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Volumn 284, Issue 2, 2015, Pages 188-196

Sex-related differences in murine hepatic transcriptional and proteomic responses to TCDD

Author keywords

2,3,7,8 Tetrachlorodibenzo p dioxin; AH receptor; Aryl hydrocarbon receptor; Computational biology; Sex differences; TCDD

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; MESSENGER RNA; POLLUTANT; PROTEOME; TRANSCRIPTION FACTOR;

EID: 84932121973     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2015.02.012     Document Type: Article
Times cited : (16)

References (69)
  • 1
    • 54449087431 scopus 로고    scopus 로고
    • C-Myc and its target FoxM1 are critical downstream effectors of constitutive androstane receptor (CAR) mediated direct liver hyperplasia
    • Blanco-Bose W.E., Murphy M.J., Ehninger A., Offner S., Dubey C., Huang W., Moore D.D., Trumpp A. C-Myc and its target FoxM1 are critical downstream effectors of constitutive androstane receptor (CAR) mediated direct liver hyperplasia. Hepatology 2008, 48:1302-1311.
    • (2008) Hepatology , vol.48 , pp. 1302-1311
    • Blanco-Bose, W.E.1    Murphy, M.J.2    Ehninger, A.3    Offner, S.4    Dubey, C.5    Huang, W.6    Moore, D.D.7    Trumpp, A.8
  • 2
    • 53349100942 scopus 로고    scopus 로고
    • Transcriptomic responses to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in liver: comparison of rat and mouse
    • Boutros P.C., Yan R., Moffat I.D., Pohjanvirta R., Okey A.B. Transcriptomic responses to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in liver: comparison of rat and mouse. BMC Genomics 2008, 9:419.
    • (2008) BMC Genomics , vol.9 , pp. 419
    • Boutros, P.C.1    Yan, R.2    Moffat, I.D.3    Pohjanvirta, R.4    Okey, A.B.5
  • 3
    • 20544460373 scopus 로고    scopus 로고
    • Temporal and dose-dependent hepatic gene expression patterns in mice provide new insights into TCDD-Mediated hepatotoxicity
    • Boverhof D.R., Burgoon L.D., Tashiro C., Chittim B., Harkema J.R., Jump D.B., Zacharewski T.R. Temporal and dose-dependent hepatic gene expression patterns in mice provide new insights into TCDD-Mediated hepatotoxicity. Toxicol. Sci. 2005, 85:1048-1063.
    • (2005) Toxicol. Sci. , vol.85 , pp. 1048-1063
    • Boverhof, D.R.1    Burgoon, L.D.2    Tashiro, C.3    Chittim, B.4    Harkema, J.R.5    Jump, D.B.6    Zacharewski, T.R.7
  • 5
    • 0038381492 scopus 로고    scopus 로고
    • Resistance to 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity and abnormal liver development in mice carrying a mutation in the nuclear localization sequence of the aryl hydrocarbon receptor
    • Bunger M.K., Moran S.M., Glover E., Thomae T.L., Lahvis G.P., Lin B.C., Bradfield C.A. Resistance to 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity and abnormal liver development in mice carrying a mutation in the nuclear localization sequence of the aryl hydrocarbon receptor. J. Biol. Chem. 2003, 278:17767-17774.
    • (2003) J. Biol. Chem. , vol.278 , pp. 17767-17774
    • Bunger, M.K.1    Moran, S.M.2    Glover, E.3    Thomae, T.L.4    Lahvis, G.P.5    Lin, B.C.6    Bradfield, C.A.7
  • 7
    • 79251555660 scopus 로고    scopus 로고
    • VennDiagram: a package for the generation of highly-customizable Venn and Euler diagrams in R
    • Chen H., Boutros P.C. VennDiagram: a package for the generation of highly-customizable Venn and Euler diagrams in R. BMC Bioinformatics 2011, 12:35.
    • (2011) BMC Bioinformatics , vol.12 , pp. 35
    • Chen, H.1    Boutros, P.C.2
  • 8
    • 84868693848 scopus 로고    scopus 로고
    • Sex-specific mouse liver gene expression: genome-wide analysis of developmental changes from pre-pubertal period to young adulthood
    • Conforto T.L., Waxman D.J. Sex-specific mouse liver gene expression: genome-wide analysis of developmental changes from pre-pubertal period to young adulthood. Biol. Sex Differ. 2012, 3:9.
