TCDD dysregulation of 13 AHR-target genes in rat liver

Toxicology and Applied Pharmacology

Volumn 274, Issue 3, 2014, Pages 445-454

  Watson, John D ^a   Prokopec, Stephenie D ^a   Smith, Ashley B ^a   Okey, Allan B ^b   Pohjanvirta, Raimo ^c,d   Boutros, Paul C ^a,b,e  

^a ONTARIO INSTITUTE FOR CANCER RESEARCH   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^d UNIVERSITY OF HELSINKI   (Finland)

^e UNIVERSITY OF TORONTO   (Canada)

Author keywords

2,3,7,8 Tetrachlorodibenzo p dioxin; Aryl hydrocarbon receptor; Dose response; MRNA abundance; TCDD induced toxicity; Time course

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; ALDEHYDE DEHYDROGENASE; ALDEHYDE DEHYDROGENASE 3A1; AROMATIC HYDROCARBON RECEPTOR; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 1B1; CYTOCHROME P450 2A1; CYTOCHROME P450 2S1; DIMETHYLANILINE MONOOXYGENASE; FLAVIN CONTAINING MONOOXYGENASE 1; INDOLETHYLAMINE N METHYLTRANSFERASE; MESSENGER RNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN METHYLTRANSFERASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE QUINONE 1; TIPARP PROTEIN; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG EXPOSURE; DRUG SENSITIVITY; GENE EXPRESSION; GENE TARGETING; LIVER; LIVER TOXICITY; MALE; MEDIATOR; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN FUNCTION; RAT; RAT STRAIN; SINGLE DRUG DOSE; STRAIN DIFFERENCE;

2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN; ARYL HYDROCARBON RECEPTOR; DOSE-RESPONSE; MRNA ABUNDANCE; TCDD-INDUCED TOXICITY; TIME COURSE;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; CYTOCHROMES; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; LIVER; MALE; NAD(P)H DEHYDROGENASE (QUINONE); NF-E2-RELATED FACTOR 2; RATS; RATS, LONG-EVANS; RATS, WISTAR; RECEPTORS, ARYL HYDROCARBON; RNA, MESSENGER; STEROID HYDROXYLASES; TETRACHLORODIBENZODIOXIN; XENOBIOTICS;

EID: 84892465505     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2013.12.004     Document Type: Article

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