Loss of teratogenic response to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice lacking the Ah (dioxin) receptor

Genes to Cells

Volumn 2, Issue 10, 1997, Pages 645-654

  Mimura, Junsei ^a   Yamashita, Keisuke ^b   Nakamura, Kenji ^c   Morita, Masanobu ^a   Takagi, Toshio N ^b   Nakao, Kazuki ^c   Ema, Masatsugu ^a   Sogawa, Kazuhiro ^a   Yasuda, Mineo ^b   Katsuki, Motoya ^c   Fujii Kuriyama, Yoshiaki ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b HIROSHIMA UNIV SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON RECEPTOR; MESSENGER RNA; TERATOGENIC AGENT;

ANIMAL; ARTICLE; CONGENITAL MALFORMATION; ENVIRONMENTAL EXPOSURE; FEMALE; GENE TARGETING; GENETICS; KIDNEY; MOUSE; MOUSE MUTANT; MUTAGENESIS; PALATE; PREGNANCY;

ANIMALS; FEMALE; GENE TARGETING; KIDNEY; MATERNAL EXPOSURE; MICE; MICE, MUTANT STRAINS; MUTAGENESIS; PALATE; PREGNANCY; RECEPTORS, ARYL HYDROCARBON; RNA, MESSENGER; TERATOGENS; TETRACHLORODIBENZODIOXIN;

EID: 0031241140     PISSN: 13569597     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2443.1997.1490345.x     Document Type: Article

References (8)

1. Abbott, B.D. & Birnbaum, L.S. (1990) TCDD-induced altered expression of growth factors may have a role in producing cleft palate and enhancing the incidence of clefts after coadministration of retinoic acid and TCDD. Toxicol. Appl. Pharmacol. 106, 418-432.
2. Abbott, B.D. & Birnbaum, L.S. (1991) Effects of TCDD on embryonic ureteric epitherial EGF receptor expression and cell proliferation. Teratology 41, 71-84.
3. Abbott, B.D., Birnbaum, L.S. & Dibetto, J.J. (1996) Rapid distribution of, 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) to embryonic tissues in C57BL/6N mice and correlation with palatal uptake in vitro. Toxicol. Appl. Pharmacol. 141, 256-263.
4. Abbott, B.D., Birnbaum, L.S. & Perdew, G.H. (1995) Developmental expression of two members of a new class of transcription factor: I. expression of aryl hydrocarbon receptor in the C57BL/6N mouse embryo. Dev. Dynam. 204, 133-143.
5. Abbott, B.D., Birnbaum, L.S. & Pratt, R.M. (1987) TCDD-induced hyperplasia of the ureteral epitherium produces hydronephrosis in murine fetuses. Teratology 35, 329-334.
6. Abbott, B., Perdew, G.H. & Birnbaum, L.S. (1994) Ah receptor in embryonic mouse palate and effects of TCDD on receptor expression. Toxicol. Appl. Pharmacol. 126, 16-25.
7. Abbott, B.D. & Probst, M.R. (1995) Developmental expression of two member of a new class of transcrition factor: II. expression of aryl hydrocarbon receptor nuclear translocator in the C57BL/6N mouse embryo. Develop. Dynam. 204, 144-155.
8. Birnbaum, L.S. & Abbott, B. (1997) Effect of dioxin on growth factor and receptor expression in developing palate. In: Methods in Developmental Toxicology and Biology (eds S. Klug & R. Thiel), pp. 51-63. London: Blackwell Science.