    • (2012) Biol. Sex Differ. , vol.3 , pp. 9
    • Conforto, T.L.1    Waxman, D.J.2
  • 10
    • 71849106314 scopus 로고    scopus 로고
    • Characterization of a new cytochrome P450 enzyme, CYP2S1, in rats: its regulation by aryl hydrocarbon receptor agonists
    • Deb S., Bandiera S.M. Characterization of a new cytochrome P450 enzyme, CYP2S1, in rats: its regulation by aryl hydrocarbon receptor agonists. Toxicology 2010, 267:91-98.
    • (2010) Toxicology , vol.267 , pp. 91-98
    • Deb, S.1    Bandiera, S.M.2
  • 11
    • 0029118476 scopus 로고
    • Xenobiotic-inducible transcription of cytochrome P450 genes
    • Denison M.S., Whitlock J.P. Xenobiotic-inducible transcription of cytochrome P450 genes. J. Biol. Chem. 1995, 270:18175-18178.
    • (1995) J. Biol. Chem. , vol.270 , pp. 18175-18178
    • Denison, M.S.1    Whitlock, J.P.2
  • 12
    • 79955113370 scopus 로고    scopus 로고
    • Differences in TCDD-elicited gene expression profiles in human HepG2, mouse Hepa1c1c7 and rat H4IIE hepatoma cells
    • Dere E., Lee A.W., Burgoon L.D., Zacharewski T.R. Differences in TCDD-elicited gene expression profiles in human HepG2, mouse Hepa1c1c7 and rat H4IIE hepatoma cells. BMC Genomics 2011, 12:193.
    • (2011) BMC Genomics , vol.12 , pp. 193
    • Dere, E.1    Lee, A.W.2    Burgoon, L.D.3    Zacharewski, T.R.4
  • 13
    • 0028968614 scopus 로고
    • Dose-response relationships of tissue distribution and induction of CYP1A1 and CYP1A2 enzymatic activities following acute exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice
    • Diliberto J.J., Akubue P.I., Luebke R.W., Birnbaum L.S. Dose-response relationships of tissue distribution and induction of CYP1A1 and CYP1A2 enzymatic activities following acute exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice. Toxicol. Appl. Pharmacol. 1995, 130:197-208.
    • (1995) Toxicol. Appl. Pharmacol. , vol.130 , pp. 197-208
    • Diliberto, J.J.1    Akubue, P.I.2    Luebke, R.W.3    Birnbaum, L.S.4
  • 14
    • 0030250623 scopus 로고    scopus 로고
    • Gender differences in the mechanism of dioxin toxicity in rodents and in nonhuman primates
    • Enan E., Overstreet J.W., Matsumura F., VandeVoort C.A., Lasley B.L. Gender differences in the mechanism of dioxin toxicity in rodents and in nonhuman primates. Reprod. Toxicol. 1996, 10:401-411.
    • (1996) Reprod. Toxicol. , vol.10 , pp. 401-411
    • Enan, E.1    Overstreet, J.W.2    Matsumura, F.3    VandeVoort, C.A.4    Lasley, B.L.5
  • 15
    • 0031570778 scopus 로고    scopus 로고
    • Regulation of mouse liver flavin-containing monooxygenases 1 and 3 by sex steroids
    • Falls J.G., Ryu D.Y., Cao Y., Levi P.E., Hodgson E. Regulation of mouse liver flavin-containing monooxygenases 1 and 3 by sex steroids. Arch. Biochem. Biophys. 1997, 342:212-223.
    • (1997) Arch. Biochem. Biophys. , vol.342 , pp. 212-223
    • Falls, J.G.1    Ryu, D.Y.2    Cao, Y.3    Levi, P.E.4    Hodgson, E.5
  • 16
  • 17
    • 84876803753 scopus 로고    scopus 로고
    • Comparative analysis of temporal and dose-dependent TCDD-elicited gene expression in human, mouse, and rat primary hepatocytes
    • Forgacs A.L., Dere E., Angrish M.M., Zacharewski T.R. Comparative analysis of temporal and dose-dependent TCDD-elicited gene expression in human, mouse, and rat primary hepatocytes. Toxicol. Sci. 2013, 133:54-66.
