) 363-372
17. Watanabe T., Ono Y., Taniyama Y., Hazama K., Igarashi K., Ogita K., Kikkawa U., and Nishizuka Y. Cell division arrest induced by phorbol ester in CHO cells overexpressing protein kinase C-δ subspecies. Proc. Natl. Acad. Sci. USA 89 (1992) 10159-10163
18. Banan A., Fields J.Z., Farhadi A., Talmage D.A., Zhang L., and Keshavarzian A. Activation of δ-isoform of protein kinase C is required for oxidant-induced disruption of both the microtubule cytoskeleton and permeability barrier of intestinal epithelia. J. Pharmacol. Exp. Ther. 303 (2002) 17-28
19. Lee C.F., Liu C.Y., Hsieh R.H., and Wei Y.H. Oxidative stress-induced depolymerization of microtubules and alteration of mitochondrial mass in human cells. Ann. N.Y. Acad. Sci. 1042 (2005) 246-254
20. Lee H.C., Yin P.H., Lu C.Y., Chi C.W., and Wei Y.H. Increase of mitochondria and mitochondrial DNA in response to oxidative stress in human cells. Biochem. J. 348 (2000) 425-432
21. 10 in human cells harboring large-scale deletion of mitochondrial DNA. Ann. N.Y. Acad. Sci. 1042 (2005) 429-438
22. Duronio V., Scheid M.P., and Ettinger S. Downstream signalling events regulated by phosphatidylinositol 3-kinase activity. Cell. Signal. 10 (1998) 233-239
23. Ettinger S.L., Lauener R.W., and Duronio V. Protein kinase C delta specifically associates with phosphatidylinositol 3-kinase following cytokine stimulation. J. Biol. Chem. 271 (1996) 14514-14518
24. Rybin V.O., Sabri A., Short J., Braz J.C., Molkentin J.D., and Steinberg S.F. Cross-regulation of novel protein kinase C (PKC) isoform function in cardiomyocytes. Role of PKCε in activation loop phosphorylations and PKCδ in hydrophobic motif phosphorylations. J. Biol. Chem. 278 (2003) 14555-14564
25. Parekh D., Ziegler W., Yonezawa K., Hara K., and Parker P.J. Mammalian TOR controls one of two kinase pathways acting upon nPKCδ and nPKCε. J. Biol. Chem. 274 (1999) 34758-34764
26. Kitamura K., Mizuno K., Etoh A., Akita Y., Miyamoto A., Nakayama K., and Ohno S. The second phase activation of protein kinase Cδ at late G1 is required for DNA synthesis in serum-induced cell cycle progression. Genes Cells 8 (2003) 311-324
27. Griffiths G., Garrone B., Deacon E., Owen P., Pongracz J., Mead G., Bradwell A., Watters D., and Lord J. The polyether bistratene A activates protein kinase C-δ and induces growth arrest in HL60 cells. Biochem. Biophys. Res. Commun. 222 (1996) 802-808
28. Gschwendt M., Muller H.J., Kielbassa K., Zang R., Kittstein W., Rincke G., and Marks F. Rottlerin, a novel protein kinase inhibitor. Biochem. Biophys. Res. Commun. 199 (1994) 93-98
29. Lu C.Y., Wang E.K., Lee H.C., Tsay H.J., and Wei Y.H. Increased expression of manganese-superoxide dismutase in fibroblasts of patients with CPEO syndrome. Mol. Genet. Metab. 80 (2003) 321-329
30. McKenzie M., Liolitsa D., and Hanna M.G. Mitochondrial disease: mutations and mechanisms. Neurochem. Res. 29 (2004) 589-600
31. Wei Y.H., Lu C.Y., Wei C.Y., Ma Y.S., and Lee H.C. Oxidative stress in human aging and mitochondrial disease-consequences of defective mitochondrial respiration and impaired antioxidant enzyme system. Chin. J. Physiol. 44 (2001) 1-11
32. Lee H.C., Yin P.H., Chi C.W., and Wei Y.H. Increase in mitochondrial mass in human fibroblasts under oxidative stress and during replicative cell senescence. J. Biomed. Sci. 9 (2002) 517-526
33. Wei Y.H., Lee C.F., Lee H.C., Ma Y.S., Wang C.W., Lu C.Y., and Pang C.Y. Increases of mitochondrial mass and mitochondrial genome in association with enhanced oxidative stress in human cells harboring 4,977 bp-deleted mitochondrial DNA. Ann. N.Y. Acad. Sci. 928 (2001) 97-112
34. Brodie C., and Blumberg P.M. Regulation of cell apoptosis by protein kinase Cδ. Apoptosis 8 (2003) 19-27
35. Majumder P.K., Pandey P., Sun X., Cheng K., Datta R., Saxena S., Kharbanda S., and Kufe D. Mitochondrial translocation of protein kinase Cδ in phorbol ester-induced cytochrome c release and apoptosis. J. Biol. Chem. 275 (2000) 21793-21796
36. Murriel C.L., Churchill E., Inagaki K., Szweda L.I., and Mochly-Rosen D. Protein kinase Cδ activation induces apoptosis in response to cardiac ischemia and reperfusion damage: a mechanism involving BAD and the mitochondria. J. Biol. Chem. 279 (2004) 47985-47991
37. Basu A. Involvement of protein kinase C-δ in DNA damage-induced apoptosis. J. Cell Mol. Med. 7 (2003) 341-350
38. Gutcher I., Webb P.R., and Anderson N.G. The isoform-specific regulation of apoptosis by protein kinase C. Cell. Mol. Life Sci. 60 (2003) 1061-1070
39. Conte M., Soper B., Chang Q., and Tepperman B. The role of PKCδ and PKCε in the neonatal rat colon in response to hypoxia challenge. Pediatr. Res. 55 (2004) 27-33
