Rescue of PINK1 protein null-specific mitochondrial complex IV deficits by ginsenoside Re activation of nitric oxide signaling

Journal of Biological Chemistry

Volumn 287, Issue 53, 2012, Pages 44109-44120

  Kim, Kyung Hee ^a   Song, Karen ^a   Yoon, Seung Hee ^a   Shehzad, Omer ^b   Kim, Yeong Shik ^b   Son, Jin H ^a  

^a Ewha Womans University   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ALLYLAMINO; CO-EXPRESSION; DRUG SCREENING; GELDANAMYCIN; GINSENOSIDE RE; METHYL ESTERS; MITOCHONDRIAL COMPLEX; MITOCHONDRIAL DYSFUNCTION; MITOCHONDRIAL FUNCTION; NEURONAL CELL; NITRIC OXIDE SIGNALING; OVER-EXPRESSION; PARKINSON'S DISEASE; PHARMACOLOGICAL EFFECTS;

AMINO ACIDS; NEURODEGENERATIVE DISEASES;

NITRIC OXIDE;

CHAPERONE; CHAPERONIN 60; CYTOCHROME C OXIDASE; GELDANAMYCIN; GINSENOSIDE RE; HEAT SHOCK PROTEIN 90; LEUCINE RICH PENTRATRICOPEPTIDE REPEAT CONTAINING PROTEIN; MITOCHONDRIAL PROTEIN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PROTEIN PINK1; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CYTOCHROME C OXIDASE DEFICIENCY; DOWN REGULATION; DRUG MECHANISM; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME REGULATION; GENE OVEREXPRESSION; GENE SILENCING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; CHAPERONIN 60; ELECTRON TRANSPORT COMPLEX IV; GINSENOSIDES; HSP90 HEAT-SHOCK PROTEINS; HUMANS; MICE; MICE, TRANSGENIC; MITOCHONDRIA; NEOPLASM PROTEINS; NITRIC OXIDE; PARKINSON DISEASE; PLANT EXTRACTS; PROTEIN KINASES; SIGNAL TRANSDUCTION;

EID: 84871748170     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.408146     Document Type: Article

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