    • (2013) Toxicol. Sci. , vol.133 , pp. 54-66
    • Forgacs, A.L.1    Dere, E.2    Angrish, M.M.3    Zacharewski, T.R.4
  • 21
    • 0019493439 scopus 로고
    • 2,3,7,8-tetrachlorodibenzo-p-dioxin: acute oral toxicity in hamsters
    • Henck J.M., New M.A., Kociba R.J., Rao K.S. 2,3,7,8-tetrachlorodibenzo-p-dioxin: acute oral toxicity in hamsters. Toxicol. Appl. Pharmacol. 1981, 59:405-407.
    • (1981) Toxicol. Appl. Pharmacol. , vol.59 , pp. 405-407
    • Henck, J.M.1    New, M.A.2    Kociba, R.J.3    Rao, K.S.4
  • 22
    • 0031682988 scopus 로고    scopus 로고
    • The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene
    • Honkakoski P., Zelko I., Sueyoshi T., Negishi M. The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene. Mol. Cell. Biol. 1998, 18:5652-5658.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 5652-5658
    • Honkakoski, P.1    Zelko, I.2    Sueyoshi, T.3    Negishi, M.4
  • 23
    • 22344451423 scopus 로고    scopus 로고
    • Xenobiotic stress induces hepatomegaly and liver tumors via the nuclear receptor constitutive androstane receptor
    • Huang W., Zhang J., Washington M., Liu J., Parant J.M., Lozano G., Moore D.D. Xenobiotic stress induces hepatomegaly and liver tumors via the nuclear receptor constitutive androstane receptor. Mol. Endocrinol. 2005, 19:1646-1653.
    • (2005) Mol. Endocrinol. , vol.19 , pp. 1646-1653
    • Huang, W.1    Zhang, J.2    Washington, M.3    Liu, J.4    Parant, J.M.5    Lozano, G.6    Moore, D.D.7
  • 25
    • 55749094855 scopus 로고    scopus 로고
    • An integrated software system for analyzing ChIP-chip and ChIP-seq data
    • Ji H., Jiang H., Ma W., Johnson D.S., Myers R.M., Wong W.H. An integrated software system for analyzing ChIP-chip and ChIP-seq data. Nat. Biotechnol. 2008, 26:1293-1300.
    • (2008) Nat. Biotechnol. , vol.26 , pp. 1293-1300
    • Ji, H.1    Jiang, H.2    Ma, W.3    Johnson, D.S.4    Myers, R.M.5    Wong, W.H.6
  • 28
    • 85041813459 scopus 로고    scopus 로고
    • Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research
    • Kilkenny C., Browne W.J., Cuthill I.C., Emerson M., Altman D.G. Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research. PLoS Biol. 2010, 8:e1000412.
    • (2010) PLoS Biol. , vol.8 , pp. e1000412
    • Kilkenny, C.1    Browne, W.J.2    Cuthill, I.C.3    Emerson, M.4    Altman, D.G.5
  • 29
    • 0842308115 scopus 로고    scopus 로고
    • Primary structure and inducibility by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) of aryl hydrocarbon receptor repressor in a TCDD-sensitive and a TCDD-resistant rat strain
    • Korkalainen M., Tuomisto J., Pohjanvirta R. Primary structure and inducibility by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) of aryl hydrocarbon receptor repressor in a TCDD-sensitive and a TCDD-resistant rat strain. Biochem. Biophys. Res. Commun. 2004, 315:123-131.
    • (2004) Biochem. Biophys. Res. Commun. , vol.315 , pp. 123-131
    • Korkalainen, M.1    Tuomisto, J.2    Pohjanvirta, R.3
  • 30
    • 59149089822 scopus 로고    scopus 로고
    • Lung development in the Holtzman rat is adversely affected by gestational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Kransler K.M., McGarrigle B.P., Swartz D.D., Olson J.R. Lung development in the Holtzman rat is adversely affected by gestational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol. Sci. 2009, 107:498-511.
    • (2009) Toxicol. Sci. , vol.107 , pp. 498-511
    • Kransler, K.M.1    McGarrigle, B.P.2    Swartz, D.D.3    Olson, J.R.4
  • 31
    • 84884731992 scopus 로고    scopus 로고
    • Sex differences in the circadian variation of cytochrome p450 genes and corresponding nuclear receptors in mouse liver
    • Lu Y.F., Jin T., Xu Y., Zhang D., Wu Q., Zhang Y.K., Liu J. Sex differences in the circadian variation of cytochrome p450 genes and corresponding nuclear receptors in mouse liver. Chronobiol. Int. 2013, 30:1135-1143.