40. Chang Q., and Tepperman B.L. Effect of selective PKC isoform activation and inhibition on TNF-α-induced injury and apoptosis in human intestinal epithelial cells. Br. J. Pharmacol. 140 (2003) 41-52
41. Braun M.U., and Mochly-Rosen D. Opposing effects of δ-and ζ-protein kinase C isozymes on cardiac fibroblast proliferation: use of isozyme-selective inhibitors. J. Mol. Cell. Cardiol. 35 (2003) 895-903
42. Farhadi A., Keshavarzian A., Ranjbaran Z., Fields J.Z., and Banan A. The role of protein kinase C isoforms in modulating injury and repair of the intestinal barrier. J. Pharmacol. Exp. Ther. 316 (2006) 1-7
43. Frey M.R., Leontieva O., Watters D.J., and Black J.D. Stimulation of protein kinase C-dependent and-independent signaling pathways by bistratene A in intestinal epithelial cells. Biochem. Pharmacol. 61 (2001) 1093-1100
44. Rojas E., Valverde M., Vega L., Salvador A., Ramirez P., Herrera L.A., Watters D., Lavin M.F., and Ostrosky-Wegman P. Genotoxic effects of bistratene A on human lymphocytes. Mutat. Res. 367 (1996) 169-175
45. Gemin A., Sweet S., Preston T.J., and Singh G. Regulation of the cell cycle in response to inhibition of mitochondrial generated energy. Biochem. Biophys. Res. Commun. 332 (2005) 1122-1132
46. Sweet S., and Singh G. Changes in mitochondrial mass, membrane potential, and cellular adenosine triphosphate content during the cell cycle of human leukemic (HL-60) cells. J. Cell. Physiol. 180 (1999) 91-96
47. Karbowski M., Spodnik J.H., Teranishi M., Wozniak M., Nishizawa Y., Usukura J., and Wakabayashi T. Opposite effects of microtubule-stabilizing and microtubule-destabilizing drugs on biogenesis of mitochondria in mammalian cells. J. Cell Sci. 114 (2001) 281-291
48. Filosto M., Tonin P., Vattemi G., Spagnolo M., Rizzuto N., and Tomelleri G. Antioxidant agents have a different expression pattern in muscle fibers of patients with mitochondrial diseases. Acta Neuropathol. 103 (2002) 215-220
49. Kirkinezos I.G., and Moraes C.T. Reactive oxygen species and mitochondrial diseases. Semin. Cell Dev. Biol. 12 (2001) 449-457
50. Ma Y.S., Chen Y.C., Lu C.Y., Liu C.Y., and Wei Y.H. Upregulation of matrix metalloproteinase 1 and disruption of mitochondrial network in skin fibroblasts of patients with MERRF syndrome. Ann. N.Y. Acad. Sci. 1042 (2005) 55-63
51. Ria F., Landriscina M., Remiddi F., Rosselli R., Iacoangeli M., Scerrati M., Pani G., Borrello S., and Galeotti T. The level of manganese superoxide dismutase content is an independent prognostic factor for glioblastoma. Biological mechanisms and clinical implications. Br. J. Cancer 84 (2001) 529-534
52. Hussain S.P., Amstad P., He P., Robles A., Lupold S., Kaneko I., Ichimiya M., Sengupta S., Mechanic L., Okamura S., Hofseth L.J., Moake M., Nagashima M., Forrester K.S., and Harris C.C. p53-induced up-regulation of MnSOD and GPx but not catalase increases oxidative stress and apoptosis. Cancer Res. 64 (2004) 2350-2356
53. Abbas T., White D., Hui L., Yoshida K., Foster D.A., and Bargonetti J. Inhibition of human p53 basal transcription by down-regulation of protein kinase C δ. J. Biol. Chem. 279 (2004) 9970-9977
54. 2-treated bovine endothelial cells. Free Radic. Res. 36 (2002) 1147-1153
55. Chang N.S. A potential role of p53 and WOX1 in mitochondrial apoptosis. Int. J. Mol. Med. 9 (2002) 19-24
56. Donahue R.J., Razmara M., Hoek J.B., and Knudsen T.B. Direct influence of the p53 tumor suppressor on mitochondrial biogenesis and function. FASEB J. 15 (2001) 635-644
57. DiMauro S., Tanji K., Bonilla E., Pallotti F., and Schon E.A. Mitochondrial abnormalities in muscle and other aging cells: classification, causes, and effects. Muscle Nerve 26 (2002) 597-607
58. Wallace D.C. Animal models for mitochondrial disease. Methods Mol. Biol. 197 (2002) 3-54
59. 2 production and response to stress conditions by mitochondrial fractions from rat liver. J. Bioenerg. Biomembr. 34 (2002) 115-125
60. Salo D.C., Donovan C.M., and Davies K.J. HSP70 and other possible heat shock or oxidative stress proteins are induced in skeletal muscle, heart, and liver during exercise. Free Radic. Biol. Med. 11 (1991) 239-246
61. Mitsumoto A., Takeuchi A., Okawa K., and Nakagawa Y. A subset of newly synthesized polypeptides in mitochondria from human endothelial cells exposed to hydroperoxide stress. Free Radic. Biol. Med. 32 (2002) 22-37
62. Scarpulla R.C. Nuclear control of respiratory chain expression in mammalian cells. J. Bioenerg. Biomembr. 29 (1997) 109-119
63. Suzuki H., Kumagai T., Goto A., and Sugiura T. Increase in intracellular hydrogen peroxide and upregulation of a nuclear respiratory gene evoked by impairment of mitochondrial electron transfer in human cells. Biochem. Biophys. Res. Commun. 249 (1998) 542-545