    • (2013) Chronobiol. Int. , vol.30 , pp. 1135-1143
    • Lu, Y.F.1    Jin, T.2    Xu, Y.3    Zhang, D.4    Wu, Q.5    Zhang, Y.K.6    Liu, J.7
  • 32
    • 2442485772 scopus 로고    scopus 로고
    • The nuclear receptor CAR is a regulator of thyroid hormone metabolism during caloric restriction
    • Maglich J.M., Watson J., McMillen P.J., Goodwin B., Willson T.M., Moore J.T. The nuclear receptor CAR is a regulator of thyroid hormone metabolism during caloric restriction. J. Biol. Chem. 2004, 279:19832-19838.
    • (2004) J. Biol. Chem. , vol.279 , pp. 19832-19838
    • Maglich, J.M.1    Watson, J.2    McMillen, P.J.3    Goodwin, B.4    Willson, T.M.5    Moore, J.T.6
  • 33
    • 64249083389 scopus 로고    scopus 로고
    • The nuclear receptor CAR (NR1I3) regulates serum triglyceride levels under conditions of metabolic stress
    • Maglich J.M., Lobe D.C., Moore J.T. The nuclear receptor CAR (NR1I3) regulates serum triglyceride levels under conditions of metabolic stress. J. Lipid Res. 2009, 50:439-445.
    • (2009) J. Lipid Res. , vol.50 , pp. 439-445
    • Maglich, J.M.1    Lobe, D.C.2    Moore, J.T.3
  • 35
    • 84884956374 scopus 로고    scopus 로고
    • Estrogen receptor alpha can selectively repress dioxin receptor-mediated gene expression by targeting DNA methylation
    • Marques M., Laflamme L., Gaudreau L. Estrogen receptor alpha can selectively repress dioxin receptor-mediated gene expression by targeting DNA methylation. Nucleic Acids Res. 2013, 41:8094-8106.
    • (2013) Nucleic Acids Res. , vol.41 , pp. 8094-8106
    • Marques, M.1    Laflamme, L.2    Gaudreau, L.3
  • 38
    • 77951210260 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor (AHR)-regulated transcriptomic changes in rats sensitive or resistant to major dioxin toxicities
    • Moffat I.D., Boutros P.C., Chen H., Okey A.B., Pohjanvirta R. Aryl hydrocarbon receptor (AHR)-regulated transcriptomic changes in rats sensitive or resistant to major dioxin toxicities. BMC Genomics 2010, 11:263.
    • (2010) BMC Genomics , vol.11 , pp. 263
    • Moffat, I.D.1    Boutros, P.C.2    Chen, H.3    Okey, A.B.4    Pohjanvirta, R.5
  • 39
    • 84873868228 scopus 로고    scopus 로고
    • Comparison of TCDD-elicited genome-wide hepatic gene expression in Sprague-Dawley rats and C57BL/6 mice
    • Nault R., Kim S., Zacharewski T.R. Comparison of TCDD-elicited genome-wide hepatic gene expression in Sprague-Dawley rats and C57BL/6 mice. Toxicol. Appl. Pharmacol. 2013, 267:184-191.
    • (2013) Toxicol. Appl. Pharmacol. , vol.267 , pp. 184-191
    • Nault, R.1    Kim, S.2    Zacharewski, T.R.3
  • 40
    • 0027922810 scopus 로고
    • Role of the Ah receptor and the dioxin-inducible [Ah] gene battery in toxicity, cancer, and signal transduction
    • Nebert D.W., Puga A., Vasiliou V. Role of the Ah receptor and the dioxin-inducible [Ah] gene battery in toxicity, cancer, and signal transduction. Ann. N. Y. Acad. Sci. 1993, 685:624-640.
    • (1993) Ann. N. Y. Acad. Sci. , vol.685 , pp. 624-640
    • Nebert, D.W.1    Puga, A.2    Vasiliou, V.3
  • 41
    • 78549278788 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor nuclear translocator in hepatocytes is required for aryl hydrocarbon receptor-mediated adaptive and toxic responses in liver
    • Nukaya M., Walisser J.A., Moran S.M., Kennedy G.D., Bradfield C.A. Aryl hydrocarbon receptor nuclear translocator in hepatocytes is required for aryl hydrocarbon receptor-mediated adaptive and toxic responses in liver. Toxicol. Sci. 2010, 118:554-563.
    • (2010) Toxicol. Sci. , vol.118 , pp. 554-563
    • Nukaya, M.1    Walisser, J.A.2    Moran, S.M.3    Kennedy, G.D.4    Bradfield, C.A.5
  • 42
    • 62549152182 scopus 로고    scopus 로고
    • Transgenic mouse lines expressing rat AH receptor variants-a new animal model for research on AH receptor function and dioxin toxicity mechanisms
    • Pohjanvirta R. Transgenic mouse lines expressing rat AH receptor variants-a new animal model for research on AH receptor function and dioxin toxicity mechanisms. Toxicol. Appl. Pharmacol. 2009, 236:166-182.
    • (2009) Toxicol. Appl. Pharmacol. , vol.236 , pp. 166-182
    • Pohjanvirta, R.1
  • 43
    • 0028588925 scopus 로고
    • Short-term toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in laboratory animals: effects, mechanisms, and animal models
    • Pohjanvirta R., Tuomisto J. Short-term toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in laboratory animals: effects, mechanisms, and animal models. Pharmacol. Rev. 1994, 46:483-549.
    • (1994) Pharmacol. Rev. , vol.46 , pp. 483-549
    • Pohjanvirta, R.1    Tuomisto, J.2
  • 44
    • 0025215179 scopus 로고
    • Tissue distribution, metabolism, and excretion of 14C-TCDD in a TCDD-susceptible and a TCDD-resistant rat strain
    • Pohjanvirta R., Vartiainen T., Uusi-Rauva A., Monkkonen J., Tuomisto J. Tissue distribution, metabolism, and excretion of 14C-TCDD in a TCDD-susceptible and a TCDD-resistant rat strain. Pharmacol. Toxicol. 1990, 66:93-100.
    • (1990) Pharmacol. Toxicol. , vol.66 , pp. 93-100
    • Pohjanvirta, R.1    Vartiainen, T.2    Uusi-Rauva, A.3    Monkkonen, J.4    Tuomisto, J.5
  • 45
    • 0027257203 scopus 로고
    • Comparative acute lethality of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), 1,2,3,7,8-pentachlorodibenzo-p-dioxin and 1,2,3,4,7,8-hexachlorodibenzo-p-dioxin in the most TCDD-susceptible and the most TCDD-resistant rat strain
    • Pohjanvirta R., Unkila M., Tuomisto J. Comparative acute lethality of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), 1,2,3,7,8-pentachlorodibenzo-p-dioxin and 1,2,3,4,7,8-hexachlorodibenzo-p-dioxin in the most TCDD-susceptible and the most TCDD-resistant rat strain. Pharmacol. Toxicol. 1993, 73:52-56.
    • (1993) Pharmacol. Toxicol. , vol.73 , pp. 52-56
    • Pohjanvirta, R.1    Unkila, M.2    Tuomisto, J.3
  • 46
    • 0031845222 scopus 로고    scopus 로고
    • Point mutation in intron sequence causes altered carboxyl-terminal structure in the aryl hydrocarbon receptor of the most 2,3,7,8-tetrachlorodibenzo-p-dioxin-resistant rat strain
    • Pohjanvirta R., Wong J.M., Li W., Harper P.A., Tuomisto J., Okey A.B. Point mutation in intron sequence causes altered carboxyl-terminal structure in the aryl hydrocarbon receptor of the most 2,3,7,8-tetrachlorodibenzo-p-dioxin-resistant rat strain. Mol. Pharmacol. 1998, 54:86-93.
    • (1998) Mol. Pharmacol. , vol.54 , pp. 86-93
    • Pohjanvirta, R.1    Wong, J.M.2    Li, W.3    Harper, P.A.4    Tuomisto, J.5    Okey, A.B.6
  • 50
    • 84908134174 scopus 로고    scopus 로고
    • Identification of reference proteins for western blot analyses in mouse model systems of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) toxicity
    • Prokopec S.D., Watson J.D., Pohjanvirta R., Boutros P.C. Identification of reference proteins for western blot analyses in mouse model systems of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) toxicity. PLoS ONE 2014, 9(10):e110730.
    • (2014) PLoS ONE , vol.9 , Issue.10 , pp. e110730
    • Prokopec, S.D.1    Watson, J.D.2    Pohjanvirta, R.3    Boutros, P.C.4
  • 54
    • 57049157091 scopus 로고    scopus 로고
    • Dioxin-like compounds in agricultural soils near e-waste recycling sites from Taizhou area, China: chemical and bioanalytical characterization
    • Shen C., Chen Y., Huang S., Wang Z., Yu C., Qiao M., Xu Y., Setty K., Zhang J., Zhu Y., Lin Q. Dioxin-like compounds in agricultural soils near e-waste recycling sites from Taizhou area, China: chemical and bioanalytical characterization. Environ. Int. 2009, 35:50-55.
    • (2009) Environ. Int. , vol.35 , pp. 50-55
    • Shen, C.1    Chen, Y.2    Huang, S.3    Wang, Z.4    Yu, C.5    Qiao, M.6    Xu, Y.7    Setty, K.8    Zhang, J.9    Zhu, Y.10    Lin, Q.11
  • 55
    • 40949120956 scopus 로고    scopus 로고
    • Toxicogenomic analysis of gender, chemical, and dose effects in livers of TCDD- or aroclor 1254-exposed rats using a multifactor linear model
    • Silkworth J.B., Carlson E.A., McCulloch C., Illouz K., Goodwin S., Sutter T.R. Toxicogenomic analysis of gender, chemical, and dose effects in livers of TCDD- or aroclor 1254-exposed rats using a multifactor linear model. Toxicol. Sci. 2008, 102:291-309.
    • (2008) Toxicol. Sci. , vol.102 , pp. 291-309
    • Silkworth, J.B.1    Carlson, E.A.2    McCulloch, C.3    Illouz, K.4    Goodwin, S.5    Sutter, T.R.6
  • 56
    • 4544341015 scopus 로고    scopus 로고
    • Linear models and empirical bayes methods for assessing differential expression in microarray experiments
    • (Article3)
    • Smyth G.K. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat. Appl. Genet. Mol. Biol. 2004, 3. (Article3).
    • (2004) Stat. Appl. Genet. Mol. Biol. , vol.3
    • Smyth, G.K.1
  • 60
    • 0031194864 scopus 로고    scopus 로고
    • In utero and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin: effects on development of the male and female reproductive system of the mouse
    • Theobald H.M., Peterson R.E. In utero and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin: effects on development of the male and female reproductive system of the mouse. Toxicol. Appl. Pharmacol. 1997, 145:124-135.
    • (1997) Toxicol. Appl. Pharmacol. , vol.145 , pp. 124-135
    • Theobald, H.M.1    Peterson, R.E.2
  • 62
    • 30044452058 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor regulates distinct dioxin-dependent and dioxin-independent gene batteries
    • Tijet N., Boutros P.C., Moffat I.D., Okey A.B., Tuomisto J., Pohjanvirta R. Aryl hydrocarbon receptor regulates distinct dioxin-dependent and dioxin-independent gene batteries. Mol. Pharmacol. 2006, 69:140-153.
    • (2006) Mol. Pharmacol. , vol.69 , pp. 140-153
    • Tijet, N.1    Boutros, P.C.2    Moffat, I.D.3    Okey, A.B.4    Tuomisto, J.5    Pohjanvirta, R.6
  • 65
    • 77956322425 scopus 로고    scopus 로고
    • Nuclear receptor CAR represses TNFalpha-induced cell death by interacting with the anti-apoptotic GADD45B
    • Yamamoto Y., Moore R., Flavell R.A., Lu B., Negishi M. Nuclear receptor CAR represses TNFalpha-induced cell death by interacting with the anti-apoptotic GADD45B. PLoS ONE 2010, 5:e10121.
    • (2010) PLoS ONE , vol.5 , pp. e10121
    • Yamamoto, Y.1    Moore, R.2    Flavell, R.A.3    Lu, B.4    Negishi, M.5
  • 66
    • 80155177963 scopus 로고    scopus 로고
    • Nuclear receptor CAR (NR1I3) is essential for DDC-induced liver injury and oval cell proliferation in mouse liver
    • Yamazaki Y., Moore R., Negishi M. Nuclear receptor CAR (NR1I3) is essential for DDC-induced liver injury and oval cell proliferation in mouse liver. Lab. Investig. 2011, 91:1624-1633.
    • (2011) Lab. Investig. , vol.91 , pp. 1624-1633
    • Yamazaki, Y.1    Moore, R.2    Negishi, M.3


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